Therapeutic Oligonucleotides

Produk Detail:
  • Author : John Goodchild
  • Publisher : Humana Press
  • Pages : 340 pages
  • ISBN : 9781493958221
  • Rating : /5 from reviews
CLICK HERE TO GET THIS BOOK >>>Therapeutic Oligonucleotides

Download or Read online Therapeutic Oligonucleotides full in PDF, ePub and kindle. this book written by John Goodchild and published by Humana Press which was released on 23 August 2016 with total page 340 pages. We cannot guarantee that Therapeutic Oligonucleotides book is available in the library, click Get Book button and read full online book in your kindle, tablet, IPAD, PC or mobile whenever and wherever You Like. The field of oligonucleotide therapeutics research is ripe with the prospect of new discoveries. In Therapeutic Oligonucleotides: Methods and Protocols, a selection of established and emerging methods for the application of oligonucleotides as therapeutics are presented, all providing the tools needed to inspire great changes in the field. Divided into twenty-one chapters, this detailed volume meticulously describes vital protocols for optimizing and improving cell uptake, such as photochemical internalization, modified cell penetrating peptides, antibody conjugates, and nanoparticles. Other chapters address quantitation of RNA therapeutics in cells, assaying gene knockdown, selecting the best target site and synthesis of various modified oligonucleotides. Written in the successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Therapeutic Oligonucleotides: Methods and Protocols serves as a timely resource for both professionals and novices pursuing research in this exciting and pioneering field.

Therapeutic Oligonucleotides

Therapeutic Oligonucleotides
  • Author : John Goodchild
  • Publisher : Humana Press
  • Release : 23 August 2016
GET THIS BOOK Therapeutic Oligonucleotides

The field of oligonucleotide therapeutics research is ripe with the prospect of new discoveries. In Therapeutic Oligonucleotides: Methods and Protocols, a selection of established and emerging methods for the application of oligonucleotides as therapeutics are presented, all providing the tools needed to inspire great changes in the field. Divided into twenty-one chapters, this detailed volume meticulously describes vital protocols for optimizing and improving cell uptake, such as photochemical internalization, modified cell penetrating peptides, antibody conjugates, and nanoparticles. Other chapters address

Therapeutic Oligonucleotides

Therapeutic Oligonucleotides
  • Author : Jens Kurreck
  • Publisher : Royal Society of Chemistry
  • Release : 22 April 2008
GET THIS BOOK Therapeutic Oligonucleotides

This book provides a comprehensive overview of the development of therapeutic oligonucleotides for therapeutic applications, touching on a number of additional oligonucleotides including a number of small interfering RNAs currently in various phases of clinical development. Written by leading expert scientists from both academia and leading biotechnical companies, the authors provide a compelling update on current status of RNA interference with emphasis on fascinating topics including oligonucleotides: antisense oligonucleotides, ribozymes, siRNAs, decoy oligonucleotides and aptamers. This exceptional work will be

Synthesis of Therapeutic Oligonucleotides

Synthesis of Therapeutic Oligonucleotides
  • Author : Satoshi Obika,Mitsuo Sekine
  • Publisher : Springer
  • Release : 08 December 2018
GET THIS BOOK Synthesis of Therapeutic Oligonucleotides

This book presents the latest knowledge on a broad range of topics relating to the synthesis of natural and artificial oligonucleotides with therapeutic potential. Nucleic acid-based therapeutics are attracting much attention, and numerous therapeutic oligonucleotides, such as antisense oligonucleotides, siRNAs, splice-switching oligonucleotides, and nucleic acid aptamers, are being evaluated in clinical trials for the treatment of a variety of diseases. Synthesis of Therapeutic Oligonucleotides covers a broad range of topics in the field that are of high relevance to researchers,

Therapeutic Oligonucleotides

Therapeutic Oligonucleotides
  • Author : Yoon S. Cho-Chung,Alan M. Gewirtz,Cy A. Stein,National Institutes of Health (U.S.). Therapeutic Oligonucleotide Interest Group
  • Publisher : Unknown
  • Release : 23 July 2021
GET THIS BOOK Therapeutic Oligonucleotides

This work is concerned with various aspects of oligonucleotides including triplex DNA, transcription factor decoy, antisense DNA/RNA, ribozymes, PNA, 2',5'-oligoadenylates, RNAi, and CpG immune-stimulating oligomers, diagnostic oligonucleotide chips (DNA chips), and gene therapy vectors.

Therapeutic Oligonucleotides

Therapeutic Oligonucleotides
  • Author : Yoon S. Cho-Chung,Alan M. Gewirtz,Cy A. Stein,National Institutes of Health (U.S.). Therapeutic Oligonucleotide Interest Group
  • Publisher : Unknown
  • Release : 23 July 2021
GET THIS BOOK Therapeutic Oligonucleotides

This work is concerned with various aspects of oligonucleotides including triplex DNA, transcription factor decoy, antisense DNA/RNA, ribozymes, PNA, 2',5'-oligoadenylates, RNAi, and CpG immune-stimulating oligomers, diagnostic oligonucleotide chips (DNA chips), and gene therapy vectors.

Therapeutic Oligonucleotides

Therapeutic Oligonucleotides
  • Author : Yoon S. Cho-Chung,Alan M. Gewirtz,Cy A. Stein
  • Publisher : Unknown
  • Release : 23 July 2021
GET THIS BOOK Therapeutic Oligonucleotides

Explores the potential for the development of therapeutic oligonucleotides into clinical medicines and their use as basic research tools, which is the proceedings of the 7th NIH Symposium on Therapeutic Oligonucleotides. This book focuses on antisense, RNAi, triple-helix, gene repair, DNA chips, and CpG immune modulatory oligonucleotides.

Oligonucleotide Based Drugs and Therapeutics

Oligonucleotide Based Drugs and Therapeutics
  • Author : Nicolay Ferrari,Rosanne Seguin
  • Publisher : John Wiley & Sons
  • Release : 31 July 2018
GET THIS BOOK Oligonucleotide Based Drugs and Therapeutics

A comprehensive review of contemporary antisense oligonucleotides drugs and therapeutic principles, methods, applications, and research Oligonucleotide-based drugs, in particular antisense oligonucleotides, are part of a growing number of pharmaceutical and biotech programs progressing to treat a wide range of indications including cancer, cardiovascular, neurodegenerative, neuromuscular, and respiratory diseases, as well as other severe and rare diseases. Reviewing fundamentals and offering guidelines for drug discovery and development, this book is a practical guide covering all key aspects of this increasingly popular

Oligonucleotides as Therapeutic Agents

Oligonucleotides as Therapeutic Agents
  • Author : Derek J. Chadwick,Gail Cardew
  • Publisher : John Wiley & Sons
  • Release : 30 April 2008
GET THIS BOOK Oligonucleotides as Therapeutic Agents

The use of oligonucleotides as therapeutic agents rests upon their ability to interfere, in a sequence-specific manner, with the fundamental machinery of protein synthesis either by binding to the mRNAs transcribed from a gene or by binding directly to a target gene. This approach can be used not only for inhibition of the synthesis of host proteins but also of those required by invading pathogens. Potential therapeutic applications are enormous, ranging over hypertension, cardiovascular disease, autoimmune disease, vital and other

Protocols for Oligonucleotides and Analogs

Protocols for Oligonucleotides and Analogs
  • Author : Sudhir Agrawal
  • Publisher : Springer Science & Business Media
  • Release : 31 August 1993
GET THIS BOOK Protocols for Oligonucleotides and Analogs

When first conceived, not only was the aim of Protocols for Oligo nucleotides and Analogs to provide wide coverage of the ohgonuc- otide chemistry field for readers who are well versed within the field, but also to give investigators just entering into the field a new perspective. The very first book on this topic was edited and published by Michael Gait in 1984, in whose laboratory I encountered the newer aspects of oligonucleotide chemistry. Since then, oligonucleotide research has developed to