The Epigenetics of Autoimmune Diseases

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  • Author : Moncef Zouali
  • Publisher : John Wiley & Sons
  • Pages : 472 pages
  • ISBN : 9780470743560
  • Rating : /5 from reviews
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Download or Read online The Epigenetics of Autoimmune Diseases full in PDF, ePub and kindle. this book written by Moncef Zouali and published by John Wiley & Sons which was released on 01 April 2009 with total page 472 pages. We cannot guarantee that The Epigenetics of Autoimmune Diseases book is available in the library, click Get Book button and read full online book in your kindle, tablet, IPAD, PC or mobile whenever and wherever You Like. The role of epigenetic mechanisms in autoimmune disease is only now starting to become clear. Understanding these mechanisms, their effect on cellular function and the role of environmental factors is vital to determining how to manage these often debilitating and fatal diseases. Drawing on the research of leading experts, this book provides a valuable insight into this important new area of autoimmunity research and a clear, up-to-date view on the major advances in the field. Specific coverage includes: How highly developed epigenetic mechanisms are involved in several aspects of normal immune regulation, in addition to maintaining immune tolerance to self-determinants. Specific epigenetic aspects of human autoimmune diseases, including multiple sclerosis, systemic lupus erythematosus, rheumatoid arthritis, systemic sclerosis, autoimmune diabetes, thyroid autoimmunity, inflammatory bowel disease and autoimmune hepatitis. How understanding epigenetic mechanisms can lead to therapeutic strategies based on manipulation of this previously unexploited facet of immune regulation. Discussion of the novel approaches that are being investigated to prevent or treat autoimmune diseases. This book is an essential resource for those actively involved in the field. It is also of interest to basic researchers interested in understanding the origin of autoimmunity and clinical specialists interested in gaining in-depth understanding of the pathogenesis of autoimmune diseases and their treatment.

The Epigenetics of Autoimmune Diseases

The Epigenetics of Autoimmune Diseases
  • Author : Moncef Zouali
  • Publisher : John Wiley & Sons
  • Release : 01 April 2009
GET THIS BOOK The Epigenetics of Autoimmune Diseases

The role of epigenetic mechanisms in autoimmune disease is only now starting to become clear. Understanding these mechanisms, their effect on cellular function and the role of environmental factors is vital to determining how to manage these often debilitating and fatal diseases. Drawing on the research of leading experts, this book provides a valuable insight into this important new area of autoimmunity research and a clear, up-to-date view on the major advances in the field. Specific coverage includes: How highly

The Epigenetics of Autoimmunity

The Epigenetics of Autoimmunity
  • Author : Rongxin Zhang
  • Publisher : Academic Press
  • Release : 25 April 2018
GET THIS BOOK The Epigenetics of Autoimmunity

The Epigenetics of Autoimmunity covers a topic directly related to translational epigenetics. Via epigenetic mechanisms, a number of internal and external environmental risk factors, including smoking, nutrition, viral infection and the exposure to chemicals, could exert their influence on the pathogenesis of autoimmune diseases. Such factors could impact the epigenetic mechanisms, which, in turn, build relationship with the regulation of gene expression, and eventually triggering immunologic events that result in instability of immune system. Since epigenetic aberrations are known to

Epigenetics in Allergy and Autoimmunity

Epigenetics in Allergy and Autoimmunity
  • Author : Christopher Chang,Qianjin Lu
  • Publisher : Springer Nature
  • Release : 22 May 2020
GET THIS BOOK Epigenetics in Allergy and Autoimmunity

This book will address the growing roles of epigenetics in disease pathogenesis, and review the contribution of epigenetic modifications to disease onset and progression. The roles that epigenetics plays in facilitating effects of the environment on allergy and immunologic diseases will be reviewed. The book is divided into three parts – the first is an introduction to epigenetics and the methods that have been developed to study epigenetics, the second addresses epigenetics in allergic diseases and the third part will cover

The Association of Other Autoimmune Diseases in Patients With Thyroid Autoimmunity

The Association of Other Autoimmune Diseases in Patients With Thyroid Autoimmunity
  • Author : Alessandro Antonelli,Salvatore Benvenga
  • Publisher : Frontiers Media SA
  • Release : 02 November 2018
GET THIS BOOK The Association of Other Autoimmune Diseases in Patients With Thyroid Autoimmunity

Autoimmune thyroid diseases (AITD) are T cell-mediated organ-specific autoimmune disorders resulting from an immune dysregulation leading to a thyroid immune attack (Antonelli and Benvenga). Graves’ disease and Hashimoto’s thyroiditis are the two main clinical presentations of AITD, and their clinical hallmarks are thyrotoxicosis and hypothyroidism, respectively. In many cases, AITD may be associated in the same patient with other organ-specific autoimmune attacks (such as in the case of type II autoimmune polyglandular syndrome, or type I diabetes, etc). Furthermore,

Epigenetics and Dermatology

Epigenetics and Dermatology
  • Author : Qianjin Lu,Christopher C. Chang,Bruce C. Richardson
  • Publisher : Academic Press
  • Release : 16 February 2015
GET THIS BOOK Epigenetics and Dermatology

Epigenetics and Dermatology explores the role of epigenetics in the pathogenesis of autoimmune-related skin diseases and skin cancer. Leading contributors cover common and uncommon skin conditions in which extensive epigenetic research has been done. They explain how environmental exposures (chemicals, drugs, sunlight, diet, stress, smoking, infection, etc.) in all stages of life (from a fetus in-utero to an elderly person) may result in epigenetic changes that lead to development of some skin diseases in life. They also discuss the possibilities

Prognostic Epigenetics

Prognostic Epigenetics
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 01 November 2019
GET THIS BOOK Prognostic Epigenetics

This volume provides comprehensive information on how mapping an individual’s epigenome can be medically relevant and holds the potential to improve preventive medicine and precision therapeutics at an early-stage (prior to disease onset). In order to advance clinical adoption of the recently developed epigenetic approaches, it is necessary for translational scientists, clinicians, and students to gain a better understanding about epigenetic mechanisms that are associated with a particular disorder; and to be able to effectively identify biomarkers that can

Mosaic of Autoimmunity

Mosaic of Autoimmunity
  • Author : Carlo Perricone,Yehuda Shoenfeld
  • Publisher : Academic Press
  • Release : 15 February 2019
GET THIS BOOK Mosaic of Autoimmunity

The Mosaic of Autoimmunity: The Novel Factors of Autoimmune Diseases describes the multifactorial origin and diversity of expression of autoimmune diseases in humans. The term implies that different combinations of factors in autoimmunity produce varying and unique clinical pictures in a wide spectrum of autoimmune diseases. Most of the factors involved in autoimmunity can be categorized into four groups: genetic, immune defects, hormonal and environmental factors. In this book, the environmental factors are reviewed, including infectious agents, vaccines as triggers

The Role of Over Nutrition and Obesity in Multiple Sclerosis

The Role of Over Nutrition and Obesity in Multiple Sclerosis
  • Author : Ema Kantorová
  • Publisher : Unknown
  • Release : 18 May 2022
GET THIS BOOK The Role of Over Nutrition and Obesity in Multiple Sclerosis

In countries with high standard of living, lowered risk of infectious diseases is parallel to increased incidence of autoimmune diseases. One of the autoimmune disorders, multiple sclerosis, affects genetically susceptible individuals. Genetic susceptibility is supposed to interact with lifestyle and environmental factors in developing autoimmunity in MS. From this point of view, epigenetics provides the bridge between the external environment and the internal genetic system. In MS, environmental burden can modulate gene expression by epigenetic modification of chromatin components, microRNAs

Translational Autoimmunity

Translational Autoimmunity
  • Author : Nima Rezaei
  • Publisher : Academic Press
  • Release : 22 October 2021
GET THIS BOOK Translational Autoimmunity

Translational Autoimmunity: Etiology of Autoimmune Diseases is the first volume of the Translational Immunology book series. To attain its purpose as a detailed translational step to tackle autoimmunity, this volume sufficiently addresses basic questions on how the immune system is designed to distinguish self from nonself. It discusses the known mechanisms that lead to the maintenance of self-tolerance, presents potential triggers and malfunctions that impede normal immune processes, and demonstrates how the immune system induces an autoreactive state that results

The Autoimmune Diseases

The Autoimmune Diseases
  • Author : Noel R. Rose,Ian R. Mackay
  • Publisher : Academic Press
  • Release : 15 October 2019
GET THIS BOOK The Autoimmune Diseases

The Autoimmune Diseases, Sixth Edition, emphasizes the "3 P’s" of 21st Century medicine: precision, prediction and prevention. Topics cover the modern systems approach to biology that involves large amounts of personalized, ongoing physiologic data ("omics") coupled with advanced methods of analysis, new tests of genetic engineering, such as CRISPR, auto inflammatory diseases, autoimmune responses to tumor immunotherapy, and information on normal immune response and disorders. Each of the major autoimmune disorders is discussed by researchers and clinical investigators experienced in

Human Autoimmunity and Associated Diseases

Human Autoimmunity and Associated Diseases
  • Author : Kenan Demir,Selim Görgün
  • Publisher : Cambridge Scholars Publishing
  • Release : 18 May 2021
GET THIS BOOK Human Autoimmunity and Associated Diseases

The collection of essays reviews, explores, and reports state-of-the-art autoimmunity issues with a cause and effect relationship. It provides a comprehensive presentation of immunity and autoimmunity and their connection to related diseases, current trends, data and possible future developments in health sciences. As such, it represents a unique resource for medical educators, medical practitioners and academics.

Translational Studies on Inflammation

Translational Studies on Inflammation
  • Author : Ane C.F. Nunes
  • Publisher : BoD – Books on Demand
  • Release : 08 January 2020
GET THIS BOOK Translational Studies on Inflammation

Inflammation is known worldwide, from the bench to the bedside, but it is a hard theme to approach with one single point of view.In this sense, a selection of translational studies would support the medical-scientific community to better understand the complex network of the inflammatory process, its maintenance, and potential treatment targets. The eleven chapters that compose this book present interesting insights into inflammation and its mechanisms, merging classic background with innovative approaches. From the molecular basis to experimental

The Value of BCG and TNF in Autoimmunity

The Value of BCG and TNF in Autoimmunity
  • Author : Denise Faustman
  • Publisher : Academic Press
  • Release : 01 August 2018
GET THIS BOOK The Value of BCG and TNF in Autoimmunity

The Value of BCG and TNF in Autoimmune Diseases, Second Edition provides an overview on the current research related to TNF induction and the use of the BCG vaccine as a potential treatment approach to diverse forms of autoimmunity, allergies, infections and neurologic diseases. Since the initial conference (2013) and first edition of this book (2014), the field of BCG research has grown considerably. This new edition contains updates on MS and diabetes, and features at least eight additional chapters on new

Patho Epigenetics of Disease

Patho Epigenetics of Disease
  • Author : Janos Minarovits,Hans Helmut Niller
  • Publisher : Springer Science & Business Media
  • Release : 14 June 2012
GET THIS BOOK Patho Epigenetics of Disease

In multicellular organisms the establishment, maintenance, and programmed alterations of cell-type specific gene expression patterns are regulated by epigenetic mechanisms. Thus, epigenetic alterations (DNA methylation, DNA associated Polycomb-Trithorax protein complexes, histone modifications) ensure the unique transcriptional activity and phenotypic diversity of diploid cells that carry identical or nearly identical DNA sequences. Because DNA methyltransferase I (DNMT1) associates with replication foci during S phase and prefers hemimethylated DNA as a substrate, DNMT1 ensures the clonal propagation of cytosine methylation patterns (maintenance