The Molecular and Cellular Basis of Neurodegenerative Diseases

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  • Author : Michael S. Wolfe
  • Publisher : Academic Press
  • Pages : 560 pages
  • ISBN : 0128113057
  • Rating : /5 from reviews
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Download or Read online The Molecular and Cellular Basis of Neurodegenerative Diseases full in PDF, ePub and kindle. this book written by Michael S. Wolfe and published by Academic Press which was released on 29 March 2018 with total page 560 pages. We cannot guarantee that The Molecular and Cellular Basis of Neurodegenerative Diseases book is available in the library, click Get Book button and read full online book in your kindle, tablet, IPAD, PC or mobile whenever and wherever You Like. The Molecular and Cellular Basis of Neurodegenerative Diseases: Underlying Mechanisms presents the pathology, genetics, biochemistry and cell biology of the major human neurodegenerative diseases, including Alzheimer’s, Parkinson’s, frontotemporal dementia, ALS, Huntington’s, and prion diseases. Edited and authored by internationally recognized leaders in the field, the book's chapters explore their pathogenic commonalities and differences, also including discussions of animal models and prospects for therapeutics. Diseases are presented first, with common mechanisms later. Individual chapters discuss each major neurodegenerative disease, integrating this information to offer multiple molecular and cellular mechanisms that diseases may have in common. This book provides readers with a timely update on this rapidly advancing area of investigation, presenting an invaluable resource for researchers in the field. Covers the spectrum of neurodegenerative diseases and their complex genetic, pathological, biochemical and cellular features Focuses on leading hypotheses regarding the biochemical and cellular dysfunctions that cause neurodegeneration Details features, advantages and limitations of animal models, as well as prospects for therapeutic development Authored by internationally recognized leaders in the field Includes illustrations that help clarify and consolidate complex concepts

The Molecular and Cellular Basis of Neurodegenerative Diseases

The Molecular and Cellular Basis of Neurodegenerative Diseases
  • Author : Michael S. Wolfe
  • Publisher : Academic Press
  • Release : 29 March 2018
GET THIS BOOK The Molecular and Cellular Basis of Neurodegenerative Diseases

The Molecular and Cellular Basis of Neurodegenerative Diseases: Underlying Mechanisms presents the pathology, genetics, biochemistry and cell biology of the major human neurodegenerative diseases, including Alzheimer’s, Parkinson’s, frontotemporal dementia, ALS, Huntington’s, and prion diseases. Edited and authored by internationally recognized leaders in the field, the book's chapters explore their pathogenic commonalities and differences, also including discussions of animal models and prospects for therapeutics. Diseases are presented first, with common mechanisms later. Individual chapters discuss each major neurodegenerative

The Molecular and Cellular Basis for Parkinson s Disease

The Molecular and Cellular Basis for Parkinson s Disease
  • Author : Thomas Müller
  • Publisher : MDPI
  • Release : 14 October 2019
GET THIS BOOK The Molecular and Cellular Basis for Parkinson s Disease

The focus on dopamine-sensitive motor symptoms, in association with the improvement of motor complications in the heterogeneous disease entity Parkinson's disease, has led to a certain standstill in research.This Special Issue provides new concepts and new ideas on the pathogenesis, genetics, and clinical maintenance of Parkinson's disease and related disorders. Not only new experimental findings, but also clinical outcomes, case series, and research on alternative, non-pharmacological therapies are included.The objective is to bridge the currently increasing

Estrogen Mystery Drug for the Brain

Estrogen     Mystery Drug for the Brain
  • Author : Christian Behl
  • Publisher : Springer Science & Business Media
  • Release : 28 June 2011
GET THIS BOOK Estrogen Mystery Drug for the Brain

It is well known that estrogen is "somehow” a protective hormone for various age-related disorders. This book provides a solid knowledge of estrogen’s neuroprotective activities in the brain with a special emphasis on neurodegenerative disorders such as Alzheimer’s Disease. The focus is (1) to describe the biochemical, molecular, and cellular basis of the protective activity of estrogen and (2) to transfer this knowledge into the hospitals by discussing preventive and therapeutic approaches such as estrogen replacement therapy for post-menopausal women.

The Molecular and Cellular Basis of Retinal Diseases

The Molecular and Cellular Basis of Retinal Diseases
  • Author : Steven J. Pittler ,Steven J. Fliesler
  • Publisher : MDPI
  • Release : 29 December 2020
GET THIS BOOK The Molecular and Cellular Basis of Retinal Diseases

There are more than 300 genes that have been identified which carry mutations that cause various forms of retinal dysfunction and degeneration, making the study of retinal diseases a subject of high relevance. In this compendium of original and review articles, many of the diseases and pathways associated with disorders of the retina are examined using animal models, to provide the reader with a good overview of current retinal research. Within this volume, you will find research reports on many of

Parkinson s Disease

Parkinson s Disease
  • Author : Patrik Verstreken
  • Publisher : Academic Press
  • Release : 19 December 2016
GET THIS BOOK Parkinson s Disease

Parkinson’s Disease: Molecular Mechanisms Underlying Pathology explores the molecular pathways at the basis of the cellular defects connected to Parkinson’s disease, the second most common neurodegenerative disease, and the most common movement disorder. This book presents the latest research on the pathways and mechanisms that have been discovered to play a role in Parkinson's pathology. This focus on mechanisms rather than individual genes allows the contributors to elaborate on overlapping and joint functions of different causative genes. Readers

Drosophila Glia

Drosophila Glia
  • Author : LinFang Wang,Honglei Wang,Margaret S. Ho
  • Publisher : Biota Publishing
  • Release : 18 March 2019
GET THIS BOOK Drosophila Glia

Glia, the non-neuronal cells in the nervous systems, are both passive and active participants in diverse arrays of neuronal function. The diversity of glial cells in various animal species appears to be correlated with the complexity of brains. In the animal Drosophila melanogaster, glia are similarly categorized to their mammalian counterparts in morphology and function. Surface glia cover the outermost surface of the brain and function as a blood-brain-barrier to protect the nervous system. Cortex glia, similar to mammalian astrocytes,

Environmental Contaminants and Neurological Disorders

Environmental Contaminants and Neurological Disorders
  • Author : Muhammad Sajid Hamid Akash,Kanwal Rehman
  • Publisher : Springer Nature
  • Release : 17 May 2021
GET THIS BOOK Environmental Contaminants and Neurological Disorders

This volume discusses how environmental pollutants are involved in the pathogenesis of neurological disorders, and covers specific mechanisms and risk factors, as well as the necessary strategies to reduce the adverse impacts of environmental pollutants on the human nervous system. With a collection of contributions from experts in environmental pollution, neurology and pharmaceutical chemistry, the book provides both an introduction to the pathogenesis of neurodegeneration, including the types and different classes of neurological disorders, and studies demonstrating the clear link

Antioxidants and Functional Foods for Neurodegenerative Disorders

Antioxidants and Functional Foods for Neurodegenerative Disorders
  • Author : Abhai Kumar,Debasis Bagchi
  • Publisher : CRC Press
  • Release : 07 January 2021
GET THIS BOOK Antioxidants and Functional Foods for Neurodegenerative Disorders

Neurodegenerative diseases, including Alzheimer’s and Parkinson’s disease, are a growing problem across the world’s aging population. Oxidative stress in the brain plays a central role in a common pathophysiology of these diseases. This book presents scientific research on the potential of antioxidant therapy in the prevention and treatment of neurodegenerative disorders. This book outlines the roles of oxidative stress and diabetes mellitus in neurodegeneration, describes the molecular mechanisms of neurodegenerative disorders including the roles of environmental pollutants

Insights into Human Neurodegeneration Lessons Learnt from Drosophila

Insights into Human Neurodegeneration  Lessons Learnt from Drosophila
  • Author : Mousumi Mutsuddi,Ashim Mukherjee
  • Publisher : Springer Nature
  • Release : 05 December 2019
GET THIS BOOK Insights into Human Neurodegeneration Lessons Learnt from Drosophila

This book is aimed at generating an updated reservoir of scientific endeavors undertaken to unravel the complicated yet intriguing topic of neurodegeneration. Scientists from Europe, USA and India who are experts in the field of neurodegenerative diseases have contributed to this book. This book will help readers gain insight into the recent knowledge obtained from Drosophila model, in understanding the molecular mechanisms underlying neurodegenerative disorders and also unravel novel scopes for therapeutic interventions. Different methodologies available to create humanized fly

The Molecular Basis for Neurodegenerative Diseases

The Molecular Basis for Neurodegenerative Diseases
  • Author : Daniel Offen
  • Publisher : Unknown
  • Release : 01 January 2007
GET THIS BOOK The Molecular Basis for Neurodegenerative Diseases

Neurodegenerative disorders are characterized by progressive atrophy and dysfunction of anatomically or physiologically related neurologic systems. There are several common features of neurodegenerative disorders. They are mostly chronic, progressive and start due to the death of specific neuronal populations in the central nerve system (CNS). The distinct clinical phenotypes are generally linked to neuronal loss and often associated with aging. These disorders might share common pathogenetic mechanisms such as intracytoplasmic or intranuclear inclusions in neurons or glia which are linked

Advances in Medical Biochemistry Genomics Physiology and Pathology

Advances in Medical Biochemistry  Genomics  Physiology  and Pathology
  • Author : Raj Bawa,Esther H. Chang,Gerald F. Audette,Anil Diwan,Saadia A. Faiz
  • Publisher : CRC Press
  • Release : 23 December 2021
GET THIS BOOK Advances in Medical Biochemistry Genomics Physiology and Pathology

The pace and sophistication of advances in medicine in the past two decades have necessitated a growing need for a comprehensive reference that highlights current issues in medicine. Each volume in the Current Issues in Medicine series is a stand‐alone text that provides a broad survey of various critical topics—all accomplished in a user-friendly yet interconnected format. The series not only highlights current advances but also explores related topics such as translational medicine, regulatory science, neglected diseases, global

The Molecular and Clinical Pathology of Neurodegenerative Disease

The Molecular and Clinical Pathology of Neurodegenerative Disease
  • Author : Patrick A. Lewis,Jennifer E. Spillane
  • Publisher : Academic Press
  • Release : 16 November 2018
GET THIS BOOK The Molecular and Clinical Pathology of Neurodegenerative Disease

The Molecular and Clinical Pathology of Neurodegenerative Disease brings together in one volume our current understanding of the molecular basis of neurodegeneration in humans, targeted at neuroscientists and graduate students in neuroscience, and the biomedical and biological sciences. Bringing together up-to-date molecular biology data with clinical evidence, this book sheds a light on common molecular mechanisms that underlie many different neurodegenerative diseases and addresses the molecular pathologies in each. The combined research and clinical background of the authors provides a

Protein Misfolding

Protein Misfolding
  • Author : Rossen Donev
  • Publisher : Academic Press
  • Release : 17 January 2020
GET THIS BOOK Protein Misfolding

Protein Misfolding, Volume 118, covers the wide spectrum of diseases and disorders that are attributed to protein misfolding, including degenerative and neurodegenerative, cardiovascular, renal, glaucoma, cancer, cystic fibrosis, Gaucher's disease, and many others. Specific chapters cover Mass spectrometric approaches for profiling protein folding and stability, Biomembranes, a key player in protein misfolding, how Genetic and environmental factors interact to disrupt proteostasis and trigger protein misfolding diseases, Formation of oligomers and large amorphous aggregates by intrinsically disordered proteins, Protein misfolding in ER