📒Targeted Killing ✍ Thomas B. Hunter

Targeted Killing Book PDF
✏Book Title : Targeted Killing
✏Author : Thomas B. Hunter
✏Publisher : Thomas Hunter
✏Release Date : 2009
✏Pages : 96
✏ISBN : 9781439252055
✏Available Language : English, Spanish, And French

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✏Targeted Killing Book Summary : This is an objective, strategic assessment of the role, usefulness, and logistical concerns posed by state-sponsored targeted killing and its overall efficiency in the current war on global terrorism.

📒Targeted Cancer Therapy ✍ Razelle Kurzrock

Targeted Cancer Therapy Book PDF
✏Book Title : Targeted Cancer Therapy
✏Author : Razelle Kurzrock
✏Publisher : Springer Science & Business Media
✏Release Date : 2008-03-07
✏Pages : 446
✏ISBN : 1603274243
✏Available Language : English, Spanish, And French

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✏Targeted Cancer Therapy Book Summary : Emerging technologies in target identification, drug discovery, molecular markers, and imaging are rapidly changing the face of cancer. This book provides a foundation of knowledge in targeted cancer therapeutics. The treatment of cancer is increasingly being individualized, based on an understanding of underlying biologic mechanisms. Poised to change the landscape in oncology, this volume provides a state-of-the-art overview. It will be valuable to practicing and academic physicians, fellows, residents and students, as well as basic scientists, interested in the cancer field.

Targeted Therapies In Oncology Book PDF
✏Book Title : Targeted Therapies in Oncology
✏Author : Giuseppe Giaccone
✏Publisher : CRC Press
✏Release Date : 2007-09-25
✏Pages : 424
✏ISBN : 1420020587
✏Available Language : English, Spanish, And French

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✏Targeted Therapies in Oncology Book Summary : Targeted therapy is one of the most burgeoning areas of development in cancer research. Increasing knowledge in tumor formation and growth at the molecular level has generated a broad array of therapeutic options, including signal transduction inhibition, anti-angiogenic and anti-vascular agents, cell cycle inhibitors, telomerase and telomere interacting agents, apoptosis inducers, and anti-invasive agents. This book presents an authoritative overview of existing molecular targeted therapies, their relevance and role for specific tumors, and their clinical efficacy and impact on patient treatment.

📒Targeted ✍ Brittany Kaiser

Targeted Book PDF
✏Book Title : Targeted
✏Author : Brittany Kaiser
✏Publisher : HarperCollins
✏Release Date : 2019-10-22
✏Pages : 400
✏ISBN : 9780062965806
✏Available Language : English, Spanish, And French

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✏Targeted Book Summary : In this explosive memoir, a political consultant and technology whistleblower reveals the disturbing truth about the multi-billion-dollar data industry, revealing to the public how companies are getting richer using our personal information and exposing how Cambridge Analytica exploited weaknesses in privacy laws to help elect Donald Trump—and how this could easily happen again in the 2020 presidential election. When Brittany Kaiser joined Cambridge Analytica—the UK-based political consulting firm funded by conservative billionaire and Donald Trump patron Robert Mercer—she was an idealistic young professional working on her fourth degree in human rights law and international relations. A veteran of Barack Obama’s 2008 campaign, Kaiser’s goal was to utilize data for humanitarian purposes, most notably to prevent genocide and human rights abuses. But her experience inside Cambridge Analytica opened her eyes to the tremendous risks that this unregulated industry poses to privacy and democracy. Targeted is Kaiser’s eyewitness chronicle of the dramatic and disturbing story of the rise and fall of Cambridge Analytica. She reveals to the public how Facebook’s lax policies and lack of sufficient national laws allowed voters to be manipulated in both Britain and the United States, where personal data was weaponized to spread fake news and racist messaging during the Brexit vote and the 2016 election. But the damage isn’t done Kaiser warns; the 2020 election can be compromised as well if we continue to do nothing. In the aftermath of the U.S. election, as she became aware of the horrifying reality of what Cambridge Analytica had done in support of Donald Trump, Kaiser made the difficult choice to expose the truth. Risking her career, relationships, and personal safety, she told authorities about the data industry’s unethical business practices, eventually testifying before Parliament about the company’s Brexit efforts and helping Special Counsel Robert Mueller’s investigation into Russian interference in the 2016 election, alongside at least 10 other international investigations. Packed with never-before-publicly-told stories and insights, Targeted goes inside the secretive meetings with Trump campaign personnel and details the promises Cambridge Analytica made to win. Throughout, Kaiser makes the case for regulation, arguing that legal oversight of the data industry is not only justifiable but essential to ensuring the long-term safety of our democracy. Targeted includes 20-30 photos.

Targeted Treatment Of The Rheumatic Diseases Book PDF
✏Book Title : Targeted Treatment of the Rheumatic Diseases
✏Author : Michael H. Weisman
✏Publisher : Elsevier Health Sciences
✏Release Date : 2010
✏Pages : 471
✏ISBN : 9781416099932
✏Available Language : English, Spanish, And French

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✏Targeted Treatment of the Rheumatic Diseases Book Summary : Michael H. Weisman, Michael Weinblatt, James S Louie, and Ronald Van Vollenhoven offer their unique insights into choosing the correct pharmacological and non-pharmacological therapies for your patients. Chapters cover the full breadth of rheumatic diseases, rheumatoid arthritis, lupus, connective tissue diseases, osteoporosis, regional pain disorders, and fibromyalgia. The full-color design presents detailed clinical photographs and treatment algorithms for visual guidance and easy reference. Covers the treatment of pediatric patients as well as adults so that you can properly address the particular needs of any patient you see. Features the guidance and specific recommendations of experts from United States and Europe for a state-of-the-art approach to the variety of treatments currently in use. Displays the clinical manifestations of rheumatic diseases in full color, along with treatment algorithms for easy at-a-glance reference.

📒Targeted Therapies ✍ Daniel Gioeli

Targeted Therapies Book PDF
✏Book Title : Targeted Therapies
✏Author : Daniel Gioeli
✏Publisher : Springer Science & Business Media
✏Release Date : 2011-06-02
✏Pages : 202
✏ISBN : 1607614782
✏Available Language : English, Spanish, And French

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✏Targeted Therapies Book Summary : This volume explores the mechanisms of resistance to targeted therapeutics. The focus is on the cancer cell signaling network, although other mechanisms of resistance including target mutation, and new areas of study such as cancer stem cells are included. Targeted Therapies: Mechanisms of Resistance highlights examples of changes in the signaling network in response to inhibition of a signaling event and underscores the importance in having a mechanistic understanding of the signaling network in cancer for developing effective targeted cancer therapies. Moreover, cutting edge tools to analyze the cell signaling network will be discussed. This includes the leading edge of techniques as well as computational biology and systems theory. This volume provides the reader with both an overview as well as a detailed perspective on the mechanisms of resistance to targeted therapeutics and will be of great value to the oncologist, the physician-scientist treating patients and the translational scientist working on any aspect of targeted therapeutics.

Targeted Interference With Signal Transduction Events Book PDF
✏Book Title : Targeted Interference with Signal Transduction Events
✏Author : B. Groner
✏Publisher : Springer Science & Business Media
✏Release Date : 2007-08-09
✏Pages : 188
✏ISBN : 9783540312093
✏Available Language : English, Spanish, And French

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✏Targeted Interference with Signal Transduction Events Book Summary : This book does nothing less than lay out the state of development of tomorrow’s cancer drugs, directed against growth factors, growth factor receptors and intracellular signaling molecules with kinase activities. The sequencing of the human genome and insights into signaling pathways have contributed to the understanding of cancer etiology and the development of new, improved cancer drugs such as Herceptin and Glivec. The deregulation of pathways due to mutated cancer genes provides the conceptual basis for future progress. Will it be possible to derive more efficient cancer drugs?

Prodrugs And Targeted Delivery Book PDF
✏Book Title : Prodrugs and Targeted Delivery
✏Author : Jarkko Rautio
✏Publisher : John Wiley & Sons
✏Release Date : 2011-01-11
✏Pages : 520
✏ISBN : 9783527633180
✏Available Language : English, Spanish, And French

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✏Prodrugs and Targeted Delivery Book Summary : This topical reference and handbook addresses the chemistry, pharmacology, toxicology and the patentability of prodrugs, perfectly mirroring the integrated approach prevalent in today's drug design. It summarizes current experiences and strategies for the rational design of prodrugs, beginning at the early stages of the development process, as well as discussing organ- and site-selective prodrugs. Every company employing medicinal chemists will be interested in this practice-oriented overview of a key strategy in modern drug discovery and development.

Molecularly Targeted Therapy For Childhood Cancer Book PDF
✏Book Title : Molecularly Targeted Therapy for Childhood Cancer
✏Author : Peter J. Houghton
✏Publisher : Springer Science & Business Media
✏Release Date : 2010-09-10
✏Pages : 536
✏ISBN : 038769062X
✏Available Language : English, Spanish, And French

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✏Molecularly Targeted Therapy for Childhood Cancer Book Summary : Each chapter will focus on the known molecular characteristics of specific childhood cancers, focusing on how the molecular ‘drivers’ can be exploited from a therapeutic standpoint with currently available targeted agents. Where applicable, integration of targeted therapies with conventional cytotoxic agents will be considered. This volume will provide a comprehensive summary of molecular characteristics of childhood cancers, and how the changes involved in transformation provide us with opportunities for developing relatively less toxic, but curative, therapies.

Nonlinear Targeted Energy Transfer In Mechanical And Structural Systems Book PDF
✏Book Title : Nonlinear Targeted Energy Transfer in Mechanical and Structural Systems
✏Author : Alexander F. Vakakis
✏Publisher : Springer Science & Business Media
✏Release Date : 2008-12-24
✏Pages : 1030
✏ISBN : 9781402091308
✏Available Language : English, Spanish, And French

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✏Nonlinear Targeted Energy Transfer in Mechanical and Structural Systems Book Summary : This monograph evolved over a period of nine years from a series of papers and presentations addressing the subject of passive vibration control of mechanical s- tems subjected to broadband, transient inputs. The unifying theme is Targeted - ergy Transfer – TET, which represents a new and unique approach to the passive control problem, in which a strongly nonlinear, fully passive, local attachment, the Nonlinear Energy Sink – NES, is employed to drastically alter the dynamics of the primary system to which it is attached. The intrinsic capacity of the properly - signed NES to promote rapid localization of externally applied (narrowband) - bration or (broadband) shock energy to itself, where it can be captured and dis- pated, provides a powerful strategy for vibration control and the opens the pos- bility for a wide range of applications of TET, such as, vibration and shock i- lation, passive energy harvesting, aeroelastic instability (?utter) suppression, se- mic mitigation, vortex shedding control, enhanced reliability designs (for ex- ple in power grids) and others. The monograph is intended to provide a thorough explanation of the analytical, computational and experimental methods needed to formulate and study TET in mechanical and structural systems. Several prac- cal engineering applications are examined in detail, and experimental veri?cation and validation of the theoretical predictions are provided as well. The authors also suggest a number of possible future applications where application of TET seems promising. The authors are indebted to a number of sponsoring agencies.