The Immune System

The Immune System A Very Short Introduction Book PDF
✏Book Title : The Immune System a Very Short Introduction
✏Author : Paul Klenerman
✏Publisher : Oxford University Press
✏Release Date : 2017-10-26
✏Pages : 144
✏ISBN : 9780198753902
✏Available Language : English, Spanish, And French

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✏The Immune System a Very Short Introduction Book Summary : The immune system is central to human health and the focus of much medical research. Growing understanding of the immune system, and especially the creation of immune memory (long lasting protection), which can be harnessed in the design of vaccines, have been major breakthroughs in medicine. In this Very Short Introduction, Paul Klenerman describes the immune system, and how it works in health and disease. In particular he focuses on the human immune system, considering how it evolved, the basic rules that govern its behavior, and the major health threats where it is important. The immune system comprises a series of organs, cells and chemical messengers which work together as a team to provide defence against infection. Klenerman discusses these components, the critical signals that trigger them and how they exert their protective effects, including so-called "innate" immune responses, which react very fast to infection, and "adaptive" immune responses, which have huge diversity and a capacity to recognize and defend against a massive array of micro-organisms. Klenerman also considers what happens when our immune systems fail to be activated effectively, leading to serious infections, problems with inherited diseases, and also HIV/AIDS. At the opposite extreme, as Klenerman shows, an over-exaggerated immune response leads to inflammatory diseases such as Multiple Sclerosis and Rheumatoid Arthritis, as well as allergy and asthma. Finally he looks at the "Immune system v2.o" - how immune therapies and vaccines can be advanced to protect us against the major diseases of the 21st century. ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.

📒How The Immune System Works ✍ Lauren M. Sompayrac

How The Immune System Works Book PDF
✏Book Title : How the Immune System Works
✏Author : Lauren M. Sompayrac
✏Publisher : John Wiley & Sons
✏Release Date : 2019-04-15
✏Pages : 168
✏ISBN : 9781119542124
✏Available Language : English, Spanish, And French

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✏How the Immune System Works Book Summary : How the Immune System Works has helped thousands of students understand what's in their hefty immunology textbooks. In this book, Dr. Sompayrac cuts through the jargon and details to reveal, in simple language, the essence of this complex subject: how the immune system fits together, how it protects us from disease and, perhaps most importantly, why it works the way it does. Featuring Dr. Sompayrac's hallmark lively prose and engaging analogies, How the Immune System Works has been rigorously updated for this sixth edition, including the latest information on subjects such as vaccines, immunological memory, and cancer. A highlight of this edition is a new chapter on immunotherapies – currently one of the hottest topics in immunology. Whether you are completely new to immunology, or require a refresher, How the Immune System Works will provide you with a clear and engaging overview of this fascinating subject.

📒Immune System ✍ Lorrie Klosterman

Immune System Book PDF
✏Book Title : Immune System
✏Author : Lorrie Klosterman
✏Publisher : Marshall Cavendish
✏Release Date : 2009
✏Pages : 80
✏ISBN : 0761430547
✏Available Language : English, Spanish, And French

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✏Immune System Book Summary : "Discusses the parts that make up the human immune system, what can go wrong, how to treat those illnesses and diseases, and how to stay healthy"--Provided by publisher.

📒The Immune System ✍ Parham, Peter

The Immune System Book PDF
✏Book Title : The Immune System
✏Author : Parham, Peter
✏Publisher : W.W. Norton & Company
✏Release Date : 2014-10-01
✏Pages : 624
✏ISBN : 9780815345275
✏Available Language : English, Spanish, And French

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✏The Immune System Book Summary : This text emphasizes the human immune system and presents concepts with a balanced level of detail to describe how the immune system works. Written for undergraduate, medical, veterinary, dental, and pharmacy students, it makes generous use of medical examples to illustrate points. This classroom-proven textbook offers clear writing, full-color illustrations, and section and chapter summaries that make the content accessible and easily understandable to students.

📒Basic Immunology E Book ✍ Abul K. Abbas

Basic Immunology E Book Book PDF
✏Book Title : Basic Immunology E Book
✏Author : Abul K. Abbas
✏Publisher : Elsevier Health Sciences
✏Release Date : 2012-11-05
✏Pages : 336
✏ISBN : 9781455758999
✏Available Language : English, Spanish, And French

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✏Basic Immunology E Book Book Summary : Understand all the essential concepts in immunology with Basic Immunology: Functions and Disorders of the Immune System! This concise, focused text provides you with an up-to-date, accessible introduction to the workings of the human immune system. Efficiently master the immunology information you need through clinically focused content, logically organized by mechanism. Apply what you've learned to real-world situations by referencing the appendix of clinical cases. Enhance your learning with the help of numerous full-color illustrations and useful tables, as well as summary boxes, review questions, and a glossary of immunology terms. Study immunology anywhere! Online access to www.StudentConsult.com opens the door to an enhanced e-book and ancillary components! Visualize complex immunology concepts with a completely updated art program. Test your knowledge. New PowerPoint Review slides added to www.StudentConsult.com are ideal for study sessions.

📒Body Warriors ✍ Lisa Trumbauer

Body Warriors Book PDF
✏Book Title : Body Warriors
✏Author : Lisa Trumbauer
✏Publisher : Heinemann-Raintree Library
✏Release Date : 2007
✏Pages : 32
✏ISBN : 1410925811
✏Available Language : English, Spanish, And French

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✏Body Warriors Book Summary : Deep in your body warriors are fighting an epic battle to keep you safe and healthy. Read this book to learn all about the tiny heroes you depend on.

📒Immunity ✍ Anthony DeFranco

Immunity Book PDF
✏Book Title : Immunity
✏Author : Anthony DeFranco
✏Publisher : New Science Press
✏Release Date : 2007-04-05
✏Pages : 387
✏ISBN : 9780199206148
✏Available Language : English, Spanish, And French

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✏Immunity Book Summary : Immunity: The Immune Response to Infectious and Inflammatory Disease presents an engaging insight into one of the most intricate yet conceptually challenging biological systems. With a unique emphasis on the immune response to infection, it builds up a complete picture of the immune system as a dynamic interface with the outside world.

📒The Immune Response To Infection ✍ Stefan H. E. Kaufmann

The Immune Response To Infection Book PDF
✏Book Title : The Immune Response to Infection
✏Author : Stefan H. E. Kaufmann
✏Publisher : American Society for Microbiology Press
✏Release Date : 2010-11-30
✏Pages : 666
✏ISBN : 9781555815141
✏Available Language : English, Spanish, And French

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✏The Immune Response to Infection Book Summary : Examines the mechanisms of both the innate and adaptive immune systems as they relate to infection and disease. • Explores the underlying mechanisms of immunity and the many sequelae of host-pathogen interactions, ranging from the sterile eradication of the invader, to controlled chronic infection, to pathologic corollaries of the host-pathogen crosstalk. • Discusses the pathogenesis of certain autoimmune disorders and cancers that are induced by infectious agents but then become independent of the infection process. • Serves as a resource for immunologists, molecular microbiologists, infectious disease clinicians, researchers, and students.

Artificial Immune Systems And Their Applications Book PDF
✏Book Title : Artificial Immune Systems and Their Applications
✏Author : Dipankar Dasgupta
✏Publisher : Springer Science & Business Media
✏Release Date : 2012-12-06
✏Pages : 306
✏ISBN : 9783642599019
✏Available Language : English, Spanish, And French

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✏Artificial Immune Systems and Their Applications Book Summary : This is a pioneering work on the emerging field of artificial immune systems-highly distributed systems based on the principles of the natural system. Like artificial neural networks, artificial immune systems can learn new information and recall previously learned information. This book provides an overview of artificial immune systems, explaining its applications in areas such as immunological memory, anomaly detection algorithms, and modeling the effects of prior infection on vaccine efficacy.

Bacterial Exotoxins How Bacteria Fight The Immune System Book PDF
✏Book Title : Bacterial Exotoxins How Bacteria Fight the Immune System
✏Author : Inka Sastalla
✏Publisher : Frontiers Media SA
✏Release Date : 2016-10-07
✏Pages :
✏ISBN : 9782889199914
✏Available Language : English, Spanish, And French

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✏Bacterial Exotoxins How Bacteria Fight the Immune System Book Summary : Bacterial pathogenicity factors are functionally diverse. They may facilitate the adhesion and colonization of bacteria, influence the host immune response, assist spreading of the bacterium by e.g. evading recognition by immune cells, or allow bacteria to dwell within protected niches inside the eukaryotic cell. Exotoxins can be single polypeptides or heteromeric protein complexes that act on different parts of the cells. At the cell surface, they may insert into the membrane to cause damage; bind to receptors to initiate their uptake; or facilitate the interaction with other cell types. For example, bacterial superantigens specifically bind to major histocompatibility complex (MHC) II molecules on the surface of antigen presenting cells and the T cell receptor, while cytolysins cause pore formation. For intracellular activity, exotoxins need to be translocated across the eukaryotic membrane. Gram-negative bacteria can directly inject effector proteins in a receptor-independent manner by use of specialized needle apparatus such as bacterial type II, III, or type IV secretion systems. Other methods of translocation include the phagocytic uptake of bacteria followed by toxin secretion, or receptor-mediated endocytosis which allows the targeting of distinct cell types. Receptor-based uptake is initiated by the binding of heteromeric toxin complexes to the cell surface and completed by the translocation of the effector protein(s) across the endosomal membrane. In the cytosol, toxins interact with specific eukaryotic target proteins to cause post-translational modifications that often result in the manipulation of cellular signalling cascades and inflammatory responses. It has become evident that the actions of some bacterial toxins may exceed their originally assumed cytotoxic function. For example, pore-forming toxins do not only cause cytolysis, but may also induce autophagy, pyroptosis, or activation of the MAPK pathways, resulting in adjustment of the host immune response to infection and modification of inflammatory responses both locally and systemically. Other recently elucidated examples of the immunomodulatory function of cell death-inducing exotoxins include TcdB of Clostridium difficile which activates the inflammasome through modification of cellular Rho GTPases, or the Staphyloccocus d-toxin which activates mast cells. The goal of this research topic was to gather current knowledge on the interaction of bacterial exotoxins and effector proteins with the host immune system. The following 16 research and review articles in this special issue describe mechanisms of immune modification and evasion and provide an overview over the complexity of bacterial toxin interaction with different cells of the immune system.

📒Basic Immunology ✍ Abul K. Abbas

Basic Immunology Book PDF
✏Book Title : Basic Immunology
✏Author : Abul K. Abbas
✏Publisher : Elsevier Health Sciences
✏Release Date : 2015-11-02
✏Pages : 352
✏ISBN : 9780323390828
✏Available Language : English, Spanish, And French

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✏Basic Immunology Book Summary : Understand all the essential concepts in immunology with this book that provides you with an up-to-date, accessible introduction to the workings of the human immune system. This book enables you to efficiently master the immunology information you need through clinically focused content, logically organized by mechanism. You can apply what you have learned to real-world situations by referencing the appendix of clinical cases. It can enhance your learning with the help of numerous full-color illustrations and useful tables, as well as summary boxes, review questions, and a glossary of immunology terms. -- Publisher description.

The Immune System And Mental Health Book PDF
✏Book Title : The Immune System and Mental Health
✏Author : Hymie Anisman
✏Publisher : Academic Press
✏Release Date : 2018-07-19
✏Pages : 700
✏ISBN : 9780128113523
✏Available Language : English, Spanish, And French

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✏The Immune System and Mental Health Book Summary : The Immune System and Mental Health fully investigates how immune-related cellular, molecular and anatomical changes impact mental functioning. The book combines human and animal studies to reveal immunological changes related to mental-health problems. In addition, users will find comprehensive information on new research related to the microbial composition of the gut, aka, the microbiome, and how it influences brain function and mental health. Common comorbidities with mental illness and their inherent immunological or inflammatory components are also covered. Written by leaders in the field, the book synthesizes basic and clinical research to provide a thorough understanding on the role of immunity in neuropsychiatry. Sociology, psychology, psychiatry, neuroscience and genetics have provided considerable explanations and solutions to some of the most intractable mental-health problems. But researchers are increasingly relying on investigations of the immune system to identify factors that can undermine and impair mental health. This book covers devastating mental-health conditions, such as depression, anxiety, schizophrenia, and autism-like spectrum disorders. In addition, degenerative disorders of the brain, such as Parkinson’s and Alzheimer’s-like dementia are explored. Considers both basic human and animal studies that address immunological changes relating to mental health problems across the lifespan Incorporates techniques, concepts and ideas from a variety of social, behavioral and life sciences Explores the relatively new area of the microbiome and how the microbial composition of the gut influences brain function and mental health

📒Boosting The Immune System ✍ Case Adams Naturopath

Boosting The Immune System Book PDF
✏Book Title : Boosting the Immune System
✏Author : Case Adams Naturopath
✏Publisher :
✏Release Date : 2014-01
✏Pages : 414
✏ISBN : 1936251442
✏Available Language : English, Spanish, And French

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✏Boosting the Immune System Book Summary : Our body's immune system has not been that well understood to date. While immunity has been the focus of medical study from a disease perspective, many of its functional characteristics have eluded scientists. This is evidenced by the fact that many infections are becoming resistant to many drugs - and numerous bacteria and viruses are now multi-drug resistant. Here, in a groundbreaking compendium of the latest immunity research, the author reveals our immune system in a way that has vast implications for global and personal wellness. The vibrant, dynamic nature of our immune system is documented in detail, showing the interplay between immune cells, cytokines, immunoglobulins, probiotics and the many other immune system components that help us fight off colds, flu, infections, chronic fatigue and other diseases. The author - a California Naturopath and board certified Alternative Medical Practitioner - then unveils a host of natural strategies, including probiotics, diet, herbs and lifestyle factors, while referencing hundreds of clinical studies proving their ability to supercharge our immune system and help our bodies fight disease.

📒Basic Immunology ✍ Abul K. Abbas

Basic Immunology Book PDF
✏Book Title : Basic Immunology
✏Author : Abul K. Abbas
✏Publisher : W B Saunders Company
✏Release Date : 2011
✏Pages : 312
✏ISBN : NWU:35558005794173
✏Available Language : English, Spanish, And French

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✏Basic Immunology Book Summary : Understand all the essential concepts in immunology with Basic Immunology: Functions and Disorders of the Immune System! This concise, focused text provides you with an up-to-date, accessible introduction to the workings of the human immune system. Efficiently master the immunology information you need through clinically focused content, logically organized by mechanism. Apply what you've learned to real-world situations by referencing the appendix of clinical cases. Enhance your learning with the help of numerous full-color illustrations and useful tables, as well as summary boxes, review questions, and a glossary of immunology terms.Study immunology anywhere! Online access to www.StudentConsult.com opens the door to ancillary components such as an image bank, additional tables, a glossary of immunology terms, animations, and PowerPoint review slides!

Artificial Immune Systems A New Computational Intelligence Approach Book PDF
✏Book Title : Artificial Immune Systems A New Computational Intelligence Approach
✏Author : Leandro Nunes Castro
✏Publisher : Springer Science & Business Media
✏Release Date : 2002-09-23
✏Pages : 357
✏ISBN : 1852335947
✏Available Language : English, Spanish, And French

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✏Artificial Immune Systems A New Computational Intelligence Approach Book Summary : Recently there has been a growing interest in the use of the biological immune system as a source of inspiration for solving complicated computational problems. The immune system involves many information-processing abilities including pattern recognition, learning, memory and inherent distributed parallel processing and for these, and other reasons, it has received a significant amount of interest as a metaphor within computing. This emerging field is known as Artificial Immune Systems (AIS), and applications of AIS include, machine learning, fault diagnosis, computer security, scheduling, virus detection and optimisation.

📒In Defense Of Self ✍ William R. Clark

In Defense Of Self Book PDF
✏Book Title : In Defense of Self
✏Author : William R. Clark
✏Publisher : Oxford University Press, USA
✏Release Date : 2008
✏Pages : 265
✏ISBN : 9780195335552
✏Available Language : English, Spanish, And French

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✏In Defense of Self Book Summary : William Clark invites readers on a tour of the immune system, introducing some of the most important medical advances and challenges of the past 100 years, from the development of vaccines and the treatment of allergies, automimmunity and cancer, to prolonging organ transplants and combating AIDS.

Immunobiology 5 The Immune System In Health And Disease Book PDF
✏Book Title : Immunobiology 5 the Immune System in Health and Disease
✏Author : Charles Janeway
✏Publisher : Garland Science
✏Release Date : 2001
✏Pages : 732
✏ISBN : 081533642X
✏Available Language : English, Spanish, And French

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✏Immunobiology 5 the Immune System in Health and Disease Book Summary : Designed for providers who work with judicial clients, the Providers Guide presents effective cognitive-behavioral treatment approaches. The Second Edition of this bestseller unveils a state-of-the-art approach for effectively preventing criminal recidivism and substance abuse relapse within community based and correctional settings. The core of the SSC program is a positive relationship between provider and client. Summary of results survey from the first edition of SSC 95% of the providers rated the components of SSC to be adequate to very adequate in meeting the treatment needs of judicial clients Over 90% of providers rated clients as having a moderate to very high involvement in homework and reading 95% of the clients rates as very high their satisfaction of SSC delivery, the provider's response to client needs and clients' comfort with providers Around 80% of clients reported their cognitive and behavioral control over AOD use and criminal conduct had improved during SSC The accompanying Participant's Workbook to the SSC is written to engage clients and encourage active participation in treatment and responsible living: Phase I: Challenge to Change: Building Knowledge and Skills for Responsible Living Phase II: Commitment to Change: Strengthening Skills for Self-Improvement, Change, and Responsible Living Phase III: Taking Ownership of Change: Lifestyle Balance and Healthy Living

📒The Immune System ✍ Carol Ballard

The Immune System Book PDF
✏Book Title : The Immune System
✏Author : Carol Ballard
✏Publisher :
✏Release Date : 2009
✏Pages : 48
✏ISBN : 0431157499
✏Available Language : English, Spanish, And French

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✏The Immune System Book Summary : Discusses the immune system; including the cells, tissues, and organs involved in its function; and explains its role in keeping the body free from illness and disease.

Cells Of The Immune System Book PDF
✏Book Title : Cells of the Immune System
✏Author : Ota Fuchs
✏Publisher : BoD – Books on Demand
✏Release Date : 2020-05-13
✏Pages : 246
✏ISBN : 9781789855838
✏Available Language : English, Spanish, And French

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✏Cells of the Immune System Book Summary : The cells of the immune system are lymphocytes (T-cells, B-cells and NK (natural killer) cells), neutrophils, eosinophils, and monocytes/macrophages. This book is an overview of some types of these cells and their role in recognizing and/or reacting against foreign material. The immune system is characterized by collaboration between cells and proteins. The development of all cells of the immune system begins in the bone marrow with a hematopoietic stem cell. Two chapters deal with neutrophils, three chapters with T-cells, four chapters with eosinophils, and other chapters review the immunomodulation of macrophages, the role of transcription factor KLF4 in regulating plasticity of myeloid-derived suppressor cells, immune reconstitution after allogeneic hematopoietic stem cell transplantation, and role of sorption detoxification in the therapy of acute radiation sickness.

📒The Immune System Cure ✍ Lorna A. VanderHaeghe

The Immune System Cure Book PDF
✏Book Title : The Immune System Cure
✏Author : Lorna A. VanderHaeghe
✏Publisher : CIMA Publishing
✏Release Date : 2001
✏Pages : 242
✏ISBN : 1903116368
✏Available Language : English, Spanish, And French

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✏The Immune System Cure Book Summary :

Interaction Of Nanomaterials With The Immune System Book PDF
✏Book Title : Interaction of Nanomaterials with the Immune System
✏Author : James C. Bonner
✏Publisher : Springer
✏Release Date : 2020-01-31
✏Pages : 223
✏ISBN : 3030339610
✏Available Language : English, Spanish, And French

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✏Interaction of Nanomaterials with the Immune System Book Summary : This book covers the latest information related to understanding immune responses to engineered nanomaterials (ENMs). Many ENMs used in both the consumer and biomedical fields have been reported to elicit adverse immune responses ranging from innate immune responses such as complement activation to changes in adaptive immunity that influence pathogen responses and promote disease states such as asthma. Interaction of Nanomaterials with the Immune System covers the most up to date information on our understanding of immune responses to ENMs across a wide range of topics including innate immunity, allergic immune responses, adaptive provides the reader with (1) up to date understanding of immune responses to ENMs; (2) current testing methods; and (3) appropriate models including alternative testing strategies for evaluating immunotoxicity of ENMs.

📒Immune System ✍ Grace Hansen

Immune System Book PDF
✏Book Title : Immune System
✏Author : Grace Hansen
✏Publisher : Abdo Kids Jumbo
✏Release Date : 2018-12-15
✏Pages : 24
✏ISBN : 9781532182846
✏Available Language : English, Spanish, And French

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✏Immune System Book Summary : This titles teaches readers about the immune system. Readers will learn about the importance of the immune system and the main defenses their body has against pathogens, like B cell, antibodies, and T cells. Aligned to Common Core Standards and correlated to state standards. Abdo Kids Jumbo is an imprint of Abdo Kids, a division of ABDO.

How The Immune System Recognizes Self And Nonself Book PDF
✏Book Title : How the Immune System Recognizes Self and Nonself
✏Author : Daisuke Kitamura
✏Publisher : Springer Science & Business Media
✏Release Date : 2008-04-08
✏Pages : 251
✏ISBN : 4431738843
✏Available Language : English, Spanish, And French

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✏How the Immune System Recognizes Self and Nonself Book Summary : How do you discriminate yourself from other people? This question must sound odd to you since you easily recognize others at a glance and, without any effort, would not mistake them for yourself. However, it is not always easy for some people to discriminate themselves from others. For example, patients with schi- phrenia often talk with “others” living inside themselves. Thus it is likely that n- mally your brain actively recognizes and remembers the information belonging to yourself and discriminates it from the information provided by others, although you are not conscious of it. This brain function must have been particularly important for most animals to protect their lives from enemies and for species to survive through evolution. Similarly, higher organisms have also acquired their immune system through evolution that discriminates nonself pathogens and self-body to protect their lives from pathogens such as bacteria or viruses. The brain system may distinguish integrated images of self and nonself created from many inputs, such as vision, sound, smell, and others. The immune system recognizes and distinguishes a variety of structural features of self and nonself components. The latter actually include almost everything but self: for example, bacteria, viruses, toxins, pollens, chemicals, transplanted organs, and even tumor cells derived from self-tissue. To this end the immune system recruits different kinds of immune cells, such as B and T lymphocytes, natural killer (NK) cells, dendritic cells, and macrophages.

Design Principles For The Immune System And Other Distributed Autonomous Systems Book PDF
✏Book Title : Design Principles for the Immune System and Other Distributed Autonomous Systems
✏Author : Lee A. Segel
✏Publisher : Oxford University Press
✏Release Date : 2001-06-14
✏Pages : 428
✏ISBN : 0198031343
✏Available Language : English, Spanish, And French

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✏Design Principles for the Immune System and Other Distributed Autonomous Systems Book Summary : Design Principles for the Immune System and Other Distributed Autonomous Systems is the first book to examine the inner workings of such a variety of distributed autonomous systems--from insect colonies to high level computer programs to the immune system. It offers insight into the fascinating world of these systems that emerge from the interactions of seemingly autonomous components and brings us up-to-date on the state of research in these areas. Using the immune system and certain aspects of its functions as a primary model, this book examines many of the most interesting and troubling questions posed by complex systems. How do systems choose the right set of agents to perform appropriate actions with appropriate intensities at appropriate times? How in the immune system, ant colonies and metabolic networks does the diffusion and binding of a large variety of chemicals to their receptors permit coordination of system action? What advantages drive the various systems to complexity, and by what mechanisms do the systems cope with the tendency toward unwieldiness and randomness of large complex systems?

📒The Immune System ✍ Peter Parham

The Immune System Book PDF
✏Book Title : The Immune System
✏Author : Peter Parham
✏Publisher : Garland Science
✏Release Date : 2005
✏Pages : 18
✏ISBN : 0815340931
✏Available Language : English, Spanish, And French

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✏The Immune System Book Summary : The new edition of The Immune System has been thoroughly updated throughout. This book includes increased emphasis on genetics, the human immune system and the treatment of innate immunity, particularly the mucosal system.

The Role Of The Immune System In The Pathogenesis Of Diabetic Complications Book PDF
✏Book Title : The role of the immune system in the pathogenesis of diabetic complications
✏Author : Gabriel Virella
✏Publisher : Frontiers E-books
✏Release Date : 2014-12-03
✏Pages :
✏ISBN : 9782889193523
✏Available Language : English, Spanish, And French

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✏The role of the immune system in the pathogenesis of diabetic complications Book Summary : The main causes of morbidity and mortality in diabetes are macrovasular and microvascular complications, including atherosclerosis, nephropathy, and retinopathy. As the definition of atherosclerosis as a chronic, smoldering, inflammatory disease has gained general acceptance, the attention of researchers has focused on the triggers of chronic vascular inflammation. The oxidation and other forms of modification of lipids and lipoproteins have emerged as a major pathogenic factor in atherosclerosis, with a significant interaction with the immune system. Modified lipoproteins by themselves are proinflammatory through the activation of the innate immune system as a consequence of the interaction with scavenger receptors and/or toll-like receptors expressed by a variety of cell types, including phagocytic cells and dendritic cells. A variety of modified forms of LDL (mLDL), including oxidized, malondialdehyde-modified, and Advanced Glycation End-product-modified LDL induce autoimmune responses in humans. Those modifications seem enhanced in diabetes, and the progression of atherosclerosis is accelerated in diabetic patients. The immune response to all forms of mLDL results in both activation of T cells in the arterial wall and in an autoimmune response characterized by the formation of IgG antibodies. Both arms of the immune response are believed to play a role in vascular inflammation. While the cell response is likely to activate resident macrophages, the humoral immune response results in the production of IgG antibodies that bind to specific epitopes in modified forms of LDL, generate immune complexes both intra- and extravascularly, and those complexes are able to activate the classical pathway of the complement system as well as phagocytic cells via Fc? receptors. In vitro studies suggest that the pro-inflammatory activity of immune complexes containing mLDL is several-fold higher than that of the modified LDL molecules by themselves. Clinical studies have provided significant support to the pathogenic role of immune complexes containing modified LDL in the development of atherosclerotic complications in patients with both type 1 and type 2 diabetes. At the same time, there is increasing evidence that the formation of immune complexes containing modified forms of LDL may also be involved in the pathogenesis of diabetic nephropathy and retinopathy. These are areas in which more research is needed to fully understand the pathogenic mechanisms activated by those immune complexes. Of interest is the fact that animal models have suggested the possibility of modifying the adaptive humoral immune response in ways that would result in slowing down, and perhaps prevent, the atherosclerotic process. This possibility is sufficiently alluring as to justify increased research efforts, both in animal models (including diabetic animals) and translational clinical studies. The manipulation of the T regulatory population is another area of potential translational impact, which has hardly been explored. Indeed at this point of time, what seems to be a high priority is an increased and open interchange of information among investigators, trying to reach a better general understanding and integration of knowledge generated from a variety of approaches and perspectives. This Research Topic provided an optimal platform for this open interchange of information. We encouraged interested scientists to submit mini-reviews, methods papers, review articles, perspectives and original research articles covering this topic in all its diversity to facilitate the communication of perspectives and new information between scientists interested in understanding the multiple implications of the involvement of the immune system in the pathogenesis of diabetic complications.

A Holistic Protocol For The Immune System Book PDF
✏Book Title : A Holistic Protocol for the Immune System
✏Author : Scott J. Gregory
✏Publisher : Progressive Press
✏Release Date : 1995
✏Pages : 126
✏ISBN : 093085229X
✏Available Language : English, Spanish, And French

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✏A Holistic Protocol for the Immune System Book Summary :

The Evolution Of The Immune System Book PDF
✏Book Title : The Evolution of the Immune System
✏Author : Davide Malagoli
✏Publisher : Academic Press
✏Release Date : 2016-07-21
✏Pages : 384
✏ISBN : 9780128020135
✏Available Language : English, Spanish, And French

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✏The Evolution of the Immune System Book Summary : The Evolution of the Immune System: Conservation and Diversification is the first book of its kind that prompts a new perspective when describing and considering the evolution of the immune system. Its unique approach summarizes, updates, and provides new insights on the different immune receptors, soluble factors, and immune cell effectors. Helps the reader gain a modern idea of the evolution of the immune systems in pluricellular organisms Provides a complete overview of the most studied and hot topics in comparative and evolutionary immunology Reflects the organisation of the immune system (cell-based, humoral [innate], humoral [adaptive]) without introducing further and misleading levels of organization Brings concepts and ideas on the evolution of the immune system to a wide readership

Immunobiotics Interactions Of Beneficial Microbes With The Immune System Book PDF
✏Book Title : Immunobiotics Interactions of Beneficial Microbes with the Immune System
✏Author : Julio Villena
✏Publisher : Frontiers Media SA
✏Release Date : 2018-01-26
✏Pages :
✏ISBN : 9782889453825
✏Available Language : English, Spanish, And French

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✏Immunobiotics Interactions of Beneficial Microbes with the Immune System Book Summary : The term “immunobiotics” has been proposed to define microbial strains able to beneficially regulate the mucosal immune system. Research in immunobiotics has significantly evolved as researchers employed cutting-edge technologies to investigate the complex interactions of these beneficial microorganisms with the immune system. During the last decade, our understanding of immunobiotics-host interaction was profoundly transformed by the discovery of microbial molecules and host receptors involved in the modulation of gut associated immune system, as well as the systemic and distant mucosal immune systems. In recent years, there has been a substantial increase in the number of reports describing the beneficial effects of immunobiotics in diseases such as intestinal and respiratory infections, allergy, inflammatory bowel disease, obesity, immunosuppression, and several other immune-mediated conditions. Evidence is also emerging of immunobiotics related molecules with immunomodulatory functions leading to the production of pharmabiotics, which may positively influence human or animal health. Therefore, research in immunobiotics continue to contribute not only to food but also medical and pharmaceutical fields. The compilation of research articles included in this ebook should help reader to have an overview of the recent advances in immunobiotics.

📒The Immune System ✍ Rodney Langman

The Immune System Book PDF
✏Book Title : The immune system
✏Author : Rodney Langman
✏Publisher : Elsevier
✏Release Date : 2014-07-23
✏Pages : 256
✏ISBN : 9780323158855
✏Available Language : English, Spanish, And French

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✏The immune system Book Summary : 9780124365858 The Immune System: Evolutionary Principle Guide our Understanding of this Complex Biological Defense System provides the conceptual framework of immunology and the evolutionary events that have shaped the understanding of the immune system. This book contains 10 chapters, and begins with a brief discussion on the evolutionary aspects of immunology considering the Darwinian principles of evolution. This topic is followed by a presentation of the selective pressures that are likely to have molded the immune system, as well as the laws of the immune system and their corollaries concerning host defense mechanism. The subsequent chapters are devoted to cellular components of the immune system, including the B and T cells, immunoglobulins, interleukins, major histocompatibility complex, and lymphoid organs. The structural information and the evolutionary events in these immune system components are provided. A chapter focuses on the evolutionary successful components of the inflammatory system. The concluding chapter deals with the conflicting conventional wisdoms on functional immune system. This book will prove useful to immunologists and research workers in immunology and related fields.