Understanding Cancer from a Systems Biology Point of View

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  • Author : Irina Kareva
  • Publisher : Academic Press
  • Pages : 118 pages
  • ISBN : 012813674X
  • Rating : /5 from reviews
CLICK HERE TO GET THIS BOOK >>>Understanding Cancer from a Systems Biology Point of View

Download or Read online Understanding Cancer from a Systems Biology Point of View full in PDF, ePub and kindle. this book written by Irina Kareva and published by Academic Press which was released on 07 February 2018 with total page 118 pages. We cannot guarantee that Understanding Cancer from a Systems Biology Point of View book is available in the library, click Get Book button and read full online book in your kindle, tablet, IPAD, PC or mobile whenever and wherever You Like. Understanding Cancer from a Systems Biology Point of View: From Observation to Theory and Back starts with a basic question, why do we sometimes observe accelerated metastatic growth after resection of primary tumors? Next, it helps readers understand the systemic nature of cancer and how it affects treatment approaches and decisions. The book puts together aspects of cancer that many readers have most likely never combined, using unfamiliar, novel methods. It is a valuable resource for cancer researchers, cancer biologists, mathematicians and members of the biomedical field who are interested in applying systems biology methodologies for understanding and treating cancer. Explains the systemic nature of cancer and how it affects decisions on treatment Brings a variety of methods together, showing, in detail, the logical approach to finding answers to complex questions Discusses the theoretical underpinnings of cancer as a systemic disease, providing the reader with valuable information on applicable cases

Understanding Cancer from a Systems Biology Point of View

Understanding Cancer from a Systems Biology Point of View
  • Author : Irina Kareva
  • Publisher : Academic Press
  • Release : 07 February 2018
GET THIS BOOK Understanding Cancer from a Systems Biology Point of View

Understanding Cancer from a Systems Biology Point of View: From Observation to Theory and Back starts with a basic question, why do we sometimes observe accelerated metastatic growth after resection of primary tumors? Next, it helps readers understand the systemic nature of cancer and how it affects treatment approaches and decisions. The book puts together aspects of cancer that many readers have most likely never combined, using unfamiliar, novel methods. It is a valuable resource for cancer researchers, cancer biologists,

Systems Biology of Tumor Physiology

Systems Biology of Tumor Physiology
  • Author : David H. Nguyen
  • Publisher : Springer
  • Release : 11 December 2015
GET THIS BOOK Systems Biology of Tumor Physiology

This exciting SpringerBrief presents evidence for new ideas that will challenge several theories of how cancer biology is understood. Cancer biology has undergone several intellectual revolutions in the past 50 years. A mutation-centric view of cancer has given way to the tumor microenvironment view. Reductionistic studies of one gene at a time have given way to systems biology approaches that analyze the whole genome (omics) at the same time. However, this text combines the complex levels studying cancer at the molecular

Modeling Evolution of Heterogeneous Populations

Modeling Evolution of Heterogeneous Populations
  • Author : Irina Kareva,Georgy Karev
  • Publisher : Academic Press
  • Release : 16 October 2019
GET THIS BOOK Modeling Evolution of Heterogeneous Populations

Modeling Evolution of Heterogeneous Populations: Theory and Applications describes, develops and provides applications of a method that allows incorporating population heterogeneity into systems of ordinary and discrete differential equations without significantly increasing system dimensionality. The method additionally allows making use of results of bifurcation analysis performed on simplified homogeneous systems, thereby building on the existing body of tools and knowledge and expanding applicability and predictive power of many mathematical models. Introduces Hidden Keystone Variable (HKV) method, which allows modeling evolution

Automated Reasoning for Systems Biology and Medicine

Automated Reasoning for Systems Biology and Medicine
  • Author : Pietro Liò,Paolo Zuliani
  • Publisher : Springer
  • Release : 11 June 2019
GET THIS BOOK Automated Reasoning for Systems Biology and Medicine

This book presents outstanding contributions in an exciting, new and multidisciplinary research area: the application of formal, automated reasoning techniques to analyse complex models in systems biology and systems medicine. Automated reasoning is a field of computer science devoted to the development of algorithms that yield trustworthy answers, providing a basis of sound logical reasoning. For example, in the semiconductor industry formal verification is instrumental to ensuring that chip designs are free of defects (or “bugs”). Over the past 15 years,

Modeling Evolution of Heterogenous Populations

Modeling Evolution of Heterogenous Populations
  • Author : Irina Kareva,Georgy Karev
  • Publisher : Academic Press
  • Release : 15 September 2019
GET THIS BOOK Modeling Evolution of Heterogenous Populations

Modeling Evolution of Heterogenous Populations: Theory and Applications seeks to address the gap that exists in the science, thus helping biological scientists model the evolution of heterogenous populations and visualize evolutionary trajectories. In a vast majority of conceptual, and often even descriptive mathematical models of population dynamics, whether it be predator-prey type models, spread of infectious diseases, or tumor growth, population homogeneity is the first assumption made. As natural selection and evolution cannot act on any population that is not

Computational Systems Biology of Cancer

Computational Systems Biology of Cancer
  • Author : Emmanuel Barillot,Laurence Calzone,Philippe Hupe,Jean-Philippe Vert,Andrei Zinovyev
  • Publisher : CRC Press
  • Release : 25 August 2012
GET THIS BOOK Computational Systems Biology of Cancer

The future of cancer research and the development of new therapeutic strategies rely on our ability to convert biological and clinical questions into mathematical models—integrating our knowledge of tumour progression mechanisms with the tsunami of information brought by high-throughput technologies such as microarrays and next-generation sequencing. Offering promising insights on how to defeat cancer, the emerging field of systems biology captures the complexity of biological phenomena using mathematical and computational tools. Novel Approaches to Fighting Cancer Drawn from the

Philosophy of Cancer

Philosophy of Cancer
  • Author : Marta Bertolaso
  • Publisher : Springer
  • Release : 24 August 2016
GET THIS BOOK Philosophy of Cancer

Since the 1970s, the origin of cancer is being explored from the point of view of the Somatic Mutation Theory (SMT), focusing on genetic mutations and clonal expansion of somatic cells. As cancer research expanded in several directions, the dominant focus on cells remained steady, but the classes of genes and the kinds of extra-genetic factors that were shown to have causal relevance in the onset of cancer multiplied. The wild heterogeneity of cancer-related mutations and phenotypes, along with the

Systems Biology of Cancer

Systems Biology of Cancer
  • Author : Sam Thiagalingam
  • Publisher : Cambridge University Press
  • Release : 09 April 2015
GET THIS BOOK Systems Biology of Cancer

With over two hundred types of cancer diagnosed to date, researchers the world over have been forced to rapidly update their understanding of the biology of cancer. In fact, only the study of the basic cellular processes, and how these are altered in cancer cells, can ultimately provide a background for rational therapies. Bringing together the state-of-the-art contributions of international experts, Systems Biology of Cancer proposes an ultimate research goal for the whole scientific community: exploiting systems biology to generate

New Challenges for Cancer Systems Biomedicine

New Challenges for Cancer Systems Biomedicine
  • Author : Alberto D'Onofrio,Paola Cerrai,Alberto Gandolfi
  • Publisher : Springer Science & Business Media
  • Release : 25 January 2013
GET THIS BOOK New Challenges for Cancer Systems Biomedicine

The future of oncology seems to lie in Molecular Medicine (MM). MM is a new science based on three pillars. Two of them are evident in its very name and are well known: medical science and molecular biology. However, there is a general unawareness that MM is firmly based on a third, and equally important, pillar: Systems Biomedicine. Currently, this term denotes multilevel, hierarchical models integrating key factors at the molecular, cellular, tissue, through phenotype levels, analyzed to reveal the

Aging and Health A Systems Biology Perspective

Aging and Health   A Systems Biology Perspective
  • Author : A.I. Yashin,S.M. Jazwinski
  • Publisher : Karger Medical and Scientific Publishers
  • Release : 09 October 2014
GET THIS BOOK Aging and Health A Systems Biology Perspective

Aging is a major risk factor for chronic diseases, which in turn can provide information about the aging of a biological system. This publication serves as an introduction to systems biology and its application to biological aging. Key pathways and processes that impinge on aging are reviewed, and how they contribute to health and disease during aging is discussed. The evolution of this situation is analyzed, and the consequences for the study of genetic effects on aging are presented. Epigenetic

Systems Biology in Biotech Pharma

Systems Biology in Biotech   Pharma
  • Author : Ales Prokop,Seth Michelson
  • Publisher : Springer Science & Business Media
  • Release : 05 January 2012
GET THIS BOOK Systems Biology in Biotech Pharma

The US is currently well ahead of the rest of the world in the development and application of SB and its principles especially as they pertain to basic medical research and development. This lead is largely due to its earlier start in the academic arena. However, there is evidence of rapid development in both the UK/EU and Japan, and the gap is narrowing, particularly in the UK. From an industrial point of view, the Pharmaceutical Industry based in the

Systems Biology of Transcription Regulation

Systems Biology of Transcription Regulation
  • Author : Ekaterina Shelest,Edgar Wingender,Joerg Linde
  • Publisher : Frontiers Media SA
  • Release : 09 September 2016
GET THIS BOOK Systems Biology of Transcription Regulation

Transcription regulation is a complex process that can be considered and investigated from different perspectives. Traditionally and due to technical reasons (including the evolution of our understanding of the underlying processes) the main focus of the research was made on the regulation of expression through transcription factors (TFs), the proteins directly binding to DNA. On the other hand, intensive research is going on in the field of chromatin structure, remodeling and its involvement in the regulation. Whatever direction we select,

Molecular Pathology

Molecular Pathology
  • Author : William B. Coleman,Gregory J. Tsongalis
  • Publisher : Academic Press
  • Release : 10 March 2009
GET THIS BOOK Molecular Pathology

Molecular Pathology: The Molecular Basis of Human Disease provides a current and comprehensive view of the molecular basis and mechanisms of human disease. Combining accepted principles with broader theoretical concepts and with contributions from a group of experts, the book looks into disease processes in the context of traditional pathology and their implications for translational molecular medicine. It also discusses concepts in molecular biology and genetics, recent scientific and technological advances in modern pathology, the concept of ""molecular pathogenesis"" of

Integration of Omics Approaches and Systems Biology for Clinical Applications

Integration of Omics Approaches and Systems Biology for Clinical Applications
  • Author : Antonia Vlahou,Harald Mischak,Fulvio Magni,Jerome Zoidakis
  • Publisher : John Wiley & Sons
  • Release : 21 February 2018
GET THIS BOOK Integration of Omics Approaches and Systems Biology for Clinical Applications

Introduces readers to the state of the art of omics platforms and all aspects of omics approaches for clinical applications This book presents different high throughput omics platforms used to analyze tissue, plasma, and urine. The reader is introduced to state of the art analytical approaches (sample preparation and instrumentation) related to proteomics, peptidomics, transcriptomics, and metabolomics. In addition, the book highlights innovative approaches using bioinformatics, urine miRNAs, and MALDI tissue imaging in the context of clinical applications. Particular emphasis