Stem Cell Bioprocessing

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  • Author : Tiago G Fernandes
  • Publisher : Elsevier
  • Pages : 236 pages
  • ISBN : 1908818301
  • Rating : /5 from reviews
CLICK HERE TO GET THIS BOOK >>>Stem Cell Bioprocessing

Download or Read online Stem Cell Bioprocessing full in PDF, ePub and kindle. this book written by Tiago G Fernandes and published by Elsevier which was released on 15 November 2013 with total page 236 pages. We cannot guarantee that Stem Cell Bioprocessing book is available in the library, click Get Book button and read full online book in your kindle, tablet, IPAD, PC or mobile whenever and wherever You Like. Stem cell bioprocessing describes the main large-scale bioprocessing strategies for both stem cell culture and purification, envisaging the application of these cells for regenerative medicine and drug screening. Bioreactor configurations are described, including their applications for stem cell expansion, and stem cell separation techniques such as isolation and purification are discussed. Basic definitions are provided concerning the different types of stem cells, from adult stem cells to the more recent induced pluripotent stem cells. The main characteristics of these different stem cell types are described, alongside the molecular mechanisms underlying their self-renewal and differentiation. The book also focuses on methodologies currently used for in vitro stem cell culture under static conditions, including the challenge of xeno-free culture conditions, as well as culture parameters that influence stem cell culture. Approaches for both stem cell culture and separation in micro-scale conditions are presented, including the use of cellular microarrays for high-throughput screening of the effect of both soluble and extracellular matrix molecules. A further section is dedicated to application of stem cells for regenerative medicine. Maintains a unique focus on both the basic stem cell biology concepts, and their translation to large-scale bioprocessing approaches Envisages the use of stem cells in regenerative medicine and drug screening applications Discusses the application of microscale techniques as a tool to perform basic stem cell biology studies

Stem Cell Bioprocessing

Stem Cell Bioprocessing
  • Author : Tiago G Fernandes,Maria Margarida Diogo,Joaquim M. S. Cabral
  • Publisher : Elsevier
  • Release : 15 November 2013
GET THIS BOOK Stem Cell Bioprocessing

Stem cell bioprocessing describes the main large-scale bioprocessing strategies for both stem cell culture and purification, envisaging the application of these cells for regenerative medicine and drug screening. Bioreactor configurations are described, including their applications for stem cell expansion, and stem cell separation techniques such as isolation and purification are discussed. Basic definitions are provided concerning the different types of stem cells, from adult stem cells to the more recent induced pluripotent stem cells. The main characteristics of these different

Bioprocessing for Cell Based Therapies

Bioprocessing for Cell Based Therapies
  • Author : Che J. Connon
  • Publisher : John Wiley & Sons
  • Release : 06 February 2017
GET THIS BOOK Bioprocessing for Cell Based Therapies

With contributions from leading, international academics and industrial practitioners, Bioprocessing for Cell-Based Therapies explores the very latest techniques and guidelines in bioprocess production to meet safety, regulatory and ethical requirements, for the production of therapeutic cells, including stem cells. An authoritative, cutting-edge handbook on bioprocessing for the production of therapeutic cells with extensive illustrations in full colour throughout An authoritative, cutting-edge handbook on bioprocessing for the production of therapeutic cells with extensive illustrations in full colour throughout In depth discussion

Stem Cell Bioprocessing and Manufacturing

Stem Cell Bioprocessing and Manufacturing
  • Author : Joaquim M. S. Cabral,Cláudia Lobato da Silva,Maria Margarida Diogo
  • Publisher : MDPI
  • Release : 20 January 2021
GET THIS BOOK Stem Cell Bioprocessing and Manufacturing

The next healthcare revolution will apply regenerative medicines using human cells and tissues. The aim of the regenerative medicine approach is to create biological therapies or substitutes in vitro for the replacement or restoration of tissue function in vivo lost through failure or disease. However, whilst science has revealed the potential, and early products have shown the power of such therapies, there is an immediate and long-term need for expertise with the necessary skills to face the engineering and life

Bioreactors for Stem Cell Expansion and Differentiation

Bioreactors for Stem Cell Expansion and Differentiation
  • Author : Joaquim M.S. Cabral,Claudia Lobato da Silva
  • Publisher : CRC Press
  • Release : 03 September 2018
GET THIS BOOK Bioreactors for Stem Cell Expansion and Differentiation

An international team of investigators presents thought-provoking reviews of bioreactors for stem cell expansion and differentiation and provides cutting-edge information on different bioreactor systems. The authors offer novel insights into bioreactor-based culture systems specific for tissue engineering, including sophisticated and cost-effective manufacturing strategies geared to overcome technological shortcomings that currently preclude advances towards product commercialization. This book in the fields of stem cell expansion, bioreactors, bioprocessing, and bio and tissue engineering, gives the reader a full understanding of the state-of-art

Stem Cell Manufacturing

Stem Cell Manufacturing
  • Author : Joaquim M. S. Cabral,Claudia Lobato da Silva,Lucas G. Chase,Maria Margarida Diogo
  • Publisher : Elsevier
  • Release : 24 July 2016
GET THIS BOOK Stem Cell Manufacturing

Stem Cell Manufacturing discusses the required technologies that enable the transfer of the current laboratory-based practice of stem cell tissue culture to the clinic environment as therapeutics, while concurrently achieving control, reproducibility, automation, validation, and safety of the process and the product. The advent of stem cell research unveiled the therapeutic potential of stem cells and their derivatives and increased the awareness of the public and scientific community for the topic. The successful manufacturing of stem cells and their derivatives

Stem Cell Bioprocessing and Manufacturing

Stem Cell Bioprocessing and Manufacturing
  • Author : Joaquim M. S. Cabral,Cláudia Lobato da Silva,Maria Margarida Diogo
  • Publisher : Unknown
  • Release : 25 September 2022
GET THIS BOOK Stem Cell Bioprocessing and Manufacturing

The next healthcare revolution will apply regenerative medicines using human cells and tissues. The aim of the regenerative medicine approach is to create biological therapies or substitutes in vitro for the replacement or restoration of tissue function in vivo lost through failure or disease. However, whilst science has revealed the potential, and early products have shown the power of such therapies, there is an immediate and long-term need for expertise with the necessary skills to face the engineering and life

Stem Cells and Revascularization Therapies

Stem Cells and Revascularization Therapies
  • Author : Hyunjoon Kong,Andrew J. Putnam,Lawrence B. Schook
  • Publisher : CRC Press
  • Release : 13 December 2011
GET THIS BOOK Stem Cells and Revascularization Therapies

In the last few decades, significant advancements in the biology and engineering of stem cells have enabled progress in their clinical application to revascularization therapies. Some strategies involve the mobilization of endogenous stem cell populations, and others employ cell transplantation. However, both techniques have benefited from multidis

Stem Cell Engineering

Stem Cell Engineering
  • Author : Robert M. Nerem,Jeanne Loring,Todd C. McDevitt,Sean P. Palecek,David V. Schaffer,Peter W. Zandstra
  • Publisher : Springer
  • Release : 12 June 2014
GET THIS BOOK Stem Cell Engineering

This book describes a global assessment of stem cell engineering research, achieved through site visits by a panel of experts to leading institutes, followed by dedicated workshops. The assessment made clear that engineers and the engineering approach with its quantitative, system-based thinking can contribute much to the progress of stem cell research and development. The increased need for complex computational models and new, innovative technologies, such as high-throughput screening techniques, organ-on-a-chip models and in vitro tumor models require an increasing

Centrifugal recovery of embryonic stem cells for regenerative medicine bioprocessing

Centrifugal recovery of embryonic stem cells for regenerative medicine bioprocessing
  • Author : Ju Wei Wong
  • Publisher : Unknown
  • Release : 25 September 2022
GET THIS BOOK Centrifugal recovery of embryonic stem cells for regenerative medicine bioprocessing

In order to realise the potential of embryonic stem (ES) cells as a regenerative medicine, it is crucial that economical, robust and scalable bioprocesses be established. Because bioprocesses irrevocably define the safety and efficacy of any biologically derived product, an understanding of the the impact of the engineering environment on ES cells is sought. This thesis uses murine ES cells as a mimic for ES cell types that will be used in cell based regenerative medicine applications to examine the

Development of a Scalable Bioprocess for the Culture of Undifferentiated Murine Embryonic Stem Cells microform

Development of a Scalable Bioprocess for the Culture of Undifferentiated Murine Embryonic Stem Cells  microform
  • Author : Elaine Y. L. (Elaine Yan Ling) Fok
  • Publisher : Library and Archives Canada = Bibliothèque et Archives Canada
  • Release : 25 September 2022
GET THIS BOOK Development of a Scalable Bioprocess for the Culture of Undifferentiated Murine Embryonic Stem Cells microform

A reliable source of qualified ES cells would enable the development of protocols to test their potential in regenerative medicine models and the design of robust assays to study stem cell differentiation and signaling. Unfortunately, conventional ES cell culture methods are impractical for large-scale cell production under controlled conditions. Two stirred-suspension undifferentiated ES cell culture systems were developed and compared with tissue culture flask and Petri dish controls. Fifteen-day ES cell microcarrier cultures expanded 192 +/- 11.3-fold, with a doubling time