The Hypothalamus Pituitary Adrenal Axis

The Role Of The Amygdala In Regulating The Hypothalamic Pituitary Adrenal Axis Book PDF
✏Book Title : The Role of the Amygdala in Regulating the Hypothalamic Pituitary Adrenal Axis
✏Author : Joseph Weidenfeld
✏Publisher :
✏Release Date : 2017
✏Pages :
✏ISBN : OCLC:1154173729
✏Available Language : English, Spanish, And French

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✏The Role of the Amygdala in Regulating the Hypothalamic Pituitary Adrenal Axis Book Summary : We investigated the regulatory role of the amygdala upon the function of the hypothalamic-pituitary-adrenal (HPA) axis as measured by median eminence corticotrophin releasing hormone (CRH) content and serum levels of adrenocorticotrophic hormone (ACTH) and corticosterone. Our findings showed that (1) lesions of the central amygdala inhibited the HPA axis responses to a variety of stressful stimuli. (2) Depletion of norepinephrine or serotonin in the amygdala and hypothalamus and local injections of norepinephrine and serotonin receptor antagonists into the central amygdala inhibited the HPA axis responses to neural stress. Norepinephrine and serotonin agonists injected into the amygdala caused an increase in HPA axis activity. The activation of the amygdala facilitated the in vivo release of serotonin from the paraventricular nucleus following electrical stimulation of the brainstem raphe nuclei. (3) Electrical stimulation of the amygdala impaired the glucocorticoid negative feedback action following neural stressful stimuli probably via a decrease in hippocampal corticosteroid receptors.

Psychoneuroendocrinology Of Depression Book PDF
✏Book Title : Psychoneuroendocrinology of Depression
✏Author : Charles B. Nemeeroff
✏Publisher :
✏Release Date : 1993
✏Pages : 36
✏ISBN : NWU:35558003866080
✏Available Language : English, Spanish, And French

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✏Psychoneuroendocrinology of Depression Book Summary :

Interactions Between Feeding And The Hypothalamic Pituitary Adrenal Axis Book PDF
✏Book Title : Interactions Between Feeding and the Hypothalamic pituitary adrenal Axis
✏Author : Edward Simon Hanson
✏Publisher :
✏Release Date : 1997
✏Pages : 348
✏ISBN : UCAL:X66943
✏Available Language : English, Spanish, And French

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✏Interactions Between Feeding and the Hypothalamic pituitary adrenal Axis Book Summary :

Stress The Hypothalamic Pituitary Adrenal Axis And Immune Function In Adult Male Rhesus Macaques Macaca Mulatta  Book PDF
✏Book Title : Stress the hypothalamic pituitary adrenal axis and immune function in adult male rhesus macaques Macaca mulatta
✏Author : Nicole Maninger
✏Publisher :
✏Release Date : 2005
✏Pages : 162
✏ISBN : UCAL:X72576
✏Available Language : English, Spanish, And French

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✏Stress the hypothalamic pituitary adrenal axis and immune function in adult male rhesus macaques Macaca mulatta Book Summary :

Hypothalamic Pituitary Adrenal Axis Dysregulation Body Mass Index Growth Trajectories And Obesity In Females With Histories Of Childhood Sexual Abuse And Nonabused Comparisons  Book PDF
✏Book Title : HYPOTHALAMIC PITUITARY ADRENAL AXIS DYSREGULATION BODY MASS INDEX GROWTH TRAJECTORIES AND OBESITY IN FEMALES WITH HISTORIES OF CHILDHOOD SEXUAL ABUSE AND NONABUSED COMPARISONS
✏Author : Jacinda Changhui Li
✏Publisher :
✏Release Date : 2019
✏Pages :
✏ISBN : OCLC:1107094106
✏Available Language : English, Spanish, And French

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✏HYPOTHALAMIC PITUITARY ADRENAL AXIS DYSREGULATION BODY MASS INDEX GROWTH TRAJECTORIES AND OBESITY IN FEMALES WITH HISTORIES OF CHILDHOOD SEXUAL ABUSE AND NONABUSED COMPARISONS Book Summary : Obesity disproportionately burdens females, thereby perpetuating intergenerational obesity and numerous other health problems in offspring. Thus, efforts to treat and prevent obesity in females is critical for combating the obesity epidemic. Effective intervention requires improving understanding about who is most vulnerable and what mechanisms explain their elevated risk. Childhood sexual abuse (CSA) has been established as a powerful risk factor for obesity in females, yet the potential mechanisms that explain the elevated risk remain unclear. Consistent with the literature on allostatic load, dysregulation of the stress response system through early-life traumatic stressof which CSA is arguably one of the most severe formshas been implicated in obesity. Specifically, hypothalamic-pituitary-adrenal (HPA) axis dysregulation, defined as initially-elevated cortisol levels followed by attenuated rates of growth in these levels over time, has been identified as a potential mechanism for excessive weight gain and obesity in individuals who were exposed to traumatic stress. The existing literature on the relationship between HPA axis dysregulation and obesity consists primarily of animal studies or short-term, laboratory-based human experiments. Thus, the role of long-term HPA axis dysregulation in obesity in humans remains inconclusive. Furthermore, there is a paucity of studies that formally test the extent to which HPA axis dysregulation accounts for excessive weight gain and obesity in females with objectively-confirmed CSA exposure, while taking into account potential confounding factors such as race/ethnicity, parity status, depression, and disordered eating. This dissertation addressed the existing gaps in the literature by investigating the long-term associations between HPA axis dysregulation, body mass index (BMI) growth trajectories, and obesity in sexually abused and nonabused females. It capitalized upon the unique cross-sequential cohort data of the Female Growth and Development Study (FGDS; PI: Noll), which prospectively followed a diverse sample of 173 females with court-substantiated CSA and demographically-matched nonabused comparisons from childhood into early adulthood. This dissertation examined (1) the associations between HPA axis dysregulation and BMI growth trajectories across development for females in general; (2) differential associations between HPA axis dysregulation and BMI growth trajectories for abused and nonabused females; and (3) the extent to which HPA axis dysregulation accounted for the effects of CSA on BMI growth rates and obesity status.Indicators of HPA axis dysregulation were derived by extracting the intercept and linear slope parameters from multilevel growth models of serum nonstress cortisol levels across development. A separate set of multilevel growth models estimated the effect of HPA axis dysregulation indicators on the intercept and linear slope parameters of BMI growth trajectories across development. In addition, growth models examined whether CSA group membership altered the effects of HPA axis dysregulation indicators on BMI growth trajectories. The extent to which HPA axis dysregulation indicators accounted for the effects of CSA on accelerated BMI growth rates was evaluated by the extent of reduction in the CSA effect on the linear slope parameter of BMI growth trajectories after accounting for HPA axis dysregulation indicators. Indirect effects analysis via Bootstrap Sobel Test examined the indirect paths of CSA on adulthood obesity through the average nonstress cortisol levels in childhood, adolescence, or in adulthood. All models controlled for potential confounds.Results of multilevel growth models showed that HPA axis dysregulation was associated with accelerated BMI growth rates across development, indicating a greater risk for excessive weight gain from childhood into early adulthood. The association between HPA axis dysregulation and BMI growth rates was stronger for the CSA group than for comparisons, indicating that abused females were more vulnerable to the effect of HPA axis dysregulation on excessive weight gain than were nonabused females. HPA axis dysregulation accounted for a significant portion of the effects of CSA on accelerated BMI growth rates. Results of indirect effects analyses showed that lower average levels of nonstress cortisol in adulthood accounted for a significant portion of the effect of CSA exposure on elevated obesity rates in adulthood. These findings provide evidence in support of theories that implicate HPA axis dysregulation as a potential mechanism for excessive weight gain and elevated risks for obesity for CSA females.Supplemental analyses examined the association between HPA axis dysregulation and BMI growth trajectories through alternative methods. Tests of the association between HPA axis dysregulation and BMI growth trajectories across time since abuse disclosure reinforced the findings from the primary analyses that had examined this association across development. Additionally, variability in nonstress cortisol levels was associated with accelerated BMI growth rates across development. Subsets of the CSA group that had abuse onset in late childhood/early-adolescence, abuse duration of single incident to one year, or abuse perpetrated by primary father figure showed the strongest association between HPA axis dysregulation and obesity-related outcomes. These findings help to identify the characteristics of high-risk CSA subgroups.This dissertation contributes to the growing body of work emerging from the FGDS to investigate the long-term consequences of CSA on female development across multiple levels of human functioning. By simultaneously examining the long-term trajectories of HPA axis dysregulation and of BMI while accounting for potential confounds, this dissertation also contributes to the literature on the putative role of HPA axis dysregulation in excessive weight gain and obesity. This dissertation also presented formal tests of the extent to which HPA axis dysregulation accounted for the effect of CSA exposure on excessive weight gain over time and elevated risk for obesity in adulthood. Findings help to advance trauma-informed obesity intervention models for females with histories of CSA as well as enhanced intervention and public health policy approaches for individuals in the general population who may also exhibit traumatic stress-related HPA axis dysregulation.

Mechanisms Regulating Inhibition Of The Hypothalamic Pituitary Adrenal Axis During Restriction Induced Drinking In The Rat Book PDF
✏Book Title : Mechanisms Regulating Inhibition of the Hypothalamic pituitary adrenal Axis During Restriction induced Drinking in the Rat
✏Author : Cheryl Wotus
✏Publisher :
✏Release Date : 2003
✏Pages : 318
✏ISBN : MINN:31951P01037651D
✏Available Language : English, Spanish, And French

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✏Mechanisms Regulating Inhibition of the Hypothalamic pituitary adrenal Axis During Restriction induced Drinking in the Rat Book Summary :

Hypothalamic Pituitary Adrenal Axis Functioning In Disruptive Behavior Disorders Book PDF
✏Book Title : Hypothalamic Pituitary Adrenal Axis Functioning in Disruptive Behavior Disorders
✏Author : Laura M. Hall
✏Publisher :
✏Release Date : 2002
✏Pages : 242
✏ISBN : OCLC:51393390
✏Available Language : English, Spanish, And French

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✏Hypothalamic Pituitary Adrenal Axis Functioning in Disruptive Behavior Disorders Book Summary :

The Hypothalamus Pituitary Adrenal Axis Book PDF
✏Book Title : The Hypothalamus Pituitary Adrenal Axis
✏Author :
✏Publisher : Elsevier
✏Release Date : 2008-09-12
✏Pages : 416
✏ISBN : 0080559360
✏Available Language : English, Spanish, And French

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✏The Hypothalamus Pituitary Adrenal Axis Book Summary : The hypothalamic-pituitary-adrenal axis controls reactions to stress and regulates various body processes such as digestion, the immune system, mood and sexuality, and energy usage. This volume focuses on the role it plays in the immune system and provides substantive experimental and clinical data to support current understanding in the field, and potential applications of this knowledge in the treatment of disease. * Evidence presented in this book suggests that the nervous, endocrine, and immune systems form the Neuroendoimmune Supersystem, which integrates all the biological functions of higher organisms both in health and disease for their entire life cycle. * Contributors include both the scientists who initiated the work on the HPA axis and on the autonomic nervous system, and those who joined the field later.

Electroacupuncture Regulate Hypothalamic Pituitary Adrenal Axis And Enhance Hippocampal Serotonin System In A Rat Model Of Depression Book PDF
✏Book Title : Electroacupuncture Regulate Hypothalamic pituitary adrenal Axis and Enhance Hippocampal Serotonin System in a Rat Model of Depression
✏Author :
✏Publisher :
✏Release Date : 2016
✏Pages :
✏ISBN : OCLC:1052035061
✏Available Language : English, Spanish, And French

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✏Electroacupuncture Regulate Hypothalamic pituitary adrenal Axis and Enhance Hippocampal Serotonin System in a Rat Model of Depression Book Summary : Highlights: In the current study, we used forced swimming test and open-field test to determine whether electroacupuncture (EA) affects chronic unpredictable mild stress (CUMS)-induced depression-like behavior. Further, we discussed the impacts of EA treatment on the regulation of hypothalamic–pituitary–adrenal (HPA) axis and hippocampal serotonin (5-hydroxytryptamine, 5-HT) system. Our results show that EA treatment could ameliorate CUMS-induced behavioral symptoms, stabilize the HPA axis and increase hippocampal 5-HT/5-HT1AR. The data provides preliminary evidence that EA could relieve behavioral symptoms by modulating HPA axis and enhancing hippocampal serotonin system in CUMS rats. This finding supports the clinical use of EA in treatment of depression disorder and may initiate a discussion on the involvement of HPA axis and hippocampal serotonin system in anti-depressive effect of EA. Abstract: Hypothalamic–pituitary–adrenal (HPA) axis has been implicated in the pathogenesis of depression. Dysfunction of the hippocampal serotonin (5-hydroxytryptamine, 5-HT) system has been shown to be a key factor in depression. There is growing evidence that electro-acupuncture (EA) has antidepressant-like effect. However, the effect of EA on HPA axis and hippocampal serotonin system remains unknown. In our study, we investigated the antidepressant-like effect and mechanism of EA for depression rat models. Depression in rats was induced by chronic unpredictable mild stress (CUMS). EA treatment was administered once daily to CUMS rats for 14 days. The acupoints (ST36, bilateral and CV4) were selected. Untreated CUMS rats and normal rats were used as controls. Behavioral tests including forced swim test and open-field test were performed to evaluate the antidepressant effects of EA treatment. Hypothalamic corticotropin-releasing hormone (CRH) mRNA, plasma adrenocorticotropic hormone (ACTH) and corticosterone (CORT) were estimated as indices of HPA axis activity. Enzyme linked immunosorbent assay (ELISA) was performed to determine the concentrations of 5-HT in the hippocampus. Real-time PCR(RT-PCR)and Western blot were respectively used to detect the mRNA and protein levels of 5-hydroxytryptamine 1A receptor (5-HT1AR) in the hippocampus. Our results showed that EA treatment reversed the behavioral deficiency induced by CUMS in rats. EA treatment decreased CRH mRNA expression in the hypothalamic, and ACTH and CORT level in plasma, and markedly increased 5-HT concentration, 5-HT1AR (mRNA and protein) expression in the hippocampus. These results indicated that EA treatment could act on depression by modulating HPA axis and enhancing hippocampal 5-HT/5-HT1AR in CUMS Rats.

Hypothalamic Pituitary Adrenal Hpa Axis Related Genetic Variants Influence The Stress Response Book PDF
✏Book Title : Hypothalamic pituitary adrenal HPA Axis related Genetic Variants Influence the Stress Response
✏Author : Ting Li-Tempel
✏Publisher :
✏Release Date : 2020
✏Pages :
✏ISBN : OCLC:1156852436
✏Available Language : English, Spanish, And French

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Cocaine Self Administration And Hypothalamic Pituitary Adrenal Hpa Axis Activity In Rhesus Monkeys Book PDF
✏Book Title : Cocaine Self Administration and Hypothalamic pituitary adrenal HPA Axis Activity in Rhesus Monkeys
✏Author : Jillian Helen Broadbear
✏Publisher :
✏Release Date : 1999
✏Pages :
✏ISBN : UOM:39015043222283
✏Available Language : English, Spanish, And French

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✏Cocaine Self Administration and Hypothalamic pituitary adrenal HPA Axis Activity in Rhesus Monkeys Book Summary :

The Hypothalamic Pituitary Adrenal Axis In Health And Disease Book PDF
✏Book Title : The Hypothalamic Pituitary Adrenal Axis in Health and Disease
✏Author : Eliza B. Geer
✏Publisher : Springer
✏Release Date : 2016-12-01
✏Pages : 327
✏ISBN : 9783319459509
✏Available Language : English, Spanish, And French

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✏The Hypothalamic Pituitary Adrenal Axis in Health and Disease Book Summary : Cushing ́s syndrome is a rare disorder that is associated with many co-morbidities such as systemic hypertension, diabetes, osteoporosis, impaired immune function, and psychiatric disease, all of which severely reduce quality of life and life expectancy. This book reviews the role of cortisol in the human body, focusing on the effects of excess cortisol due to Cushing’s syndrome as well as the role of the HPA axis in metabolism, inflammation, and neuropsychiatric function. The volume will cover basic mechanistic data, clinical outcomes data, and novel therapies. Also discussed are everything from abnormalities of the HPA axis, to the role of the HPA axis in the development of neuropsychiatric disorders and metabolic disorders, to new definitions of Cushing’s remission and recurrence. The Hypothalamic Pituitary Adrenal Axis in Health and Disease will provide a comprehensive and multi-disciplinary review of the pathophysiology and outcomes of excess cortisol in the human body and brain as well as the role of the HPA axis in other disease states.

A Psychobiological Perspective On The Association Of Common Glucocorticoid Receptor Gene Polymorphisms With Hypothalamus Pituitary Adrenal Axis Regulation Book PDF
✏Book Title : A Psychobiological Perspective on the Association of Common Glucocorticoid Receptor Gene Polymorphisms with Hypothalamus Pituitary Adrenal Axis Regulation
✏Author : Robert Kumsta
✏Publisher : Cuvillier Verlag
✏Release Date : 2007-02-17
✏Pages : 156
✏ISBN : 9783736921559
✏Available Language : English, Spanish, And French

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✏A Psychobiological Perspective on the Association of Common Glucocorticoid Receptor Gene Polymorphisms with Hypothalamus Pituitary Adrenal Axis Regulation Book Summary : The stress response has evolved as a highly adaptive reaction that ensures survival when an organism is confronted with physiological or psychological challenge. However, when occurring chronically, these responses can ultimately promote or sustain disease processes. One important stress responsive system is the hypothalamus-pituitary-adrenal (HPA) axis, a hierarchical hormonal system, which mediates the endocrine stress response. The glucocorticoid receptor (GR) plays a central role in the HPA axis regulation. Experimental work presented in this thesis is intended to contribute to a further understanding of the influence of genetic factors on the functioning of the HPA axis. The relative contributions of genetic variation of the GR on HPA axis regulation under psychosocial stress, on glucocorticoid sensitivity in three target tissues and on working memory performance were investigated. The characterization of HPA axis response phenotypes in individuals carrying different GR genotypes can be a first step in the identification of individuals who are vulnerable to or protected against the development of stress related disorders.

Cckergic System Hypothalamus Pituitary Adrenal Hpa Axis And Early Life Stress Els  Book PDF
✏Book Title : CCKergic System Hypothalamus Pituitary Adrenal HPA Axis and Early Life Stress ELS
✏Author : Mingxi Tang
✏Publisher :
✏Release Date : 2012
✏Pages : 1
✏ISBN : OCLC:1163807854
✏Available Language : English, Spanish, And French

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✏CCKergic System Hypothalamus Pituitary Adrenal HPA Axis and Early Life Stress ELS Book Summary : CCKergic System, Hypothalamus-Pituitary-Adrenal (HPA) Axis, and Early-Life Stress (ELS).

Effects Of Maternal Endotoxin Treatment On Offspring Hypothalamic Pituitary Adrenal Axis And Fever Response Book PDF
✏Book Title : Effects of Maternal Endotoxin Treatment on Offspring Hypothalamic pituitary adrenal Axis and Fever Response
✏Author : University of Guelph. Department of Animal & Poultry Science
✏Publisher :
✏Release Date : 2008
✏Pages : 113
✏ISBN : 0494418192
✏Available Language : English, Spanish, And French

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✏Effects of Maternal Endotoxin Treatment on Offspring Hypothalamic pituitary adrenal Axis and Fever Response Book Summary :

The Role Of The Androgen Receptor In Anxiety Related Behaviors The Hypothalamic Pituitary Adrenal Axis And Sensorimotor Gating Book PDF
✏Book Title : The Role of the Androgen Receptor in Anxiety related Behaviors the Hypothalamic Pituitary Adrenal Axis and Sensorimotor Gating
✏Author : Damian Zuloaga
✏Publisher :
✏Release Date : 2008
✏Pages : 356
✏ISBN : MSU:31293030624492
✏Available Language : English, Spanish, And French

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✏The Role of the Androgen Receptor in Anxiety related Behaviors the Hypothalamic Pituitary Adrenal Axis and Sensorimotor Gating Book Summary :

Individual Differences In The Activation And Regulation Of The Limbic Hypothalamic Pituitary Adrenal Axis After Stress Book PDF
✏Book Title : Individual Differences in the Activation and Regulation of the Limbic hypothalamic pituitary adrenal Axis After Stress
✏Author : Nestor L. Lopez
✏Publisher :
✏Release Date : 2005
✏Pages :
✏ISBN : UOM:39015062470367
✏Available Language : English, Spanish, And French

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✏Individual Differences in the Activation and Regulation of the Limbic hypothalamic pituitary adrenal Axis After Stress Book Summary :

The Pituitary Gland And Adrenal Glands Book PDF
✏Book Title : The Pituitary Gland and Adrenal Glands
✏Author : Noémi Barta
✏Publisher : Nova Science Publishers
✏Release Date : 2020
✏Pages : 222
✏ISBN : 1536176060
✏Available Language : English, Spanish, And French

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✏The Pituitary Gland and Adrenal Glands Book Summary : "In The Pituitary Gland and Adrenal Glands: New Research, the authors first discuss pituicytomas, rare primary glial neoplasms that arise in the neurohypophysis (or posterior portion) of the pituitary gland. They typically present with signs and symptoms of a slow growing, non-hormonally active mass of the sellar and suprasellar region, compressing adjacent structures. Following this, the clinical and pathologic features of spindle cell oncocytomas are discussed. Spindle cell oncocytomas are rare tumors, accounting for less than 0.5% of sellar masses. Tumors typically present in adults and most commonly manifest with visual disturbances and pituitary hypofunction. Additionally, the authors review the clinical and pathological features of gangliocytomas, rare benign tumors of the neuroaxis. They are most commonly seen in children and young adults, and most often arise in the cerebellum as part of Cowden's disease, or in the sellar region. The clinicopathologic features of granular tumors, rare neoplasms that most commonly arise in the neurohypophysis or posterior portion of the pituitary gland, are also discussed. This compilation goes on to examine the adrenal glands, paired structures located superior to the kidneys in the retroperitoneal space. Mineralocorticoids, glucocorticoids and adrenal androgens are synthesized respectively in the zona glomerulosa, zona fasciculatis and zona reticularis that make up the cortex, while the inner adrenal medulla produces the catecholamines and peptides. The risk of developing adrenal insufficiency among glucocorticoid users is assessed, and risk factors are identified. Glucocorticoids are widely used for the treatment of various inflammatory conditions and malignancies, as well as after organ transplantation. The closing study explores hypothalamic-pituitary-adrenal axis activation, a potent and complex response to heat stress in domestic livestock. The hypothalamic-pituitary-adrenal axis is activated during stress, which leads to the secretion of cortisol and aldosterone from the adrenal gland"--

Psychosocial Stress And Cardiovascular Disease Book PDF
✏Book Title : Psychosocial Stress and Cardiovascular Disease
✏Author : A. L. Ronaldson
✏Publisher :
✏Release Date : 2017
✏Pages :
✏ISBN : OCLC:1129903633
✏Available Language : English, Spanish, And French

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The Effects Of Cortisol On The Development Of The Fetal Hypothalamic Pituitary Adrenal Axis Book PDF
✏Book Title : The Effects of Cortisol on the Development of the Fetal Hypothalamic pituitary adrenal Axis
✏Author :
✏Publisher :
✏Release Date : 1999
✏Pages :
✏ISBN : OCLC:654164387
✏Available Language : English, Spanish, And French

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✏The Effects of Cortisol on the Development of the Fetal Hypothalamic pituitary adrenal Axis Book Summary :

Hypothalamus Pituitary Adrenal Axis Activity And Cognitive Functioning In Older Adults Book PDF
✏Book Title : Hypothalamus Pituitary Adrenal axis Activity and Cognitive Functioning in Older Adults
✏Author :
✏Publisher :
✏Release Date : 2018
✏Pages :
✏ISBN : OCLC:1052038127
✏Available Language : English, Spanish, And French

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✏Hypothalamus Pituitary Adrenal axis Activity and Cognitive Functioning in Older Adults Book Summary : Highlights: HPA-axis activity is not consistently associated with cognitive functioning in non-depressed older adults. HAP-axis activity is not associated with cognitive functioning in depressed older adults. Cortisol is not likely to be a major factor contributing to poorer cognitive functioning in depressed older adults. Abstract: Inconsistent results are found in the involvement of the Hypothalamus-Pituitary-Adrenal (HPA)-axis in cognitive functioning. This study examined the association between various saliva cortisol measures (the 1-h awakening cortisol, evening cortisol, diurnal change, and cortisol suppression) and cognitive functioning (episodic memory, processing speed, interference control, and working memory). Participants were older adults, between 60 and 93 years with (N=328) and without (N=119) a depressive disorder from the Netherlands Study of Depression in Older adults. No significant associations between cortisol and cognitive functioning were observed in the total sample. Only in non-depressed older adults, higher total cortisol secretion over the first hour after awakening and worse episodic memory, higher cortisol levels at awakening and better working memory, and higher diurnal change and better processing speed were significantly associated. Cortisol was not associated with cognitive functioning in depressed older adults. In older adults, the association between depression and cognitive functioning is likely the consequence of other biological or psychological mechanisms.

The Hypothalamic Pituitary Adrenal Axis Revisited Book PDF
✏Book Title : The Hypothalamic pituitary adrenal Axis Revisited
✏Author : William F. Ganong
✏Publisher :
✏Release Date : 1987
✏Pages : 504
✏ISBN : 0897664450
✏Available Language : English, Spanish, And French

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Effects Of Early Childhood Trauma On Hypothalamic Pituitary Adrenal Hpa Axis Function In Patients With Chronic Fatigue Syndrome Book PDF
✏Book Title : Effects of Early Childhood Trauma on Hypothalamic pituitary adrenal HPA Axis Function in Patients with Chronic Fatigue Syndrome
✏Author :
✏Publisher :
✏Release Date : 2015
✏Pages :
✏ISBN : OCLC:1051388896
✏Available Language : English, Spanish, And French

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✏Effects of Early Childhood Trauma on Hypothalamic pituitary adrenal HPA Axis Function in Patients with Chronic Fatigue Syndrome Book Summary : Highlights: This is the first study that simultaneously investigated HPA-axis activity and reactivity in patients diagnosed with CFS. Specifically, this study investigated effects of early childhood trauma on cortisol activity as measured over a 7-day period and cortisol responses to psychosocial stress in the Trier Social Stress Test. Childhood emotional neglect is associated with reduced HPA-axis reactivity (but not with cortisol activity) in CFS. Summary: Background: There is a paucity of studies that have investigated the assumption that early childhood trauma is associated with hypothalamic–pituitary–adrenal (HPA) axis dysfunction in Chronic Fatigue Syndrome (CFS). The current study is the first to simultaneously investigate relationships among early childhood trauma, cortisol activity, and cortisol stress reactivity to psychosocial stress in a sample of well-screened CFS patients. We also examined whether self-critical perfectionism (SCP) plays a mediating role in the potential relationship between early trauma and neurobiological stress responses. Methods: A total of 40 female patients diagnosed with CFS were asked to provide morning saliva cortisol samples (after awakening, 30 min later, and 1 h later) for seven consecutive days as a measure of cortisol activity. In addition, patients were exposed to the Trier Social Stress Test, a well-validated stress test, to investigate the relationship between early childhood trauma and cortisol stress reactivity. Before the start of the study, patients completed the Childhood Trauma Questionnaire-Short form (CTQ-SF) as a measure of early childhood trauma (i.e. sexual, physical and emotional traumatic experiences). SCP was measured with the Depressive Experiences Questionnaire (DEQ). Data were analyzed by calculating several indices of cortisol secretion (i.e. Cortisol Awakening Response and Area Under the Curve). Results: There was no association between early childhood trauma and cortisol as measured over the 7-day period. However, emotional neglect was significantly negatively related to cortisol reactivity in the TSST. SCP did not significantly mediate this association. Conclusion: Findings of this study suggest that emotional neglect is associated with blunted HPA axis reactivity, congruent with the assumption that CFS may reflect loss of adaptability of the neuroendocrine stress response system in at least a subgroup of patients.

The Hypothalamic Pituitary Adrenal Axis Book PDF
✏Book Title : The Hypothalamic pituitary adrenal Axis
✏Author : Alan F. Schatzberg
✏Publisher :
✏Release Date : 1988
✏Pages : 205
✏ISBN : UOM:39015012580737
✏Available Language : English, Spanish, And French

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Chronic Morphine Treatment And Hypothalamic Pituitary Adrenal Axis Activity In Rats Book PDF
✏Book Title : Chronic Morphine Treatment and Hypothalamic pituitary adrenal Axis Activity in Rats
✏Author : Hani Houshyar
✏Publisher :
✏Release Date : 2000
✏Pages :
✏ISBN : UOM:39015049504197
✏Available Language : English, Spanish, And French

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✏Chronic Morphine Treatment and Hypothalamic pituitary adrenal Axis Activity in Rats Book Summary :

📒Maternal Fetal Neonatal Physiology ✍ Susan Tucker Blackburn

Maternal Fetal Neonatal Physiology Book PDF
✏Book Title : Maternal Fetal Neonatal Physiology
✏Author : Susan Tucker Blackburn
✏Publisher : Elsevier Health Sciences
✏Release Date : 2007
✏Pages : 777
✏ISBN : 9781416029441
✏Available Language : English, Spanish, And French

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✏Maternal Fetal Neonatal Physiology Book Summary : No further information has been provided for this title.

📒Bipolar Disorders ✍ Jair C. Soares

Bipolar Disorders Book PDF
✏Book Title : Bipolar Disorders
✏Author : Jair C. Soares
✏Publisher : CRC Press
✏Release Date : 2007-05-14
✏Pages : 440
✏ISBN : 142002115X
✏Available Language : English, Spanish, And French

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✏Bipolar Disorders Book Summary : Responding to the explosion of research on the pathophysiology and management of bipolar disorder, this completely revised Second Edition spans basic mechanisms, neuroimaging, viral etiology, neurofactors, current treatment implications, and modern theories of the neurobiology of bipolar disorder to stand as the most authoritative reference on this debilitating condition. Written and edited by internationally lauded experts in the field, this source covers an expansive array of topics including genetic and causal factors, neuroendocrinology, neurotransmitters and signal transduction pathways, neuroimaging and neurorecognition, and prospects for new treatment development.

The Role Of 11 Hydroxysteroid Dehydrogenase Type 1 In The Regulation Of The Hypothalamic Pituitary Adrenal Axis In Immune Mediated Arthritis Book PDF
✏Book Title : The Role of 11 hydroxysteroid Dehydrogenase Type 1 in the Regulation of the Hypothalamic pituitary adrenal Axis in Immune mediated Arthritis
✏Author : Janko Sattler
✏Publisher :
✏Release Date : 2018
✏Pages :
✏ISBN : OCLC:1188953732
✏Available Language : English, Spanish, And French

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✏The Role of 11 hydroxysteroid Dehydrogenase Type 1 in the Regulation of the Hypothalamic pituitary adrenal Axis in Immune mediated Arthritis Book Summary :

Library Of Congress Subject Headings Book PDF
✏Book Title : Library of Congress Subject Headings
✏Author : Library of Congress
✏Publisher :
✏Release Date : 1998
✏Pages :
✏ISBN : OSU:32435058286600
✏Available Language : English, Spanish, And French

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✏Library of Congress Subject Headings Book Summary :

Stress And Pain Dys Regulation In Chronic Orofacial Pain Book PDF
✏Book Title : Stress and Pain dys regulation in Chronic Orofacial Pain
✏Author : Ursula Galli
✏Publisher : Cuvillier Verlag
✏Release Date : 2008
✏Pages : 94
✏ISBN : 9783867277808
✏Available Language : English, Spanish, And French

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✏Stress and Pain dys regulation in Chronic Orofacial Pain Book Summary :