Translating Regenerative Medicine to the Clinic

• Author : Jeffrey Laurence,Pedro Baptista,Anthony Atala
• Publisher : Academic Press
• Release : 18 November 2015

Translating Regenerative Medicine to the Clinic reviews the current methodological tools and experimental approaches used by leading translational researchers, discussing the uses of regenerative medicine for different disease treatment areas, including cardiovascular disease, muscle regeneration, and regeneration of the bone and skin. Pedagogically, the book concentrates on the latest knowledge, laboratory techniques, and experimental approaches used by translational research leaders in this field. It promotes cross-disciplinary communication between the sub-specialties of medicine, but remains unified in theme by emphasizing recent

• Author : Jeffrey Laurence,Michael Franklin
• Publisher : Academic Press
• Release : 14 November 2014

Translating Gene Therapy to the Clinic, edited by Dr. Jeffrey Laurence and Michael Franklin, follows the recent, much-lauded special issue of Translational Research in emphasizing clinical milestones and critical barriers to further progress in the clinic. This comprehensive text provides a background for understanding the techniques involved in human gene therapy trials, and expands upon the disease-specific situations in which these new approaches currently have the greatest therapeutic application or potential, and those areas most in need of future research.

• Author : Pawanbir Singh
• Publisher : Unknown
• Release : 21 March 2023

The primary aim of the thesis is to contribute to demonstrating how established and emerging science in the regenerative medicine (RM) domain can be translated into profitable commercial practice, and generate clinically- and cost-effective therapies. It achieves this by exploring and assessing underlying economics, including investment readiness and economic assessment, exploring regulatory and reimbursement frameworks, developing stem cell culture systems and assessing fit with clinical practice. The thesis is the first public domain wide-ranging analysis of business trends in the

• Author : Robert Chunhua Zhao
• Publisher : Springer Science & Business Media
• Release : 05 June 2013

Mesenchymal stem cells (MSCs), a type of adult stem cells, have attracted the attention of scientists and physicians alike due to their unique biological properties and potential for disease treatment. As stem cell research is complex and progressing rapidly, it is important that the experts in this field share their views and perspectives. This book, co-edited by leading global researchers, is divided into three major sections and covers a broad range of topics concerning MSCs during their transition from benchside

• Author : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Sciences Policy,Forum on Regenerative Medicine
• Publisher : National Academies Press
• Release : 19 July 2019

The emerging multidisciplinary field of regenerative engineering is devoted to the repair, regeneration, and replacement of damaged tissues or organs in the body. To accomplish this it uses a combination of principles and technologies from disciplines such as advanced materials science, developmental and stem cell biology, immunology, physics, and clinical translation. The term "regenerative engineering" reflects a new understanding of the use of tissue engineering for regeneration and also the growing number of research and product development efforts that incorporate

• Author : Robert Chunhua Zhao
• Publisher : Springer
• Release : 14 September 2015

This book provides a comprehensive review of the properties of various stem cell types, the mechanisms of their behaviors and their potential clinical application. Stem cells have a great capacity of self-renewal and differentiation. They represent new paradigms for disease treatment in the field of regenerative medicine since the day they were discovered. As stem cell research is complicated and making progress rapidly, it is important to have expertise in this field to share their views and perspectives. This book

• Author : Gustav Steinhoff
• Publisher : Springer
• Release : 07 June 2016

​Regenerative medicine is the main field of groundbreaking medical development and therapy using knowledge from developmental and stem cell biology as well as advanced molecular and cellular techniques. This collection of volumes on Regenerative Medicine: From Protocol to Patient, aims to explain the scientific knowledge and emerging technology as well as the clinical application in different organ systems and diseases. International leading experts from all over the world describe the latest scientific and clinical knowledge of the field of regenerative

• Author : Karen J. Maschke,Michael K. Gusmano
• Publisher : ABC-CLIO
• Release : 14 September 2018

This book analyzes policy fights about what counts as good evidence of safety and effectiveness when it comes to new health care technologies in the United States and what political decisions mean for patients and doctors. • Helps readers to understand the political, economic, and ideological dimensions of disputes about health technology assessment and the implications of various policy approaches for patients and the health care system • Includes discussion of disputes related to hot topics such as stem cell therapies, mammography

• Author : Kwok Fai So,Xiao-Ming Xu
• Publisher : Academic Press
• Release : 03 February 2015

Neural Regeneration provides an overview of cutting-edge knowledge on a broad spectrum of neural regeneration, including: Neural regeneration in lower vertebrates Neural regeneration in the peripheral nervous system Neural regeneration in the central nervous system Transplantation-mediated neural regeneration Clinical and translational research on neural regeneration The contributors to this book are experts in their fields and work at distinguished institutions in the United States, Canada, Australia, and China. Nervous system injuries, including peripheral nerve injuries, brain and spinal cord injuries,

• Author : Stewart Sell
• Publisher : Springer Science & Business Media
• Release : 16 August 2013

This book discusses critical areas of progress in stem cell research, including the most recent research and applications of pluripotent embryonic cells, induced pluripotent cells, oligopotent tissue stem cells and cancer stem cells. The text covers basic knowledge of stem cell biology, stem cell ethics, development of techniques for applying stem cell therapy, the technology of obtaining appropriate cells for transplantation as well as the role of stem cells in cancer and how therapy may be directed to cancer stem

• Author : Eric G. Schmuck,Peiman Hematti,Amish N. Raval
• Publisher : Springer
• Release : 20 September 2018

This book on cardiac extracellular matrix (ECM) features three sections, Fundamental Science, Pre-Clinical and Translational Science, and Clinical Applications. In the Fundamental Science section, we will cover the spectrum of basic ECM science from ECM’s role in development, biomechanical properties, cardiac ECM influence of cardiomyocyte biology, pathophysiology of ECM in heart disease, and ECM in tissue engineering. Section two, Preclinical and Translational Science, will discuss cardiac ECM technologies in the clinical pipeline including approaches to ECM as a therapeutic,

• Author : Yasser El Miedany
• Publisher : Springer Nature
• Release : 18 September 2022

The book examines recent developments in regenerative medicine and the use of musculoskeletal ultrasound. Musculoskeletal regeneration has become a prominent research topic, no doubt due to the sociological and economic pressures imposed by the current ageing population. The ever expanding role of regenerative medicine and the identification as well as characterization of stem cells have introduced a major paradigm shift in the field of musculoskeletal and sports medicine as well as orthopaedic surgery. Whereas in the past, diseased tissue was

• Author : Anthony Atala,Julie Allickson
• Publisher : Academic Press
• Release : 01 December 2014

Translational Regenerative Medicine is a reference book that outlines the life cycle for effective implementation of discoveries in the dynamic field of regenerative medicine. By addressing science, technology, development, regulatory, manufacturing, intellectual property, investment, financial, and clinical aspects of the field, this work takes a holistic look at the translation of science and disseminates knowledge for practical use of regenerative medicine tools, therapeutics, and diagnostics. Incorporating contributions from leaders in the fields of translational science across academia, industry, and government,

• Author : Alain A. Vertes,Nasib Qureshi,Arnold I. Caplan,Lee E. Babiss
• Publisher : John Wiley & Sons
• Release : 14 September 2015

This book is a unique guide to emerging stem cell technologies and the opportunities for their commercialisation. It provides in-depth analyses of the science, business, legal, and financing fundamentals of stem cell technologies, offering a holistic assessment of this emerging and dynamic segment of the field of regenerative medicine. • Reviews the very latest advances in the technology and business of stem cells used for therapy, research, and diagnostics • Identifies key challenges to the commercialisation of stem cell technology and avenues

• Author : Elisa López-Dolado,María Concepción Serrano
• Publisher : Springer Nature
• Release : 25 March 2022

This book describes past and present advances in engineering materials for neural applications, with special emphasis on their usefulness for traumatic brain and spinal cord injuries. The book presents major physio-pathological features of traumatic injuries at the brain and spinal cord as examples of diseases hampering the central nervous tissue. By incorporating knowledge from the perspective of experts with diverse backgrounds, this book gives insight into the understanding of these multifaceted pathologies and the materials science approaches that aim to