Understanding the Basics of QSAR for Applications in Pharmaceutical Sciences and Risk Assessment

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  • Author : Kunal Roy
  • Publisher : Academic Press
  • Pages : 484 pages
  • ISBN : 0128016337
  • Rating : /5 from reviews
CLICK HERE TO GET THIS BOOK >>>Understanding the Basics of QSAR for Applications in Pharmaceutical Sciences and Risk Assessment

Download or Read online Understanding the Basics of QSAR for Applications in Pharmaceutical Sciences and Risk Assessment full in PDF, ePub and kindle. this book written by Kunal Roy and published by Academic Press which was released on 03 March 2015 with total page 484 pages. We cannot guarantee that Understanding the Basics of QSAR for Applications in Pharmaceutical Sciences and Risk Assessment book is available in the library, click Get Book button and read full online book in your kindle, tablet, IPAD, PC or mobile whenever and wherever You Like. Understanding the Basics of QSAR for Applications in Pharmaceutical Sciences and Risk Assessment describes the historical evolution of quantitative structure-activity relationship (QSAR) approaches and their fundamental principles. This book includes clear, introductory coverage of the statistical methods applied in QSAR and new QSAR techniques, such as HQSAR and G-QSAR. Containing real-world examples that illustrate important methodologies, this book identifies QSAR as a valuable tool for many different applications, including drug discovery, predictive toxicology and risk assessment. Written in a straightforward and engaging manner, this is the ideal resource for all those looking for general and practical knowledge of QSAR methods. Includes numerous practical examples related to QSAR methods and applications Follows the Organization for Economic Co-operation and Development principles for QSAR model development Discusses related techniques such as structure-based design and the combination of structure- and ligand-based design tools

Understanding the Basics of QSAR for Applications in Pharmaceutical Sciences and Risk Assessment

Understanding the Basics of QSAR for Applications in Pharmaceutical Sciences and Risk Assessment
  • Author : Kunal Roy,Supratik Kar,Rudra Narayan Das
  • Publisher : Academic Press
  • Release : 03 March 2015
GET THIS BOOK Understanding the Basics of QSAR for Applications in Pharmaceutical Sciences and Risk Assessment

Understanding the Basics of QSAR for Applications in Pharmaceutical Sciences and Risk Assessment describes the historical evolution of quantitative structure-activity relationship (QSAR) approaches and their fundamental principles. This book includes clear, introductory coverage of the statistical methods applied in QSAR and new QSAR techniques, such as HQSAR and G-QSAR. Containing real-world examples that illustrate important methodologies, this book identifies QSAR as a valuable tool for many different applications, including drug discovery, predictive toxicology and risk assessment. Written in a straightforward

Genotoxicity

Genotoxicity
  • Author : Marcelo Larramendy,Sonia Soloneski
  • Publisher : BoD – Books on Demand
  • Release : 11 July 2018
GET THIS BOOK Genotoxicity

This book is designed to provide an overview of the different genotoxicants and their effects on living organisms, including humans. The contributions made by the specialists in this field of research are gratefully acknowledged. We hope that the information presented in this book will meet the expectations and needs of all those interested in the different aspects of the genotoxicity field. The publication of this book is of great importance to those scientists, pharmacologists, physicians and veterinarians, as well as

Methods and Algorithms for Molecular Docking Based Drug Design and Discovery

Methods and Algorithms for Molecular Docking Based Drug Design and Discovery
  • Author : Dastmalchi, Siavoush
  • Publisher : IGI Global
  • Release : 03 May 2016
GET THIS BOOK Methods and Algorithms for Molecular Docking Based Drug Design and Discovery

The role of technology in the medical field has resulted in significant developments within the pharmaceutical industry. Computational approaches have emerged as a crucial method in further advancing drug design and development. Methods and Algorithms for Molecular Docking-Based Drug Design and Discovery presents emerging research on the application of computer-assisted design methods for drugs, emphasizing the benefits and improvements that molecular docking has caused within the pharmaceutical industry. Focusing on validation methods, search algorithms, and scoring functions, this book is

Computational Nanotoxicology

Computational Nanotoxicology
  • Author : Agnieszka Gajewicz,Tomasz Puzyn
  • Publisher : CRC Press
  • Release : 20 December 2019
GET THIS BOOK Computational Nanotoxicology

The development of computational methods that support human health and environmental risk assessment of engineered nanomaterials has attracted great interest because the application of these methods enables us to fill existing experimental data gaps. However, considering the high degree of complexity and multifunctionality of engineered nanoparticles, computational methods originally developed for regular (i.e., classic) chemicals cannot always be applied explicitly in nanotoxicology. Thus, the main idea of this book is to discuss the current state of the art and

Quantitative Structure Activity Relationships in Drug Design Predictive Toxicology and Risk Assessment

Quantitative Structure Activity Relationships in Drug Design  Predictive Toxicology  and Risk Assessment
  • Author : Roy, Kunal
  • Publisher : IGI Global
  • Release : 28 February 2015
GET THIS BOOK Quantitative Structure Activity Relationships in Drug Design Predictive Toxicology and Risk Assessment

Quantitative structure-activity relationships (QSARs) represent predictive models derived from the application of statistical tools correlating biological activity or other properties of chemicals with descriptors representative of molecular structure and/or property. Quantitative Structure-Activity Relationships in Drug Design, Predictive Toxicology, and Risk Assessment discusses recent advancements in the field of QSARs with special reference to their application in drug development, predictive toxicology, and chemical risk analysis. Focusing on emerging research in the field, this book is an ideal reference source for

Computational Toxicology

Computational Toxicology
  • Author : Sean Ekins
  • Publisher : John Wiley & Sons
  • Release : 27 July 2007
GET THIS BOOK Computational Toxicology

A comprehensive analysis of state-of-the-art molecular modeling approaches and strategies applied to risk assessment for pharmaceutical and environmental chemicals This unique volume describes how the interaction of molecules with toxicologically relevant targets can be predicted using computer-based tools utilizing X-ray crystal structures or homology, receptor, pharmacophore, and quantitative structure activity relationship (QSAR) models of human proteins. It covers the in vitro models used, newer technologies, and regulatory aspects. The book offers a complete systems perspective to risk assessment prediction, discussing

Computational Toxicology

Computational Toxicology
  • Author : Bruce A. Fowler
  • Publisher : Academic Press
  • Release : 04 June 2013
GET THIS BOOK Computational Toxicology

Computational Toxicology: Methods and Applications for Risk Assessment is an essential reference on the translation of computational toxicology data into information that can be used for more informed risk assessment decision-making. This book is authored by leading international investigators who have real-world experience in relating computational toxicology methods to risk assessment. Key topics of interest include QSAR modeling, chemical mixtures, applications to metabolomic and metabonomic data sets, toxicogenomic analyses, applications to REACH informational strategies and much more. The examples provided

A Primer on QSAR QSPR Modeling

A Primer on QSAR QSPR Modeling
  • Author : Kunal Roy,Supratik Kar,Rudra Narayan Das
  • Publisher : Springer
  • Release : 11 April 2015
GET THIS BOOK A Primer on QSAR QSPR Modeling

This brief goes back to basics and describes the Quantitative structure-activity/property relationships (QSARs/QSPRs) that represent predictive models derived from the application of statistical tools correlating biological activity (including therapeutic and toxic) and properties of chemicals (drugs/toxicants/environmental pollutants) with descriptors representative of molecular structure and/or properties. It explains how the sub-discipline of Cheminformatics is used for many applications such as risk assessment, toxicity prediction, property prediction and regulatory decisions apart from drug discovery and lead optimization.

Three Dimensional QSAR

Three Dimensional QSAR
  • Author : Jean Pierre Doucet,Annick Panaye
  • Publisher : QSAR in Environmental and Health Sciences
  • Release : 21 October 2019
GET THIS BOOK Three Dimensional QSAR

"Experiencing rapid growth over the last 15 years, quantitative structure-activity relationships (QSAR) continue to evolve quickly with an explosion of new tools and techniques. These techniques now play an increasing role in drug design and chemical risk assessment. New molecular descriptors based on three-dimensional structures incorporate a range of classical approaches, including regression and PLS analysis, as well as new nonlinear approaches, such as neural networks and support vector machines. Three-Dimensional QSAR addresses the scope and limitations of different modeling techniques

Quantitative Structure Activity Relationship QSAR Models of Mutagens and Carcinogens

Quantitative Structure Activity Relationship  QSAR  Models of Mutagens and Carcinogens
  • Author : Romualdo Benigni
  • Publisher : CRC Press
  • Release : 26 February 2003
GET THIS BOOK Quantitative Structure Activity Relationship QSAR Models of Mutagens and Carcinogens

Applied with success in a number of areas, QSAR studies have become particularly popular in the rational design of drugs and pesticides. Much has been published on the principles of QSAR in this area, but not on their application s to toxic chemicals. This book provides the first comprehensive, interdisciplinary presentation of QSAR studies on

Casarett Doull s Toxicology The Basic Science of Poisons Ninth Edition

Casarett   Doull s Toxicology  The Basic Science of Poisons  Ninth Edition
  • Author : Curtis D. Klaassen
  • Publisher : McGraw Hill Professional
  • Release : 23 November 2018
GET THIS BOOK Casarett Doull s Toxicology The Basic Science of Poisons Ninth Edition

Toxicology’s gold-standard text - completely updated to reflect the latest breakthroughs and discoveries Casarett & Doull’s Toxicology: The Basic Science of Poisons, Ninth Edition equips you with an unsurpassed understanding of modern toxicology, including the key principles, concepts, mechanisms, chemical-specific toxicity, and modes of thought that are the foundation of the discipline. This trusted classic not only delivers a comprehensive review of the essential components of toxicology, it offers the most up-to-date, revealing, and in-depth look at the systemic

Casarett Doull s Toxicology The Basic Science of Poisons Eighth Edition

Casarett   Doull s Toxicology  The Basic Science of Poisons  Eighth Edition
  • Author : Curtis Klaassen
  • Publisher : McGraw Hill Professional
  • Release : 25 April 2013
GET THIS BOOK Casarett Doull s Toxicology The Basic Science of Poisons Eighth Edition

The most trusted all-in-one overview of the biomedical and environmental aspects of toxicology--NOW more complete, up-to-date, and in full color The world's leading and most authoritative textbook on poisons has more to offer students,toxicologists, and pharmacologists than ever before. Now in full color, and thoroughly revised, the eighth edition of Casarett & Doull's TOXICOLOGY: The Basic Science of Poisons not only delivers a comprehensive review of the essential components of toxicology, it offers the most up-to-date, revealing, and in-depth look

Casarett Doull s Toxicology The Basic Science of Poisons Eighth Edition

Casarett   Doull s Toxicology  The Basic Science of Poisons  Eighth Edition
  • Author : Louis J. Casarett,John Doull
  • Publisher : McGraw Hill Professional
  • Release : 19 June 2013
GET THIS BOOK Casarett Doull s Toxicology The Basic Science of Poisons Eighth Edition

Casarett and Doull's has set the standard for toxicology reference texts for years, and is the market leading title to this day. It serves the general toxicology market, and is to the field what Goodman and Gilman is to pharmacology. The books are often purchased together, and form a knock-out punch along with our DiPiro textbook; combined, these three titles produce millions of dollars in revenue and more than 100,000 in unit sales. Casarett & Doull's is, in other words, one part