Viral Proteases and Antiviral Protease Inhibitor Therapy

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  • Author : Uwe Lendeckel
  • Publisher : Springer Science & Business Media
  • Pages : 132 pages
  • ISBN : 9048123488
  • Rating : /5 from reviews
CLICK HERE TO GET THIS BOOK >>>Viral Proteases and Antiviral Protease Inhibitor Therapy

Download or Read online Viral Proteases and Antiviral Protease Inhibitor Therapy full in PDF, ePub and kindle. this book written by Uwe Lendeckel and published by Springer Science & Business Media which was released on 19 June 2009 with total page 132 pages. We cannot guarantee that Viral Proteases and Antiviral Protease Inhibitor Therapy book is available in the library, click Get Book button and read full online book in your kindle, tablet, IPAD, PC or mobile whenever and wherever You Like. The 8th volume in the Proteases in Biology and Disease series focuses on the role of proteases in virus function and their potential as anti-viral targets. Viral infections are still difficult to threat and some remained life-threatening diseases in spite of antiviral drug research over decades. Proteases are still regarded as an Achilles’ heel of the pathogens and, thus, protease inhibitors may help to handle the known and the emerging viral threads. The book discusses viral proteases of the most important pathogenic viruses, responsible for severe diseases: AIDS, SARS, Hepatitis, Cytomegalovirus, T-cell lymphotropic virus, Picornavirus. This book focuses specifically on the viral proteases, crucial prerequisites for viral entry into cells and viral replication. Viral proteases represent an important pharmaceutical target. The current stage of protease inhibitor development and therapy are summarised and discussed by experts in the field. This volume represents a timely and valuable continuation of the Proteases in Biology and Disease series. The reader will learn the potential for proteases as targets for effective anti-virals. This book will be a valuable source of information on viral proteases and provoke further research in this important field.

Viral Proteases and Antiviral Protease Inhibitor Therapy

Viral Proteases and Antiviral Protease Inhibitor Therapy
  • Author : Uwe Lendeckel,Nigel M. Hooper
  • Publisher : Springer Science & Business Media
  • Release : 19 June 2009
GET THIS BOOK Viral Proteases and Antiviral Protease Inhibitor Therapy

The 8th volume in the Proteases in Biology and Disease series focuses on the role of proteases in virus function and their potential as anti-viral targets. Viral infections are still difficult to threat and some remained life-threatening diseases in spite of antiviral drug research over decades. Proteases are still regarded as an Achilles’ heel of the pathogens and, thus, protease inhibitors may help to handle the known and the emerging viral threads. The book discusses viral proteases of the most

Viral Proteases and Their Inhibitors

Viral Proteases and Their Inhibitors
  • Author : Satya Prakash Gupta
  • Publisher : Academic Press
  • Release : 03 July 2017
GET THIS BOOK Viral Proteases and Their Inhibitors

Viral Proteases and Their Inhibitors provides a thorough examination of viral proteases from their molecular components, to therapeutic applications. As information on three dimensional structures and biological functions of these viral proteases become known, unexpected protein folds and unique mechanisms of proteolysis are realized. This book investigates how this facilitates the design and development of potent antiviral agents used against life-threatening viruses. Users will find descriptions of each virus that detail the structure and function of viral proteases, discuss the

Medical Aspects of Proteases and Protease Inhibitors

Medical Aspects of Proteases and Protease Inhibitors
  • Author : Nobuhiko Katunuma,H. Kido,H. Fritz,J. Travis
  • Publisher : IOS Press
  • Release : 21 June 1997
GET THIS BOOK Medical Aspects of Proteases and Protease Inhibitors

The work presents articles on proteases and their inhibitors as mediators of biological functions. Topics addressed: cathepsin B and L; MHC and peptide interaction; procathepsin L; cysteine proteinases; selective neuronal cell death; HIV and influenza virus; tumor invasion; gingivitis; bacterial infection. Readers: professionals in the area of molecular medicine, biochemists, molecular biologists, clinical pharmacologists, pharmaceutical companies.

Viral Proteases and Antiviral Protease Inhibitor Therapy

Viral Proteases and Antiviral Protease Inhibitor Therapy
  • Author : Uwe Lendeckel,Nigel M. Hooper
  • Publisher : Springer
  • Release : 29 August 2009
GET THIS BOOK Viral Proteases and Antiviral Protease Inhibitor Therapy

The 8th volume in the Proteases in Biology and Disease series focuses on the role of proteases in virus function and their potential as anti-viral targets. Viral infections are still difficult to threat and some remained life-threatening diseases in spite of antiviral drug research over decades. Proteases are still regarded as an Achilles’ heel of the pathogens and, thus, protease inhibitors may help to handle the known and the emerging viral threads. The book discusses viral proteases of the most

Proteases and Their Inhibitors in Cancer Metastasis

Proteases and Their Inhibitors in Cancer Metastasis
  • Author : J-M. Foidart,R.J. Muschel
  • Publisher : Springer Science & Business Media
  • Release : 21 June 2021
GET THIS BOOK Proteases and Their Inhibitors in Cancer Metastasis

In recent years, serine proteases and matrix metalloproteinases (MMPs) have gained considerable attention in tumor biology. For most of these proteases, their expression is a reliable indication of ongoing tissue remodeling. This book provides a comprehensive evaluation of the mechanisms of action of proteases and their inhibitors in tumor biology. The first part provides the reader with a selective overview of the molecular biology of serine proteases, MMPs and their physiological inhibitors. The most important proteases and their physiological as

Proteases and Their Receptors in Inflammation

Proteases and Their Receptors in Inflammation
  • Author : Nathalie Vergnolle,Michel Chignard
  • Publisher : Springer Science & Business Media
  • Release : 03 August 2011
GET THIS BOOK Proteases and Their Receptors in Inflammation

Proteases are everywhere from prokaryotes to eukaryotes, from virus to bacteria and in all human tissues, playing a role in many biological functions. Among these functions, the inflammatory reaction is of particular interest. In inflamed tissues, proteases can have a microbial and/or host origin and are involved not only in tissue remodeling, but also in specific signaling to resident or inflammatory cells, thereby contributing to the innate immune response. This volume presents all advances in our knowledge of the

Aspartic Acid Proteases as Therapeutic Targets

Aspartic Acid Proteases as Therapeutic Targets
  • Author : Arun K. Ghosh
  • Publisher : John Wiley & Sons
  • Release : 04 August 2011
GET THIS BOOK Aspartic Acid Proteases as Therapeutic Targets

In this ground-breaking practical reference, the family of aspartic acid proteases is described from a drug developer's perspective. The first part provides a general introduction to the family of aspartic acid proteases, their physiological functions, molecular structure and inhibition. Parts two to five present various case studies of successful protease inhibitor drug design and development, as well as current and potential uses of such inhibitors in pharmaceutical medicine, covering the major therapeutic targets HIV-1 protease, renin, beta-secretase, gamma-secretase,plasmepsins and

Characterization of Viral Proteases from Norwalk Virus Poliovirus and Transmissible Gastroenteritis Virus Using a Fluorescence Resonance Energy Transfer Assay

Characterization of Viral Proteases from Norwalk Virus  Poliovirus  and Transmissible Gastroenteritis Virus Using a Fluorescence Resonance Energy Transfer Assay
  • Author : Venkata Kiran Pasupulleti
  • Publisher : Unknown
  • Release : 21 June 2021
GET THIS BOOK Characterization of Viral Proteases from Norwalk Virus Poliovirus and Transmissible Gastroenteritis Virus Using a Fluorescence Resonance Energy Transfer Assay

Positive sense RNA viruses include diverse groups of viruses that cause a wide variety of diseases in humans and animals. Most of these viruses encode proteases that cleave the viral polyprotein into intermediate or mature functional proteins during virus replication. As these proteases play a critical role in virus replication, they represent an attractive target for the development of antiviral drugs. In this study, the main goal was to establish assay systems and characterize the enzymatic activity of related proteases

Human Blood Plasma Proteins

Human Blood Plasma Proteins
  • Author : Johann Schaller,Simon Gerber,Urs Kaempfer,Sofia Lejon,Christian Trachsel
  • Publisher : John Wiley & Sons
  • Release : 03 June 2008
GET THIS BOOK Human Blood Plasma Proteins

The first textbook on blood plasma proteins published for ten years, this book gives an overview of human blood plasma proteins with special emphasis on their structure and function and, if known, also in relation to pathological states and diseases.