The Detection of Biomarkers

• Author : Sibel A. Ozkan,Nurgul K. Bakirhan,Fariba Mollaraosouli
• Publisher : Academic Press
• Release : 05 December 2021

Reliable, precise and accurate detection and analysis of biomarkers remains a significant challenge for clinical researchers. Methods for the detection of biomarkers are rather complex, requiring pre-treatment steps before analysis can take place. Moreover, comparing various biomarker assays and tracing research progress in this area systematically is a challenge for researchers. The Detection of Biomarkers presents developments in biomarker detection, including methods tools and strategies, biosensor design, materials, and applications. The book presents methods, materials and procedures that are simple,

• Author : Ajit Sadana,Neeti Sadana
• Publisher : Newnes
• Release : 08 December 2014

Biomarkers and Biosensors offers thorough coverage of biomarker/biosensor interaction, current research trends, and future developments in applications of drug discovery. This book is useful to researchers in this field as well as clinicians interested in new developments in early detection and diagnosis of disease or the mode of operation of biomarkers. Biomarkers and Biosensors also emphasizes kinetics, and clearly delineates how this influences the biomarker market. Offers thorough coverage of the kinetics of biomarker interaction with the biosensor surface

• Author : Huangxian Ju,Guosong Lai,Feng Yan
• Publisher : Elsevier
• Release : 18 May 2017

Immunosensing for Detection of Protein Biomarkers not only introduces the principles, methods, and classification of immunoassay, but also presents the latest achievements in areas such as electrochemical immunosensors, nanoprobe-based immunoassay, chemiluminescence immunoassay, electrochemiluminescent immunoassay, multianalyte immunoassay, optical imaging for immunoassay, signal amplification for immunoassay, and so on. In recent years, immunosensing and immunoassay methods have attracted considerable interest due to their applications in different fields, particularly clinical diagnosis. Although a large number of academic papers in immunosensing and immunoassay have

• Author : Institute of Medicine,Committee on Developing Biomarker-Based Tools for Cancer Screening, Diagnosis, and Treatment
• Publisher : National Academies Press
• Release : 27 March 2007

Many cancer patients are diagnosed at a stage in which the cancer is too far advanced to be cured, and most cancer treatments are effective in only a minority of patients undergoing therapy. Thus, there is tremendous opportunity to improve the outcome for people with cancer by enhancing detection and treatment approaches. Biomarkers will be instrumental in making that transition. Advances in biotechnology and genomics have given scientists new hope that biomarkers can be used to improve cancer screening and

• Author : Gorachand Dutta,Arindam Biswas,Amlan Chakrabarti
• Publisher : Springer Nature
• Release : 04 January 2021

This book focusses on recent advances and different research issues in the biosensor technology and also presents theoretical, methodological, well-established and validated empirical work dealing with the technology. The book addresses challenges for the development of a point-of-care test platform. The book also describes printed chip-based assay (Lab-on-a-Chip, Lab-on-a-PCB) for rapid, inexpensive, multiplex detection of disease biomarkers in real samples. It aims to overcome existing barriers for Lab-on-a-Chip commercialization (lack of cost effective mass manufacturing methods, self-contained, fully autonomous operation

• Author : Danah A. A. A. Q. Al-Qallaf
• Publisher : Unknown
• Release : 07 June 2023

• Author : Satish Balasaheb Nimse,Min Park
• Publisher : Mdpi AG
• Release : 23 March 2022

The detection and quantification of with high precision nucleic acid biomarkers and protein biomarkers in resource-limited settings is key to the early diagnosis of diseases and for monitoring the effects of treatments. As there is an enormous demand for high-quality biomarker detection platforms that are robust and highly applicable in resource-limited settings, this book is devoted to exploring methods for detection and quantification of biomarkers, focusing on the recent advances in this field.

• Author : John Bosco Balaguru Rayappan,Jung Heon Lee
• Publisher : Springer Nature
• Release : 28 July 2021

This book highlights both conventional and nanomaterials-based biosensors for the detection of cervical cancers. It describes developments in the selective and sensitive electrochemical biosensors based on DNA for the early diagnosis of cervical cancer. Further, this book covers other nano-biosensing systems such as nano-thermometry-based sensing platforms, mechanical sensing platforms encompassing piezoelectric-based sensors, electrochemical impedance spectroscopy based on PEGylated arginine functionalized magnetic nanoparticles, and field-effect transistor-based platforms for the early detection of cervical cancer. Also, it presents conventional platforms such as

• Author : Emma O'Connor
• Publisher : Unknown
• Release : 07 June 2023

• Author : Sudhir Srivastava
• Publisher : John Wiley & Sons
• Release : 28 August 2017

Prepared by world leaders on this topic, Biomarkers in Cancer Screening and Early Detection offers a comprehensive, state-of-the-art perspective on the various research and clinical aspects of cancer biomarkers, from their discovery and development to their validation, clinical utility, and use in developing personalized cancer treatment. Offers a comprehensive, state-of-the-art perspective on the various research and clinical aspects of cancer biomarkers Provides immediately actionable information – and hopefully also inspiration – to move discovery and clinical application forward Offers vital knowledge to

• Author : Michael R. Bleavins,Claudio Carini,Mallé Jurima-Romet,Ramin Rahbari
• Publisher : John Wiley & Sons
• Release : 20 September 2011

Discover how biomarkers can boost the success rate of drug development efforts As pharmaceutical companies struggle to improve the success rate and cost-effectiveness of the drug development process, biomarkers have emerged as a valuable tool. This book synthesizes and reviews the latest efforts to identify, develop, and integrate biomarkers as a key strategy in translational medicine and the drug development process. Filled with case studies, the book demonstrates how biomarkers can improve drug development timelines, lower costs, facilitate better compound

• Author : Keith E. Herold,Avraham Rasooly
• Publisher : CRC Press
• Release : 29 May 2012

Bridging the gap between research and clinical application, Biosensors and Molecular Technologies for Cancer Diagnostics explores the use of biosensors as effective alternatives to the current standard methods in cancer diagnosis and detection. It describes the major aspects involved in detecting and diagnosing cancer as well as the basic elements of biosensors and their applications in detection and diagnostics. The book addresses cancer molecular diagnostics, including genomic and proteomic approaches, from the perspective of biosensors and biodetection. It explains how

• Author : Charles L. Edelstein
• Publisher : Academic Press
• Release : 27 October 2010

A biomarker is a molecule that is measured as a marker of normal biological processes, disease processes or the response to a diagnostic or therapeutic intervention. Kidney diseases like acute kidney injury, chronic kidney disease, diabetic nephropathy, glomerular disease, renal cancer and preeclampsia still have a high morbidity. Measurement of biomarkers in the blood or urine that detect patients at risk of kidney diseases or that detect kidney diseases in the earliest stage may ultimately result in preventative or earlier

• Author : Pallaval Veera Bramhachari,Nageswara Rao Reddy Neelapu
• Publisher : Springer Nature
• Release : 21 July 2020

This book describes various novel biomarkers for the early diagnosis of gastrointestinal (GI) cancers. It also highlights recent advances in understanding the role of molecular markers and biomarkers, such as volatile biomarkers, serum biomarkers, predictive and prognostic molecular markers for the early detection of GI cancers. Further, it discusses novel biomarkers, including circulating microRNAs, serum microRNA and plasma microRNA in GI cancer. The book presents breakthrough technologies like ultra-sensitive nano-chips, nanosensors, nanodevices, biosensors, electrochemical biosensors, optical biosensors, DNA biosensors, synthetic

• Author : Pranjal Chandra,Yen Nee Tan,Surinder P. Singh
• Publisher : Springer
• Release : 30 December 2017

This book presents recent research on cancer detection methods based on nanobiosensors, which offer ultrasensitive point-of-care diagnosis. Several methods for diagnosing cancer have been discovered and many more are currently being developed. Conventional clinical approaches to detecting cancers are based on a biopsy followed by histopathology, or on the use of biomarkers (protein levels or nucleic acid content). Biopsy is the most widely used technique; however, it is an invasive technique and is not always applicable. Furthermore, biomarker-based detection cannot