Tumor Microenvironment Regulation of Tumor Expansion

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  • Author : Domenico Ribatti
  • Publisher : Academic Press
  • Pages : 172 pages
  • ISBN : 0128228040
  • Rating : /5 from reviews
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Download or Read online Tumor Microenvironment Regulation of Tumor Expansion full in PDF, ePub and kindle. this book written by Domenico Ribatti and published by Academic Press which was released on 04 April 2021 with total page 172 pages. We cannot guarantee that Tumor Microenvironment Regulation of Tumor Expansion book is available in the library, click Get Book button and read full online book in your kindle, tablet, IPAD, PC or mobile whenever and wherever You Like. Tumor Microenvironment Regulation of Tumor Expansion is a practical guide to understand and perform research on tumor microenvironments, and to support related clinical decisions. Tumor progression is linked to an imbalance between positive and negative regulators, and mainly depends on the release of specific growth factors by inflammatory or neoplastic cells. Inflammatory infiltrate contributes to tumor progression and the metastatic process, and there are many reports of associations between tumor inflammatory infiltrate, progression, and prognosis. Understanding different contexts of organs is a key factor in improving treatment outcome, especially in new therapeutic treatments targeting components of the tumor microenvironment. This book is a valuable resource for cancer researchers, clinicians, graduate students, and scientists in many biomedical fields who are interested in the complex relationship between the tumor microenvironment and its context in specific organs. Provides a holistic approach to understanding the crucial role of the tumor microenvironment in tumor progression Encompasses the basic knowledge necessary to understand and undertake further studies related to tumor microenvironments Discusses new therapeutic approaches developed to control tumor progression by targeting different components of the tumor microenvironment

Tumor Microenvironment Regulation of Tumor Expansion

Tumor Microenvironment Regulation of Tumor Expansion
  • Author : Domenico Ribatti
  • Publisher : Academic Press
  • Release : 04 April 2021
GET THIS BOOK Tumor Microenvironment Regulation of Tumor Expansion

Tumor Microenvironment Regulation of Tumor Expansion is a practical guide to understand and perform research on tumor microenvironments, and to support related clinical decisions. Tumor progression is linked to an imbalance between positive and negative regulators, and mainly depends on the release of specific growth factors by inflammatory or neoplastic cells. Inflammatory infiltrate contributes to tumor progression and the metastatic process, and there are many reports of associations between tumor inflammatory infiltrate, progression, and prognosis. Understanding different contexts of organs

Tumor Microenvironment

Tumor Microenvironment
  • Author : Alexander Birbrair
  • Publisher : Springer Nature
  • Release : 06 February 2020
GET THIS BOOK Tumor Microenvironment

Revealing essential roles of the tumor microenvironment in cancer progression, this book provides a comprehensive overview of the latest research on how different signaling pathways are important in the tumor microenvironment. Multiple signaling pathways are covered, including S1P, neuregulin, Notch, erythropoietin, Rho-ROCK, mTOR, and more. Taken alongside its companion volumes, these books update us on what we know about various aspects of the tumor microenvironment as well as future directions. Tumor Microenvironment: Signaling Pathways – Part A is essential reading

Interaction between Hyaluronic Acid and Its Receptors CD44 RHAMM Regulates the Activity of Inflammation and Cancer

Interaction between Hyaluronic Acid and Its Receptors  CD44  RHAMM  Regulates the Activity of Inflammation and Cancer
  • Author : David Naor
  • Publisher : Frontiers Media SA
  • Release : 18 July 2016
GET THIS BOOK Interaction between Hyaluronic Acid and Its Receptors CD44 RHAMM Regulates the Activity of Inflammation and Cancer

The biological outcome of Hyaluronan (also hyaluronic acid, abbreviated HA) interaction with its CD44 or RHAMM receptors recently attracted much attention within the scientific community owing to a Nature article by Tian X et al. (Nature 2013; 499:346-9). The article described a life span exceeding 30 years in naked mole rats, whereas the maximal lifespan of mice, to which the naked mole rat is related, is only 4 years. This observation is accompanied by the finding that the naked mole rat, in contrast

Cancer Associated Thrombosis

Cancer Associated Thrombosis
  • Author : Alok A. Khorana,Charles W. Francis
  • Publisher : CRC Press
  • Release : 26 September 2007
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Showcasing the expertise of top-tier specialists who contributed to the newly released guidelines for the care of thrombosis in cancer patients, this exciting guide was written and edited by members of the American Society of Clinical Oncology panel, (ASCO), on the prevention and treatment of cancer-associated thrombosis, among others, and provides

Innate and Adaptive Immunity in the Tumor Microenvironment

Innate and Adaptive Immunity in the Tumor Microenvironment
  • Author : Eitan Yefenof
  • Publisher : Springer Science & Business Media
  • Release : 20 December 2007
GET THIS BOOK Innate and Adaptive Immunity in the Tumor Microenvironment

Traditionally, the interplay between cancer cells and host immunity has been studied systemically. Recent studies, however, indicate that the tumor microenvironment is unique in providing both supportive and inhibitory factors that determine the fate of the tumor and its host. This volume compiles reviews on innate and adaptive immune responses at the tumor microenvironment with emphasis on positive and negative outcomes that affect the progression of the disease.

Cancer Genome and Tumor Microenvironment

Cancer Genome and Tumor Microenvironment
  • Author : Andrei Thomas-Tikhonenko
  • Publisher : Springer Science & Business Media
  • Release : 23 January 2010
GET THIS BOOK Cancer Genome and Tumor Microenvironment

Oncogenes and tumor suppressor genes had been traditionally studied in the context of cell proliferation, differentiation, senescence, and survival, four relatively cell-autonomous processes. Consequently, in the late ’80s-early ’90s, neoplastic growth was described largely as an imbalance between net cell accumulation and loss, brought about through mutations in cancer genes. In the last ten years, a more holistic understanding of cancer has slowly emerged, stressing the importance of interactions between neoplastic and various stromal components: extracellular matrix, basement membranes, fibroblasts,

Cancer Immunology and Immunotherapy

Cancer Immunology and Immunotherapy
  • Author : Mansoor M. Amiji,Lara Scheherazade Milane
  • Publisher : Academic Press
  • Release : 18 August 2021
GET THIS BOOK Cancer Immunology and Immunotherapy

Delivery Technologies for Immuno-Oncology: Volume 1: Delivery Strategies and Engineering Technologies in Cancer Immunotherapy examines the challenges of delivering immuno-oncology therapies. Immuno-oncology (IO) is a growing field of medicine at the interface of immunology and cancer biology leading to development of novel therapeutic approaches, such as chimeric antigen receptor T-cell (CAR-T) and immune checkpoint blockade antibodies, that are clinically approved approaches for cancer therapy. Although currently approved IO approaches have shown tremendous promise for select types of cancers, broad application of

Sirtuin Biology in Cancer and Metabolic Disease

Sirtuin Biology in Cancer and Metabolic Disease
  • Author : Kenneth Maiese
  • Publisher : Elsevier
  • Release : 20 February 2021
GET THIS BOOK Sirtuin Biology in Cancer and Metabolic Disease

Sirtuin Biology in Cancer and Metabolic Disease: Cellular Pathways for Clinical Discovery offers a compelling and thought-provoking perspective for the examination of the intriguing biology of sirtuins that ties cancer and metabolic disease together and provides a critical platform for the development of sirtuin-based novel therapeutic strategies to effectively treat cancer and metabolic disorders with precision in order to minimize any potentially detrimental clinical outcomes. An exciting prospect for the development of innovative therapeutics for cancer and metabolic disorders involves

The Tumor Microenvironment

The Tumor Microenvironment
  • Author : Rebecca G. Bagley
  • Publisher : Springer Science & Business Media
  • Release : 02 September 2010
GET THIS BOOK The Tumor Microenvironment

The fact that tumors are composed of both tumor cells and host cells has long been known. These tumor-associated cells include vascular endothelial cells and pe- cytes, as well as inflammatory cells such as neutrophils, monocytes, macrophages, mast cells and eosinophils, and lymphocytes. The tumor cells also interact with stromal cells and with elements of the tissue extracellular matrix. What has been less appreciated is the role that these cells could have in modulating the growth, invasion, and metastasis of

Translational Research in Breast Cancer

Translational Research in Breast Cancer
  • Author : Erwei Song,Hai Hu
  • Publisher : Springer
  • Release : 28 December 2017
GET THIS BOOK Translational Research in Breast Cancer

This book offers a comprehensive introduction to translational efforts in breast cancer, addressing the latest approaches to precision medicine based on the current state of understanding of breast cancer. With the latest developments in breast cancer research, our understanding of the genomic changes and the oncogenic signaling cascade of breast cancer has made considerable strides. Further, the immuno-environment has been demonstrated as the barrier to clinical cancer. In addition, major advances in cancer biology, immunology, genomics and metabolism have broken

Immunotherapy of Cancer

Immunotherapy of Cancer
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 29 July 2015
GET THIS BOOK Immunotherapy of Cancer

Immunotherapy of Cancer provides information on cancer research related to inflammation and immunity, containing outstanding reviews by experts in the field. It is suitable for researchers and students who have an interest in cancer immunobiology. Provides information on cancer research, including outstanding and original reviews Covers the current progress and emerging concepts in cancer inflammation, immunology, and immunotherapy Suitable for researchers and students studying, and interested in, the field of immunotherapy for cancer Ideal for those studying cancer inflammation, tumor

Tumor Microenvironment and Myelomonocytic Cells

Tumor Microenvironment and Myelomonocytic Cells
  • Author : Subhra Biswas
  • Publisher : BoD – Books on Demand
  • Release : 30 March 2012
GET THIS BOOK Tumor Microenvironment and Myelomonocytic Cells

Tumor microenvironment represents an extremely dynamic niche shaped by the interplay of different cell types (e.g. tumor cells, stromal cells), their soluble products (e.g.cytokines, chemokines and growth factors) and varied physico-chemical conditions (e.g low oxygen concentration or hypoxia). Recent studies have identified myelomonocytic cells as key players in regulating the tumor microenvironment and hence, tumor progression in a variety of cancers. In view of these findings, the present book attemps to provide a comprehensive account of

Cancer Immunotherapy

Cancer Immunotherapy
  • Author : George C. Prendergast,Elizabeth M. Jaffee
  • Publisher : Academic Press
  • Release : 04 June 2013
GET THIS BOOK Cancer Immunotherapy

There has been major growth in understanding immune suppression mechanisms and its relationship to cancer progression and therapy. This book highlights emerging new principles of immune suppression that drive cancer, and it offers radically new ideas about how therapy can be improved by attacking these principles. Following work that firmly establishes immune escape as an essential trait of cancer, recent studies have now defined specific mechanisms of tumor immune suppression. It also demonstrates how attacking tumors with molecular targeted therapeutics

Metabolism of Cancer Cells and Immune Cells in the Tumor Microenvironment

Metabolism of Cancer Cells and Immune Cells in the Tumor Microenvironment
  • Author : Yongsheng Li,Bo Zhu
  • Publisher : Frontiers Media SA
  • Release : 20 March 2019
GET THIS BOOK Metabolism of Cancer Cells and Immune Cells in the Tumor Microenvironment

Metabolism of glucose, lipids, amino acids, and nucleotides represents the fundamental capability of host to utilize distinct nutrients and energy to support diverse function of different cell lineages. Cancer cells undergo the Warburg Effect to adapt to the microenvironment composed by stromal cells and immune cells. The crosstalk among cancer cells and immune cells orchestrate tumor progression. In the tumor microenvironment, immune cells also show metabolic reprogramming. For example, naive or memory T cells switch from the oxidation of fatty