Resident Stem Cells And Regenerative Therapy

📒Resident Stem Cells And Regenerative Therapy ✍ Regina Coeli dos Santos Goldenberg

Resident Stem Cells And Regenerative Therapy Book PDF
✏Book Title : Resident Stem Cells and Regenerative Therapy
✏Author : Regina Coeli dos Santos Goldenberg
✏Publisher : Academic Press
✏Release Date : 2012-12-31
✏Pages : 304
✏ISBN : 9780123914415
✏Available Language : English, Spanish, And French

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✏Resident Stem Cells and Regenerative Therapy Book Summary : In the last 3 decades, stem cells have greatly impacted the scientific and lay communities, providing huge advances in the treatment of devastating human diseases, including myocardial infarction, diabetes, muscular dystrophy, cystic fibrosis, cirrhosis, and osteoporosis. Alongside debates of induced pluripotent stem cells and embryonic stem cells has been the discovery of adult stem cells in many different tissues. While these organ resident or progenitor stem cells offer prospects to contribute to tissue regeneration, they also present challenges because of the complexity of organ structures. This book will present the main findings to date and the important factors to be considered when considering resident stem cells in regenerative therapies. Chapters on cardiac, brain, neural, liver, kidney, skeletal muscle, bone, pancreatic, skin, and lung resident stem cells will assist in defining the level of success that has been achieved and the direction for the road ahead. With contributions from leading laboratories, open questions related to resident stem cells and regenerative therapies will also be presented for debate. Highlights basic research in tissue specific stem cells, experiments with animal models and clinical trials that are transforming the field of regeneration Provides a clear understanding of endogenous stem cells, their role in current regenerative therapies, and prospects for future research Reports on the main-stream clinical approaches and in vivo experiments published in primary literature to help categorizes the advances in various aspects of regenerative therapy and illustrate opportunities for clinical applications

Exam Prep For Resident Stem Cells And Regenerative Therapy Book PDF
✏Book Title : Exam Prep for Resident Stem Cells and Regenerative Therapy
✏Author :
✏Publisher :
✏Release Date :
✏Pages :
✏Available Language : English, Spanish, And French

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✏Exam Prep for Resident Stem Cells and Regenerative Therapy Book Summary :

The Promises And Challenges Of Regenerative Medicine Book PDF
✏Book Title : The Promises and Challenges of Regenerative Medicine
✏Author : John Morser
✏Publisher : Springer Science & Business Media
✏Release Date : 2005-07-06
✏Pages : 136
✏ISBN : 3540234810
✏Available Language : English, Spanish, And French

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✏The Promises and Challenges of Regenerative Medicine Book Summary : With the excitement in the research and clinical communities over the potential of regenerative medicine, it is hoped that novel therapies will be developed to target intractable degenerative diseases. In this book, leading experts in the field present the latest advances in stem cell research. It discusses the analysis and use of stem cells in basic biology but also their application in clinical practice and is therefore unique by combining basic and applied approaches.

Extracellular Matrix Enhances Therapeutic Effects Of Stem Cells In Regenerative Medicine Book PDF
✏Book Title : Extracellular Matrix Enhances Therapeutic Effects of Stem Cells in Regenerative Medicine
✏Author : Yan Nie
✏Publisher :
✏Release Date : 2016
✏Pages :
✏ISBN : OCLC:1154176925
✏Available Language : English, Spanish, And French

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✏Extracellular Matrix Enhances Therapeutic Effects of Stem Cells in Regenerative Medicine Book Summary : Stem cell therapy is a promising option for regenerative of injured or diseased tissues. However, the extremely low survival and engraftment of transplanted cells and the obviously inadequate recruitment and activation of the endogenous resident stem cells are the major challenges for stem cell therapy. Fortunately, recent progresses show that extracellular matrix (ECM) could not only act as a spatial and mechanical scaffold to enhance cell viability but also provide a supportive niche for engraftment or accelerating stem cell differentiation. These findings provide a new approach for increasing the efficiency of stem cell therapy and may lead to substantial changes in cell administration. In order to take a giant stride forward in stem cell therapy, we need to know much more about how the ECM affects cell behaviours. In this chapter, we provide an overview of the influence of ECM on regulating stem cell maintenance and differentiation. Moreover, the enhancement of supportive microenvironment function of natural or synthetic ECMs in stem cell therapy is discussed.

Stem Cell Biology And Regenerative Medicine In Ophthalmology Book PDF
✏Book Title : Stem Cell Biology and Regenerative Medicine in Ophthalmology
✏Author : Stephen Tsang
✏Publisher : Springer Science & Business Media
✏Release Date : 2012-12-09
✏Pages : 188
✏ISBN : 9781461454939
✏Available Language : English, Spanish, And French

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✏Stem Cell Biology and Regenerative Medicine in Ophthalmology Book Summary : Patient specific and disease specific stem cell lines have already introduced groundbreaking advances into the research and practice of ophthalmology. This volume provides a comprehensive and engaging overview of the latest innovations in the field. Twelve chapters discuss the fastest growing areas in ophthalmological stem cell research, from disease modelling, drug screening and gene targeting to clinical genetics and regenerative treatments. Innovative results from stem cell research of the past decade are pointing the way toward practicable treatments for retinitis pigmentosa, age related macular degeneration, and Stargardt disease. What future directions will stem cell research take? Researchers, graduate students, and fellows alike will find food for thought in this insightful guide tapping into the collective knowledge of leaders in the field. Stem Cells in Ophthalmology is part of the Stem Cells in Regenerative Medicine series dedicated to discussing current challenges and future directions in stem cell research.

Frontiers In Stem Cell And Regenerative Medicine Research Book PDF
✏Book Title : Frontiers in Stem Cell and Regenerative Medicine Research
✏Author : Atta-ur Rahman
✏Publisher : Bentham Science Publishers
✏Release Date : 2017-05-11
✏Pages : 253
✏ISBN : 9781681084756
✏Available Language : English, Spanish, And French

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✏Frontiers in Stem Cell and Regenerative Medicine Research Book Summary : Stem cell and regenerative medicine research is a hot area of research which promises to change the face of medicine as it will be practiced in the years to come. Challenges in the 21st century to combat diseases such as cancer, Alzheimer and related diseases may well be addressed employing stem cell therapies and tissue regeneration. Frontiers in Stem Cell and Regenerative Medicine Research is essential reading for researchers seeking updates in stem cell therapeutics and regenerative medicine. The fifth volume of this series features reviews on vascular regeneration, neuronal tissue grafting in animal CNS disease models, template mediated biomineralization in bones, corneal endothelium differentiation and stem cell uses for managing hepatocellular carcinoma.

📒Regenerating The Heart ✍ Ira S. Cohen

Regenerating The Heart Book PDF
✏Book Title : Regenerating the Heart
✏Author : Ira S. Cohen
✏Publisher : Springer Science & Business Media
✏Release Date : 2011-03-23
✏Pages : 558
✏ISBN : 1617790214
✏Available Language : English, Spanish, And French

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✏Regenerating the Heart Book Summary : Medical research made huge strides in treating heart disease in the 20th century, from drug-eluding stents to automatic internal defibrillators. Public awareness of the dangers of heart disease has never been more pervasive. Now, though, ten years into a new millennium, scientists are gearing up for the next great challenges in tackling this pervasive condition. Cell therapy is going to be a key weapon in the fight against heart disease. It has the potential to address many cardiovascular conditions. From heart failure to atrioventricular nodal dysfunction, the young but promising field of cell therapy is set to play a significant role in developing the cures that the upcoming decades of hard work will yield. Regenerating the Heart: Stem Cells and the Cardiovascular System organizes the field into a digestible body of knowledge. Its four sections cover mechanical regeneration, electrical regeneration, cardiac tissues and in vivo stem cell therapies. An array of talented researchers share the fruits of their labors, with chapters covering such crucial issues as the cardiogenic potential of varying stem cell types, the ways in which they might be used to tackle arrhythmias, their possible application to biological replacements for cardiac tissues such as valves, and the varying approaches used in the in vivo evaluation of stem cell therapies, including methods of delivering stem cells to the myocardium. This comprehensive survey of an area of research with such exciting potential is an invaluable resource both for veteran stem cell researchers who need to monitor fresh developments, and for newly minted investigators seeking inspirational examples.

Regenerative Medicine And Stem Cell Therapy For The Eye Book PDF
✏Book Title : Regenerative Medicine and Stem Cell Therapy for the Eye
✏Author : Brian G. Ballios
✏Publisher : Springer
✏Release Date : 2019-02-18
✏Pages : 212
✏ISBN : 9783319980805
✏Available Language : English, Spanish, And French

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✏Regenerative Medicine and Stem Cell Therapy for the Eye Book Summary : This book provides an overview of the types, sources, and applications of stem cells in regenerating various ocular tissues, with a perspective on both potential applications of stem cells and possible challenges. The scope of the chapters include both preclinical and clinical applications, including stem cell-derived therapies based on endogenous tissue repair; stem cell transplantation and cell replacement therapy; gene therapy; and in vitro disease modelling. Additionally, the volume presents applications in both anterior and posterior ocular disease, with a particular focus on diseases of the ocular surface, cornea, limbus, and retina, including inherited retinal dystrophies as well as acquired diseases, such as age-related macular degeneration. Regenerative Medicine and Stem Cell Therapy for the Eye is an ideal book for advanced researchers in stem cell and ocular biology as well as clinical ophthalmologists, and will be of interest to readers with backgrounds in developmental biology and bioengineering. This book also Skillfully reviews cutting-edge advances in stem cell biology as applied to regenerative medicine and ocular disease Provides expert viewpoints on key hurdles and challenges to successful implementation of stem cell-derived therapies in the clinical domain Offers a multi-disciplinary, broad understanding of cell-based therapies for ocular diseases by incorporating perspectives from biomedical scientists, physicians, and engineers Examines the connection between cell therapy and gene editing, in particular relation to ocular disease

Handbook Of Intelligent Scaffolds For Tissue Engineering And Regenerative Medicine Book PDF
✏Book Title : Handbook of Intelligent Scaffolds for Tissue Engineering and Regenerative Medicine
✏Author : Gilson Khang
✏Publisher : CRC Press
✏Release Date : 2017-06-26
✏Pages : 1440
✏ISBN : 9789814745130
✏Available Language : English, Spanish, And French

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✏Handbook of Intelligent Scaffolds for Tissue Engineering and Regenerative Medicine Book Summary : Millions of patients suffer from end-stage organ failure or tissue loss annually, and the only solution might be organ and/or tissue transplantation. To avoid poor biocompatibility–related problems and donor organ shortage, however, around 20 years ago a new, hybridized method combining cells and biomaterials was introduced as an alternative to whole-organ and tissue transplantation for diseased, failing, or malfunctioning organs—regenerative medicine and tissue engineering. This handbook focuses on all aspects of intelligent scaffolds, from basic science to industry to clinical applications. Its 10 parts, illustrated throughout with excellent figures, cover stem cell engineering research, drug delivery systems, nanomaterials and nanodevices, and novel and natural biomaterials. The book can be used by advanced undergraduate- and graduate-level students of stem cell and tissue engineering and researchers in macromolecular science, ceramics, metals for biomaterials, nanotechnology, chemistry, biology, and medicine, especially those interested in tissue engineering, stem cell engineering, and regenerative medicine.

📒Adult Stem Cells ✍ Donald G. Phinney

Adult Stem Cells Book PDF
✏Book Title : Adult Stem Cells
✏Author : Donald G. Phinney
✏Publisher : Springer Science & Business Media
✏Release Date : 2011-02-11
✏Pages : 279
✏ISBN : 1617790028
✏Available Language : English, Spanish, And French

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✏Adult Stem Cells Book Summary : This is comprehensive overview of a vital area of scientific enquiry, which covers a broad spectrum of issues. With contributions from some of the key researchers in the field, Adult Stem Cells: Biology and Methods of Analysis offers readers a historical perspective as well as unique insights into cutting-edge thoughts. The volume contextualizes the recent discovery of stem/progenitor cell populations resident in many adult tissues and organs. It confronts the complexities scientists face in trying to validate these cells, while it also describes and critically evaluates the methods currently used to assess stem cell self-renewal. The chapters also seek to distinguish this process from other aspects of cell survival, such as the regulation of life span, senescence, and immortalization at a molecular level. The monograph begins with a section that examine the basic biology of adult stem cells, including chapters on the emerging role of microRNAs in regulating their fate and the molecular mechanisms that govern their self-renewal, the book moves on to analyze the varying methodologies employed in characterizing these elusive elements of our genetic make-up. The second section details in-vivo lineage tracing of tissue-specific stem cells, explores the neural stem cell paradigm, and considers the function of ABC transporters and aldehyde dehydrogenase in adult stem-cell biology. The final section shifts the focus to the life-span regulation and immortalization and features a chapter on the cancer stem cell paradigm. This is an authoritative volume on one of the frontiers of genetic research, and will serve as a valuable resource, not just for established scientists but also for those now entering the field of stem cell biology.

📒Sabiston Textbook Of Surgery E Book ✍ Courtney M. Townsend

Sabiston Textbook Of Surgery E Book Book PDF
✏Book Title : Sabiston Textbook of Surgery E Book
✏Author : Courtney M. Townsend
✏Publisher : Elsevier Health Sciences
✏Release Date : 2012-02-17
✏Pages : 2152
✏ISBN : 9781455738083
✏Available Language : English, Spanish, And French

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✏Sabiston Textbook of Surgery E Book Book Summary : Sabiston Textbook of Surgery is your ultimate foundation for confident surgical decision making. Covering the very latest science and data affecting your treatment planning, this esteemed medical reference helps you make the most informed choices so you can ensure the best outcome for every patient. Consult it on the go with online access at, and get regular updates on timely new findings and advances. Overcome tough challenges, manage unusual situations, and avoid complications with the most trusted advice in your field. Prepare for tests and exams with review questions and answers online. Keep up with the very latest developments concerning abdominal wall reconstruction, tumor immunology and immunotherapy, peripheral vascular disease, regenerative medicine, liver transplantation, kidney and pancreas transplantation, small bowel transplantation, the continually expanding role of minimally invasive and robotic surgery, and many other rapidly evolving areas. Weigh your options by reviewing the most recent outcomes data and references to the most current literature.

Role Of Stem Cells In Skeletal Muscle Development Regeneration Repair Aging And Disease Book PDF
✏Book Title : Role of Stem Cells in Skeletal Muscle Development Regeneration Repair Aging and Disease
✏Author : Pura Muñoz-Cánoves
✏Publisher : Frontiers Media SA
✏Release Date : 2016-06-29
✏Pages :
✏ISBN : 9782889198665
✏Available Language : English, Spanish, And French

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✏Role of Stem Cells in Skeletal Muscle Development Regeneration Repair Aging and Disease Book Summary : Adult stem cells are responsible for tissue regeneration and repair throughout life. Their quiescence or activation are tightly regulated by common signalling pathways that often recapitulate those happening during embryonic development, and thus it is important to understand their regulation not only in postnatal life, but also during foetal development. In this regard, skeletal muscle is an interesting tissue since it accounts for a large percentage of body mass (about 40%), it is highly amenable to intervention through exercise and it is also key in metabolic and physiological changes underlying frailty susceptibility in the elderly. While muscle-resident satellite cells are responsible for all myogenic activity in physiological conditions and become senescent in old age, other progenitor cells such as mesoangioblasts do seem to contribute to muscle regeneration and repair after tissue damage. Similarly, fibro-adipogenic precursor cells seem to be key in the aberrant response that fills up the space left from atrophied muscle mass and which ends up with a dysfunctional muscle having vast areas of fatty infiltration and fibrosis. The complex interplay between these stem/progenitor cell types and their niches in normal and pathological conditions throughout life are the subjects of intense investigation. This eBook highlights recent developments on the role of stem cells in skeletal muscle function, both in prenatal and postnatal life, and their regulation by transcriptional, post-transcriptional and epigenetic mechanisms. Additionally, it includes articles on interventions associated with exercise, pathological changes in neuromuscular diseases, and stem cell aging.

📒Perinatal Stem Cells ✍ Curtis L. Cetrulo, Jr.

Perinatal Stem Cells Book PDF
✏Book Title : Perinatal Stem Cells
✏Author : Curtis L. Cetrulo, Jr.
✏Publisher : John Wiley & Sons
✏Release Date : 2010-01-05
✏Pages : 267
✏ISBN : 0470480130
✏Available Language : English, Spanish, And French

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✏Perinatal Stem Cells Book Summary :

Role Of Stem Cells And Extracellular Matrix In The Regeneration Of Skeletal Muscle Book PDF
✏Book Title : Role of Stem Cells and Extracellular Matrix in the Regeneration of Skeletal Muscle
✏Author : Andrew Dunn
✏Publisher :
✏Release Date : 2018
✏Pages :
✏ISBN : OCLC:1154220561
✏Available Language : English, Spanish, And French

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✏Role of Stem Cells and Extracellular Matrix in the Regeneration of Skeletal Muscle Book Summary : Adult skeletal muscle has a remarkable capacity to initiate a rapid and extensive repair process after damage due to injury or degenerative disease. Although satellite cells are the primary skeletal muscle stem cells, there are many reports of non-satellite cell populations with myogenic capacity resident within skeletal muscle. The activity of muscle-resident stem cells during the regeneration process is tightly controlled through the dynamic interactions between intrinsic factors within the cells and extrinsic factors constituting the muscle stem cell niche. The extracellular matrix (ECM) in skeletal muscle plays an integral role in force transmission, structural maintenance, and regulation of stem cell niche. ECM interacts with stem cells either directly by binding cell surface receptors or indirectly through growth factor presentation, and maintains a balance between their quiescence, self-renewal, and differentiation. These interactions are reciprocal since the stem cells can remodel the niche and secrete or degrade ECM components. Natural ECM scaffolds, derived from decellularized tissues can influence stem cell activity both in vitro and in vivo and are widely being investigated for skeletal muscle repair. In this chapter, we discuss the regenerative potential of stem cell populations and ECM bioscaffolds in the treatment of skeletal muscle injury and disease.

Regenerative Medicine Stem Cells And The Liver Book PDF
✏Book Title : Regenerative Medicine Stem Cells and the Liver
✏Author : David C. Hay
✏Publisher : CRC Press
✏Release Date : 2012-04-12
✏Pages : 200
✏ISBN : 9781466513853
✏Available Language : English, Spanish, And French

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✏Regenerative Medicine Stem Cells and the Liver Book Summary : The regenerative capacity of the liver has been recognized for centuries, but when it is overwhelmed by insulting stimuli or is chronically damaged, its regenerative capability is substantially reduced or lost. Researchers have been working to find solutions to cure failing human liver function. Given the ability of stem cells to self- renew and differentiate into specialized cell liver types, they represent an attractive strategy to replace lost liver function. This book begins by outlining the complex nature of human liver disease and proceeds to examine the potential that stem cell-based approaches have to offer.

Stem Cell Biology And Regenerative Medicine Book PDF
✏Book Title : Stem Cell Biology and Regenerative Medicine
✏Author : Charles Durand
✏Publisher : River Publishers
✏Release Date : 2015-01-01
✏Pages : 760
✏ISBN : 9788793237070
✏Available Language : English, Spanish, And French

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✏Stem Cell Biology and Regenerative Medicine Book Summary : The study of stem cell biology is under intensive investigations. Because stem cells have the unique capability to self-renew and differentiate into one or several cell types, they play a critical role in development, tissue homeostasis and regeneration. Stem cells also constitute promising cell candidates for cell therapy. The aim of this book is to provide an accurate knowledge on stem cell biology and regenerative medicine. This book will cover many topics in the field and is based on seminars given by recognized scientists involved the international master program on stem cell biology at the University Pierre and Marie Curie (UPMC) in Paris. Content Preface. Pierre Charbord and Charles Durand. 1) General concepts 1.Stem cell concepts. Charles Durand and Pierre Charbord. 2.Transcriptional regulation in stem cells. Eric Soler and Frank Grosveld. 3.DNA repair in stem cells. Leyla Vahidi Ferdousi and Miria Ricchetti. 4. Stem cells and epigenetic regulation. Emma L. Walton and Claire Francastel. 5. Hydra and the evolution of stem cells. Alexander Klimovich, Anna Marei Böhm and Thomas C.G. Bosch. 6. Ontogeny of stem cells. Thierry Jaffredo. 7. Regeneration in anamniotic vertebrates. Dunja Knapp. 8. Computational models of spatio-temporal stem cell organization. Peter Buske and Joerg Galle. 2) Pluripotent stem cells 9. X chromosome inactivation in stem cells and development. Agnese Loda, Friedemann Loos and Joost Gribnau. 10. Molecular machinery of reprogramming. Romain Desprat, Ollivier Milhavet and Jean-Marc Lemaitre. 11. Modeling human genetic disorders using induced pluripotent stem cells. Franck Lebrin. 3) Adult stem cells 12. Developmental biology of hematopoietic stem cells : Cellular aspects. Laurent Yvernogeau, Jean-Charles Boisset and Catherine Robin. 13. Developmental biology of haematopoietic stem cells: Cell intrinsic and extrinsic regulators of their emergence. Katrin Ottersbach. 14. Biology of hematopoietic stem cells in the adult. Marie-Laure Arcangeli, Rima Haddad, Francoise Pflumio. 15. Epithelial stem cells in the skin. Romain Fontaine, Mathieu Castela and Selim Aractingi. 16. Skeletal muscle stem cells. Elisa Negroni, Maximilien Bencze, Stéphanie Duguez, Gillian Butler-Browne and Vincent Mouly. 17. Mammary stem cells. Marie-Ange Deugnier, Marisa M. Faraldo and Marina A. Glukhova. 18. Intestinal stem cells. Silvia Fre. 19. Neural stem cells. Nathalie Kubis and Martin Catala. 20. Dental stem cells. Anne Poliard. 21. Bone marrow Mesenchymal Stem Cells: from stemness to stromal property of hematopoietic support. Pierre Charbord and Bruno Delorme. 22. Retinal stem cells. Olivier Goureau, Angélique Terray, Katherine S. Matho, Sacha Reichman, and Gael Orieux. 4) Stem cell-related diseases and therapy using stem cells 23. Leukemic stem cells: what the concept brings to disease and patient management. Berent Lunden and Christine Chomienne. 24. Stem cells for cardiac repair. Philippe Menasché. 25. Stem cells for red blood cell production. Christelle Mazurier, Guillaume F Rousseau, Luc Douay and Hélène Lapillonne. 26. Prospectives for therapy with stem cells in skeletal muscular diseases. Maximilien Bencze, Elisa Negroni, Vincent Mouly and Gillian Butler-Browne. 5) Regulatory and philosophical aspects 27. Legal framework for research on Human Embryonic Stem Cells in France and in Europe. Arnaud de Guerra, Emmanuelle Prada-Bordenave 28. Stem cell epistemological issues. Lucie Laplane. 29. Future outlook. Pierre Charbord and Charles Durand.

Stem Cell Research On Cardiology Book PDF
✏Book Title : Stem Cell Research on Cardiology
✏Author : Robert David
✏Publisher :
✏Release Date : 2020-10
✏Pages : 356
✏ISBN : 3039431927
✏Available Language : English, Spanish, And French

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✏Stem Cell Research on Cardiology Book Summary : Even today, cardiovascular diseases are the main cause of death worldwide, and therapeutic approaches are very restricted. Due to the limited regenerative capabilities of terminally differentiated cardiomyocytes post injury, new strategies to treat cardiac patients are urgently needed. Post myocardial injury, resident fibroblasts begin to generate the extracellular matrix, resulting in fibrosis, and finally, cardiac failure. Recently, preclinical investigations and clinical trials raised hope in stem cell-based approaches, to be an effective therapy option for these diseases. So far, several types of stem cells have been identified to be promising candidates to be applied for treatment: cardiac progenitor cells, bone marrow derived stem cells, embryonic and induced pluripotent stem cells, as well as their descendants. Furthermore, the innovative techniques of direct cardiac reprogramming of cells offered promising options for cardiovascular research, in vitro and in vivo. Hereby, the investigation of underlying and associated mechanisms triggering the therapeutic effects of stem cell application is of particular importance to improve approaches for heart patients. This Special Issue of Cells provides the latest update in the rapidly developing field of regenerative medicine in cardiology.

📒Stem Cells ✍ Mary Clarke

Stem Cells Book PDF
✏Book Title : Stem Cells
✏Author : Mary Clarke
✏Publisher : Garland Science
✏Release Date : 2020-07-27
✏Pages : 450
✏ISBN : 9781000062656
✏Available Language : English, Spanish, And French

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✏Stem Cells Book Summary : Stem cell science, encompassing basic biology to practical application, is both vast and diverse. A full appreciation of it requires an understanding of cell and molecular biology, tissue structure and physiology, the practicalities of tissue engineering and bioprocessing, and the pathways to clinical implementation—including the ethical and regulatory imperatives that our society requires us to address. Expectation and debate have been driven by the allure of regenerative medicine using stem cells as a source of replacements for damaged or aged tissues. The potential of stem cell application goes far beyond this. Highly innovative uses of stem cells are emerging as possible therapies for cancers, treating acute damage in conditions such as stroke and myocardial infarction, and resolving a whole range of diseases. Stem Cells: Biology and Application presents the basic concepts underlying the fast-moving science of stem cell biology. This textbook is written for an advanced stem cell biology course. The target audience includes senior undergraduates, first year graduate students, and practitioners in molecular biology, biology, and biomedical engineering. Stem Cells provides a comprehensive understanding of these unique cells, highlighting key areas of research, associated controversies, case studies, technologies, and pioneers in the field.

📒Adult And Pluripotent Stem Cells ✍ Jürgen Hescheler

Adult And Pluripotent Stem Cells Book PDF
✏Book Title : Adult and Pluripotent Stem Cells
✏Author : Jürgen Hescheler
✏Publisher : Springer Science & Business
✏Release Date : 2014-04-21
✏Pages : 170
✏ISBN : 9789401786577
✏Available Language : English, Spanish, And French

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✏Adult and Pluripotent Stem Cells Book Summary : There is hardly an area of research developing so quickly and raising so many promises as stem cell research. Adult, embryonic and recently available induced pluripotent stem cells not only foster our understanding of differentiation of endo-, ecto- and mesodermal lineages to all organs of the body, but foremost nourish the hope that cells grown in culture can be used for regeneration of diseased organs such as the heart damaged by myocardial infarction. This book focuses on perspectives of stem cells for regenerative therapy of cardiovascular diseases. Based on the EC consortium INELPY, it reviews the field and disseminates major outcomes of this project. Thus it introduces the reader to this fascinating area of research and incorporates very recent findings interesting to the expert, spanning the field from bench to bedside. The compilation of contributions is unique as there is yet no similar comprehensive overview combining stem cell research with preclinical and clinical evaluation as well as engineering of tissue patches for transplantation. As such it will be an invaluable source of information for all researchers in the stem cell and tissue regeneration field including bioengineers as well as for all clinicians interested in regenerative therapies, especially for ischemic cardiomyopathies.

Stem Cells From Basic Research To Therapy Volume Two Book PDF
✏Book Title : Stem Cells From Basic Research to Therapy Volume Two
✏Author : Federico Calegari
✏Publisher : CRC Press
✏Release Date : 2014-06-03
✏Pages : 474
✏ISBN : 9781482219838
✏Available Language : English, Spanish, And French

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✏Stem Cells From Basic Research to Therapy Volume Two Book Summary : The second volume in the Stem Cells series concentrates on the mechanisms of stem cell regeneration in the adult organism with a view towards understanding how lost tissue can be replaced during adulthood and aging. The second focus of this volume is on stem cell identification and manipulation, including applications in basic research, medicine, and industry. The book closes with an outlook on generalized approaches that can be used to solve legislative and ethical challenges.

Stem Cell And Biologic Scaffold Engineering Book PDF
✏Book Title : Stem Cell and Biologic Scaffold Engineering
✏Author : Panagiotis Mallis
✏Publisher : MDPI
✏Release Date : 2019-10-04
✏Pages : 110
✏ISBN : 9783039214976
✏Available Language : English, Spanish, And French

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✏Stem Cell and Biologic Scaffold Engineering Book Summary : Tissue engineering and regenerative medicine is a rapidly evolving research field which effectively combines stem cells and biologic scaffolds in order to replace damaged tissues. Biologic scaffolds can be produced through the removal of resident cellular populations using several tissue engineering approaches, such as the decellularization method. Indeed, the decellularization method aims to develop a cell-free biologic scaffold while keeping the extracellular matrix (ECM) intact. Furthermore, biologic scaffolds have been investigated for their in vitro potential for whole organ development. Currently, clinical products composed of decellularized matrices, such as pericardium, urinary bladder, small intestine, heart valves, nerve conduits, trachea, and vessels, are being evaluated for use in human clinical trials. Tissue engineering strategies require the interaction of biologic scaffolds with cellular populations. Among them, stem cells are characterized by unlimited cell division, self-renewal, and differentiation potential, distinguishing themselves as a frontline source for the repopulation of decellularized matrices and scaffolds. Under this scheme, stem cells can be isolated from patients, expanded under good manufacturing practices (GMPs), used for the repopulation of biologic scaffolds and, finally, returned to the patient. The interaction between scaffolds and stem cells is thought to be crucial for their infiltration, adhesion, and differentiation into specific cell types. In addition, biomedical devices such as bioreactors contribute to the uniform repopulation of scaffolds. Until now, remarkable efforts have been made by the scientific society in order to establish the proper repopulation conditions of decellularized matrices and scaffolds. However, parameters such as stem cell number, in vitro cultivation conditions, and specific growth media composition need further evaluation. The ultimate goal is the development of “artificial” tissues similar to native ones, which is achieved by properly combining stem cells and biologic scaffolds and thus bringing them one step closer to personalized medicine. The original research articles and comprehensive reviews in this Special Issue deal with the use of stem cells and biologic scaffolds that utilize state-of-the-art tissue engineering and regenerative medicine approaches.

Handbook Of Growth And Growth Monitoring In Health And Disease Book PDF
✏Book Title : Handbook of Growth and Growth Monitoring in Health and Disease
✏Author : Victor R. Preedy
✏Publisher : Springer Science & Business Media
✏Release Date : 2011-12-02
✏Pages : 3164
✏ISBN : 9781441917942
✏Available Language : English, Spanish, And French

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✏Handbook of Growth and Growth Monitoring in Health and Disease Book Summary : Growth is one of the human body’s most intricate processes: each body part or region has its own unique growth patterns. Yet at the individual and population levels, growth patterns are sensitive to adverse conditions, genetic predispositions, and environmental changes. And despite the body’s capacity to compensate for these developmental setbacks, the effects may be far-reaching, even life-long. The Handbook of Growth and Growth Monitoring in Health and Disease brings this significant and complex field together in one comprehensive volume: impact of adverse variables on growth patterns; issues at different stages of prenatal development, childhood, and adolescence; aspects of catch-up growth, endocrine regulation, and sexual maturation; screening and assessment methods; and international perspectives. Tables and diagrams, applications to other areas of health and disease, and summary points help make the information easier to retain. Together, these 140 self-contained chapters in 15 sections [ok?] cover every area of human growth, including: Intrauterine growth retardation. Postnatal growth in normal and abnormal situations. Cells and growth of tissues. Sensory growth and development. Effects of disease on growth. Methods and standards for assessment of growth, and more. The Handbook of Growth and Growth Monitoring in Health and Disease is an invaluable addition to the reference libraries of a wide range of health professionals, among them health scientists, physicians, physiologists, nutritionists, dieticians, nurses, public health researchers, epidemiologists, exercise physiologists, and physical therapists. It is also useful to college-level students and faculty in the health disciplines, and to policymakers and health economists.

Heart Failure A Companion To Braunwald S Heart Disease E Book Book PDF
✏Book Title : Heart Failure A Companion to Braunwald s Heart Disease E book
✏Author : Douglas L. Mann
✏Publisher : Elsevier Health Sciences
✏Release Date : 2010-11-11
✏Pages : 928
✏ISBN : 9781437703634
✏Available Language : English, Spanish, And French

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✏Heart Failure A Companion to Braunwald s Heart Disease E book Book Summary : Dr. Douglas L. Mann, one of the foremost experts in the field, presents the 2nd Edition of Heart Failure: A Companion to Braunwald’s Heart Disease. This completely reworked edition covers the scientific and clinical guidance you need to effectively manage your patients and captures the dramatic advances made in the field over the last five years. Now in full color, this edition features eleven new chapters, including advanced cardiac imaging techniques, use of biomarkers, cell-based therapies and tissue engineering, device therapies, and much more. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Compatible with Kindle®, nook®, and other popular devices. Use this Braunwald’s companion as the definitive source to prepare for the ABIM’s new Heart Failure board exam. Access the fully searchable contents of the book online at Expert Consult. This edition includes 67 new authors, who are experts in the field of heart failure Stay on the cutting edge with new chapters on: The latest practice guidelines for medical and device therapy Hemodynamic assessment of heart failure Contemporary medical therapy for heart failure patients with reduced and preserved ejection fraction Biomarkers in heart failure Pulmonary hypertension Management of co-morbidities in heart failure Mechanical cardiac support devices Get up to speed with the latest clinical trials, as well as how they have influenced current practice guidelines Explore what’s changing in key areas such as basic mechanisms of heart failure, genetic screening, cell and gene therapies, pulmonary hypertension, heart failure prevention, co-morbid conditions, telemedicine/remote monitoring, and palliative care

📒Stem Cell Transplantation ✍ Carlos López-Larrea

Stem Cell Transplantation Book PDF
✏Book Title : Stem Cell Transplantation
✏Author : Carlos López-Larrea
✏Publisher : Springer Science & Business Media
✏Release Date : 2012-03-28
✏Pages : 342
✏ISBN : 9781461420989
✏Available Language : English, Spanish, And French

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✏Stem Cell Transplantation Book Summary : Organ transplantation has been the most important therapeutic advance in the last third of the 20th century. Its development has revolutionized medicine, as demonstrated by the fact that a large number of researchers in this field have been awarded Nobel Prizes. In the beginning of this century, we are witnessing with great expectations the emergence of a new field of medicine related to the arrival of a new player on the scene: “stem cells” and their potential use in regenerative medicine. This volume aims to cover important aspects of the various facets of organ transplantation and regenerative medicine, with leading specialists in these fields setting out their vision. We try to rigorously explain current and novel scientific research in these fields—areas which arouse great interest from society in general, due to their potential use in modern medicine for the treatment of a great number of diseases.

📒Handbook Of Stem Cells ✍ Anthony Atala

Handbook Of Stem Cells Book PDF
✏Book Title : Handbook of Stem Cells
✏Author : Anthony Atala
✏Publisher : Academic Press
✏Release Date : 2012-12-31
✏Pages : 1074
✏ISBN : 9780123859433
✏Available Language : English, Spanish, And French

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✏Handbook of Stem Cells Book Summary : New discoveries in the field of stem cells increasingly dominate the news and scientific literature revealing an avalanche of new knowledge and research tools that are producing therapies for cancer, heart disease, diabetes, and a wide variety of other diseases that afflict humanity. The Handbook of Stem Cells integrates this exciting area of life science, combining in two volumes the requisites for a general understanding of adult and embryonic stem cells. Organized in two volumes entitled Pluripotent Stem Cells and Cell Biology and Adult and Fetal Stem Cells, this work contains contributions from the world’s experts in stem cell research to provide a description of the tools, methods, and experimental protocols needed to study and characterize stem cells and progenitor populations as well as a the latest information of what is known about each specific organ system. Provides comprehensive coverage on this highly topical subject Contains contributions by the foremost authorities and premiere names in the field of stem cell research Companion website - - contains over 250 color figures in presentation format

📒Stem Cell And Gene Based Therapy ✍ Alexander Battler

Stem Cell And Gene Based Therapy Book PDF
✏Book Title : Stem Cell and Gene Based Therapy
✏Author : Alexander Battler
✏Publisher : Springer Science & Business Media
✏Release Date : 2007-06-26
✏Pages : 422
✏ISBN : 184628676X
✏Available Language : English, Spanish, And French

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✏Stem Cell and Gene Based Therapy Book Summary : Regenerative medicine – stem cell and gene-based therapy – offers a new approach for restoring function of damaged organs and tissues. This is the first book to cover the major new aspects and field of regenerative medicine. This title is therefore a timely addition to the literature. It brings together the major approaches to regenerative medicine in one text, which ensures that techniques learnt in one discipline are disseminated across other areas of medicine.

Emerging Trends In Cell And Gene Therapy Book PDF
✏Book Title : Emerging Trends in Cell and Gene Therapy
✏Author : Michael K. Danquah
✏Publisher : Springer Science & Business Media
✏Release Date : 2013-06-14
✏Pages : 705
✏ISBN : 9781627034173
✏Available Language : English, Spanish, And French

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✏Emerging Trends in Cell and Gene Therapy Book Summary : Examples from various organs and diseases illustrate the potential benefit obtained when both therapeutic approaches are combined with delivery strategies. Representing the combined effort of several leading international research and clinical experts, this book, Emerging Trends in Cell and Gene Therapy, provides a complete account on and brings into sharp focus current trends and state-of-the-art in important areas at the interface of cell- and gene-based therapies. This book addresses the current fragmented understanding regarding these two research areas and fills the vast unmet educational need and interest of both students and researchers in academia and industry. Main features of the book: · Biological aspects of stem cell sources, differentiation and engineering. · Application of microfluidics to study stem cell dynamics · Potential clinical application of stem cells and gene therapy to specific human disease. · Utilization of biomaterials and stem cells in regenerative medicine with particular emphasis on spinal cord repair, ligament and bone tissue engineering. · Biomimetic multiscale topography for cell alignment.

Progress In Stem Cell Applications Book PDF
✏Book Title : Progress in Stem Cell Applications
✏Author : Allen V. Faraday
✏Publisher : Nova Publishers
✏Release Date : 2008
✏Pages : 435
✏ISBN : 1604563168
✏Available Language : English, Spanish, And French

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✏Progress in Stem Cell Applications Book Summary : This book is devoted to recent research in stem cell applications. Stem cells are the foundation cells for every organ, tissue and cell in the body. They are like a blank microchip that can ultimately be programmed to perform any number of specialised tasks. Stem cells are undifferentiated, "blank" cells that do not yet have a specific function. Under proper conditions, stem cells begin to develop into specialised tissues and organs. Additionally, stem cells are self-sustaining and can replicate themselves for long periods of time. These unique characteristics make stem cells very promising for supplying cells to treat debilitating diseases like Alzheimer's disease, cancer, Parkinson's disease, type-1 diabetes, spinal cord injury, stroke, burns, heart disease, osteoarthritis and rheumatoid arthritis.

Heart Development Book PDF
✏Book Title : Heart Development
✏Author :
✏Publisher : Academic Press
✏Release Date : 2012-05-10
✏Pages : 408
✏ISBN : 9780123877901
✏Available Language : English, Spanish, And French

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✏Heart Development Book Summary : The developing heart is the first functional organ, and its proper formation and function is essential for life. This volume compiles the exciting new advances that have been made in understanding the regulation of heart development, the genes and pathways involved, and the impact these have in heart disease. A stellar collection of scientists tackles an important facet of heart development, providing a comprehensive set of reviews. Cutting-edge science Authority of contributors Exciting field of research

An Essential Guide To Cardiac Cell Therapy Book PDF
✏Book Title : An Essential Guide to Cardiac Cell Therapy
✏Author : Emerson Perin
✏Publisher : CRC Press
✏Release Date : 2006-09-15
✏Pages : 208
✏ISBN : 1841844713
✏Available Language : English, Spanish, And French

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✏An Essential Guide to Cardiac Cell Therapy Book Summary : Sparked by a new understanding that the development of tissues is not restricted to the embryonic phase of development and thus that regeneration of tissues can occur in adults, the emerging field of stem cell therapy has grown exponentially in the last several years. Crucially, the research and findings associated with stem cell research overlap into many other areas, such as basic cell biology, molecular biology and hematology, and the proliferation of clinical studies involving stem cell research is gradually crossing over into the practice of medicine as many patients may become candidates for such novel treatments. As a response to this, Guide to Cardiac Cell Therapy is a comprehensive but understandable resource that makes this exciting field accessible to clinical practitioners. Bridging the gap between basic science and practice, it is a useful introduction to the area as well as a cutting-edge update of the developments in stem cell therapy as applied to cardiovascular disease.