Viral Proteases and Antiviral Protease Inhibitor Therapy

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  • Author : Uwe Lendeckel
  • Publisher : Springer Science & Business Media
  • Pages : 132 pages
  • ISBN : 9048123488
  • Rating : /5 from reviews
CLICK HERE TO GET THIS BOOK >>>Viral Proteases and Antiviral Protease Inhibitor Therapy

Download or Read online Viral Proteases and Antiviral Protease Inhibitor Therapy full in PDF, ePub and kindle. this book written by Uwe Lendeckel and published by Springer Science & Business Media which was released on 19 June 2009 with total page 132 pages. We cannot guarantee that Viral Proteases and Antiviral Protease Inhibitor Therapy book is available in the library, click Get Book button and read full online book in your kindle, tablet, IPAD, PC or mobile whenever and wherever You Like. The 8th volume in the Proteases in Biology and Disease series focuses on the role of proteases in virus function and their potential as anti-viral targets. Viral infections are still difficult to threat and some remained life-threatening diseases in spite of antiviral drug research over decades. Proteases are still regarded as an Achilles’ heel of the pathogens and, thus, protease inhibitors may help to handle the known and the emerging viral threads. The book discusses viral proteases of the most important pathogenic viruses, responsible for severe diseases: AIDS, SARS, Hepatitis, Cytomegalovirus, T-cell lymphotropic virus, Picornavirus. This book focuses specifically on the viral proteases, crucial prerequisites for viral entry into cells and viral replication. Viral proteases represent an important pharmaceutical target. The current stage of protease inhibitor development and therapy are summarised and discussed by experts in the field. This volume represents a timely and valuable continuation of the Proteases in Biology and Disease series. The reader will learn the potential for proteases as targets for effective anti-virals. This book will be a valuable source of information on viral proteases and provoke further research in this important field.

Viral Proteases and Antiviral Protease Inhibitor Therapy

Viral Proteases and Antiviral Protease Inhibitor Therapy
  • Author : Uwe Lendeckel,Nigel M. Hooper
  • Publisher : Springer Science & Business Media
  • Release : 19 June 2009
GET THIS BOOK Viral Proteases and Antiviral Protease Inhibitor Therapy

The 8th volume in the Proteases in Biology and Disease series focuses on the role of proteases in virus function and their potential as anti-viral targets. Viral infections are still difficult to threat and some remained life-threatening diseases in spite of antiviral drug research over decades. Proteases are still regarded as an Achilles’ heel of the pathogens and, thus, protease inhibitors may help to handle the known and the emerging viral threads. The book discusses viral proteases of the most

Viral Proteases and Their Inhibitors

Viral Proteases and Their Inhibitors
  • Author : Satya Prakash Gupta
  • Publisher : Academic Press
  • Release : 03 July 2017
GET THIS BOOK Viral Proteases and Their Inhibitors

Viral Proteases and Their Inhibitors provides a thorough examination of viral proteases from their molecular components, to therapeutic applications. As information on three dimensional structures and biological functions of these viral proteases become known, unexpected protein folds and unique mechanisms of proteolysis are realized. This book investigates how this facilitates the design and development of potent antiviral agents used against life-threatening viruses. Users will find descriptions of each virus that detail the structure and function of viral proteases, discuss the

Viral Proteases and Antiviral Protease Inhibitor Therapy

Viral Proteases and Antiviral Protease Inhibitor Therapy
  • Author : Uwe Lendeckel,Nigel M. Hooper
  • Publisher : Springer
  • Release : 29 August 2009
GET THIS BOOK Viral Proteases and Antiviral Protease Inhibitor Therapy

The 8th volume in the Proteases in Biology and Disease series focuses on the role of proteases in virus function and their potential as anti-viral targets. Viral infections are still difficult to threat and some remained life-threatening diseases in spite of antiviral drug research over decades. Proteases are still regarded as an Achilles’ heel of the pathogens and, thus, protease inhibitors may help to handle the known and the emerging viral threads. The book discusses viral proteases of the most

Viral Replication Enzymes and their Inhibitors Part A

Viral Replication Enzymes and their Inhibitors Part A
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 23 October 2021
GET THIS BOOK Viral Replication Enzymes and their Inhibitors Part A

Viral Replication Enzymes and their Inhibitors Part A, Volume 49, the latest release in the Enzymes series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of related topics. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in The Enzymes series

Proteases and Their Inhibitors in Cancer Metastasis

Proteases and Their Inhibitors in Cancer Metastasis
  • Author : J-M. Foidart,R.J. Muschel
  • Publisher : Springer Science & Business Media
  • Release : 16 May 2022
GET THIS BOOK Proteases and Their Inhibitors in Cancer Metastasis

In recent years, serine proteases and matrix metalloproteinases (MMPs) have gained considerable attention in tumor biology. For most of these proteases, their expression is a reliable indication of ongoing tissue remodeling. This book provides a comprehensive evaluation of the mechanisms of action of proteases and their inhibitors in tumor biology. The first part provides the reader with a selective overview of the molecular biology of serine proteases, MMPs and their physiological inhibitors. The most important proteases and their physiological as

Characterization of Viral Proteases from Norwalk Virus Poliovirus and Transmissible Gastroenteritis Virus Using a Fluorescence Resonance Energy Transfer Assay

Characterization of Viral Proteases from Norwalk Virus  Poliovirus  and Transmissible Gastroenteritis Virus Using a Fluorescence Resonance Energy Transfer Assay
  • Author : Venkata Kiran Pasupulleti
  • Publisher : Unknown
  • Release : 16 May 2022
GET THIS BOOK Characterization of Viral Proteases from Norwalk Virus Poliovirus and Transmissible Gastroenteritis Virus Using a Fluorescence Resonance Energy Transfer Assay

Positive sense RNA viruses include diverse groups of viruses that cause a wide variety of diseases in humans and animals. Most of these viruses encode proteases that cleave the viral polyprotein into intermediate or mature functional proteins during virus replication. As these proteases play a critical role in virus replication, they represent an attractive target for the development of antiviral drugs. In this study, the main goal was to establish assay systems and characterize the enzymatic activity of related proteases

Structure guided Design Synthesis and Evaluation of Macrocyclic and Peptidomimetic Inhibitors of Viral Proteases

Structure guided Design  Synthesis and Evaluation of Macrocyclic and Peptidomimetic Inhibitors of Viral Proteases
  • Author : Vishnu C. Damalanka
  • Publisher : Unknown
  • Release : 16 May 2022
GET THIS BOOK Structure guided Design Synthesis and Evaluation of Macrocyclic and Peptidomimetic Inhibitors of Viral Proteases

Human noroviruses are the primary cause of non-bacterial acute gastroenteritis worldwide and are associated with high morbidity and a heavy economic burden. In the U.S. alone noroviruses account for ~21 million cases, resulting in 70,000 hospitalizations and 800 deaths annually, and impact most severely the young and elderly, and immunocompromised individuals. Combating norovirus infections presents a challenge because of their high infectivity, ease of transmission, the dearth of norovirus-specific therapeutics/prophylactics and vaccines, and a poor understanding of norovirus pathophysiology. Noroviruses are

Cancer Causing Viruses and Their Inhibitors

Cancer Causing Viruses and Their Inhibitors
  • Author : Satya Prakash Gupta
  • Publisher : CRC Press
  • Release : 16 May 2014
GET THIS BOOK Cancer Causing Viruses and Their Inhibitors

Cancer-causing viruses, also called oncoviruses, play a key role in the development of certain cancers. They contribute to genetic changes that disrupt the cell cycle machinery, interfering with functions such as cell growth. Cancer-Causing Viruses and Their Inhibitors presents a plethora of research from internationally reputed contributors who discuss different types of oncoviruses, their mechanisms of invasion and growth, and their life cycles. The book begins with an overview of the oncoviruses discovered to date and includes a brief description

Applications of Metal Organic Frameworks and Their Derived Materials

Applications of Metal Organic Frameworks and Their Derived Materials
  • Author : Inamuddin,Rajender Boddula,Mohd Imran Ahamed,Abdullah M. Asiri
  • Publisher : John Wiley & Sons
  • Release : 04 May 2020
GET THIS BOOK Applications of Metal Organic Frameworks and Their Derived Materials

Metal–organic frameworks (MOFs) are porous crystalline polymers constructed by metal sites and organic building blocks. Since the discovery of MOFs in the 1990s, they have received tremendous research attention for various applications due to their high surface area, controllable morphology, tunable chemical properties, and multifunctionalities, including MOFs as precursors and self-sacrificing templates for synthesizing metal oxides, heteroatom-doped carbons, metal-atoms encapsulated carbons, and others. Thus, awareness and knowledge about MOFs and their derived nanomaterials with conceptual understanding are essential for

Retroviral Proteases

Retroviral Proteases
  • Author : Lawrence C. Kuo,Jules A. Shafer
  • Publisher : Gulf Professional Publishing
  • Release : 06 October 1994
GET THIS BOOK Retroviral Proteases

Methods included in this volume apply to the expression and characterization of retroviral proteases and their inhibitor/substrate design.

Studies on Hepatitis Viruses

Studies on Hepatitis Viruses
  • Author : Satya Prakash Gupta
  • Publisher : Academic Press
  • Release : 20 June 2018
GET THIS BOOK Studies on Hepatitis Viruses

Studies on Hepatitis Viruses: Life Cycle, Structure, Functions, and Inhibition presents the latest on this systemic infection that predominantly affects the liver with inflammation that can be acute or chronic. Hepatitis viruses have been the subject of intense study in the last twenty years, with a wealth of information related to their lifecycle, structure, functions and inhibition being presented. This book compiles the most important developments and research, giving users a very useful guide on this evolving area of virology

Cancer Leading Proteases

Cancer Leading Proteases
  • Author : Satya Prakash Gupta
  • Publisher : Academic Press
  • Release : 03 February 2020
GET THIS BOOK Cancer Leading Proteases

Cancer-Leading Proteases: Structures, Functions, and Inhibition presents a detailed discussion on the role of proteases as drug targets and how they have been utilized to develop anticancer drugs. Proteases possess outstanding diversity in their functions. Because of their unique properties, proteases are a major focus of attention for the pharmaceutical industry as potential drug targets or as diagnostic and prognostic biomarkers. This book covers the structure and functions of proteases and the chemical and biological rationale of drug design relating