Sarcopenia

📒Sarcopenia ✍ Alfonso J. Cruz-Jentoft

Sarcopenia Book PDF
✏Book Title : Sarcopenia
✏Author : Alfonso J. Cruz-Jentoft
✏Publisher : John Wiley & Sons
✏Release Date : 2012-07-30
✏Pages : 364
✏ISBN : 9781118338056
✏Available Language : English, Spanish, And French

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✏Sarcopenia Book Summary : Edited and written by world experts in the field, this book definesand explains the clinical relevance of an important geriatricsyndrome: Sarcopenia. The book covers all recent scientificevidence and treatment options including interventions to improvesarcopenia, nutritional approaches to treat sarcopenia and thefuture of drug treatments.

Sarcopenia Age Related Muscle Wasting And Weakness Book PDF
✏Book Title : Sarcopenia Age Related Muscle Wasting and Weakness
✏Author : Gordon S. Lynch
✏Publisher : Springer Science & Business Media
✏Release Date : 2010-11-30
✏Pages : 479
✏ISBN : 9048197139
✏Available Language : English, Spanish, And French

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✏Sarcopenia Age Related Muscle Wasting and Weakness Book Summary : Some of the most serious consequences of aging are its effects on skeletal muscle. ‘Sarcopenia’, the progressive age-related loss of muscle mass and associated muscle weakness, renders frail elders susceptible to serious injury from sudden falls and fractures and at risk for losing their functional independence. Not surprisingly, sarcopenia is a significant public health problem throughout the developed world. There is an urgent need to better understand the neuromuscular mechanisms underlying age-related muscle wasting and to develop therapeutic strategies that can attenuate, prevent, or ultimately reverse sarcopenia. Significant research and development in academic and research institutions and in pharmaceutical companies is being directed to sarcopenia and to related health issues in order to develop and evaluate novel therapeutics. This book provides the latest information on sarcopenia from leading international researchers studying the cellular and molecular mechanisms underlying age-related changes in skeletal muscle and identifies strategies to combat sarcopenia and related muscle wasting conditions and neuromuscular disorders. The book provides a vital resource for researchers and practitioners alike, with information relevant to gerontologists, geriatricians, sports medicine physicians, physiologists, neuroscientists, cell biologists, endocrinologists, physical therapists, allied health and musculoskeletal practitioners, strength and conditioning specialists, athletic trainers, and students of the medical and biomedical sciences.

📒Sarcopenia ✍ Dominique Meynial-Denis

Sarcopenia Book PDF
✏Book Title : Sarcopenia
✏Author : Dominique Meynial-Denis
✏Publisher : CRC Press
✏Release Date : 2019-08-30
✏Pages : 352
✏ISBN : 9780429531972
✏Available Language : English, Spanish, And French

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✏Sarcopenia Book Summary : Sarcopenia: Molecular, Cellular, and Nutritional Aspects describes the progressive loss of skeletal muscle mass and strength, defined by Rosenberg in 1997 as a hallmark of aging and referred to as “sarcopenia.” As life expectancy continues to increase worldwide, sarcopenia has become a major public health issue. The condition worsens in the presence of chronic diseases accelerating its progression. Sarcopenia is not considered to be “a process of normative aging” but according to the International Classification of Disease, Tenth Revision, Clinical Modification (ICD-10-CM), as a disease. As sarcopenia is an ineluctable process, prevention and management are the only options to promote healthy aging; these actions should perhaps be taken during youth. Included in this book: · Features essential information on sarcopenia, its current definition, and molecular and cellular aspects of this disease · Discusses the development of physical frailty, a complication of sarcopenia, and predicts its occurrence in the older population · Presents alterations in muscle protein turnover and mitochondrial dysfunction in the aging process · Provides data on the negative involvement of sarcopenia in certain chronic diseases · Describes presbyphagia or age-related changes in the swallowing mechanism in older people · Details possible strategies to combat muscle wasting in healthy older adults and their limits This book features information collected from pioneers or experts on human aging from around the globe, including Europe, Brazil, Canada, Japan and the United States. It is a valuable source of information for nutritional scientists, medical doctors, sports scientists, food scientists, dietitians, students in these fields, and for anyone interested in nutrition. We hope this book provides a better understanding of sarcopenia which inevitably occurs with aging without weight loss. Moreover, this book will supply information outlining strategies to prevent or limit muscle wasting due to normal aging in order to promote successful aging.

📒Reverse Sarcopenia ✍ Joseph Tieri

Reverse Sarcopenia Book PDF
✏Book Title : Reverse Sarcopenia
✏Author : Joseph Tieri
✏Publisher : Simon and Schuster
✏Release Date : 2019-07-26
✏Pages : 128
✏ISBN : 9781612439181
✏Available Language : English, Spanish, And French

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✏Reverse Sarcopenia Book Summary : Take control of your physical and brain health with low-level strength training We all know that we lose muscle mass as we age. But did you know that sarcopenic obesity (a.k.a. being “skinny fat”) is linked to increasing your risk of developing dementia and/or Alzheimer’s? Not only is losing muscle bad for your body, it’s also bad for your brain. Don’t let muscle deterioration negatively affect your future. It’s time to take your physical and brain health into your own hands with strength training. This book is full of tips, techniques, and easy-to-follow strength-training routines to fight sarcopenia. From beginners to those already comfortable using weights, this book has solutions for everyone. Lose fat, improve muscle tone, and strengthen bones while guarding against sarcopenia and its negative impact on your body and your brain. This book makes it easy to regain the muscle mass you need to live a healthier and longer life.

The Prognostic Role Of Sarcopenia In Older Adults Undergoing Transcatheter Aortic Valve Replacement Book PDF
✏Book Title : The Prognostic Role of Sarcopenia in Older Adults Undergoing Transcatheter Aortic Valve Replacement
✏Author : Samuel Mamane
✏Publisher :
✏Release Date : 2018
✏Pages :
✏ISBN : OCLC:1086267544
✏Available Language : English, Spanish, And French

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✏The Prognostic Role of Sarcopenia in Older Adults Undergoing Transcatheter Aortic Valve Replacement Book Summary : "Background: Sarcopenia is the "biologic substrate of frailty" defined as an age-related syndrome characterized by the loss of skeletal muscle mass and a decrease in muscle function. Our objective was to explore the role of sarcopenia in the pre-procedural evaluation of older adults undergoing transcatheter aortic valve replacement (TAVR) and to determine its incremental prognostic value above established risk stratification tools.Methods: After reviewing the literature on sarcopenia in the peri-operative setting, focusing on the use of CT-scan skeletal muscle cross-sectional area as a measure of muscle mass, we developed a novel software tool and methodology for measuring psoas muscle area (PMA). In the first study, we validated this tool in the retrospective two-center Montreal-Munich cohort study evaluating the predictive role of PMA on outcomes in older adults undergoing TAVR. In the second study, we conducted a pre-planned analysis of the prospective multicentre FRAILTY-AVR cohort study to evaluate the prognostic value of sarcopenia as measured by a combination of low PMA and low lower extremity muscle performance, deriving a sarcopenia score including muscle mass and function.Results: PMA measured on single axial image at the level of the L4 vertebrae correlated well with psoas muscle volume (r=0.91, p

Frailty And Sarcopenia In Cirrhosis Book PDF
✏Book Title : Frailty and Sarcopenia in Cirrhosis
✏Author : Puneeta Tandon
✏Publisher : Springer
✏Release Date : 2020-11-29
✏Pages : 279
✏ISBN : 3030262286
✏Available Language : English, Spanish, And French

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✏Frailty and Sarcopenia in Cirrhosis Book Summary : This book provides a concise yet comprehensive overview of frailty and sarcopenia in the cirrhotic patient. The text presents a personalized approach to identifying cirrhotic patients at risk of higher morbidity and mortality due to frailty and sarcopenia. It reviews current and novel diagnostic methods, while spotlighting treatment and management strategies for frailty and sarcopenia. The book also focuses on special issues associated with these syndromes, such as the effect of gender, age, and ethnicity on frailty and sarcopenia, sarcopenic obesity, and frailty and sarcopenia after liver transplantation. Future considerations are outlined in the closing chapters, including emerging pharmacological and interventional therapies for these syndromes. Written by experts in the field, Frailty and Sarcopenia in Cirrhosis: The Basics, the Challenges, and the Future is a valuable resource for clinicians and practitioners who treat patients with cirrhosis.

Sarcopenia In Japanese Elderly With Diabetes Prevalence And Characteristics Book PDF
✏Book Title : Sarcopenia in Japanese Elderly with Diabetes Prevalence and Characteristics
✏Author : Moyama Shota
✏Publisher :
✏Release Date : 2017
✏Pages :
✏ISBN : OCLC:1163813408
✏Available Language : English, Spanish, And French

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✏Sarcopenia in Japanese Elderly with Diabetes Prevalence and Characteristics Book Summary : Background: Sarcopenia is a condition characterized by progressive and generalized loss of skeletal muscle mass and function; and causes serious health-related problems in the elderly with diabetes. Those aged u226565 years accounts for more than two third of patients with diabetes in Japan today, suggesting that a large fraction of Japanese individuals with diabetes suffer from sarcopenia. However, prevalence of sarcopenia and pre-sarcopenia among the elderly with diabetes in Japan remains unknown.Aims: The present study is designed to examine prevalence of sarcopenia in elderly Japanese patients with diabetes; and to find possible associations with severity of sarcopenia with dietary intake.Methods: From 2016 to 2017, we carried out a cross sectional study about 91 type 2 diabetes patients aged 65 and above (47 males and 44 females, mean age 72.7u00b15.5 years) without overt chronic diabetic complications. In all subjects, grip strength and body composition (SMI; skeletal muscle index, PBF; percent body fat) were measured using the digital hand dynamometer and the bioelectricity impedance measuring device (InBody s10). Based on the diagnostic criteria reported by Chen LK et al (2014), subjects were divided into 4 groups; sarcopenia group (Group S, loss of SMI and grip strength), pre-sarcopenia A group (Group PSa, loss of SMI only), pre-sarcopenia B group (Group PSb, loss of grip strength only), and non-sarcopenia group (Group NS, neither loss of SMI nor grip strength). We evaluated participant characteristics (age, body weight, SMI, PBF), dietary intake, glycemic control (HbA1c), and renal function (Creatinine, BUN, eGFR) among 4 groups.Results: The prevalence of sarcopenia was 11.0% (Group S, n=10), pre-sarcopenia was 27.0% (Group PSa, n=21; 23.0%, Group PSb, n=4; 4.0%), and the rest was 62.0% (Group NS, n=56). Ages in Group NS was the lowest among the groups. In addition, the body weight and SMI in 2 groups (Group S and PSa) were significantly lower than those in Group NS (p

📒Sarcopenia And Malnutrition In The Elderly ✍ Beatriz Lardiés-Sánchez

Sarcopenia And Malnutrition In The Elderly Book PDF
✏Book Title : Sarcopenia and Malnutrition in the Elderly
✏Author : Beatriz Lardiés-Sánchez
✏Publisher :
✏Release Date : 2017
✏Pages :
✏ISBN : OCLC:1154263309
✏Available Language : English, Spanish, And French

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✏Sarcopenia and Malnutrition in the Elderly Book Summary : Sarcopenia and malnutrition are both commonly occurring conditions in elderly population. As understood today, sarcopenia is a syndrome characterised by progressive and generalised loss of skeletal muscle mass, physical performance and/or strength, whereas malnutrition has been defined as a condition of an imbalance of energy, protein and other nutrients that can cause measurable negative effects. In many populations, malnutrition and sarcopenia are present simultaneously, and they appear clinically through a combination of decreased body weight and nutrient intake, along with a decrease in muscle mass and function. Moreover, malnutrition is one of the key pathophysiological causes of sarcopenia. Both entities result in numerous and substantial negative outcomes to the patients and the healthcare system, including decreased quality of life and functionality and increased healthcare costs, hospitalisation rates, morbidity and mortality. Early identification of sarcopenia would be of great clinical relevance because the loss of muscle mass and strength with ageing can be largely reversed by proper exercise and nutritional intervention. Clinicians should integrate nutritional assessment with sarcopenia screening for optimal evaluation of these two interrelated issues to help improve clinical outcomes.

Body Composition And Aging Book PDF
✏Book Title : Body Composition and Aging
✏Author : C. V. Mobbs
✏Publisher : Karger Medical and Scientific Publishers
✏Release Date : 2010
✏Pages : 197
✏ISBN : 9783805595216
✏Available Language : English, Spanish, And French

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✏Body Composition and Aging Book Summary : Increased adiposity and decreased muscle mass contribute substantially to age-dependent disease and disability. In particular age-related increase in adiposity is quickly becoming a major threat to public health throughout the world. Although the hypothesis that age-related changes in body composition are due to lifestyle choices alone is well accepted, it is a vast oversimplification. This volume reflects the current knowledge in this rapidly developing field of research. The first part of the book discusses the extent to which increased adiposity contributes to age-related diseases and longevity. The 'obesity paradox', describing the protective role of overweight in decreasing mortality while increasing pathology, is covered in depth. Further chapters address specific aspects of the regulation of energy balance during aging, including the effects of changes in food intake. Finally the causes and consequences of loss of muscle mass and age-related osteoporosis are examined. A valuable help for physicians treating elderly patients, this book will also be of great interest to researchers studying energy balance, muscle physiology, bone disease, and other aspects of aging.

The Prevalence Of Sarcopenia In Patients With Respiratory Failure Classified As Normally Nourished Using Computed Tomography And Subjective Global Assessment Book PDF
✏Book Title : The Prevalence of Sarcopenia in Patients With Respiratory Failure Classified as Normally Nourished Using Computed Tomography and Subjective Global Assessment
✏Author :
✏Publisher :
✏Release Date : 2014
✏Pages :
✏ISBN : OCLC:1051329296
✏Available Language : English, Spanish, And French

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✏The Prevalence of Sarcopenia in Patients With Respiratory Failure Classified as Normally Nourished Using Computed Tomography and Subjective Global Assessment Book Summary : Background : Declines in nutrition status and adverse body composition changes frequently occur in the critically ill. The objective of this cross-sectional study was to examine the prevalence of sarcopenia and its occurrence in patients classified as normal nourished using subjective global assessment (SGA). Methods : Exploiting diagnostic CT images, skeletal muscle mass at the L3 region was quantified and used to determine sarcopenia and its association with normal nutrition status in 56 patients with respiratory failure. Sarcopenia was defined as an L3 skeletal muscle index of ≤38.5 cm 2 /m 2 for women and ≤52.4 cm 2 /m 2 for men. CT imaging and SGA classifications completed within 14, 10 and 7 days of each other were analyzed to assess sarcopenia and the influence of time between scans on misclassification (ie, normal nourished and sarcopenic). Descriptive statistics were conducted. Results : The average patient was 59.2 (± 15.6) years old, admitted with sepsis/infection, an APACHE II score of 26 (± 8.0), and BMI of 28.3 (± 5.8). Sarcopenia and sarcopenic obesity were prevalent in a minimum of 56% and 24% of patients, respectively, depending on the number of days between CT imaging and SGA assessment. Misclassified individuals were predominantly male, minority and overweight or obese. Controlling for age, no significant differences were noted for patients classified as normal nourished vs malnourished by SGA for lumbar muscle cross-sectional, whole-body lean mass, or skeletal muscle index. Conclusions : Sarcopenia is highly prevalent among patients with respiratory failure requiring mechanical ventilation (MV) and not readily detected in patients classified as normal nourished using SGA.

Clinical Nutrition And Aging Book PDF
✏Book Title : Clinical Nutrition and Aging
✏Author : Chad Cox
✏Publisher : CRC Press
✏Release Date : 2017-10-02
✏Pages : 306
✏ISBN : 9781315359823
✏Available Language : English, Spanish, And French

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✏Clinical Nutrition and Aging Book Summary : This title includes a number of Open Access chapters. Sarcopenia—the loss of muscle mass and strength that occurs with advancing age—is a major health challenge, particularly in North America, Europe, and Japan, which have large aging populations. This compendium volume is a valuable addition to the existing literature, providing state-of-the-art information on the most effective prevention and treatment options. Included are research articles on nutrition management and the prevention of sarcopenia; protein therapy for sarcopenia; effect of exercise on sarcopenia; and other therapeutic strategies, including antioxidants and steroids.

📒Geriatric Nutrition ✍ John E. Morley

Geriatric Nutrition Book PDF
✏Book Title : Geriatric Nutrition
✏Author : John E. Morley
✏Publisher : CRC Press
✏Release Date : 2007-05-30
✏Pages : 600
✏ISBN : 9781420005493
✏Available Language : English, Spanish, And French

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✏Geriatric Nutrition Book Summary : In a vicious cycle, poor nutritional health leads to acute and chronic disease, and disease states are catastrophic to nutritional health. The magnitude of nutritional depletion from any cause depends to a large extent on the nutritional reserves an individual has accumulated over time. In our increasingly older population, nutritional reserves are

Understanding Cachexia Sarcopenia And Physical Exercise In Patients With Cancer Book PDF
✏Book Title : Understanding Cachexia Sarcopenia and Physical Exercise in Patients with Cancer
✏Author : Shinichiro Morishita
✏Publisher :
✏Release Date : 2017
✏Pages :
✏ISBN : OCLC:1154165785
✏Available Language : English, Spanish, And French

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✏Understanding Cachexia Sarcopenia and Physical Exercise in Patients with Cancer Book Summary : Many patients with cancer experience muscle wasting and weakness. Muscle wasting in patients with cancer can be caused by cachexia and sarcopenia. Both cachexia and sarcopenia involve inflammation and oxidative stress. However, they differ in the underlying mechanisms that lead to muscle wasting. Cachexia involves the release of inflammatory cytokines due to cancer, while sarcopenia involves inflammation due to aging. Physical exercise has shown effectiveness for improving physical function, ability, and quality of life (QOL) in patients with cancer cachexia. On the other hand, no studies have investigated the relationship between physical exercise and sarcopenia in elderly patients with cancer. Previous studies showed effectiveness for improving physical function in elderly patients with cancer. In the future, more studies are required on physical exercise in sarcopenic elderly patients with cancer.

📒Geriatric Physical Therapy Ebook ✍ Andrew A. Guccione

Geriatric Physical Therapy Ebook Book PDF
✏Book Title : Geriatric Physical Therapy eBook
✏Author : Andrew A. Guccione
✏Publisher : Elsevier Health Sciences
✏Release Date : 2011-03-07
✏Pages : 624
✏ISBN : 9780323072410
✏Available Language : English, Spanish, And French

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✏Geriatric Physical Therapy eBook Book Summary : Geriatric Physical Therapy offers a comprehensive presentation of geriatric physical therapy science and practice. Thoroughly revised and updated, editors Andrew Guccione, Rita Wong, and Dale Avers and their contributors provide current information on aging-related changes in function, the impact of these changes on patient examination and evaluation, and intervention approaches that maximize optimal aging. Chapters emphasize evidence-based content that clinicians can use throughout the patient management process. Six new chapters include: Exercise Prescription, Older Adults and Their Families, Impaired Joint Mobility, Impaired Motor Control, Home-based Service Delivery, and Hospice and End of Life. Clinically accurate and relevant while at the same time exploring theory and rationale for evidence-based practice, it’s perfect for students and practicing clinicians. It’s also an excellent study aid for the Geriatric Physical Therapy Specialization exam. Comprehensive coverage provides all the foundational knowledge needed for effective management of geriatric disorders. Content is written and reviewed by leading experts in the field to ensure information is authoritative, comprehensive, current, and clinically accurate. A highly readable writing style and consistent organization make it easy to understand difficult concepts. Tables and boxes organize and summarize important information and highlight key points for quick reference. A well-referenced and scientific approach provides the depth to understand processes and procedures. Theory mixed with real case examples show how concepts apply to practice and help you enhance clinical decision-making skills. Standard APTA terminology familiarizes you with terms used in practice. A new chapter, Exercise Prescription, highlights evidence-based exercise prescription and the role of physical activity and exercise on the aging process. A new chapter, Older Adults and Their Families, helps physical therapists understand the role spouses/partners and adult children can play in rehabilitation, from providing emotional support to assisting with exercise programs and other daily living activities. New chapters on Impaired Joint Mobility, Impaired Motor Control, Home-based Service Delivery, and Hospice and End of Life expand coverage of established and emerging topics in physical therapy. Incorporates two conceptual models: the Guide to Physical Therapist Practice, 2nd Edition, and the International Classification of Function, Disability, and Health (ICF) of the World Health Organization (WHO) with an emphasis on enabling function and enhancing participation rather than concentrating on dysfunction and disability A companion Evolve website includes all references linked to MEDLINE as well as helpful links to other relevant websites.

Postmenopausal Osteoporosis Basic And Clinical Concepts Book PDF
✏Book Title : Postmenopausal Osteoporosis Basic and Clinical Concepts
✏Author : Meeta
✏Publisher : JAYPEE BROTHERS PUBLISHERS
✏Release Date : 2013-12-15
✏Pages : 281
✏ISBN : 9789350908334
✏Available Language : English, Spanish, And French

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✏Postmenopausal Osteoporosis Basic and Clinical Concepts Book Summary : Postmenopausal osteoporosis falls in the preview of the gynecologists, rheumatologists, endocrinologists, family physicians, orthopedicians, surgeons, pediatricians, physiotherapists, nutritionists and dentists too. Osteoporosis is the most common bone disorder affecting humans. It is a skeletal disorder characterized by compromised bone strength, predisposing a person to an increased risk of fracture. The outcomes in morbidity and mortality can be devastating. Galaxy of distinguished contributors from India and different parts of the globe contributed according to their expertise in this fiel.

Brocklehurst S Textbook Of Geriatric Medicine And Gerontology Book PDF
✏Book Title : Brocklehurst s Textbook of Geriatric Medicine and Gerontology
✏Author : Howard M. Fillit
✏Publisher : Elsevier Health Sciences
✏Release Date : 2010-05-10
✏Pages : 1152
✏ISBN : 9781437720754
✏Available Language : English, Spanish, And French

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✏Brocklehurst s Textbook of Geriatric Medicine and Gerontology Book Summary : Popular with generations of practitioners, Brocklehurst's Textbook of Geriatric Medicine and Gerontology has been the definitive reference of choice in the field of geriatric care. The new 7th Edition, by Howard M. Fillit, MD, Kenneth Rockwood, MD, and Kenneth Woodhouse, carries on this tradition with an increased clinical focus and updated coverage to help you meet the unique challenges posed by this growing patient population. Consistent discussions of clinical manifestations, diagnosis, prevention, treatment, and more make reference quick and easy, while over 255 illustrations compliment the text to help you find what you need on a given condition. Examples of the latest imaging studies depict the effects of aging on the brain, and new algorithms further streamline decision making. Emphasizes the clinical relevance of the latest scientific findings to help you easily apply the material to everyday practice. Features consistent discussions of clinical manifestations, diagnosis, prevention, treatment, and more that make reference quick and easy. Includes over 255 illustrations—including algorithms, photographs, and tables—that compliment the text to help you find what you need on a given condition. Provides summary boxes at the end of each chapter that highlight important points. Features the work of an expert author team, now led by Dr. Howard M. Fillit who provides an American perspective to complement the book’s traditional wealth of British expertise. Includes an expanded use of algorithms to streamline decision making. Presents more color images in the section on aging skin, offering a real-life perspective of conditions for enhanced diagnostic accuracy. Includes examples of the latest imaging studies to help you detect and classify changes to the brain during aging. Offers Grade A evidence-based references keyed to the relevant text.

Frailty And Sarcopenia In The Colorectal Patient Book PDF
✏Book Title : Frailty and Sarcopenia in the Colorectal Patient
✏Author : Thomas Adam Dale MacLaine
✏Publisher :
✏Release Date : 2018
✏Pages :
✏ISBN : OCLC:1112372630
✏Available Language : English, Spanish, And French

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✏Frailty and Sarcopenia in the Colorectal Patient Book Summary :

Professional Personal Trainer Certification Course Book PDF
✏Book Title : Professional Personal Trainer Certification Course
✏Author : Joe Antouri
✏Publisher : AuthorHouse
✏Release Date : 2010-05
✏Pages : 328
✏ISBN : 9781438987606
✏Available Language : English, Spanish, And French

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✏Professional Personal Trainer Certification Course Book Summary : Basic Scientific Principles of weight resistance training for private trainers. The Private Trainers Association course is a curriculum divided among practical application training and academic experience. Online or home course study is available when purchasing this book. The course is recognized and endorsed worldwide in 180 countries.

Arresting Frailty And Sarcopenia In Cirrhosis Future Prospects Book PDF
✏Book Title : Arresting Frailty and Sarcopenia in Cirrhosis Future Prospects
✏Author :
✏Publisher :
✏Release Date : 2018
✏Pages :
✏ISBN : OCLC:1032197071
✏Available Language : English, Spanish, And French

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✏Arresting Frailty and Sarcopenia in Cirrhosis Future Prospects Book Summary : Abstract : Watch a video presentation of this article Watch the interview with the author.

📒Frailty And Sarcopenia ✍ Yannis Dionyssiotis

Frailty And Sarcopenia Book PDF
✏Book Title : Frailty and Sarcopenia
✏Author : Yannis Dionyssiotis
✏Publisher : BoD – Books on Demand
✏Release Date : 2017-08-30
✏Pages : 254
✏ISBN : 9789535134831
✏Available Language : English, Spanish, And French

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✏Frailty and Sarcopenia Book Summary : Frailty is considered a multisystem impairment that makes an individual vulnerable to external or internal stressors. Sarcopenia, the age-dependent loss of muscle mass and function, is proposed as the biological substrate and the pathway whereby the consequences of physical frailty develop. These syndromes are associated with a negative impact in quality of life and can lead to the occurrence of disability, institutionalization, and even mortality. The book focuses upon all the related aspects of frailty and sarcopenia and the new advancements in the related treatments including complex issues and research. It includes high-quality chapters in all related aspects for the syndromes of sarcopenia and frailty, which adversely affect the function and overall effectiveness of the musculoskeletal system and interventions to promote rehabilitation.

14 Sarcopenia Is Not A Predictor Of Increased Toxicity Or Impaired Chemotherapy Response In Metastatic Non Small Cell Lung Cancer Book PDF
✏Book Title : 14 SARCOPENIA IS NOT A PREDICTOR OF INCREASED TOXICITY OR IMPAIRED CHEMOTHERAPY RESPONSE IN METASTATIC NON SMALL CELL LUNG CANCER
✏Author : Chad Michael Glisch
✏Publisher :
✏Release Date : 2017
✏Pages :
✏ISBN : OCLC:1163824868
✏Available Language : English, Spanish, And French

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✏14 SARCOPENIA IS NOT A PREDICTOR OF INCREASED TOXICITY OR IMPAIRED CHEMOTHERAPY RESPONSE IN METASTATIC NON SMALL CELL LUNG CANCER Book Summary : Introduction Sarcopenia is a negative prognostic factor in cancer patients and is widely determined by computed tomography (CT) measurement of muscle attenuation at the L3 psoas level. Previously we established that higher percentage of muscle attenuation correlated with lower metastatic burden and improved survival in metastatic non-small cell lung cancer patients (mNSCLC.) Here, we aim to evaluate if larger proportion of low muscle attenuation can predict increased toxicity and impact chemotherapy response. Methods: We identified 182 patients with mNSCLC receiving systemic therapy. CT scan before treatment was used to measure muscle attenuation at the L3 psoas level. Increased toxicity was defined as dose reduction or discontinuation of therapy, hospital admission or death in cycle 1/2/3 unrelated to progression. Response was evaluated by CT scans after 2-3 cycles of therapy or per clinician documentation. The primary outcome was percentage of muscle attenuation and its relation to response. The secondary outcome was impact of muscle attenuation on toxicity.Results: Of the 171 patients with scans, 135 patients had responding disease. Lower performance status (PS) at scan predicted for response (p=0.031). On a multivariate analysis, increasing percentage of muscle attenuation did not predict for response (OR=1.224, 95% CI 0.724-2.069, p=0.45). 66 patients (37.5%) had dose reduction in Cycle 1/2/3 or stopped chemotherapy because of toxicity. There was no association with muscle attenuation and toxicity (OR=0.800, 95% CI 0.547-1.208, p=0.30).Conclusion: Variation in muscle composition demonstrated no reliable difference in outcomes; therefore, baseline muscle attenuation at L3 psoas level is not a predictor of chemotherapy toxicity and response.

Issues In Disability Rehabilitation Wound Treatment And Disease Management 2011 Edition Book PDF
✏Book Title : Issues in Disability Rehabilitation Wound Treatment and Disease Management 2011 Edition
✏Author :
✏Publisher : ScholarlyEditions
✏Release Date : 2012-01-09
✏Pages : 1409
✏ISBN : 9781464964589
✏Available Language : English, Spanish, And French

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✏Issues in Disability Rehabilitation Wound Treatment and Disease Management 2011 Edition Book Summary : Issues in Disability, Rehabilitation, Wound Treatment, and Disease Management: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Disability, Rehabilitation, Wound Treatment, and Disease Management. The editors have built Issues in Disability, Rehabilitation, Wound Treatment, and Disease Management: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Disability, Rehabilitation, Wound Treatment, and Disease Management in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Disability, Rehabilitation, Wound Treatment, and Disease Management: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Advances In Muscular Atrophy Research And Treatment 2012 Edition Book PDF
✏Book Title : Advances in Muscular Atrophy Research and Treatment 2012 Edition
✏Author :
✏Publisher : ScholarlyEditions
✏Release Date : 2012-12-26
✏Pages : 43
✏ISBN : 9781481616447
✏Available Language : English, Spanish, And French

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✏Advances in Muscular Atrophy Research and Treatment 2012 Edition Book Summary : Advances in Muscular Atrophy Research and Treatment / 2012 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Muscular Atrophy in a concise format. The editors have built Advances in Muscular Atrophy Research and Treatment / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Muscular Atrophy in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Muscular Atrophy Research and Treatment / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

From Sarcopenia To Frailty The Pathophysiological Basis And Potential Target Molecules Of Intervention Book PDF
✏Book Title : From Sarcopenia to Frailty The Pathophysiological Basis and Potential Target Molecules of Intervention
✏Author : Zhuowei Yu
✏Publisher :
✏Release Date : 2017
✏Pages :
✏ISBN : OCLC:1154277153
✏Available Language : English, Spanish, And French

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✏From Sarcopenia to Frailty The Pathophysiological Basis and Potential Target Molecules of Intervention Book Summary : Skeletal muscle is not only an endocrine organ but also one of core components of muscloskeletal system. Sarcopenia refers to a decline in the skeletal muscle mass and function. The former involves the size and number of changes in two types of myofibers, lower satellite cell density, and regeneration ability. The latter shows a loss of muscle strength. Frailty is a geriatric syndrome with multisystem impairment associated with increased vulnerability to stressors. Sarcopenia increases the risk of frailty and may be one of the major causes of physical frailty phenotype. Sarcopenia is also potentially associated with cognitive frailty phenotype. Aging might be the common underlying pathophysiology of sarcopenia and frailty. Therefore, there are some potential target molecules in aging-related signaling pathways that might be associated with sarcopenia and frailty. Nevertheless, sarcopenia can mediate metabolism and promote accelerate systemic aging, frailty, and age-related diseases by myokines in an endocrine manner. Lifestyle interventions (resistance exercise and dietary restriction) of gerontoscience are effective in the prevention of sarcopenia. Some pharmacological agents are registered in different phases of clinical trials for sarcopenia intervention. Phytochemicals, mTOR inhibitors, metformin and acarbose, NAD precursors, and sirtuin activators demonstrated that multiple target antiaging effects might also have preventive and therapeutic perspectives on sarcopenia and frailty.

Physical Performance And Muscle Mass In The Assessment Of Sarcopenia And Its Association With Receipt And Completion Of Planned Treatment In Non Small Cell Lung Cancer Book PDF
✏Book Title : Physical Performance and Muscle Mass in the Assessment of Sarcopenia and Its Association with Receipt and Completion of Planned Treatment in Non small Cell Lung Cancer
✏Author : Jemima Collins
✏Publisher :
✏Release Date : 2017
✏Pages :
✏ISBN : OCLC:1079337874
✏Available Language : English, Spanish, And French

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✏Physical Performance and Muscle Mass in the Assessment of Sarcopenia and Its Association with Receipt and Completion of Planned Treatment in Non small Cell Lung Cancer Book Summary :

Hepatic Encephalopathy An Update An Issue Of Clinics In Liver Disease E Book Book PDF
✏Book Title : Hepatic Encephalopathy An Update An Issue of Clinics in Liver Disease E Book
✏Author : Ravi Prakash
✏Publisher : Elsevier Health Sciences
✏Release Date : 2012-02-28
✏Pages : 196
✏ISBN : 9781455742905
✏Available Language : English, Spanish, And French

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✏Hepatic Encephalopathy An Update An Issue of Clinics in Liver Disease E Book Book Summary : A very hot topic at the 2010 AASLD meeting, hepatic encephalopathy is being brought to the Clinics in Liver Disease for the very first time by top experts, Dr. Mullen and Dr. Prakash. Authors have written articles that fully discuss the clinical aspects of hepatic encephalopathy (HE). Articles presented include History, Nomenclature and Classification; Theories involved in the pathogenesis of HE; Clinical Assessment and utility of clinical scales for semi-quantification of Overt HE; Assessment of Minimal HE ( with emphasis on computerized psychometric tests); Brain Imaging and HE; Management of Overt HE; Management of Minimal HE; Nutritional Interventions for HE; TIPS and HE; Liver Transplantation and Reversibility of HE; Minimal HE and Driving; and HE and Quality of Life.

Association Of Sarcopenia With Carotid Intima Media Thickness In Korean Male Patients With Type 2 Diabetes Book PDF
✏Book Title : Association of Sarcopenia with Carotid Intima media Thickness in Korean Male Patients with Type 2 Diabetes
✏Author : Shin Jang Yel
✏Publisher :
✏Release Date : 2017
✏Pages :
✏ISBN : OCLC:1163809005
✏Available Language : English, Spanish, And French

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✏Association of Sarcopenia with Carotid Intima media Thickness in Korean Male Patients with Type 2 Diabetes Book Summary : Sarcopenia and atherosclerosis is age-related disorders and its prevalence is common in individuals with type 2 diabetes. Several epidemiologic studies proposed that sarcopenia was associated with central obesity, insulin resistance, and type 2 diabetes. However, there was only few studies for investigating associations between sarcopenia and atherosclerosis. In this study we examined relationships of sarcopenia with carotid intima-media thickness (CIMT) in Korean male patients with type 2 diabetes.A total of 262 male subjects with type 2 diabetes were enrolled. B-mode ultrasound was used for measuring CIMT. High CIMT was defined as u2265 75 percentiles of maximum IMT in common carotid artery. Appendicular skeletal muscle mass (ASM) was assessed using dual energy X-ray absorptiometry (DEXA). We defined sarcopenia as follows: ASM (kg)/body mass index (BMI: kg/m2)

Geriatric Medicine An Issue Of Medical Clinics Of North America E Book Book PDF
✏Book Title : Geriatric Medicine An Issue of Medical Clinics of North America E Book
✏Author : John E. Morley
✏Publisher : Elsevier Health Sciences
✏Release Date : 2011-05-31
✏Pages : 240
✏ISBN : 9781455712410
✏Available Language : English, Spanish, And French

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✏Geriatric Medicine An Issue of Medical Clinics of North America E Book Book Summary : With the projected shortage of geriatricians over the next many years, it is essential for every internist and primary care physician to be equipped with the most current information and clinical skills for the treatment of older adults. This edition of Medical Clinics of North America brings the reader up to date on important issues in geriatrics including the following: treatment strategies for sarcopenia and frailty; congestive heart failure; revitalizing the aged brain; nutritional strategies for aging successfully; falls, osteoporosis and hip fractures; late-life Hypogonadism; hypertension in older persons; incontinence; delirium; weight loss; nursing homes and the physician; and diabetes and insulin resistance in older persons.

📒Bending The Aging Curve ✍ Joseph F. Signorile

Bending The Aging Curve Book PDF
✏Book Title : Bending the Aging Curve
✏Author : Joseph F. Signorile
✏Publisher : Human Kinetics
✏Release Date : 2011
✏Pages : 314
✏ISBN : 9780736074452
✏Available Language : English, Spanish, And French

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✏Bending the Aging Curve Book Summary : "Bending the Aging Curve" provides fitness professionals with a multifaceted periodized training program specifically for older adults. You will learn to use tests to diagnose your clients' needs and then prescribe training cycles with the appropriate mix of work, active recovery, and skill practice to maximize functional improvements.

Sarc F A Symptom Scale For Screening Sarcopenia Among Older Diabetic And Pre Diabetic Patients Book PDF
✏Book Title : SARC F A Symptom Scale for Screening Sarcopenia Among Older Diabetic and Pre diabetic Patients
✏Author : Huyen Thi Vu
✏Publisher :
✏Release Date : 2017
✏Pages :
✏ISBN : OCLC:1163848884
✏Available Language : English, Spanish, And French

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✏SARC F A Symptom Scale for Screening Sarcopenia Among Older Diabetic and Pre diabetic Patients Book Summary : Background and aims: Some of the mechanisms of the development of sarcopenia are also closely related with the pathogenesis of diabetes. Hyperglycemia and diabetic complications were associated with increased risk of sarcopenia . The aim was to evaluate the screening value of SARC-F among diabetic and pre-diabetic older patients.Materials and Methods: A cross-sectional study was conducted in Vietnam among diabetic and pre-diabetic patients aged 60 years or above. Dual-energy X-ray Absorptiometry device, hand grip strength test and 4-meters walking test were used to assess the muscle mass, muscle strength and physical performance, respectively. The European Working Group for Sarcopenia modified (weakness was defined by the lowest quintile of hand grip strength adjusted for BMI and gender) was applied as the u201cgold standardu201d. SARC-F was a simple tool comprising five assessment items (strength, assistance in walking, raise from a chair, climb stairs, falls). The patients having total SARC-F score u22654 were classified as sarcopenia. The validity and accuracy of the screening tool were evaluated. Results: A total of 470 patients were recruited (265 diabetic and 205 pre-diabetic patients), mean age 72.5(8.2) years, 64.5% female. Prevalence of sarcopenia according to SARC-F scale among diabetic and pre-diabetic patients was 55.9% and 49.8%, respectively. The sensitivity and specificity of this screening tool among patients with diabetes/pre-diabetes were 60.3 - 61.1% and 74.4 - 83.7%, respectively. SARC-F had high Positive Predictive Value (92.2 - 93.2%). But low Negative Predictive Value (24.8 - 39.8%) was documented. The AUCs of SARC-F in patients with diabetes and pre-diabetes were 0.752 and 0.761, respectively. Diabetic/pre-diabetic participants having SARC-Fu22654 had significantly higher risk of fall and disabilities than those have SARC-F