The Molecular And Clinical Pathology Of Neurodegenerative Disease

The Molecular And Clinical Pathology Of Neurodegenerative Disease Book PDF
✏Book Title : The Molecular and Clinical Pathology of Neurodegenerative Disease
✏Author : Patrick A. Lewis
✏Publisher : Academic Press
✏Release Date : 2018-11-16
✏Pages : 274
✏ISBN : 9780128110706
✏Available Language : English, Spanish, And French

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✏The Molecular and Clinical Pathology of Neurodegenerative Disease Book Summary : The Molecular and Clinical Pathology of Neurodegenerative Disease brings together in one volume our current understanding of the molecular basis of neurodegeneration in humans, targeted at neuroscientists and graduate students in neuroscience, and the biomedical and biological sciences. Bringing together up-to-date molecular biology data with clinical evidence, this book sheds a light on common molecular mechanisms that underlie many different neurodegenerative diseases and addresses the molecular pathologies in each. The combined research and clinical background of the authors provides a unique perspective in relating clinical experiences with the molecular understanding needed to examine these diseases and is a must-read for anyone who wants to learn more about neurodegeneration. Provides an up-to-date summary of neurodegeneration at a molecular, cellular, and tissue level for the most common human disorders Describes the clinical background and underlying molecular processes for Alzheimer’s disease, Parkinson’s, Prion, Motor Neuron, Huntington’s, and Multiple Sclerosis Highlights the state-of-the-art treatment options for each disorder Details examples of relevant cutting edge experimental systems, including genome editing and human pluripotent stem cell-derived neuronal models

📒Neurodegeneration ✍ Dennis Dickson

Neurodegeneration Book PDF
✏Book Title : Neurodegeneration
✏Author : Dennis Dickson
✏Publisher : John Wiley & Sons
✏Release Date : 2011-09-09
✏Pages : 432
✏ISBN : 9781444341232
✏Available Language : English, Spanish, And French

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✏Neurodegeneration Book Summary : Most textbooks on neurodegenerative disorders have used a classification scheme based upon either clinical syndromes or anatomical distribution of the pathology. In contrast, this book looks to the future and uses a classification based upon molecular mechanisms, rather than clinical or anatomical boundaries. Major advances in molecular genetics and the application of biochemical and immunocytochemical techniques to neurodegenerative disorders have generated this new approach. Throughout most of the current volume, diseases are clustered according to the proteins that accumulate within cells (e.g. tau, α-synuclein and TDP-43) and in the extracellular compartments (e.g. β-amyloid and prion proteins) or according to a shared pathogenetic mechanism, such as trinucleotide repeats, that are a feature of specific genetic disorders. Chapters throughout the book conform to a standard lay-out for ease of access by the reader and are written by a panel of International Experts Since the first edition of this book, major advances have been made in the discovery of common molecular mechanisms between many neurodegenerative diseases most notably in the frontotemporal lobar degenerations (FTLD) and motor neuron disease or amyotrophic lateral sclerosis. This book will be essential reading for clinicians, neuropathologists and basic neuroscientists who require the firm up-to-date knowledge of mechanisms, diagnostic pathology and genetics of Neurodegenerative diseases that is required for progress in therapy and management.

📒Neurodegenerative Diseases ✍ Daniela Galimberti

Neurodegenerative Diseases Book PDF
✏Book Title : Neurodegenerative Diseases
✏Author : Daniela Galimberti
✏Publisher : Springer Science & Business
✏Release Date : 2014-04-23
✏Pages : 253
✏ISBN : 9781447163800
✏Available Language : English, Spanish, And French

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✏Neurodegenerative Diseases Book Summary : This book gives an overview of the current knowledge on the most common neurodegenerative diseases, including Alzheimer’s disease, frontotemporal lobar degeneration, amyotrophic lateral sclerosis, and additional neurodegenerative diseases. Different aspects of each disease are reviewed, including clinical issues, treatments, basic discoveries (genetics and molecular biology), and translation of basic research into biomarkers for early diagnosis. In addition, emerging data indicate that neurodegeneration seems to also be present in classically non-degenerative disorders. Therefore, a chapter about overlapping mechanisms between dementias and psychiatric disorders is included, as well as a description of the role of neurodegeneration in multiple sclerosis. Neurodegenerative Diseases is aimed at clinicians, particularly those working in academic hospitals. This multidisciplinary book will also be of interest to basic researchers in medical fields.

Neurodegenerative Diseases Book PDF
✏Book Title : Neurodegenerative Diseases
✏Author : Philip Beart
✏Publisher : Springer
✏Release Date : 2017-07-21
✏Pages : 542
✏ISBN : 9783319571935
✏Available Language : English, Spanish, And French

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✏Neurodegenerative Diseases Book Summary : Provides a timely overview of critical advances in molecular and cellular neurobiology, covers key methodologies driving progress, and highlights key future directions for research on neuronal injury and neurodegeneration relevant to neuronal brain pathologies. The editors bring together contributions from internationally recognized workers in the field to provide an up to date account of how and why molecular and cellular neurobiology is such an important area for clinical neuroscience. Understanding the molecular aspects of a number of neurodegenerative conditions such as Parkinson's or Alzheimer's disease for the purpose of improving patient management remains a major challenge of neurobiology be it from the basic or clinical perspective. A strategic evaluation of research contributions and the power of modern methods will help advance knowledge over the next years.

Pathology Prevention And Therapeutics Of Neurodegenerative Disease Book PDF
✏Book Title : Pathology Prevention and Therapeutics of Neurodegenerative Disease
✏Author : Sarika Singh
✏Publisher : Springer
✏Release Date : 2018-09-24
✏Pages : 301
✏ISBN : 9789811309441
✏Available Language : English, Spanish, And French

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✏Pathology Prevention and Therapeutics of Neurodegenerative Disease Book Summary : This book, written by a leading panel of experts in the field of neurosciences, provides a comprehensive overview of the pathology of neurodegenerative diseases as well as the preventive measures. Prevention is important due to the lack of early diagnostic markers and the limitations/ problems of treating neurodegenerative diseases

Cbd Oil For Neurodegenerative Disease Book PDF
✏Book Title : CBD Oil for Neurodegenerative Disease
✏Author : Desmond Cole
✏Publisher :
✏Release Date : 2019-06-17
✏Pages : 36
✏ISBN : 1074420535
✏Available Language : English, Spanish, And French

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✏CBD Oil for Neurodegenerative Disease Book Summary : Neurodegenerative diseases are a major cause of progressive clinical disability causing impaired quality of life with consequences not only for the patient, but also their carer and the state. Global demographics dictate that age-related disorders such as Alzheimer's disease, Parkinson's disease and amyotrophic lateral sclerosis (motor neuron disease) will increase in incidence and prevalence and inevitably present a significant economic challenge to both established and emerging economies [1,2]. There are also many other disorders that fall under the umbrella of neurodegenerative diseases including Huntington's disease, spinocerebellar ataxias, the non-Alzheimer dementias and common problems such as peripheral neuropathy, macular degeneration, and others.The challenge of neurodegenerative diseases needs to be met at several levels. Better facilities must be developed for diagnosis and treatment, and importantly for management of their clinical consequences and of their palliative phase. Undoubtedly the greatest unmet need is the availability of therapeutic interventions that are effective in slowing or preventing progression of the neurodegeneration. Logically, we would hope that a better understanding of the etiology and pathogenesis of these different diseases will provide the platform for the development of drugs targeted to intervene at one or more sites in the pathogenesis cascade. Recent advances in this area provide reason for cautious optimism. Furthermore, the more we learn of the causes of neurodegenerative diseases, the more we begin to appreciate the overlap and commonalities between them in, for instance, pathology and pathogenesis.Thus, there is a need for a greater and more detailed knowledge of the genetic basis and molecular pathology of neurodegenerative diseases. However, this must be matched by better clinical evaluation and understanding of the prodrome and evolution of these diseases and how to detect meaningful change in clinical trials that can reflect successful modification of disease progression in a manner and timescale that is attractive to medical industry.

Molecular Mechanisms Of Neurodegenerative Diseases Book PDF
✏Book Title : Molecular Mechanisms of Neurodegenerative Diseases
✏Author : Marie-Francoise Chesselet
✏Publisher : Springer Science & Business Media
✏Release Date : 2000-10-19
✏Pages : 410
✏ISBN : 9781592590063
✏Available Language : English, Spanish, And French

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✏Molecular Mechanisms of Neurodegenerative Diseases Book Summary : With the unprecedented identification of new mutation mechanisms in neurodegenerative diseases and the emergence of common mechanisms among diseases that were once considered unrelated, neurobiologists are poised for the development of new therapies based on high throughput screenings and a better understanding of the molecular and cellular mechanisms leading to neurodegeneration. In Molecular Mechanisms of Neurodegenerative Diseases, Marie-Francoise Chesselet, MD, PhD, and a panel of leading researchers and neurologists from industry and academia critically review the most recent advances from different yet complementary points of view. Focusing on Alzheimer's, Parkinson's, and CAG triplet repeat diseases, the authors show how studies of cellular and genetically engineered animal models have enhanced our understanding of the molecular mechanisms of neurodegenerative diseases and may lead to the development of new therapeutics. Topics include the role of Ab toxicity, glial cells, and inflammation in Alzheimer's disease; the formation of abnormal protein fragments across several diseases, the impact of dopamine and mitochondrial dysfunction on neurodegeneration; and the potential of genetics to identify the molecular mechanisms of neurodegenerative diseases. Authoritative and insightful, Molecular Mechanisms of Neurodegenerative Diseases synthesizes the novel ideas and concepts now emerging to create a fresh understanding of neurodegenerative disorders, one that promises to lead to powerful new therapies that prevent, delay the onset, slow the progression, or even cure these cruel diseases.

Neurodegeneration Book PDF
✏Book Title : Neurodegeneration
✏Author :
✏Publisher : Wiley-Blackwell
✏Release Date : 2006-07-03
✏Pages : 416
✏ISBN : 3952231312
✏Available Language : English, Spanish, And French

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✏Neurodegeneration Book Summary : Neurodegeneration: The Molecular Pathology of Dementia and Movement Disorders comprises the most recent developments regarding pathology, pathophysiology, as well as the molecular genetics of all major neurodegenerative diseases. In addition, it emphasizes biochemical and genetic aspects of neurodegenerative diseases. It also presents the most important clinical findings, a summary of therapies and available experimental models.

Molecular Pathology In Clinical Practice Book PDF
✏Book Title : Molecular Pathology in Clinical Practice
✏Author : Debra G.B. Leonard
✏Publisher : Springer Science & Business Media
✏Release Date : 2007-11-25
✏Pages : 600
✏ISBN : 9780387332277
✏Available Language : English, Spanish, And French

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✏Molecular Pathology in Clinical Practice Book Summary : This authoritative textbook embodies the current standard in molecular testing for practicing pathologists, and residents and fellows in training. The text is organized into eight sections: genetics, inherited cancers, infectious disease, neoplastic hematopathology, solid tumors, HLA typing, identity testing, and laboratory management. Discussion of each diagnostic test includes its clinical significance, available assays, quality control and lab issues, interpretation, and reasons for testing. Coverage extends to HIV, hepatitis, developmental disorders, bioterrorism, warfare organisms, lymphomas, breast cancer and melanoma, forensics, parentage, and much more. Includes 189 illustrations, 45 in full-color. This textbook is a classic in the making and a must-have reference.

📒Neurodegenerative Diseases ✍ Rommy von Bernhardi

Neurodegenerative Diseases Book PDF
✏Book Title : Neurodegenerative Diseases
✏Author : Rommy von Bernhardi
✏Publisher : Nova Publishers
✏Release Date : 2008
✏Pages : 219
✏ISBN : 160456167X
✏Available Language : English, Spanish, And French

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✏Neurodegenerative Diseases Book Summary : This book discusses in detail the different hypothesis and experimental evidence regarding the neurobiological mechanisms involved in neurodegenerative pathology, with an emphasis in Alzheimer's and Parkinson's disease. Since there are many hypotheses for neurodegenerative diseases, there is a real need for a comprehensive view, allowing for integration of the different views for the pathogenic mechanisms of the disease.

Neuropathology Of Neurodegenerative Diseases Book And Online Book PDF
✏Book Title : Neuropathology of Neurodegenerative Diseases Book and Online
✏Author : Gabor G. Kovacs
✏Publisher : Cambridge University Press
✏Release Date : 2014-12-04
✏Pages : 316
✏ISBN : 9781107442429
✏Available Language : English, Spanish, And French

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✏Neuropathology of Neurodegenerative Diseases Book and Online Book Summary : This heavily illustrated, must-have practical guide aids medical specialists and trainees in the diagnosis of neurodegenerative diseases. Includes diagnostic algorithms.

📒Parkinson S Disease ✍ Patrik Verstreken

Parkinson S Disease Book PDF
✏Book Title : Parkinson s Disease
✏Author : Patrik Verstreken
✏Publisher : Academic Press
✏Release Date : 2016-12-19
✏Pages : 330
✏ISBN : 9780128038055
✏Available Language : English, Spanish, And French

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✏Parkinson s Disease Book Summary : Parkinson’s Disease: Molecular Mechanisms Underlying Pathology explores the molecular pathways at the basis of the cellular defects connected to Parkinson’s disease, the second most common neurodegenerative disease, and the most common movement disorder. This book presents the latest research on the pathways and mechanisms that have been discovered to play a role in Parkinson's pathology. This focus on mechanisms rather than individual genes allows the contributors to elaborate on overlapping and joint functions of different causative genes. Readers will find descriptions of model systems that present parallels (and differences) between discoveries in different species, demonstrating the importance of multidisciplinary research that spans a broad array of technologies and model organisms. Written from both a cross-methodology and cross-species perspective, the book provides readers with the current state of knowledge on the molecular biology of Parkinson’s. Written by experts in the field that focus on pathways and mechanisms implicated in Parkinson’s pathology Draws parallels between multidisciplinary discoveries in different model organisms using an array of technologies Provides a cross-methodology and cross-species approach to understanding the molecular biology of Parkinson’s disease Includes approximately 25 color Illustrations and diagrams to explain concepts and models Focuses on key pathways and mechanisms (as opposed to model organism or gene) to provide a multidisciplinary approach to Parkinson’s disease

Neuropathology Of Neurodegenerative Diseases Book PDF
✏Book Title : Neuropathology of Neurodegenerative Diseases
✏Author : Gabor G. Kovacs
✏Publisher : Cambridge University Press
✏Release Date : 2017-12-28
✏Pages :
✏ISBN : 9781316337653
✏Available Language : English, Spanish, And French

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✏Neuropathology of Neurodegenerative Diseases Book Summary : This practical guide to the diagnosis of neurodegenerative diseases discusses modern molecular techniques, morphological classification, fundamentals of clinical symptomology, diagnostic pitfalls and immunostaining protocols. It is based on the proteinopathy concept of neurodegenerative disease, which has influenced classification and provides new strategies for therapy. Numerous high-quality images, including histopathology photomicrographs and neuroradiology scans, accompany the description of morphologic alterations and interpretation of immunoreactivities. Diagnostic methods and criteria are placed within recent developments in neuropathology, including the now widespread application of immunohistochemistry. To aid daily practice, the guide includes diagnostic algorithms and offers personal insights from experienced experts in the field. Special focus is given to the way brain tissue should be handled during diagnosis. This is a must-have reference for medical specialists and specialist medical trainees in the fields of pathology, neuropathology and neurology working with neuropathologic features of neurodegenerative diseases.

📒Brain Fables ✍ Alberto Espay

Brain Fables Book PDF
✏Book Title : Brain Fables
✏Author : Alberto Espay
✏Publisher : Cambridge University Press
✏Release Date : 2020-06-30
✏Pages : 192
✏ISBN : 9781108744621
✏Available Language : English, Spanish, And French

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✏Brain Fables Book Summary : "In Sapiens, Yuval Noah Harari argues that humankind's greatest invention is our ability to create and believe fictions. While all other animals communicate realities with which they interact, humans create a separate layer of subjective, interpretative realities. The fiction most universally embraced today is money. "Dollar bills have absolutely no value except in our collective imagination, but everybody believes in the dollar bill," says Harari. Harari goes on to state that humans have been living in a dual reality. "On the one hand, the objective reality of rivers, trees, and lions; and on the other hand, the imagined reality of gods, nations, and corporations." In medicine, humans have also created two realities. Clinicians describe what they see, an objective reality, but the medical community then tries to explain and give meaning to what they see, creating a second,"--

Biometals In Neurodegenerative Diseases Book PDF
✏Book Title : Biometals in Neurodegenerative Diseases
✏Author : Anthony R. White
✏Publisher : Academic Press
✏Release Date : 2017-04-28
✏Pages : 462
✏ISBN : 9780128045633
✏Available Language : English, Spanish, And French

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✏Biometals in Neurodegenerative Diseases Book Summary : Biometals in Neurodegenerative Diseases: Mechanisms and Therapeutics is an authoritative and timely resource bringing together the major findings in the field for ease of access to those working in the field or with an interest in metals and their role in brain function, disease, and as therapeutic targets. Chapters cover metals in Alzheimer’s Disease, Parkinson’s Disease, Motor Neuron Disease, Autism and lysosomal storage disorders. This book is written for academic researchers, clinicians and advanced graduate students studying or treating patients in neurodegeneration, neurochemistry, neurology and neurotoxicology. The scientific literature in this field is advancing rapidly, with approximately 300 publications per year adding to our knowledge of how biometals contribute to neurodegenerative diseases. Despite this rapid increase in our understanding of biometals in brain disease, the fields of biomedicine and neuroscience have often overlooked this information. The need to bring the research on biometals in neurodegeneration to the forefront of biomedical research is essential in order to understand neurodegenerative disease processes and develop effective therapeutics. Authoritative and timely resource bringing together the major findings in the field for those with an interest in metals and their role in the brain function, disease, and as therapeutic targets Written for academic researchers, clinicians and advanced graduate students studying, or treating, patients in neurodegeneration, neurochemistry, neurology and neurotoxicology Edited by international leaders in the field who have contributed greatly to the study of metals in neurodegenerative diseases

Imaging In Neurodegenerative Disorders Book PDF
✏Book Title : Imaging in Neurodegenerative Disorders
✏Author : Luca Saba
✏Publisher : Oxford University Press, USA
✏Release Date : 2014-12-11
✏Pages : 562
✏ISBN : 9780199671618
✏Available Language : English, Spanish, And French

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✏Imaging in Neurodegenerative Disorders Book Summary : Diagnosing neurodegenerative diseases can prove particularly intimidating to clinicians, because many times the diagnosis cannot be critically "confirmed" by a simple test. New imaging modalities have advanced to the point of high resolution, morphological, metabolic and functional analysis. Computed tomography, magnetic resonance, nuclear medicine and molecular imaging have recently emerged as outstanding non-invasive techniques for the study of theneurodegenerative disorders. Imaging in Neurodegenerative Disorders covers all the imaging techniques and new exciting methods like new tracers, biomarker, metabolomic and gene-arrayprofiling, potential for applying such techniques clinically, and offers present and future applications as applied to the neurodegenerative disorders with the most world renowned scientists in these fields. The key concepts of pharmacology as well as metabolomic are also covered, making this book an invaluable resource for researchers, clinicians, and trainees in neuroscience, neurology, psychiatry, and radiology.

Molecular Targets In Protein Misfolding And Neurodegenerative Disease Book PDF
✏Book Title : Molecular Targets in Protein Misfolding and Neurodegenerative Disease
✏Author : Pierfausto Seneci
✏Publisher : Academic Press
✏Release Date : 2014-10-07
✏Pages : 314
✏ISBN : 9780128004999
✏Available Language : English, Spanish, And French

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✏Molecular Targets in Protein Misfolding and Neurodegenerative Disease Book Summary : Aimed at "drug discoverers" – i.e. any scientist who is interested in neurodegenerative diseases in general, and in finding disease-modifying treatments in particular – the first edition of Molecular Targets in Protein Misfolding and Neurodegenerative Disease will contain both a detailed, discipline-specific coverage (paragraphs on medicinal chemistry, on clinical and preclinical characterization of compounds in development, on target identification and validation, on genetic factors influencing a pathology, etc.) and a drug discovery-oriented, overall evaluation of each target (validation, druggability, existing leads, etc.). Together these will satisfy the needs of various audiences, including in vitro biologists, pharmacologists, medicinal chemists, etc. Written to provide a comprehensive coverage of disease-modifying mechanisms and compounds against neurodegenerative diseases Provides a “drug discovery application oriented perspective, evaluating targets and candidates for their overall therapeutic potential Provides discipline-specific chapters (medicinal chemistry, target validation, preclinical and clinical development Provides an overview on a number of molecular mechanisms (e.g. phosphorylation, chaperon refolding, ubiquitination, autophagy, microtubule transportation, protease cleavage, etc.) with relevance for any disease area Contains a more thorough description of the therapeutic relevance of ~10 specific molecular targets

Modern Surgical Pathology E Book Book PDF
✏Book Title : Modern Surgical Pathology E Book
✏Author : Noel Weidner
✏Publisher : Elsevier Health Sciences
✏Release Date : 2009-07-08
✏Pages : 2432
✏ISBN : 9781437719581
✏Available Language : English, Spanish, And French

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✏Modern Surgical Pathology E Book Book Summary : Modern Surgical Pathology, 2nd Edition presents today's most complete, current, and practical assistance in evaluating and signing out surgical specimens. Nearly 3,000 high-quality color pathology images provide a crystal-clear basis for comparison to any sample you see under the microscope. Clinical, gross, microscopic, immunohistochemical, and molecular genetic features are integrated as appropriate for all tumors and tumor-like lesions, addressing all of the investigative contexts relevant to formulating an accurate diagnosis. Edited by four leading surgical pathologists - Noel Weidner, MD, Richard J. Cote, MD, Saul Suster, MD and Lawrence M. Weiss, MD - with contributions from more than 70 other experts, Modern Surgical Pathology, 2nd Edition delivers the well-rounded, well-organized, richly illustrated, user-friendly guidance you need to efficiently arrive at confident diagnoses for even the most challenging lesions. Contributions from many leading surgical pathologists give you well-rounded, expert answers to any question that you may face. Clinical, gross, microscopic, immunohistochemical, and molecular genetic features are correlated as appropriate for every type of surgical pathology specimen, addressing all of the investigative contexts relevant to formulating an accurate diagnosis and thereby ensuring a completely accurate surgical report. Nearly 3,000 brand-new, high-quality color pathology images provide a crystal-clear basis for comparison to any specimen you see under the microscope. A completely rewritten section on the female reproductive tract offers many more illustrations of common entities to help you more easily distinguish between tumors and tumor-like lesions. Expanded coverage of non-neoplastic diseases and disorders makes it easier to recognize benign conditions that can mimic malignancy. The latest classification schemes and criteria for malignancy, incorporated throughout, enable you to include the most current gradings in your reports. A new, more consistent organization explores anatomy/histology, gross and microscopic appearance, adjunct techniques, diagnosis, and differential diagnosis for each neoplastic or non-neoplastic lesion, facilitating rapid consultation in the reporting room. An increased number of differential diagnosis and classification tables expedite diagnosis.

Metabolic And Bioenergetic Drivers Of Neurodegenerative Disease Treating Neurodegenerative Diseases As Metabolic Diseases Book PDF
✏Book Title : Metabolic and Bioenergetic Drivers of Neurodegenerative Disease Treating Neurodegenerative Diseases as Metabolic Diseases
✏Author :
✏Publisher : Academic Press
✏Release Date : 2020-09-01
✏Pages : 322
✏ISBN : 9780128231227
✏Available Language : English, Spanish, And French

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✏Metabolic and Bioenergetic Drivers of Neurodegenerative Disease Treating Neurodegenerative Diseases as Metabolic Diseases Book Summary : Metabolic Drivers and Bioenergetic Components of Neurodegenerative Disease reviews how the different aspects of metabolic dysfunction and consequent pathology associated with neurodegenerative diseases, including Alzheimer’s and Parkinson’s, can be targeted by novel treatment approaches. Topics covered include Cellular Senescence in Aging and Age-Related Disorders: Implications for Neurodegenerative Diseases; Repurposing GLP1 agonists for Neurodegenerative Diseases; Ketotherapeutics for Neurodegenerative Diseases; Enhancing Mitophagy as a Therapeutic Approach for Neurodegenerative Diseases; Harnessing Neurogenesis in the Adult Brain – A Role in Type 2 Diabetes Mellitus and Alzheimer’s disease; and much more. Summarizes the impact of the metabolic hypothesis on underlying mechanisms of neurodegenerative diseases Presents novel, potential treatment strategies based on the metabolic hypothesis for neurodegenerative diseases.

Cell And Tissue Based Molecular Pathology E Book Book PDF
✏Book Title : Cell and Tissue Based Molecular Pathology E Book
✏Author : Raymond R. Tubbs
✏Publisher : Elsevier Health Sciences
✏Release Date : 2008-09-22
✏Pages : 452
✏ISBN : 9781437719482
✏Available Language : English, Spanish, And French

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✏Cell and Tissue Based Molecular Pathology E Book Book Summary : This volume in the Foundations in Diagnostic Pathology Series packs today's most essential cell and tissue base molecular pathology into a compact, high-yield format! It focuses on the state of the art in practical validated molecular diagnostics as applied across the fields of surgical pathology and cytology. With an emphasis on current, clinically valid, and diagnostically important applications today and in the near future, you can be assured you’re getting the most up-to-date, authoritative coverage available. Its pragmatic, well-organized approach, nearly 250 full-color illustrations, and at-a-glance boxes and tables make the information you need easy to access. Practical and affordable, this resource is ideal for study and review as well as everyday clinical practice! Offers detailed discussions on today’s technologies to help you select the best test for case evaluation. Presents recognized molecular pathologists who convey the most current information, keeping you on the cusp of your field. Features nearly 250 full-color illustrations that present important pathologic features, enabling you to form a differential diagnosis and compare your findings with actual cases. Uses a consistent, user-friendly format, including at-a-glance boxes and tables for easy reference.

📒Neurodegenerative Diseases ✍ Shamim I. Ahmad

Neurodegenerative Diseases Book PDF
✏Book Title : Neurodegenerative Diseases
✏Author : Shamim I. Ahmad
✏Publisher : Springer Science & Business Media
✏Release Date : 2012-03-12
✏Pages : 390
✏ISBN : 9781461406532
✏Available Language : English, Spanish, And French

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✏Neurodegenerative Diseases Book Summary : The editor of this volume, having research interests in the field of ROS production and the damage to cellular systems, has identified a number of enzymes showing ·OH scavenging activities details of which are anticipated to be published in the near future as confirmatory experiments are awaited. It is hoped that the information presented in this book on NDs will stimulate both expert and novice researchers in the field with excellent overviews of the current status of research and pointers to future research goals. Clinicians, nurses as well as families and caregivers should also benefit from the material presented in handling and treating their specialised cases. Also the insights gained should be valuable for further understanding of the diseases at molecular levels and should lead to development of new biomarkers, novel diagnostic tools and more effective therapeutic drugs to treat the clinical problems raised by these devastating diseases.

Heat Shock Proteins And The Brain Implications For Neurodegenerative Diseases And Neuroprotection Book PDF
✏Book Title : Heat Shock Proteins and the Brain Implications for Neurodegenerative Diseases and Neuroprotection
✏Author : Alexzander A.A. Asea
✏Publisher : Springer Science & Business Media
✏Release Date : 2008-04-06
✏Pages : 373
✏ISBN : 1402082312
✏Available Language : English, Spanish, And French

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✏Heat Shock Proteins and the Brain Implications for Neurodegenerative Diseases and Neuroprotection Book Summary : With the prevalence of neurodegenerative diseases on the rise as average life expectancy increases, the hunt for effective treatments and preventive measures for these disorders is a pressing challenge. Neurodegenerative disorders such as Alzheimer’s disease, Huntington’s disease, Parkinson’s disease and amyotrophic lateral sclerosis have been termed ‘protein misfolding disorders’ that are char- terized by the neural accumulation of protein aggregates. Manipulation of the cellular stress response involving the induction of heat shock proteins offers a the- peutic strategy to counter conformational changes in neural proteins that trigger pathogenic cascades resulting in neurodegenerative diseases. Heat shock proteins are protein repair agents that provide a line of defense against misfolded, aggregati- prone proteins. Heat Shock Proteins and the Brain: Implications for Neurodegenerative Diseases and Neuroprotection reviews current progress on neural heat shock proteins (HSP) in relation to neurodegenerative diseases (Part I), neuroprotection (Part II), ext- cellular HSP (Part III) and aging and control of life span (Part IV). Key basic and clinical research laboratories from major universities and hospitals around the world contribute chapters that review present research activity and importantly project the field into the future. The book is a must read for researchers, postdoctoral fellows and graduate students in the fields of Neuroscience, Neurodegenerative Diseases, Molecular Medicine, Aging, Physiology, Pharmacology and Pathology.

📒Clinical Neuropathology ✍ Catherine Haberland, MD

Clinical Neuropathology Book PDF
✏Book Title : Clinical Neuropathology
✏Author : Catherine Haberland, MD
✏Publisher : Demos Medical Publishing
✏Release Date : 2006-12-27
✏Pages : 304
✏ISBN : 1934559520
✏Available Language : English, Spanish, And French

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✏Clinical Neuropathology Book Summary : Divided into fourteen chapters, this text and full-color atlas is a complete overview of the pathologic and clinical aspects of neurologic diseases. Clinical Neuropathology is written for practicing neurologists and pathologists, as well as residents and fellows preparing for the neurology and pathology boards. It provides information on the structural alterations of nervous system diseases along with their clinical manifestations. The first two chapters cover the process and goals of the neuropathologic exam and histological reactions particular to the nervous system. Subsequent chapters review major disease categories, with each section containing an overview of pathologic and clinical characteristics in general, a description of the gross and histologic features along with their clinical features, and data on pathogenetic mechanisms. Filled with tables to clarify major points, case histories to provide clinical correlates, and Board-type chapter review questions with answers and explanations, this text will be a valuable addition to all individual and reference libraries. Key Benefits: Almost 600 full color illustrations. Case histories, keyed to images, provide clinical correlation with pathology. Over 90 tables summarizing key points: useful for quick reference and exam preparation. End-of-chapter Board-type questions, with answers and explanations, for self-assessment and exam preparation.

Metal Related Neurodegenerative Disease Book PDF
✏Book Title : Metal Related Neurodegenerative Disease
✏Author :
✏Publisher : Academic Press
✏Release Date : 2013-11-07
✏Pages : 434
✏ISBN : 9780124105355
✏Available Language : English, Spanish, And French

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✏Metal Related Neurodegenerative Disease Book Summary : This issue reviews the role of metals in neurodegenerative diseases; including Parkinson’s and Huntington’s disease; restless leg syndrome and NBIA disorders; and Wilson’s disease and manganese and calcium accumulation disorders. An update on advances in neuroimaging and pathology of metal related disease is also presented. This volume of International Review of Neurobiology brings together cutting-edge research on metal related neurodegenerative disease It reviews the role of metals in neurodegenerative diseases, including Parkinson’s and Huntington’s disease; restless leg syndrome and NBIA disorders; and Wilson’s disease and manganese and calcium accumulation disorders An update on advances in neuroimaging and pathology of metal related disease is also presented

Advanced Understanding Of Neurodegenerative Diseases Book PDF
✏Book Title : Advanced Understanding of Neurodegenerative Diseases
✏Author : Raymond Chuen-Chung Chang
✏Publisher : BoD – Books on Demand
✏Release Date : 2011-12-16
✏Pages : 456
✏ISBN : 9789533075297
✏Available Language : English, Spanish, And French

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✏Advanced Understanding of Neurodegenerative Diseases Book Summary : Advanced Understanding of Neurodegenerative Diseases focuses on different types of diseases, including Alzheimer's disease, frontotemporal dementia, different tauopathies, Parkinson's disease, prion disease, motor neuron diseases such as multiple sclerosis and spinal muscular atrophy. This book provides a clear explanation of different neurodegenerative diseases with new concepts of understand the etiology, pathological mechanisms, drug screening methodology and new therapeutic interventions. Other chapters discuss how hormones and health food supplements affect disease progression of neurodegenerative diseases. From a more technical point of view, some chapters deal with the aggregation of prion proteins in prion diseases. An additional chapter to discuss application of stem cells. This book is suitable for different readers: college students can use it as a textbook; researchers in academic institutions and pharmaceutical companies can take it as updated research information; health care professionals can take it as a reference book, even patients' families, relatives and friends can take it as a good basis to understand neurodegenerative diseases.

📒Motor Neuron Disease ✍ P.N. Leigh

Motor Neuron Disease Book PDF
✏Book Title : Motor Neuron Disease
✏Author : P.N. Leigh
✏Publisher : Springer Science & Business Media
✏Release Date : 2012-12-06
✏Pages : 468
✏ISBN : 9781447118718
✏Available Language : English, Spanish, And French

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✏Motor Neuron Disease Book Summary : Here is the first book to provide a comprehensive overview of the clinical, pathological, and research aspects of motor neuron disease (MND). The text contains all essential features of the anatomy, physiology, pharmacology and toxicology of the motor system, a full description of MND and its variants, as well as historical developments and a review of the current concepts and controversies. This book comes at a time of increasing interest in neurodegenerative disorders and MND in particular. It will prove a key reference book with an integrated overview of the field, and will be indispensable to practicing neurologists, researchers, and all those with an interest in MND.

Neurobiology Of Alzheimer S Disease Book PDF
✏Book Title : Neurobiology of Alzheimer s Disease
✏Author : David Dawbarn
✏Publisher : Oxford University Press, USA
✏Release Date : 2007
✏Pages : 468
✏ISBN : 0198566611
✏Available Language : English, Spanish, And French

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✏Neurobiology of Alzheimer s Disease Book Summary : Alzheimer's disease is the most common form of dementia in the elderly; 450,000 people in the UK and 4.5 million people in the USA suffer with this disease. This 3rd edition of Neurobiology of Alzheimer's Disease gives a comprehensive and readable introduction to the disease, from molecular pathology to clinical practice. The book is intended for readers new to the field, and it also covers an extensive range of themes for those with in-depth knowledge of Alzheimer's disease. It will therefore act either as an introduction to the whole field of neurodegeneration or it will help experienced researchers to access the latest research in specialist topics. Each chapter is written by eminent scientists leading their fields in neuropathology, clinical practice and molecular neurobiology; appendices detail disease-associate proteins, their sequences, familial mutations and known structures. It will be essential reading for students interested in neurodegeneration and for researchers and clinicians, giving a coherent and cohesive approach to the whole area of research, and allowing access at different levels. For those in the pharmaceutical industry it describes the underlying molecular mechanisms involved in the pathogenesis of Alzheimer's disease and explains how current and potential therapeutics may work.

Directory Of Pathology Training Programs In The United States And Canada Book PDF
✏Book Title : Directory of Pathology Training Programs in the United States and Canada
✏Author :
✏Publisher :
✏Release Date : 2008
✏Pages :
✏ISBN : CHI:76992348
✏Available Language : English, Spanish, And French

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✏Directory of Pathology Training Programs in the United States and Canada Book Summary : Directory intended to give "medical students and graduate physicians a timely source of detailed information about the many options for pathology training in the United States and Canada." Geographical arrangement. Entries give in narrative such information as programs offered, facilities, community environment, stipends, staff, and application. Training staff index.

Essential Concepts In Molecular Pathology Book PDF
✏Book Title : Essential Concepts in Molecular Pathology
✏Author : William B. Coleman
✏Publisher : Academic Press
✏Release Date : 2010-02-16
✏Pages : 462
✏ISBN : 008092218X
✏Available Language : English, Spanish, And French

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✏Essential Concepts in Molecular Pathology Book Summary : This streamlined "essential" version of the Molecular Pathology (2009) textbook extracts key information, illustrations and photographs from the main textbook in the same number and organization of chapters. It is aimed at teaching students in courses where the full textbook is not needed, but the concepts included are desirable (such as graduate students in allied health programs or undergraduates). It is also aimed at students who are enrolled in courses that primarily use a traditional pathology textbook, but need the complementary concepts of molecular pathology (such as medical students). Further, the textbook will be valuable for pathology residents and other postdoctoral fellows who desire to advance their understanding of molecular mechanisms of disease beyond what they learned in medical/graduate school. Offers an essential introduction to molecular genetics and the "molecular" aspects of human disease Teaches from the perspective of "integrative systems biology," which encompasses the intersection of all molecular aspects of biology, as applied to understanding human disease In-depth presentation of the principles and practice of molecular pathology: molecular pathogenesis, molecular mechanisms of disease, and how the molecular pathogenesis of disease parallels the evolution of the disease using histopathology. "Traditional" pathology section provides state-of-the-art information on the major forms of disease, their pathologies, and the molecular mechanisms that drive these diseases. Explains the practice of "molecular medicine" and the translational aspects of molecular pathology: molecular diagnostics, molecular assessment, and personalized medicine Each chapter ends with Key Summary Points and Suggested Readings

The Neuropsychology Of Cortical Dementias Book PDF
✏Book Title : The Neuropsychology of Cortical Dementias
✏Author : Mary Anderson, PhD
✏Publisher : Springer Publishing Company
✏Release Date : 2014-12-16
✏Pages : 468
✏ISBN : 9780826107275
✏Available Language : English, Spanish, And French

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✏The Neuropsychology of Cortical Dementias Book Summary : "This book provides an overview of the cognitive and behavioral profiles of the cortical dementias in a readable and clinically relevant manner. Its emphasis on disease entities primarily affecting cortical structures allows for a more comprehensive description of the latest insights into the pathogenesis and assessment of a number of different disease processes... Weighted Numerical Score: 98 - 5 Stars!" Melissa Jones, MD (University of Illinois at Chicago College of Medicine) Doody's Medical Reviews The Neuropsychology of Cortical Dementias addresses in depth the neuropsychological impact and features of the full range of cortical dementias. It examines the differential neuropathological and pathophysiological bases of these dementias and emphasizes their behavioral and cognitive aspects in assessment, diagnosis, and treatment. The book also presents the most advanced techniques and strategies for disease-specific treatment. Important legal/ethical issues and the role of caregivers in treating dementia patients are also covered. Featuring contributions from such diverse disciplines as neuropsychology, neurology, psychiatry, and clinical psychology, this volume provides a broad interdisciplinary perspective for practicing clinical neuropsychologists, neurologists, psychiatrists, gerontologists, and psychologists who work with patients with dementia. Key Features: Includes comprehensive, clinically focused coverage of all major cortical dementias Covers neuroanatomy, assessment, diagnosis, treatment, and management of dementia patients, as well as legal and ethical issues Discusses assessment and diagnosis from the perspectives of neuroimaging and cognitive and behavioral symptoms Discusses a range of interventions (pharmacological, cognitive behavioral, etc.) and management issues related to dementia treatment Informed by contributions from such diverse disciplines as neuropsychology, neurology, psychiatry, and clinical psychology