Psychiatric Genomics

• Author : Evangelia Eirini Tsermpini,Martin Alda,George P. Patrinos
• Publisher : Academic Press
• Release : 18 March 2022

Psychiatric Genomics presents and synthesizes available knowledge in the field of psychiatric genomics, offering methodologies to advance new research and aid clinical translation. After providing an introduction to genomics and psychiatry, international experts discuss the genomic basis of schizophrenia, bipolar disorder, depression, personality disorders, anxiety disorders, addictions, eating disorders, and sleep disorders, among other disorders. In addition, recommendations for next steps in clinical implementation and drug discovery are discussed in-depth, with chapters dedicated to pharmacogenomics and antipsychotics, antidepressants and mood

• Author : Peter McGuffin,Michael J Owen,Irving I Gottesman
• Publisher : Oxford University Press
• Release : 23 September 2004

Genetics promises to provide one of the most powerful approaches to understanding the functional pathology of the human brain. This book starts with a brief introduction to the relevant molecular and cellular biology and then moves on to cover the evidence for a genetic contribution to normal and abnormal development and to abnormal behaviour in adult life. The final section covers counselling, ethics and takes a look to the future.

• Author : Thomas Lehner,Bruce L. Miller,Matthew W. State
• Publisher : Academic Press
• Release : 07 June 2016

This foundational work comprehensively examines the current state of the genetics, genomics and brain circuitry of psychiatric and neurological disorders. It consolidates discoveries of specific genes and genomic regions associated with these conditions, the genetic and anatomic architecture of these syndromes, and addresses how recent advances in genomics are leading to a reappraisal of the biology underlying clinical neuroscience. In doing so, it critically examines the promise and limitations of these discoveries toward treatment, and to the interdisciplinary nature of

• Author : Jacob Peedicayil,Dennis R. Grayson,Dimitri Avramopoulos
• Publisher : Academic Press
• Release : 16 August 2021

Epigenetics in Psychiatry, Second Edition covers all major areas of psychiatry in which extensive epigenetic research has been performed, fully encompassing a diverse and maturing field, including drug addiction, bipolar disorder, epidemiology, cognitive disorders, and the uses of putative epigenetic-based psychotropic drugs. Uniquely, each chapter correlates epigenetics with relevant advances across genomics, transcriptomics, and proteomics. The book acts as a catalyst for further research in this growing area of psychiatry. This new edition has been fully revised to address recent

• Author : Bernhard Baune
• Publisher : Academic Press
• Release : 16 October 2019

Personalized Psychiatry presents the first book to explore this novel field of biological psychiatry that covers both basic science research and its translational applications. The book conceptualizes personalized psychiatry and provides state-of-the-art knowledge on biological and neuroscience methodologies, all while integrating clinical phenomenology relevant to personalized psychiatry and discussing important principles and potential models. It is essential reading for advanced students and neuroscience and psychiatry researchers who are investigating the prevention and treatment of mental disorders. Combines neurobiology with basic

• Author : Harry A Brandt,Steven F Crawford
• Publisher : Elsevier Health Sciences
• Release : 28 March 2019

This issue of Psychiatric Clinics, guest edited by Drs. Harry Brandt and Steven Crawford, is the first of two issues dedicated to a comprehensive review of the latest in Eating Disorder diagnosis and treatment. Under the guidance of series consulting editor Dr. Harsh Trivedi, Drs. Brandt and Crawford will cover a number of essential topics, included, but not limited to: Diagnostic categories and criteria and future considerations, Recent Research on Anorexia Nervosa, Recent Research on Bulimia Nervosa, Recent Research on

• Author : Thomas Schulze,Francis McMahon
• Publisher : Oxford University Press
• Release : 06 April 2018

Psychiatrists and other mental health professionals are increasingly confronted with questions about the genetics of psychiatric illness, and the clinical applications of new genetic findings. Psychiatric Genetics: A Primer for Clinical and Basic Scientists addresses these questions through a straightforward introduction to the essentials of psychiatric genetics, complementing more comprehensive textbooks that may seem overwhelming for those new to the field. Written and edited by leaders in the field and the International Society of Psychiatric Genetics (ISPG), the book covers

• Author : Alan F. Schatzberg,Charles B. Nemeroff
• Publisher : American Psychiatric Pub
• Release : 10 May 2017

The American Psychiatric Association Publishing Textbook of Psychopharmacology is an indispensable and comprehensive resource for clinicians and trainees who prescribe psychotropic medications. Updated to reflect the new DSM-5 classification, this revised Fifth Edition maintains the user-friendly structure of its predecessors while offering in-depth coverage of the latest research in pharmacological principles, classes of drugs, and psychiatric disorders. Introductory chapters provide a theoretical grounding in clinical applications, with topics ranging from neurotransmitters to brain imaging in psychopharmacology. The bulk of the

• Author : Ka-Chun Wong
• Publisher : Springer
• Release : 24 October 2016

This contributed volume explores the emerging intersection between big data analytics and genomics. Recent sequencing technologies have enabled high-throughput sequencing data generation for genomics resulting in several international projects which have led to massive genomic data accumulation at an unprecedented pace. To reveal novel genomic insights from this data within a reasonable time frame, traditional data analysis methods may not be sufficient or scalable, forcing the need for big data analytics to be developed for genomics. The computational methods addressed

• Author : Elisabeth B. Binder,Torsten Klengel
• Publisher : Springer Nature
• Release : 12 December 2019

This book provides a unique overview on the most recent developments in initially diverse areas of behavioral genomic research that now start to intertwine to provide more detailed insights into the complex nature of behavior in health and disease. It focuses on our current understanding of genetic and epigenetic mechanisms of brain function and how they contribute to the complex formation of behavioral traits and psychiatric disorders. Readers experience diverse perspectives of the contributing authors starting from the genetic viewpoint

• Author : Jeffrey A. Lieberman,T. Scott Stroup,Diana O. Perkins,Lisa B. Dixon
• Publisher : American Psychiatric Pub
• Release : 30 January 2020

The new edition of The American Psychiatric Association Publishing Textbook of Schizophrenia plumbs the current state of knowledge about the disorder's origin, nature, and treatment in a comprehensive, authoritative, and thoroughly revised text. Schizophrenia is one of the leading causes of disability worldwide and remains among the most challenging and disheartening disorders confronting psychiatrists and other mental health care providers because of its profound effects on patient functioning, its onset just as young adults are launching their lives, and the

• Author : Jay Joseph
• Publisher : Taylor & Francis
• Release : 09 December 2022

Schizophrenia is a widely investigated psychiatric condition, and though there have been claims of gene "associations," decades of molecular genetic studies have failed to produce confirmed causative genes. In this book, Joseph focuses on the methodological shortcomings of schizophrenia genetic research. His findings have major implications not only on how we understand the causes of schizophrenia and other psychiatric conditions, but also on how we understand the causes of human behavior in general. Chapters explore the differing theoretical concepts of

• Author : Yaw A. Frimpong-Mansoh,Caesar A. Atuire
• Publisher : Vernon Press
• Release : 30 July 2019

Bioethics urges us to question and debate fundamental moral issues that arise in health-related sciences. However, as a result of Western dominance and globalization, bioethical thinking and practice has inevitably been shaped and defined by Western theories. With recent discussions centering on the relationship between culture and bioethics, it is important to consider how and to what extent can bioethics reflect and accommodate non-Western values and beliefs? Debatably, many scholars working in the field of ‘African bioethics’ seek to construct

• Author : Jessica D. Tenenbaum,Piper A. Ranallo
• Publisher : Springer Nature
• Release : 18 November 2021

This textbook provides a detailed resource introducing the subdiscipline of mental health informatics. It systematically reviews the methods, paradigms, tools and knowledge base in both clinical and bioinformatics and across the spectrum from research to clinical care. Key foundational technologies, such as terminologies, ontologies and data exchange standards are presented and given context within the complex landscape of mental health conditions, research and care. The learning health system model is utilized to emphasize the bi-directional nature of the translational science

• Author : Nancy C. Andreasen
• Publisher : American Psychiatric Pub
• Release : 03 May 2007

Research Advances in Genetics and Genomics: Implications for Psychiatry introduces mental health professionals to exciting breakthroughs in endophenotypes, animal models, microarrays, and genetic mapping, as well as general strategies for identifying the genetic mechanisms of mental illnesses. Uniquely valuable both as summary and signpost, this concise volume provides a fascinating overview of recent cutting-edge developments in the application of molecular genetics, genomics, and proteomics to the study of psychiatric populations. By reading Research Advances in Genetics and Genomics, you will