Systems Biology in Toxicology and Environmental Health

• Author : Rebecca Fry
• Publisher : Academic Press
• Release : 11 June 2015

Systems Biology in Toxicology and Environmental Health uses a systems biological perspective to detail the most recent findings that link environmental exposures to human disease, providing an overview of molecular pathways that are essential for cellular survival after exposure to environmental toxicants, recent findings on gene-environment interactions influencing environmental agent-induced diseases, and the development of computational methods to predict susceptibility to environmental agents. Introductory chapters on molecular and cellular biology, toxicology and computational biology are included as well as an

• Author : Steve Gilbert,Asish Mohapatra,Sol Bobst,Antoinette Hayes,Sara T. Humes
• Publisher : Academic Press
• Release : 16 May 2020

This new fifth edition of Information Resources in Toxicology offers a consolidated entry portal for the study, research, and practice of toxicology. Both volumes represents a unique, wide-ranging, curated, international, annotated bibliography, and directory of major resources in toxicology and allied fields such as environmental and occupational health, chemical safety, and risk assessment. The editors and authors are among the leaders of the profession sharing their cumulative wisdom in toxicology’s subdisciplines. This edition keeps pace with the digital world

• Author : Anonim
• Publisher : Unknown
• Release : 30 June 1993

• Author : Mercurio
• Publisher : Jones & Bartlett Publishers
• Release : 30 August 2016

While the historic view is that toxicology is the study of poisons, in fact it is just as appropriate to consider modern toxicology as a way of determining new chemotherapies for cancer, microbial diseases, parasites or fungal infections.Biological Toxicology will thoroughly prepare your students for participation in toxicology research. Through a presentation of experimental evidence, students will understand the process for designing and collecting data in biological toxicology research.In five sections, the book examines the foundations of the

• Author : Ernest Hodgson
• Publisher : Academic Press
• Release : 30 June 2022

Environmental toxicology is generally held to be the study of the potential of constituents of outdoor environments to impact either human health or the biological structure of the ecosystems involved. This volume is a first attempt to integrate toxicological studies of all of the many human environments, both indoor and outdoor, and their complex interrelationships. Included are considerations of natural environments, the agroecosystem, occupational, urban and domestic environments as well as the environment associated with Superfund sites and military deployments.

• Author : P.J. Bert Hakkinen,Asish Mohapatra,Steven G. G. Gilbert
• Publisher : Academic Press
• Release : 19 August 2009

This latest version of Information Resources in Toxicology (IRT) continues a tradition established in 1982 with the publication of the first edition in presenting an extensive itemization, review, and commentary on the information infrastructure of the field. This book is a unique wide-ranging, international, annotated bibliography and compendium of major resources in toxicology and allied fields such as environmental and occupational health, chemical safety, and risk assessment. Thoroughly updated, the current edition analyzes technological changes and is rife with online tools

• Author : Anonim
• Publisher : Academic Press
• Release : 30 July 2021

Proteomics and Systems Biology, Volume 127 in the Advances in Protein Chemistry and Structural Biology series, outlines current proteomic methodologies and discuss the challenges in future applications of systems biology in a number of biomedical/bioscience subjects. In last few decades, advances in genomics, proteomics, metabolomics, glycomics, venomics, etc., have produced vast large-scale datasets that need to be analyzed with a single main objective of understanding biological systems as a whole. Such understanding will allow us to predict and characterize the

• Author : Mark G. Robson,William A. Toscano
• Publisher : John Wiley & Sons
• Release : 22 March 2007

Written by experts in the field, this important book provides an introduction to current risk assessment practices and procedures and explores the intrinsic complexities, challenges, and controversies associated with analysis of environmental health risks. Environmental Health Risk Assessment for Public Health offers 27 substantial chapters on risk-related topics that include: What Is Risk and Why Study Risk Assessment The Risk Assessment–Risk Management Paradigm Risk Assessment and Regulatory Decision-Making in Environmental Health Toxicological Basis of Risk Assessment The Application of PBPK

• Author : Ali S. Faqi
• Publisher : Academic Press
• Release : 03 November 2016

A Comprehensive Guide to Toxicology in Nonclinical Drug Development, Second Edition, is a valuable reference designed to provide a complete understanding of all aspects of nonclinical toxicology in the development of small molecules and biologics. This updated edition has been reorganized and expanded to include important topics such as stem cells in nonclinical toxicology, inhalation and dermal toxicology, pitfalls in drug development, biomarkers in toxicology, and more. Thoroughly updated to reflect the latest scientific advances and with increased coverage of

• Author : Anonim
• Publisher : ScholarlyEditions
• Release : 26 December 2012

Chlorinated Hydrocarbons—Advances in Research and Application: 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Chlorinated Hydrocarbons. The editors have built Chlorinated Hydrocarbons—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Chlorinated Hydrocarbons in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Chlorinated Hydrocarbons—Advances in Research and

• Author : National Academies of Sciences, Engineering, and Medicine,Division on Earth and Life Studies,Board on Environmental Studies and Toxicology,Committee on the Review of Environmental Protection Agency's Science to Achieve Results Research Grants Program
• Publisher : National Academies Press
• Release : 24 July 2017

Environmental research has driven landmark improvements that led to the protection of human and ecosystem health. Recognizing the value of knowledge generated by environmental research and the ingenuity within academic and nonprofit institutions, the US Environmental Protection Agency (EPA) created a program known as Science to Achieve Results, or STAR, in 1995. STAR is EPA's primary competitive extramural grants program. A Review of the Environmental Protection Agency's Science to Achieve Results Research Program assesses the program's scientific merit, public benefits, and

• Author : Natàlia Garcia-Reyero,Cheryl A. Murphy
• Publisher : Springer
• Release : 24 February 2018

Social pressure to minimize the use of animal testing, the ever-increasing concern on animal welfare, and the need for more human-relevant and more predictive toxicity tests are some of the drivers for new approaches to chemical screening. This book focuses on The Adverse Outcome Pathway, an analytical construct that describes a sequential chain of causally linked events at different levels of biological organization that lead to an adverse health or ecotoxicological effect. While past efforts have focused on toxicological pathway-based

• Author : Ali S. Faqi
• Publisher : Academic Press
• Release : 18 October 2012

A Comprehensive Guide to Toxicology in Preclinical Drug Development is a resource for toxicologists in industry and regulatory settings, as well as directors working in contract resource organizations, who need a thorough understanding of the drug development process. Incorporating real-life case studies and examples, the book is a practical guide that outlines day-to-day activities and experiences in preclinical toxicology. This multi-contributed reference provides a detailed picture of the complex and highly interrelated activities of preclinical toxicology in both small molecules

• Author : Ming-Ho Yu,Humio Tsunoda,Masashi Tsunoda
• Publisher : CRC Press
• Release : 16 November 2011

Human survival depends on the availability of clean air, water, and food and on the welfare of plants and animals. However, anthropogenic and naturally occurring chemicals can cause adverse effects on living organisms and ecological processes. Environmental Toxicology: Biological and Health Effects of Pollutants, Third Edition presents fundamental information on the effects of environmental toxicants on living systems. It focuses on the chemical and biological characteristics of major pollutants found in the air, water, and soil and relates them to

• Author : Gary W. Miller
• Publisher : Academic Press
• Release : 15 June 2020

The Exposome: A New Paradigm for the Environment and Health, Second Edition, is a thoroughly expanded and updated edition of The Exposome: A Primer, the first book dedicated to the topic. This new release outlines the purpose and scope of this emerging field of study, its practical applications, and how it complements a broad range of disciplines. The book contains sections on -omics-based technologies, newer detection methods, managing and integrating exposome data (including maps, models, computation and systems biology), and