Recent Advances In Ipsc Disease Modeling Volume 1

Recent Advances In Ipsc Disease Modeling Volume 1 Book PDF
✏Book Title : Recent Advances in iPSC Disease Modeling Volume 1
✏Author : ALEXANDER BIRBRAIR
✏Publisher : Academic Press
✏Release Date : 2020-07-16
✏Pages : 320
✏ISBN : 9780128232699
✏Available Language : English, Spanish, And French

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✏Recent Advances in iPSC Disease Modeling Volume 1 Book Summary : Recent Advances in iPSC Disease Modeling, Volume 1 addresses how induced pluripotent stem cells can be used to model various diseases. Somatic cells are reprogrammed into induced pluripotent stem cells by the expression of specific transcription factors. These cells are transforming biomedical research in the last 15 years. This volume teaches readers about current advances in the field. This book describes the use of induced pluripotent stem cells to model several diseases in vitro, enabling us to study the cellular and molecular mechanisms involved in different pathologies. Further insights into these mechanisms will have important implications for our understanding of disease appearance, development, and progression. In recent years, remarkable progress has been made in the obtention of induced pluripotent stem cells and their differentiation into several cell types, tissues, and organs using state-of-art techniques. These advantages facilitated identification of key targets and definition of the molecular basis of several disorders. The volume is written for researchers and scientists in stem cell therapy, cell biology, regenerative medicine and organ transplantation; and is contributed by world-renowned authors in the field. Provides overview of the fast-moving field of induced pluripotent stem cell technology, regenerative medicine, and therapeutics Covers the following diseases: severe congenital neutropenia, sickle cell and Diamond-Blackfan anemias, muscular dystrophies, Bernard-Soulier syndrome, familial hypercholesterolemia type II A, Werner syndrome, lysosomal storage diseases, and more Contains description of cutting-edge research on the development of disease-specific human pluripotent stem cells. These cells allow us to study cellular and molecular processes involved in several human diseases

Stem Cells And Cancer Stem Cells Volume 10 Book PDF
✏Book Title : Stem Cells and Cancer Stem Cells Volume 10
✏Author : M.A. Hayat
✏Publisher : Springer Science & Business Media
✏Release Date : 2013-03-20
✏Pages : 298
✏ISBN : 9789400762626
✏Available Language : English, Spanish, And French

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✏Stem Cells and Cancer Stem Cells Volume 10 Book Summary : Presenting contributions by 66 experts representing 13 countries, Volume 10 of the series Stem Cells and Cancer Stem Cells synthesizes current understanding of the causes, diagnosis, and therapy of major human diseases and debilitating tissue and organ injuries, using cell-based treatment. This volume presents contemporary research into generation, preservation, and uses of stem cells in fighting disease and tissue/organ injuries. The contents of the volume are organized into five sections. Mesenchymal Stem Cells section includes chapters on the use of stem cells in bone regeneration, studies and trials of stem cells in autoimmune diseases, and differences between adipose tissue-derived mesenchymal stem cells and bone marrow-derived mesenchymal stem cells as regulators of immune response. Induced Pluripotent Stem Cells section offers chapters on drug discovery using human IPSC-based disease models, and on generation of antigen-specific lymphocytes from IPSCs. Neural Cells and Neural Stem Cells section discusses use of bacterial artificial chromosomes in the genetic identification of stem cell-derived neural cell types, and use of moderate low temperature to preserve the stemness of neural stem cells. The section, Role of Stem Cells in Disease, discusses stem cell support in high-dose chemotherapy of Non-Hodgkin’s Lymphomas; potential targets for drug resistant leukemic stem cells, bone marrow stem cell therapies for diabetes mellitus. This section also discusses the use of stem cells in treating thyroid, breast and bone cancers, hempophilia and Parkinson’s Disease. The section, Stem Cell Transplantation, includes chapters on reducing fungal infection in allogenic stem cell transplantation patients, use of Bulsufan/Fludarabine for conditioning in haematopoietic stem cell transplantation, and interleukin-7 receptor alpha polymorphisms in allogeneic stem cell transplantation. The editor, M.A. Hayat, is a Distinguished Professor in the Department of Biological, Sciences at Kean University, Union, New Jersey, USA.

Recent Advances In Parkinson S Disease Book PDF
✏Book Title : Recent Advances in Parkinson s Disease
✏Author :
✏Publisher : Academic Press
✏Release Date : 2020-04-02
✏Pages : 574
✏ISBN : 9780444642615
✏Available Language : English, Spanish, And French

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✏Recent Advances in Parkinson s Disease Book Summary : Recent Advances in Parkinson ́s Disease Research, Volume 252, represents a follow-up on two previous volumes presented in the Progress in Brain Research series, Volumes 193 and 193, both published in 2010. It contains a collection of overview articles written by leading researchers in Parkinson's, discussing the most important advances made in basic, translational and clinical research. Topics of note in this new release include What can we learn from iPS cell models of PD, What can we learn from animal models of PD?, Molecular basis of selective neuronal vulnerability in PD, Role of innate and adaptive immunity in Parkinson ́s disease, and much more. Covers all key aspects of current research on Parkinson ́s disease Includes topics that range from basic studies on disease models and pathogenic pathways (e.g., protein misfolding, immune and glial mechanisms) to clinical studies on disease features, microbiome, pathophysiology and therapeutic approaches Presents articles authored by world leaders in their respective fields

Cell Biology And Translational Medicine Volume 1 Book PDF
✏Book Title : Cell Biology and Translational Medicine Volume 1
✏Author : Kursad Turksen
✏Publisher : Springer
✏Release Date : 2018-08-21
✏Pages : 168
✏ISBN : 9783319938677
✏Available Language : English, Spanish, And French

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✏Cell Biology and Translational Medicine Volume 1 Book Summary : Much research has focused on the basic cellular and molecular biological aspects of stem cells. Much of this research has been fueled by their potential for use in regenerative medicine applications, which has in turn spurred growing numbers of translational and clinical studies. However, more work is needed if the potential is to be realized for improvement of the lives and well-being of patients with numerous diseases and conditions. With a goal to accelerate advances by timely information exchange, this new book series 'Cell Biology and Translational Medicine (CBTMED)' as part of SpringerNature’s longstanding and very successful Advances in Experimental Medicine and Biology book series is launched. Emerging areas of regenerative medicine and translational aspects of stem cells will be covered in each volume. Outstanding researchers are recruited to highlight developments and remaining challenges in both the basic research and clinical arenas. This current book is the first volume of a continuing series.

Ipscs For Modeling Central Nervous System Disorders Volume 6 Book PDF
✏Book Title : iPSCs for Modeling Central Nervous System Disorders Volume 6
✏Author : Alexander Birbrair
✏Publisher : Academic Press
✏Release Date : 2021-05-01
✏Pages : 300
✏ISBN : 9780323856423
✏Available Language : English, Spanish, And French

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✏iPSCs for Modeling Central Nervous System Disorders Volume 6 Book Summary : The series Advances in Stem Cell Biology is a timely and expansive collection of comprehensive information and new discoveries in the field of stem cell biology. iPSC Central Nervous System Disease Modeling, Volume 13 addresses how important induced pluripotent stems cells are and how they can be used to model CNS disorders. The creation of iPSC technology allowed the development of disease-specific human pluripotent stem cells. These cells allow researchers to study questions impossible before for some human diseases. This volume addresses central nervous system disease modeling, such as: Leber’s hereditary optic neuropathy, autism, spinal muscular atrophy, Alzheimer’s disease, ALS and much more. The volume is written for researchers and scientists in stem cell therapy, cell biology, regenerative medicine and organ transplantation; and is contributed by world-renowned authors in the field. Provides overview of the fast-moving field of stem cell biology and function, regenerative medicine and therapeutics Covers how iPSCs can be used to model CNS disorders Contributed by world-renown experts in the field

Cell Biology And Translational Medicine Volume 7 Book PDF
✏Book Title : Cell Biology and Translational Medicine Volume 7
✏Author : Kursad Turksen
✏Publisher : Springer Nature
✏Release Date : 2020-02-03
✏Pages : 153
✏ISBN : 9783030378455
✏Available Language : English, Spanish, And French

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✏Cell Biology and Translational Medicine Volume 7 Book Summary : Much research has focused on the basic cellular and molecular biological aspects of stem cells. Much of this research has been fueled by their potential for use in regenerative medicine applications, which has in turn spurred growing numbers of translational and clinical studies. However, more work is needed if the potential is to be realized for improvement of the lives and well-being of patients with numerous diseases and conditions. This book series 'Cell Biology and Translational Medicine (CBTMED)' as part of SpringerNature’s longstanding and very successful Advances in Experimental Medicine and Biology book series, has the goal to accelerate advances by timely information exchange. Emerging areas of regenerative medicine and translational aspects of stem cells are covered in each volume. Outstanding researchers are recruited to highlight developments and remaining challenges in both the basic research and clinical arenas. This current book is the seventh volume of a continuing series.

Lung Stem Cells In The Epithelium And Vasculature Book PDF
✏Book Title : Lung Stem Cells in the Epithelium and Vasculature
✏Author : Amy Firth
✏Publisher : Springer
✏Release Date : 2015-05-23
✏Pages : 345
✏ISBN : 9783319162324
✏Available Language : English, Spanish, And French

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✏Lung Stem Cells in the Epithelium and Vasculature Book Summary : This book covers the identification and role of endogenous lung stem cells in health and disease, particularly the most recent advances. In addition, it discusses the rapidly growing field of stem cells and cell therapy as it relates to lung biology and disease as well as ex vivo lung bioengineering. Such approaches may provide novel therapeutic approaches for lung diseases. Human pluripotent stem cell differentiation to model the pulmonary epithelium and vasculature is also discussed. World-recognized scientists who specialize in studying both the lung epithelium and pulmonary vasculature contribute the chapters. Topics covered include: stem cell niches in the lung, the role of progenitor cells in fibrosis and asthma, iPSC in modeling lung disease, vascular repair by endothelial progenitor cells and circulating fibrocytes in pulmonary vascular remodeling. This volume of the Stem Cell Biology and Regenerative Medicine series is essential reading for researchers and clinicians interested in stem cells, lung biology and regenerative medicine. It is also an invaluable resource for advanced students studying cell biology, regenerative medicine and lung physiology.

📒Neural Stem Cell Assays ✍ Navjot Kaur

Neural Stem Cell Assays Book PDF
✏Book Title : Neural Stem Cell Assays
✏Author : Navjot Kaur
✏Publisher : John Wiley & Sons
✏Release Date : 2014-11-24
✏Pages : 288
✏ISBN : 9781118308271
✏Available Language : English, Spanish, And French

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✏Neural Stem Cell Assays Book Summary : Neural stem cells offer a valuable model system for delineating the cellular and developmental processes in normal and diseased states of the central nervous system. In particular, neural stem cells have huge potential in regenerative medicine, owing to their expansion capability in culture and the ability to differentiate into multiple sub-neural lineages. Neural Stem Cell Assays provides a detailed and comprehensive review of the basic methods for neural stem cell cultures. Including an overview of progress in the field over the past decade, Neural Stem Cell Assays is a one-stop reference for consistent methods and reliable tools that span the entire assay work flow, from isolation or generation of neural stem cells to characterization, manipulation and final application of neural stem cells in disease paradigms such as Parkinson's disease, multiple sclerosis and amyotrophic lateral sclerosis. An excellent source of information for academic, pharmaceutical and biotechnology researchers who are new to the neural stem cell field, Neural Stem Cell Assays is an invaluable to experienced users who wish to integrate newly developed tools and technologies into their workflow. The book also covers important course material for students at the undergraduate and graduate level who are learning the basics of neural stem cell cultures, and differentiation to sub-neural lineages.

📒Ipscs From Diverse Species ✍ ALEXANDER BIRBRAIR

Ipscs From Diverse Species Book PDF
✏Book Title : iPSCs from Diverse Species
✏Author : ALEXANDER BIRBRAIR
✏Publisher : Academic Press
✏Release Date : 2020-10-12
✏Pages : 272
✏ISBN : 9780323851855
✏Available Language : English, Spanish, And French

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✏iPSCs from Diverse Species Book Summary : The series Advances in Stem Cell Biology is a timely and expansive collection of comprehensive information and new discoveries in the field of stem cell biology. iPSCs from Diverse Species, Volume 2 addresses how induced pluripotent stem cells (iPSCs) can be derived from different species. The volume teaches the reader about modern state-of-the-art methodologies to derive iPSCs from distinct species. This volume will cover how to derive iPSCs from species like nonhuman primates, horses, dogs, pigs, rats, rabbits, and others. It also discusses the importance of iPSCs in species conservation. Detailed description on methods used to obtain iPSCs from humans and other species expands the knowledge and understanding of stem cell biology and provides a potent tool to model diseases. The volume is written for researchers and scientists in stem cell biology, and regenerative medicine and is contributed by world-renowned authors in the field. Provides overview of the fast-moving field of stem cell biology and function, regenerative medicine and therapeutics Covers the following signaling pathways: notch, hedgehog, TGFβ, PAR2 and more Contributions from stem cell leaders around the world

Cardiovascular Regenerative Medicine Book PDF
✏Book Title : Cardiovascular Regenerative Medicine
✏Author : Vahid Serpooshan
✏Publisher : Springer
✏Release Date : 2019-06-29
✏Pages : 233
✏ISBN : 9783030200473
✏Available Language : English, Spanish, And French

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✏Cardiovascular Regenerative Medicine Book Summary : This book is a comprehensive and up-to-date resource on the use of regenerative medicine for the treatment of cardiovascular disease. It provides a much-needed review of the rapid development and evolution of bio-fabrication techniques to engineer cardiovascular tissues as well as their use in clinical settings. The book incorporates recent advances in the biology, biomaterial design, and manufacturing of bioengineered cardiovascular tissue with their clinical applications to bridge the basic sciences to current and future cardiovascular treatment. The book begins with an examination of state-of-the-art cellular, biomaterial, and macromolecular technologies for the repair and regeneration of diseased heart tissue. It discusses advances in nanotechnology and bioengineering of cardiac microtissues using acoustic assembly. Subsequent chapters explore the clinical applications and translational potential of current technologies such as cardiac patch-based treatments, cell-based regenerative therapies, and injectable hydrogels. The book examines how these methodologies are used to treat a variety of cardiovascular diseases including myocardial infarction, congenital heart disease, and ischemic heart injuries. Finally, the volume concludes with a summary of the most prominent challenges and perspectives on the field of cardiovascular tissue engineering and clinical cardiovascular regenerative medicine. Cardiovascular Regenerative Medicine is an essential resource for physicians, residents, fellows, and medical students in cardiology and cardiovascular regeneration as well as clinical and basic researchers in bioengineering, nanomaterial and technology, and cardiovascular biology.

Advances In Research On Neurodegeneration Book PDF
✏Book Title : Advances in Research on Neurodegeneration
✏Author : P. Riederer
✏Publisher : Springer
✏Release Date : 1997-01-24
✏Pages : 216
✏ISBN : 3211829334
✏Available Language : English, Spanish, And French

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✏Advances in Research on Neurodegeneration Book Summary : Volume 5 of the series "Advances in Research on Neurodegeneration" is concerned with themes which are currently the focus of intensive research, and in which advances in our understanding of the pathological mechanisms un derlying neurodegenerative diseases are expected in the near future. The first section contains five reviews devoted to the various neuroimaging technolo gies. The discussion is concerned with the question of whether neuroimaging techniques make it possible to follow the process of degeneration as it occurs, and which methods offer the required sensitivity and quantifiability for this purpose. However, the question needs to be examined of whether, given the physical and chemical limitations of these techniques, even under optimal conditions, anatomical resolution can be improved to the extent that neuro degenerative diseases can be diagnosed earlier than currently possible and a confident diagnosis made. The possibilities of using neuroimaging techniques to provide information regarding the effects of neuroprotective or neuroregen erative therapeutic strategies, and for correlating the results of neuropsycho logical research with imaging data are also discussed. The second section is concerned with the significance of endogenous or exogenous neurotoxins as triggers for neurodegenerative processes that may lead to Parkinsonism. Vulnerability factors, which include such factors as nerve ending sensitivity, the synergistic effects of drugs and the various mechanisms underlying different toxins are discussed.

Rna Metabolism In Neurodegenerative Diseases Book PDF
✏Book Title : RNA Metabolism in Neurodegenerative Diseases
✏Author : Rita Sattler
✏Publisher : Springer
✏Release Date : 2018-06-18
✏Pages : 310
✏ISBN : 9783319896892
✏Available Language : English, Spanish, And French

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✏RNA Metabolism in Neurodegenerative Diseases Book Summary : It has become evident over the last years that abnormalities in RNA processing play a fundamental part in the pathogenesis of neurodegenerative diseases. Cellular viability depends on proper regulation of RNA metabolism and subsequent protein synthesis, which requires the interplay of many processes including transcription, pre--‐mRNA splicing, mRNA editing as well as mRNA stability, transport and translation. Dysfunction in any of these processes, often caused by mutations in the coding and non--‐ coding RNAs, can be very destructive to the cellular environment and consequently impair neural viability. The result of this RNA toxicity can lead to a toxic gain of function or a loss of function, depending on the nature of the mutation. For example, in repeat expansion disorders, such as the newly discovered hexanucleotide repeat expansion in theC9orf72 gene found in amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), a toxic gain of function leads to the formation of RNA foci and the sequestration of RNA binding proteins (RBPs). This in return leads to a loss of function of those RBPs, which is hypothesized to play a significant part in the disease progression of ALS and FTD. Other toxicities arising from repeat expansions are the formation of RNA foci, bi--‐directional transcription and production of repeat associated non--‐ATG (RAN) translation products. This book will touch upon most of these disease mechanisms triggered by aberrant RNA metabolism and will therefore provide a broad perspective of the role of RNA processing and its dysfunction in a variety of neurodegenerative disorders, including ALS, FTD, Alzheimer’s disease, Huntington’s disease, spinal muscular atrophy, myotonic dystrophy and ataxias. The proposed authors are leading scientists in the field and are expected to not only discuss their own work, but to be inclusive of historic as well as late breaking discoveries. The compiled chapters will therefore provide a unique collection of novel studies and hypotheses aimed to describe the consequences of altered RNA processing events and its newest molecular players and pathways.

Issues In General Science And Scientific Theory And Method 2011 Edition Book PDF
✏Book Title : Issues in General Science and Scientific Theory and Method 2011 Edition
✏Author :
✏Publisher : ScholarlyEditions
✏Release Date : 2012-01-09
✏Pages : 3278
✏ISBN : 9781464963476
✏Available Language : English, Spanish, And French

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✏Issues in General Science and Scientific Theory and Method 2011 Edition Book Summary : Issues in General Science and Scientific Theory and Method: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about General Science and Scientific Theory and Method. The editors have built Issues in General Science and Scientific Theory and Method: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about General Science and Scientific Theory and Method in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in General Science and Scientific Theory and Method: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Index To Theses With Abstracts Accepted For Higher Degrees By The Universities Of Great Britain And Ireland And The Council For National Academic Awards Book PDF
✏Book Title : Index to Theses with Abstracts Accepted for Higher Degrees by the Universities of Great Britain and Ireland and the Council for National Academic Awards
✏Author :
✏Publisher :
✏Release Date : 2004
✏Pages :
✏ISBN : STANFORD:36105115071487
✏Available Language : English, Spanish, And French

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✏Index to Theses with Abstracts Accepted for Higher Degrees by the Universities of Great Britain and Ireland and the Council for National Academic Awards Book Summary : Theses on any subject submitted by the academic libraries in the UK and Ireland.

📒Society For Neuroscience Abstracts ✍ Society for Neuroscience. Meeting

Society For Neuroscience Abstracts Book PDF
✏Book Title : Society for Neuroscience Abstracts
✏Author : Society for Neuroscience. Meeting
✏Publisher :
✏Release Date : 2000
✏Pages :
✏ISBN : NWU:35557000123362
✏Available Language : English, Spanish, And French

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✏Society for Neuroscience Abstracts Book Summary :