Real World Drug Discovery

Produk Detail:
  • Author : Robert M. Rydzewski
  • Publisher : Elsevier
  • Pages : 600 pages
  • ISBN : 9780080914886
  • Rating : 5/5 from 1 reviews
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Download or Read online Real World Drug Discovery full in PDF, ePub and kindle. this book written by Robert M. Rydzewski and published by Elsevier which was released on 07 July 2010 with total page 600 pages. We cannot guarantee that Real World Drug Discovery book is available in the library, click Get Book button and read full online book in your kindle, tablet, IPAD, PC or mobile whenever and wherever You Like. Drug discovery increasingly requires a common understanding by researchers of the many and diverse factors that go into the making of new medicines. The scientist entering the field will immediately face important issues for which his education may not have prepared him: project teams, patent law, consultants, target product profiles, industry trends, Gantt charts, target validation, pharmacokinetics, proteomics, phenotype assays, biomarkers, and many other unfamiliar topics for which a basic understanding must somehow be obtained. Even the more experienced scientist can find it frustratingly difficult to get an overview of the many factors involved in modern drug discovery and often only after years of exploring does a whole and integrated picture emerge in the mind of the researcher. Real World Drug Discovery: A Chemist’s Guide to Biotech and Pharmaceutical Research presents this kind of map of the landscape of drug discovery. In a single, readable volume it outlines processes and explains essential concepts and terms for the recent science graduate wondering what to expect in pharma or biotech, the medicinal chemist seeking a broader and more timely understanding of the industry, or the contractor or collaborator whose understanding of the commercial drug discovery process could increase the value of his contribution to it. Interviews with well-known experts in many of the fields involved, giving insightful comments from authorities on many of the sub-disciplines important to cutting edge drug discovery. Helpful suggestions gleaned from years of experience in biotech and pharma, which represents a repository drug discovery "lore" not previously available in any book. "Periodic Table of Drugs" listing current top-selling drugs arranged by target and laid out so that structural similarities and differences are plain and clear. Extensive use of diagrams to illustrate concepts like biotech startup models, preteomic profiling for target identification, Gantt charts for project planning, etc.

Real World Drug Discovery

Real World Drug Discovery
  • Author : Robert M. Rydzewski
  • Publisher : Elsevier
  • Release : 07 July 2010
GET THIS BOOK Real World Drug Discovery

Drug discovery increasingly requires a common understanding by researchers of the many and diverse factors that go into the making of new medicines. The scientist entering the field will immediately face important issues for which his education may not have prepared him: project teams, patent law, consultants, target product profiles, industry trends, Gantt charts, target validation, pharmacokinetics, proteomics, phenotype assays, biomarkers, and many other unfamiliar topics for which a basic understanding must somehow be obtained. Even the more experienced scientist

Real World Evidence in Drug Development and Evaluation

Real World Evidence in Drug Development and Evaluation
  • Author : YANG
  • Publisher : Chapman & Hall/CRC Biostatistics Series
  • Release : 16 February 2021
GET THIS BOOK Real World Evidence in Drug Development and Evaluation

Real-world evidence (RWE) has been at the forefront of pharmaceutical innovations. It plays an important role in transforming drug development from a process aimed at meeting regulatory expectations to an operating model that leverages data from disparate sources to aid business, regulatory, and healthcare decision making. Despite its many benefits, there is no single book systematically covering the latest development in the field. Written specifically for pharmaceutical practitioners, Real-World Evidence in Drug Development and Evaluation, presents a wide range of

Real World Evidence in Drug Development and Evaluation

Real World Evidence in Drug Development and Evaluation
  • Author : Harry Yang,Binbing Yu
  • Publisher : CRC Press
  • Release : 16 February 2021
GET THIS BOOK Real World Evidence in Drug Development and Evaluation

Real-world evidence (RWE) has been at the forefront of pharmaceutical innovations. It plays an important role in transforming drug development from a process aimed at meeting regulatory expectations to an operating model that leverages data from disparate sources to aid business, regulatory, and healthcare decision making. Despite its many benefits, there is no single book systematically covering the latest development in the field. Written specifically for pharmaceutical practitioners, Real-World Evidence in Drug Development and Evaluation, presents a wide range of

Drug Discovery and Development Volume 2

Drug Discovery and Development  Volume 2
  • Author : Mukund S. Chorghade
  • Publisher : John Wiley & Sons
  • Release : 16 February 2007
GET THIS BOOK Drug Discovery and Development Volume 2

From first principles to real-world applications-here is the first comprehensive guide to drug discovery and development Modern drug discovery and development require the collaborative efforts of specialists in a broadarray of scientific, technical, and business disciplines-from biochemistry to molecular biology, organic chemistry to medicinal chemistry, pharmacology to marketing. Yet surprisingly, until now, there were no authoritative references offering a complete, fully integrated picture of the process. The only comprehensive guide of its kind, this groundbreaking two-volume resource provides an overview

Drug Discovery and Development Volume 1

Drug Discovery and Development  Volume 1
  • Author : Mukund S. Chorghade
  • Publisher : John Wiley & Sons
  • Release : 18 July 2006
GET THIS BOOK Drug Discovery and Development Volume 1

This two volume set provides a comprehensive account of the entiresequence of operations involved in discovering a drug through theactual delivery of the drug to clinicians and medicalpractitioners. Includes case studies of the discovery of erythromycin analogs(antibiotics), Tagamet, and Ultiva (remifentanil) Discusses the discovery of agents for the treatment andmanagement of bacterial infections, Parkinson's disease, psoriasis,ulcers and stomach pain, atopic dermatitis, asthma, and cancer Contains chapters on combinatorial chemistry, molecularbiology-based drug discovery, genomics, and chemogenomics The first volume

Natural Products and Drug Discovery

Natural Products and Drug Discovery
  • Author : Subhash C. Mandal,Vivekananda Mandal,Tetsuya Konishi
  • Publisher : Elsevier
  • Release : 16 February 2018
GET THIS BOOK Natural Products and Drug Discovery

Natural Products and Drug Discovery: An Integrated Approach provides an applied overview of the field, from traditional medicinal targets, to cutting-edge molecular techniques. Natural products have always been of key importance to drug discovery, but as modern techniques and technologies have allowed researchers to identify, isolate, extract and synthesize their active compounds in new ways, they are once again coming to the forefront of drug discovery. Combining the potential of traditional medicine with the refinement of modern chemical technology, the

Molecular Pharmacology

Molecular Pharmacology
  • Author : John Dickenson,Fiona Freeman,Chris Lloyd Mills,Christian Thode,Shiva Sivasubramaniam
  • Publisher : John Wiley & Sons
  • Release : 30 November 2012
GET THIS BOOK Molecular Pharmacology

This textbook provides a fresh, comprehensive and accessible introduction to the rapidly expanding field of molecular pharmacology. Adopting a drug target-based, rather than the traditional organ/system based, approach this innovative guide reflects the current advances and research trend towards molecular based drug design, derived from a detailed understanding of chemical responses in the body. Drugs are then tailored to fit a treatment profile, rather than the traditional method of ‘trial and error’ drug discovery which focuses on testing chemicals

Drug Discovery and Development Volume 1

Drug Discovery and Development  Volume 1
  • Author : Mukund S. Chorghade
  • Publisher : Wiley-Interscience
  • Release : 16 June 2006
GET THIS BOOK Drug Discovery and Development Volume 1

This two volume set provides a comprehensive account of the entire sequence of operations involved in discovering a drug through the actual delivery of the drug to clinicians and medical practitioners. Includes case studies of the discovery of erythromycin analogs (antibiotics), Tagamet, and Ultiva (remifentanil) Discusses the discovery of agents for the treatment and management of bacterial infections, Parkinson's disease, psoriasis, ulcers and stomach pain, atopic dermatitis, asthma, and cancer Contains chapters on combinatorial chemistry, molecular biology-based drug discovery, genomics,

Collaborative Innovation in Drug Discovery

Collaborative Innovation in Drug Discovery
  • Author : Rathnam Chaguturu
  • Publisher : John Wiley & Sons
  • Release : 28 March 2014
GET THIS BOOK Collaborative Innovation in Drug Discovery

Can academia save the pharmaceutical industry? The pharmaceutical industry is at a crossroads. The urgent needfor novel therapies cannot stem the skyrocketing costs andplummeting productivity plaguing R&D, and many key products arefacing patent expiration. Dr. Rathnam Chaguturu presents a case forcollaboration between the pharmaceutical industry and academia thatcould reverse the industry's decline. CollaborativeInnovation in Drug Discovery: Strategies for Public and PrivatePartnerships provides insight into the potential synergyof basing R&D in academia while leaving drug companies to turnhits into

Integrated Strategies for Drug Discovery Using Mass Spectrometry

Integrated Strategies for Drug Discovery Using Mass Spectrometry
  • Author : Mike S. Lee
  • Publisher : John Wiley & Sons
  • Release : 02 September 2005
GET THIS BOOK Integrated Strategies for Drug Discovery Using Mass Spectrometry

New strategies and techniques for today's fast-paced discoveryprocess Today, the pressure is on for high-throughput approaches toaccelerate the generation, identification, and optimization ofmolecules with desirable drug properties. As traditional methods ofanalysis become antiquated, new analytical strategies andtechniques are necessary to meet sample throughput requirements andmanpower constraints. Among them, mass spectrometry has grown to bea front-line tool throughout drug discovery. Integrated Strategies for Drug Discovery Using Mass Spectrometryprovides a thorough review of current analytical approaches,industry practices, and strategies in drug

Bioisosteres in Medicinal Chemistry

Bioisosteres in Medicinal Chemistry
  • Author : Nathan Brown
  • Publisher : John Wiley & Sons
  • Release : 18 June 2012
GET THIS BOOK Bioisosteres in Medicinal Chemistry

Written with the practicing medicinal chemist in mind, this is the first modern handbook to systematically address the topic of bioisosterism. As such, it provides a ready reference on the principles and methods of bioisosteric replacement as a key tool in preclinical drug development. The first part provides an overview of bioisosterism, classical bioisosteres and typical molecular interactions that need to be considered, while the second part describes a number of molecular databases as sources of bioisosteric identification and rationalization.

Real World Evidence in Drug Development and Evaluation

Real World Evidence in Drug Development and Evaluation
  • Author : Harry Yang,Binbing Yu
  • Publisher : CRC Press
  • Release : 11 January 2021
GET THIS BOOK Real World Evidence in Drug Development and Evaluation

Real-world evidence (RWE) has been at the forefront of pharmaceutical innovations. It plays an important role in transforming drug development from a process aimed at meeting regulatory expectations to an operating model that leverages data from disparate sources to aid business, regulatory, and healthcare decision making. Despite its many benefits, there is no single book systematically covering the latest development in the field. Written specifically for pharmaceutical practitioners, Real-World Evidence in Drug Development and Evaluation, presents a wide range of

Antiviral Drugs

Antiviral Drugs
  • Author : Wieslaw M. Kazmierski
  • Publisher : John Wiley & Sons
  • Release : 08 July 2011
GET THIS BOOK Antiviral Drugs

This book focuses on new small molecule approaches to combat viral infections. The chapters describe the discovery and development from bench through the clinic of relatively recently-approved antiviral drugs and compounds in advanced clinical development. Organized by a virus (such as HIV, HCV, RSV, influenza, HBV and CMV) and written by top academic and industrial authorities in the field, the book provides a unique opportunity to study, understand and apply discovery and development principles and learning without the need for

In Silico Drug Discovery and Design

In Silico Drug Discovery and Design
  • Author : Claudio N. Cavasotto
  • Publisher : CRC Press
  • Release : 01 July 2017
GET THIS BOOK In Silico Drug Discovery and Design

In Silico Drug Discovery and Design: Theory, Methods, Challenges, and Applications provides a comprehensive, unified, and in-depth overview of the current methodological strategies in computer-aided drug discovery and design. Its main aims are to introduce the theoretical framework and algorithms, discuss the range of validity, strengths and limitations of each methodology, and present applications to real world problems in the drug discovery arena. Special emphasis has been given to the emerging and most pressing methodological challenges in in silico drug