Viral Polymerases and Related Proteins

• Author : Lawrence C. Kuo,David B. Olsen,Steven S. Carroll
• Publisher : Elsevier
• Release : 16 May 1996

The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. More than 270 volumes have been published (all of them still in print) and much of the material is relevant even today--truly an essential publication for researchers in all fields of life sciences. Key Features * Expression, purification, and characterization *

• Author : Satya Prakash Gupta
• Publisher : Academic Press
• Release : 29 October 2018

Viral Polymerases: Structures, Functions and Roles as Antiviral Drug Targets presents in-depth study information on the structure and functions of polymerases and their roles in the lifecycle of viruses, and as drug targets. Viral polymerases constitute a vital component in the lifecycle of many viruses, such as human immunodeficiency virus (HIV), hepatitis viruses, influenza virus, and several others. They are essentially required for the replication of viruses. Thus, the polymerases that can be found in viruses (called viral polymerases) represent

• Author : John J. Holland,Paul Ahlquist
• Publisher : CRC PressI Llc
• Release : 31 May 1988

• Author : John F. Regan
• Publisher : Unknown
• Release : 16 May 2022

Influenza is an RNA virus whose segmented genome is encapsidated into viral ribonucleoprotein complexes (vRNPs). Upon infection, the vRNPs migrate into the nucleus where transcription and replication take place. The vRNPs contain a RNA-dependent RNA polymerase that is responsible for viral transcription and replication. The polymerase is composed of three subunits, PB1, PB2, and PA. PBI has polymerase activity and PB2 is involved in viral transcription. The function of PA is unclear. To help elucidate the role of PA in

• Author : P. Chandra
• Publisher : Springer
• Release : 01 February 1979

• Author : Susan Marie Uptain
• Publisher : Unknown
• Release : 16 May 1997

• Author : Robert G. Webster,Arnold S. Monto,Thomas J. Braciale,Robert A. Lamb
• Publisher : John Wiley & Sons
• Release : 06 January 2014

The Textbook of Influenza is a comprehensive resourcecovering all aspects of influenza, from the genetic and molecularbiology of the virus through to clinical aspects of the disease andthe latest drug developments and treatments. This new edition hasbeen completely revised and reflects the integration of disciplinesconcerning the emergence, evolution, pathogenesis and control ofinfluenza viruses in the field of human and veterinary publichealth. Textbook of Influenza examines the lessons learnt fromthe latest pandemic and provides the current state of knowledge formany yet

• Author : P E. Came,L. A. Caliguiri
• Publisher : Springer Science & Business Media
• Release : 06 December 2012

" . . . the motto for the therapeutics of the future will have to be de sedibus et causis pharmacorum. " P. EHRLICH, 1909 Exciting events in the basic disciplines of virology, immunology, and pharmacology continue to advance the understanding of the pathogenesis and control of virus diseases. At the same time, the rational development of antiviral agents is attracting, to an increasing extent, the interest of workers in other disciplines. Improvements in technology facilitate the definition of potential target sites for antiviral intervention and

• Author : National Cancer Institute (U.S.). Viral Oncology Area
• Publisher : Unknown
• Release : 16 May 1971

• Author : Frans J. de Bruijn
• Publisher : John Wiley & Sons
• Release : 27 September 2011

"Handbook of Molecular Microbial Ecology I: Metagenomics and Complementary Approaches is the first comprehensive reference covering the various metagenomics in a large variety of habitats, which could not previously have been analysed without metagenomic methodology. This Volume includes topics such as species designations in microbiology, metagenomics, consortia and databases, bioinformatics, microarrays, and other metagenomics applications. This reference is ideal for researchers in metagenomics, microbiology, environmental microbiology, those working on the Human Microbiome Project, microbial geneticists, molecular microbiology, and bioinformatics"--

• Author : National Cancer Institute (U.S.)
• Publisher : Unknown
• Release : 16 May 1976

• Author : National Cancer Institute (U.S.). Viral Oncology Program
• Publisher : Unknown
• Release : 16 May 1973

• Author : Jerome Pearsall McDonnell
• Publisher : Unknown
• Release : 16 May 1971

• Author : Jonathan P. Clewley
• Publisher : CRC Press
• Release : 27 October 1994

The polymerase chain reaction (PCR) is the most sensitive method for revealing the presence of otherwise undetectable quantities of the genome of RNA or DNA of human viruses. The Polymerase Chain Reaction (PCR) for Human Viral Diagnosis addresses the urgent need to use this revolutionary technology in reference and routine diagnostic laboratories. It informs the molecular biologist of the most appropriate clinical uses for PCR and educates the clinician and medical virologist about the subtleties and benefits of gene amplification.

• Author : Kathleen L. Hefferon
• Publisher : Unknown
• Release : 16 May 2022