The immunology of cellular stress proteins

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  • Author : Willem Van Eden
  • Publisher : Frontiers E-books
  • Pages : null pages
  • ISBN : 288919325X
  • Rating : /5 from reviews
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Download or Read online The immunology of cellular stress proteins full in PDF, ePub and kindle. this book written by Willem Van Eden and published by Frontiers E-books which was released on 05 October 2014 with total page null pages. We cannot guarantee that The immunology of cellular stress proteins book is available in the library, click Get Book button and read full online book in your kindle, tablet, IPAD, PC or mobile whenever and wherever You Like. Stress proteins or heat-shock proteins (HSP) are evolutionary conserved proteins present in every prokaryotic and eukaryotic cell. Their main function is to protect cells and proteins from damage under stressful circumstances. The latter circumstances do include the cell and protein damaging effects of inflammation. The discovery of mycobacterial HSP60 being a critical antigen in the model of adjuvant arthritis, has led to studies that showed the immuno-dominance of microbial HSP60 and the potential of the microbial HSP induced repertoire of antibodies and T cells to cross-recognize the self-HSP homologues of stressed cells. Since then, the research in the immunology of stress proteins started to comprise a widening spectrum of topics with potential medical relevance. Interestingly, since stress proteins have their activities in both innate and adaptive immunity, they are key elements in the cross-roads between both arms of the immune system. Stress proteins or HSP can be considered as functional 'biomarkers' of inflammation. They are up-regulated locally during inflammation and interestingly, they seem to function as targets for anti-inflammatory regulatory T cells. In experimental models of autoimmunity, mainly arthritis, administration of HSP peptides have been shown to suppress disease. First clinical trials have shown the anti-inflammatory nature of T cell responses to Hsp. In type I diabetes and in rheumatoid arthritis, parenteral and oral administration of Hsp peptides were shown to induce a bias in pro-inflammatory T cells, switching them in the direction of regulatory cytokine production (IL4, IL5 and IL10). In addition a raised level of a marker of natural T regulatory cells, the transcription factor FoxP3, was noted in the RA trial. Other inflammatory diseases or diseases with inflammatory components which feature the immune imprint of the up-regulated Hsp are atherosclerosis, inflammatory bowel diseases, multiple sclerosis and atopic diseases such atopic dermatitis and allergic asthma.

The immunology of cellular stress proteins

The immunology of cellular stress proteins
  • Author : Willem Van Eden,Ruurd Van Der Zee,Cristina Bonorino
  • Publisher : Frontiers E-books
  • Release : 05 October 2014
GET THIS BOOK The immunology of cellular stress proteins

Stress proteins or heat-shock proteins (HSP) are evolutionary conserved proteins present in every prokaryotic and eukaryotic cell. Their main function is to protect cells and proteins from damage under stressful circumstances. The latter circumstances do include the cell and protein damaging effects of inflammation. The discovery of mycobacterial HSP60 being a critical antigen in the model of adjuvant arthritis, has led to studies that showed the immuno-dominance of microbial HSP60 and the potential of the microbial HSP induced repertoire of

Stress Consequences

Stress Consequences
  • Author : George Fink
  • Publisher : Academic Press
  • Release : 06 April 2010
GET THIS BOOK Stress Consequences

Stress is a universal phenomenon that impacts adversely on most people. This volume provides a readily accessible compendium that focuses on the physical and psychological consequences of stress for individuals and society. Clinical attention focuses on disorders of the stress control system (e.g. Cushing’s Syndrome: Addison’s Disease) and the adverse impact of stress on human physical and mental health. Detailed reviews address disorders such as PTSD, anxiety, major depression, psychoses and related disorders such as combat fatigue

Stress Science

Stress Science
  • Author : George Fink
  • Publisher : Unknown
  • Release : 18 October 2021
GET THIS BOOK Stress Science

Stress is a universal phenomenon that impacts adversely on most people. This volume provides a readily accessible compendium that explains the phenomenon of stress, the neural, endocrine and molecular mechanisms involved, the clinical effects, and the impact on individuals and society. Clinical attention focuses on disorders of the stress control system (e.g. Cushing's Syndrome: Addison's Disease) and the adverse impact of stress on human physical and mental health . Detailed reviews address disorders such as PTSD, anxiety, major depression, psychoses

Heat Shock Proteins Potent Mediators of Inflammation and Immunity

Heat Shock Proteins  Potent Mediators of Inflammation and Immunity
  • Author : Alexzander A.A. Asea,Antonio De Maio
  • Publisher : Springer Science & Business Media
  • Release : 05 September 2007
GET THIS BOOK Heat Shock Proteins Potent Mediators of Inflammation and Immunity

This book provides the most up-to-date review on new mechanisms and provides exciting insights into how heat shock proteins modulate the hosts’ immune response. Written by leaders in the field of heat shock protein immunobiology, the chapters systematically and in a step-wise fashion take the reader through the fascinating sequence of events by which heat shock proteins activate immune responses and provide answers as to its biological significance to the host.

Stress Depression Inflammation and Personalized Medicine

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  • Author : Pharm Tao
  • Publisher : Lulu Press, Inc
  • Release : 31 August 2016
GET THIS BOOK Stress Depression Inflammation and Personalized Medicine

Psychological stress has been associated with higher levels of inflammation and the risks of many physical disorders including heart diseases. Inflammatory processes are the common complications of a wide range of diseases including diabetes and cancer. Inflammation can be enhanced by stress and depression, such as in the condition of troubled relationships. The emerging field of psychoneuroimmunology (PNI) focuses on the interactions among the immune system, the central nervous system (CNS), and behavior. Both genetic and environmental factors can influence

Immunity and Inflammation in Health and Disease

Immunity and Inflammation in Health and Disease
  • Author : Shampa Chatterjee,Wolfgang Jungraithmayr,Debasis Bagchi
  • Publisher : Academic Press
  • Release : 31 August 2017
GET THIS BOOK Immunity and Inflammation in Health and Disease

Immunity and Inflammation in Health and Disease: Emerging Roles of Nutraceuticals and Functional Foods in Immune Support provides a comprehensive description of the various pathways by which the vertebrate immune system works, the signals that trigger immune response and how fnew and novel nutraceuticals and functional foods, can be used to contain inflammation and also to boost immunity and immune health. Inflammation is a tool to fight pathogens and the vertebrate immune system has a very complex network of cells

Cytokines Stress and Depression

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  • Author : Robert Dantzer,Emmanuelle E. Wollmann,Raz Yirmiya
  • Publisher : Springer
  • Release : 23 March 2013
GET THIS BOOK Cytokines Stress and Depression

Cytokines had been characterized in the early eighties as communication mole cules between immune cells, and between immunocytes and other peripheral cells, such as fibroblasts and endothelial cells. They play a key role in the regulation of the immune response and the coordination of the host response to infection. Based on these biological properties, nobody would have predicted that one decade later cytokines would burst upon neurosciences and permeate into several avenues of current research. In neurology, the connection between

Stress and Immunity

Stress and Immunity
  • Author : Inna B. Mertsalova
  • Publisher : FriesenPress
  • Release : 02 May 2017
GET THIS BOOK Stress and Immunity

More Than a Book About Stress – A Self-Help Tool That Gathers All You Need to Know to Stay Healthy In recent years, we have gained increasing knowledge of the roles stress and stress hormones play in our health. It is amazing how the presentation of a stressor—whether in one event or a series of events—might involve us in appraising the environmental challenge and lead us to the “fight-or-flight” response on a physiological level. The idea that stress has

Stress Stress Hormones and the Immune System

Stress  Stress Hormones and the Immune System
  • Author : Julia C. Buckingham,Glenda E. Gillies,Anne-Marie Cowell
  • Publisher : Wiley-Blackwell
  • Release : 29 December 1997
GET THIS BOOK Stress Stress Hormones and the Immune System

In recent years hard scientific evidence has emerged which links stress and various disease states. The mechanisms underlying the interplay between brain-neuroendocrine and immune systems are the focus of much current research. Unlike other recent publications which are for specialists and frequently compromise detailed accounts, this book is for researchers who require a general insight into the topic.

The Psychoneuroimmunology of Chronic Disease

The Psychoneuroimmunology of Chronic Disease
  • Author : Kathleen Kendall-Tackett,Kathleen A. Kendall-Tackett
  • Publisher : Amer Psychological Assn
  • Release : 18 October 2021
GET THIS BOOK The Psychoneuroimmunology of Chronic Disease

Recent years have witnessed considerable growth in the field of psychoneuroimmunology (PNI), which describes how psychological factors, such as stress and depression, impact the neurological and immune systems. Research increasingly indicates that psychological states play a key role in the development and exacerbation of inflammatory diseases such as heart disease, diabetes, multiple sclerosis, Alzheimers, and autoimmune disorders. In this book, editor Kathleen Kendall-Tackett and an elite group of researchers explore the ways physical and psychological stressors such as poor sleep,

Cytokines

Cytokines
  • Author : Robert E. Faith,Anthony J. Murgo,Robert A. Good,Nicholas P. Plotnikoff
  • Publisher : CRC Press
  • Release : 10 October 2006
GET THIS BOOK Cytokines

Cytokine involvement in the immune system's response to stress is now very well documented. Cytokine activity has been implicated in a variety of mental and physical diseases, and has been shown to have a significant role in fueling the vicious circle of depression and illness. The first edition of Cytokines: Stress and Immunity pointed out

Stress and Immune Based Diseases an Issue of Immunology and Allergy Clinics

Stress and Immune Based Diseases  an Issue of Immunology and Allergy Clinics
  • Author : Gailen D. Marshall
  • Publisher : W B Saunders Company
  • Release : 01 December 2010
GET THIS BOOK Stress and Immune Based Diseases an Issue of Immunology and Allergy Clinics

This edition of Immunology and Allergy Clinics focuses on Stress and Immune-Based Diseases. Articles include: The Adverse Effects of Psychological Stress on Immunoregulatory Balance: Application to Human Inflammatory Diseases; Impact of Psychological Stress on Chronic Fatigue Syndrome Patients;Stress and Asthma ;Stress and Allergic Diseases; Stress and Autoimmune Diseases;Psychosocial influences of Stress in Cancer Patients;Stress and Wound Healing and Neuroendocrine Effects of Stress on Immunity in the Elderly:mpact on Risk for Inflammatory Diseases.

Autophagy Cancer Other Pathologies Inflammation Immunity Infection and Aging

Autophagy  Cancer  Other Pathologies  Inflammation  Immunity  Infection  and Aging
  • Author : M. A. Hayat
  • Publisher : Academic Press
  • Release : 29 July 2013
GET THIS BOOK Autophagy Cancer Other Pathologies Inflammation Immunity Infection and Aging

Understanding the importance and necessity of the role of autophagy in health and disease is vital for the studies of cancer, aging, neurodegeneration, immunology, and infectious diseases. Comprehensive and forward thinking, these books offer a valuable guide to both cellular processes while inciting researchers to explore their potentially important connections. Considering that autophagy is associated with numerous biological processes, including cellular development and differentiation, cancer (both antitumor and protumor functions), immunity, infectious diseases, inflammation, maintenance of homeostasis, response to cellular

Mind over Matter Regulation of Peripheral Inflammation by the CNS

Mind over Matter   Regulation of Peripheral Inflammation by the CNS
  • Author : Michael Schäfer,Christoph Stein
  • Publisher : Springer
  • Release : 06 December 2012
GET THIS BOOK Mind over Matter Regulation of Peripheral Inflammation by the CNS

Several new developments in the field of neuroimmunology with focus on the brain-to-immune system communication have been the incentive for this PIR volume. It covers topics such as brain-immune interactions, the impact of stress on the immune response, pain and immunosuppression, the modulation of inflammation and pain by the sympathetic nervous system, consequences of nerve injury for the immune system, neuronal mechanisms of immune cell recruitment, and the modulation of the immune response by corticotropin-releasing hormone or adenosine. The authors

Psychoneuroimmunology

Psychoneuroimmunology
  • Author : Qing Yan
  • Publisher : Springer
  • Release : 03 October 2016
GET THIS BOOK Psychoneuroimmunology

This book provides a comprehensive overview of the cutting-edge discoveries and the systems approaches related to the multi-disciplinary field of psychoneuroimmunology (PNI), which may provide the scientific basis for mind-body relationships, and aid in the development of personalized medicine. Specifically, the book focuses on the systems biology studies of complex mechanisms, such as stress and inflammation. There is strong evidence supporting the close relationship between stress, inflammation, and disorders including obesity, cardiovascular disease, diabetes, skin diseases, and sleep disorders. As