Translational Glycobiology in Human Health and Disease

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  • Author : Michelle Kilcoyne
  • Publisher : Academic Press
  • Pages : 480 pages
  • ISBN : 9780128196557
  • Rating : /5 from reviews
CLICK HERE TO GET THIS BOOK >>>Translational Glycobiology in Human Health and Disease

Download or Read online Translational Glycobiology in Human Health and Disease full in PDF, ePub and kindle. this book written by Michelle Kilcoyne and published by Academic Press which was released on 15 November 2020 with total page 480 pages. We cannot guarantee that Translational Glycobiology in Human Health and Disease book is available in the library, click Get Book button and read full online book in your kindle, tablet, IPAD, PC or mobile whenever and wherever You Like. Along with nucleic acids, proteins, and lipids, carbohydrates stand as one of four main components of cellular architecture. However, glycobiology (or carbohydrate bioscience) is little understood by non-experts, partly because carbohydrates are a complex, diverse class of molecules structurally and functionally. In recent years, advances in computational analytics (glycomics) have allowed us to better interpret and realize the importance of glycobiology in human health and disease, and glycans and their associated processes have been shown to play a significant role across a variety of disease types. As the biomedical sciences continue to adopt multi-omic and precision medicine approaches, a greater understanding of glycobiology is essential for maintaining healthy physiology and advancing disease treatment. Translational Glycobiology in Human Health and Disease offers a deep examination of glycobiology for experts and non-experts alike in areas ranging from the role of glycobiology in chronic and infectious diseases to advances in technologies for higher throughput analysis and diagnosis. While keeping human health in the forefront, this book integrates a thorough discussion of glycobiology fundamentals with its growing areas of application and societal impact. With emphasis throughout on the interdisciplinary nature of glycosciences, this book also features perspectives from the health, computational (glycoanalytics), materials, biopharmaceutical, and diagnostic sciences. Disease and speciality areas addressed include gycoimmunology, neuroglycobiology, commensal glycobiology, gut health, regenerative medicine and glycobiology, glycobiology and cancer, congenital disorders of glycosylation, infectious disease glycobiology, and parasite glycobiology. Computational approaches discussed, supporting the advance of new research, include advanced glycoanalytics, glycomics microarrays, glycoengineering, and glycol systems biology. Additionally, authors consider impact areas for society and public health, such as glycobiology and entrepreneurship, policy and regulatory requirements for glycosylation, future research, and translation to new diagnostics and drug discovery. Provides a deep, foundational overview of glycoscience and its translational potential, highlighting glycobiology's growing role in human health and disease study Examines a broad range of relevant disease areas and applications of glycobiology in policy and public health Features chapter contributions from leading, international experts in the field, fully integrating perspectives from the health, computational, materials, biopharmaceutical, and diagnostic sciencess

Translational Glycobiology in Human Health and Disease

Translational Glycobiology in Human Health and Disease
  • Author : Michelle Kilcoyne,Lokesh Joshi
  • Publisher : Academic Press
  • Release : 15 November 2020
GET THIS BOOK Translational Glycobiology in Human Health and Disease

Along with nucleic acids, proteins, and lipids, carbohydrates stand as one of four main components of cellular architecture. However, glycobiology (or carbohydrate bioscience) is little understood by non-experts, partly because carbohydrates are a complex, diverse class of molecules structurally and functionally. In recent years, advances in computational analytics (glycomics) have allowed us to better interpret and realize the importance of glycobiology in human health and disease, and glycans and their associated processes have been shown to play a significant role

Proteases in Health and Disease

Proteases in Health and Disease
  • Author : Enrico Di Cera
  • Publisher : Academic Press
  • Release : 24 January 2011
GET THIS BOOK Proteases in Health and Disease

Proteases occur naturally in all organisms. They are enzymes that are involved in many physiological reactions such as digestion of food and blood clotting. This volume reviews their role in health and disease and presents the latest research and developments. Discusses new discoveries, approaches, and ideas Contributions from leading scholars and industry experts Reference guide for researchers involved in molecular biology and related fields

Novel Methods and Pathways in Cancer Glycobiology Research

Novel Methods and Pathways in Cancer Glycobiology Research
  • Author : Anonim
  • Publisher : Elsevier
  • Release : 01 February 2023
GET THIS BOOK Novel Methods and Pathways in Cancer Glycobiology Research

Cancer glycobiology is a blazing hot area of cancer research with aberrant post-translational glycosylations on lipids and proteins considered critical for cancer development and metastasis. The NIH/NCI Alliance of Glycobiologists for Cancer Research is a consortium of (10) tumor glycobiology laboratories funded to investigate how cancer-associated glycans (CAG) impact the development and metastasis of cancer. The hope of this momentous effort is to discover CAGs for use as novel biomarkers to detect early-stage cancer or its aggressive behavior or, alternatively,

Gangliosides in Health and Disease

Gangliosides in Health and Disease
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 25 April 2018
GET THIS BOOK Gangliosides in Health and Disease

Gangliosides in Health and Disease, Volume 156, presents the latest information on Gangliosides, a class of glycolipids that are found on all vertebrate cell surfaces, and are particularly abundant in the brain. Individual chapters in this new volume cover Gangliosides as Toxin Receptors, Gangliosides in Cancer Cell Signaling, Gangliosides in inflammation and neurodegeneration, Gangliosides as functional galectin receptors, Gangliosides in signal transduction, Gangliosides in brain tumor immunology, and Gangliosides in axon regeneration and stability, amongst other related topics. This book brings

Progress in Molecular Biology and Translational Science

Progress in Molecular Biology and Translational Science
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 22 March 2019
GET THIS BOOK Progress in Molecular Biology and Translational Science

Glycans and Glycosaminoglycans as Clinical Biomarkers and Therapeutics - Part A, Volume 162 in the Progress in Molecular Biology and Translational Science series provides informative monographs on a variety of research topics related to Glycans and glycosaminoglycans as clinical biomarkers and therapeutics. Topics in this update include Glycan-based Biomarkers for Diagnosis of Cancers and Other Diseases: Past, Present and Future, Desialylation in Diseases and its Application in Diagnostic and Therapeutic Development, Proteoglycans as Miscommunication Biomarkers for Cancer Diagnosis, Fucosylation in Cancer

Sialic Acids and Sialoglycoconjugates in the Biology of Life Health and Disease

Sialic Acids and Sialoglycoconjugates in the Biology of Life  Health and Disease
  • Author : Shyamasree Ghosh
  • Publisher : Academic Press
  • Release : 08 January 2020
GET THIS BOOK Sialic Acids and Sialoglycoconjugates in the Biology of Life Health and Disease

Sialic Acids and Sialoglycoconjugates in the Biology of Life, Health and Disease enables the reader to understand the role of sialylation as a post translational modification. The book provides insights on the latest knowledge in the field of sialoglycobiology. Sialic acids as terminal residues of oligosaccharide chains play crucial roles in several cellular recognition events. Synthesized post translationally, they play an important role in recognition, signaling, immunological response and cell-cell interaction. Improper sialylations have been associated with several diseases including

Protein Glycosylation

Protein Glycosylation
  • Author : Roslyn M. Bill,Leigh Revers,Iain B.H. Wilson
  • Publisher : Springer Science & Business Media
  • Release : 30 November 1998
GET THIS BOOK Protein Glycosylation

Protein Glycosylation provides clear, up-to-date, and integrated coverage of key topics in this field. Particular emphasis is placed on the biosynthetic pathways that result in a wide variety of identified protein-bound oligosaccharides. Protein Glycosylation begins with an overview of the chemical structures of mono- and oligosaccharides, to provide a scientific basis for the later chapters. The book includes discussions on the purification, function, and enzyme kinetics of selected glycosidases and glycotransferases, as well as a review of the roles of

Genome Plasticity in Health and Disease

Genome Plasticity in Health and Disease
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 08 April 2020
GET THIS BOOK Genome Plasticity in Health and Disease

Genome Plasticity in Health and Disease provides a fully up-to-date overview on genome plasticity and its role in human physiology and disease. Following an introduction to the field, a diverse range of chapters cover genomic and epigenomic analysis and the use of model organisms and genomic databases in studies. Specific molecular and biochemical mechanisms of genome plasticity are examined, including somatic variants, De Novo variants, founder variations, isolated populations dynamics, copy-number variations, mobile elements, DNA methylation, histone modifications, transcription factors,

The Role of Glycans in Immune Cell Functions

The Role of Glycans in Immune Cell Functions
  • Author : Jasmeen S. Merzaban,Monica M. Burdick,Charles J. Dimitroff
  • Publisher : Frontiers Media SA
  • Release : 26 May 2020
GET THIS BOOK The Role of Glycans in Immune Cell Functions

Glycans represent a major constituency of post-translational modifications that occur on most, if not all, proteins. Whether on mammalian or invertebrate cell surfaces, they exist as sugar chain moieties designed from the exquisite and coordinated activity of cell-specific glycosylation. Some of the more common glycan structures are linked to cell surface polypeptides via an asparagine (N)-linked residue or a serine/threonine (O)-linked residue, along with a notable contingent found linked to ceramides in the lipid bilayer known as

Proceedings of 3rd Glycobiology World Congress 2017

Proceedings of 3rd Glycobiology World Congress 2017
  • Author : ConferenceSeries
  • Publisher : ConferenceSeries
  • Release : 07 June 2023
GET THIS BOOK Proceedings of 3rd Glycobiology World Congress 2017

June 26-28, 2017 London, UK Key Topics : Glycoprotein Technologies, Glyco Bioinformatics, Glycans in Drug Design, Glyco Immunology, Glyco Biomarkers, Glycobiology and Biotechnology, Glycans in Diseases and Therapeutics, Glycobiology in Personalized Medicine, Glycans in Genetic Disorders, Glycobiology and Structural Biology, Glyco Proteomics, Glycomics and Metabolomics, Mass Spectrometry in Proteome Research, Glycobiology, Genomics and Computational Systems Biology, Glycobiochemistry,

Microbiota in health and disease from pregnancy to childhood

Microbiota in health and disease  from pregnancy to childhood
  • Author : Pamela D. Browne,Eric Claassen,Michael D. Cabana
  • Publisher : Wageningen Academic Publishers
  • Release : 20 July 2017
GET THIS BOOK Microbiota in health and disease from pregnancy to childhood

This book offers a state-of-the-art overview of the vital relationship between human microbiota and infant and child health. Renowned clinical-experimental experts in this field discuss the development of microbiota during early life and review the environmental inputs that affect the developing infant’s gut microbiota, such as early diet and (postnatal) medical interventions. They further describe the interplay between gut microbiota and functional systems of the body, from the immune system to the central nervous system. The book discusses a

Galectins in Cancer and Translational Medicine

Galectins in Cancer and Translational Medicine
  • Author : Armando Bartolazzi
  • Publisher : MDPI
  • Release : 29 November 2018
GET THIS BOOK Galectins in Cancer and Translational Medicine

In the post-genomic era, many efforts have been devoted to better understanding the biological information encoded by the cell "glycome" in normal and pathologic conditions. The glycan signature of human cells plays a pivotal role in regulating fundamental biological processes, which are critical for cell physiology and for cancer as well. Galectins (also worded S-type lectins) are an evolutionarily conserved family of endogenous lectins, which bind carbohydrates with high specificity. These molecules, which can be found both intracellularly and in

Lung Inflammation in Health and Disease Volume I

Lung Inflammation in Health and Disease  Volume I
  • Author : Yong-Xiao Wang
  • Publisher : Springer Nature
  • Release : 31 March 2021
GET THIS BOOK Lung Inflammation in Health and Disease Volume I

Respiratory diseases are leading causes of death and disability globally, with about 65 million people suffering from COPD, and 334 million from asthma, the most common chronic disease. Each year, tens of millions of people develop and can die from from respiratory infections such as pneumonia and TB. Systemic inflammation may induce and exacerbate local inflammatory diseases in the lungs, and local inflammation can in turn cause systemic inflammation. There is increasing evidence of the coexistence of systemic and local inflammation in

The Role of Glycosylation in Health and Disease

The Role of Glycosylation in Health and Disease
  • Author : Gordan Lauc,Irena Trbojević-Akmačić
  • Publisher : Springer Nature
  • Release : 08 September 2021
GET THIS BOOK The Role of Glycosylation in Health and Disease

Glycobiology is an emerging field of studying glycans (sugars) and glycoconjugates that are essentially involved in almost all biological processes, from fine-tuning glycoprotein function to protein-protein interactions, signaling, immune response, host-pathogen interactions, etc. However, due to structural complexity of glycans and analytical challenges this exciting field was lagging behind other areas of biology. With technological advancements growing number of glycans’ functions are being discovered and the study of glycans is becoming a cutting-edge discipline in basic and clinical research. Despite

Co and Post Translational Modifications of Therapeutic Antibodies and Proteins

Co  and Post Translational Modifications of Therapeutic Antibodies and Proteins
  • Author : T. Shantha Raju
  • Publisher : John Wiley & Sons
  • Release : 15 March 2019
GET THIS BOOK Co and Post Translational Modifications of Therapeutic Antibodies and Proteins

A Comprehensive Guide to Crucial Attributes of Therapeutic Proteins in Biological Pharmaceuticals With this book, Dr. Raju offers a valuable resource for professionals involved in research and development of biopharmaceutical and biosimilar drugs. This is a highly relevant work, as medical practitioners have increasingly turned to biopharmaceutical medicines in their search for safe and reliable treatments for complex diseases, while pharmaceutical researchers seek to expand the availability of biopharmaceuticals and create more affordable biosimilar alternatives. Readers receive a thorough overview