Site Specific and Global Epigenomic Editing

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  • Author : Feng C Zhou
  • Publisher : Academic Press
  • Pages : 704 pages
  • ISBN : 9780128193983
  • Rating : /5 from reviews
CLICK HERE TO GET THIS BOOK >>>Site Specific and Global Epigenomic Editing

Download or Read online Site Specific and Global Epigenomic Editing full in PDF, ePub and kindle. this book written by Feng C Zhou and published by Academic Press which was released on 15 June 2022 with total page 704 pages. We cannot guarantee that Site Specific and Global Epigenomic Editing book is available in the library, click Get Book button and read full online book in your kindle, tablet, IPAD, PC or mobile whenever and wherever You Like. In recent years, alongside the largely popularized advances in human genome editing and CRISPR-cas9-driven therapeutics, epigenomic editing has made strong strides, though a clear understanding is still forming in the field of the exact role that epigenetics play in pathogenesis, the full range of sites for possible epigenetic modification, and the potential to target these sites to modulate disease progression. Key questions for researchers embarking in this field include: Which of the hundreds of epigenomic marks and features are relevant, and which of those are likely to serve a role in regulating gene expression, cell behavior, and phenotypic outcomes? This volume is the first to provide a thorough, conceptual introduction to the field of epigenetic regulation and a thorough accounting of sites for possible epigenetic edits and disease modulation. Protocols, and applied case studies examine early disease targets and likely pathways of therapeutic significance, while also outlining common challenges in the field, and the addressing the range of bioethical questions that come with altering phenotypes. This book addresses its topic in a comprehensive, but accessible manner, highlighting practical tools and burning questions remaining in the field to enable fresh research. Offers a full, conceptual and applied framework for implementing epigenomic editing in biological research and drug discovery Discusses fundamental theory, experimental design, and applied approaches alongside common research challenges and bioethical concerns Examines epigenomic editing's potential role in modulation of developmental, neuropsychiatric, and immunological disorders, as well as viral infections and cancer

Site Specific and Global Epigenomic Editing

Site Specific and Global Epigenomic Editing
  • Author : Feng C Zhou
  • Publisher : Academic Press
  • Release : 15 June 2022
GET THIS BOOK Site Specific and Global Epigenomic Editing

In recent years, alongside the largely popularized advances in human genome editing and CRISPR-cas9-driven therapeutics, epigenomic editing has made strong strides, though a clear understanding is still forming in the field of the exact role that epigenetics play in pathogenesis, the full range of sites for possible epigenetic modification, and the potential to target these sites to modulate disease progression. Key questions for researchers embarking in this field include: Which of the hundreds of epigenomic marks and features are

Quantitative Genetics Genomics and Plant Breeding 2nd Edition

Quantitative Genetics  Genomics and Plant Breeding  2nd Edition
  • Author : Manjit S. Kang
  • Publisher : CABI
  • Release : 01 April 2020
GET THIS BOOK Quantitative Genetics Genomics and Plant Breeding 2nd Edition

This book presents state-of-the-art, authoritative chapters on contemporary issues in the broad areas of quantitative genetics, genomics and plant breeding. Section 1 (Chapters 2 to 12) emphasizes the application of genomics, and genome and epigenome editing techniques, in plant breeding; bioinformatics; quantitative trait loci mapping; and the latest approaches of examining and exploiting genotype-environment interactions. Section 2 (Chapters 13 to 20) represents the intersection of breeding, genetics and genomics. This section describes the use of cutting-edge molecular breeding and quantitative genetics techniques in wheat, rice, maize,

DNA Methyltransferases Role and Function

DNA Methyltransferases   Role and Function
  • Author : Albert Jeltsch,Renata Z. Jurkowska
  • Publisher : Springer
  • Release : 08 November 2016
GET THIS BOOK DNA Methyltransferases Role and Function

DNA methyltransferases are important enzymes in a broad range of organisms. Dysfunction of DNA methyltransferases in humans leads to many severe diseases, including cancer. This book focuses on the biochemical properties of these enzymes, describing their structures and mechanisms in bacteria, humans and other species, including plants, and also explains the biological processes of reading of DNA methylation and DNA demethylation. It covers many emerging aspects of the biological roles of DNA methylation functioning as an essential epigenetic mark and

Reprogramming the Genome CRISPR Cas based Human Disease Therapy

Reprogramming the Genome  CRISPR Cas based Human Disease Therapy
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 12 June 2021
GET THIS BOOK Reprogramming the Genome CRISPR Cas based Human Disease Therapy

Reprogramming the Genome: CRISPR-Cas-based Human Disease Therapy, presents the collation of chapters written by eminent scientists worldwide. CRISPR-Cas9 is a key technology for targeted genome editing and regulation in a number of organisms including mammalian cells. It is a rapid, simple, and cost-effective solution. CRISPR-Cas system has recently gained much scientific and public attention. This volume covers CRISPR-Cas9 based mammalian genome editing, creating disease models, cancer therapy, neurological, heredity, blood disorders, defective gene correction, stem cells therapy, epigenetic modifications, patents,

Chromatin and Epigenetics

Chromatin and Epigenetics
  • Author : Colin Logie,Tobias Aurelius Knoch
  • Publisher : BoD – Books on Demand
  • Release : 29 January 2020
GET THIS BOOK Chromatin and Epigenetics

Genomics has gathered broad public attention since Lamarck put forward his top-down hypothesis of 'motivated change' in 1809 in his famous book "Philosophie Zoologique" and even more so since Darwin published his famous bottom-up theory of natural selection in "The Origin of Species" in 1859. The public awareness culminated in the much anticipated race to decipher the sequence of the human genome in 2002. Over all those years, it has become apparent that genomic DNA is compacted into chromatin with a dedicated 3D

Neuroepigenomics in Aging and Disease

Neuroepigenomics in Aging and Disease
  • Author : Raul Delgado-Morales
  • Publisher : Springer
  • Release : 18 May 2017
GET THIS BOOK Neuroepigenomics in Aging and Disease

Epigenetic mechanisms (DNA modifications, histone alterations and non-coding RNAs) are crucial for transcriptional regulation and alterations of the “physiological epigenome” are increasingly associated with human diseases. During the last decade the emerging field of neuroepigenomics have started to impact tremendously in areas such learning and memory, addiction or neurodegeneration. This expert volume covers the role of epigenetic molecular mechanism in regulation of central nervous system’s function, one of the most exciting areas of contemporary molecular neuroscience. The book describes

Molecular Breeding in Wheat Maize and Sorghum

Molecular Breeding in Wheat  Maize and Sorghum
  • Author : Mohammad Anwar Hossain,Mobashwer Alam,Saman Seneweera,Sujay Rakshit,Robert J. Henry
  • Publisher : CABI
  • Release : 30 June 2021
GET THIS BOOK Molecular Breeding in Wheat Maize and Sorghum

The global population is projected to reach almost 10 billion by 2050, and food and feed production will need to increase by 70%. Wheat, maize and sorghum are three key cereals which provide nutrition for the majority of the world's population. Their production is affected by various abiotic stresses which cause significant yield losses. The effects of climate change also increase the frequency and severity of such abiotic stresses. Molecular breeding technologies offer real hope for improving crop yields. Although significant progress has

Omics Technologies for Sustainable Agriculture and Global Food Security Volume 1

Omics Technologies for Sustainable Agriculture and Global Food Security Volume 1
  • Author : Anirudh Kumar,Rakesh Kumar,Pawan Shukla,Manish K. Pandey
  • Publisher : Springer Nature
  • Release : 09 December 2021
GET THIS BOOK Omics Technologies for Sustainable Agriculture and Global Food Security Volume 1

Increasing world population, unpredictable climate and various kind of biotic and abiotic stresses necessitate the sustainable increase in crop production through developing improved cultivars possessing enhanced genetic resilience against all odds. An exploration of these challenges and near possible solution to improve yield is addressed in this book. It comprehensively and coherently reviews the application of various aspect of rapidly growing omics technology including genomics, proteomics, transcriptomics and metabolomics for crop development. It provides detailed examination of how omics can

Medicinal and Aromatic Plants

Medicinal and Aromatic Plants
  • Author : Tariq Aftab,Khalid Rehman Hakeem
  • Publisher : Academic Press
  • Release : 12 May 2020
GET THIS BOOK Medicinal and Aromatic Plants

Growing consumer interest in organic and herbal-based products has led to great demand in the botanicals industry in the past few years. However, the growing number of products utilizing medicinal and aromatic plants (MAPs) has threatened an estimated 9,000 medicinal plant species worldwide, making it critical to reevaluate their research and development, production, and utilization. Continuing advances in Omics methodologies and instrumentation are essential to understanding how plants cope with the dynamic nature of their growing environment, how yields and characteristics

Human Neural Stem Cells

Human Neural Stem Cells
  • Author : Leonora Buzanska
  • Publisher : Springer
  • Release : 12 September 2018
GET THIS BOOK Human Neural Stem Cells

This book summarizes early pioneering achievements in the field of human neural stem cell (hNSC) research and combines them with the latest advances in stem cell technology, including reprogramming and gene editing. The powerful potential of hNSC to generate and repair the developing and adult CNS has been confirmed by numerous experimental in vitro and in vivo studies. The book presents methods for hNSC derivation and discusses the mechanisms underlying NSC in vitro fate decisions and their in vivo therapeutic

Hormonal Control of Important Agronomic Traits

Hormonal Control of Important Agronomic Traits
  • Author : Chi-Kuang Wen,Yunde Zhao,Yong-Ling Ruan
  • Publisher : Frontiers Media SA
  • Release : 21 December 2018
GET THIS BOOK Hormonal Control of Important Agronomic Traits

One of the goals of plant science is to improve agricultural sustainability, increasing yield, food diversity, and nutrition, while minimizing the negative impact on our environment. In response to internal and external cues, plant hormones control various aspects of plant growth and development. The wealth of our knowledge on plant hormones shall greatly advance sustainable agriculture.