Protein Trafficking in Neurons

• Author : Andrew J. Bean
• Publisher : Elsevier
• Release : 27 October 2006

The efficient delivery of cellular constituents to their proper location is of fundamental importance for all cells and is of particular interest to neuroscientists, because of the unique functions and complex architecture of neurons. Protein Trafficking in Neurons examines mechanisms of protein trafficking and the role of trafficking in neuronal functioning from development to plasticity to disease. The book is divided into seven sections that review mechanisms of protein transport, the role of protein trafficking in synapse formation, exo- and

• Author : Anonim
• Publisher : Academic Press
• Release : 12 January 2016

The Neuronal Cytoskeleton, Motor Proteins, and Organelle Trafficking in the Axon, a new volume in the Methods in Cell Biology series continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods in neuronal cells, and includes sections on such topics as actin transport in axons and neurofilament transport. Covers an increasingly appreciated field in cell biology Includes both established and new technologies Contributed by experts in the field

• Author : Anonim
• Publisher : Unknown
• Release : 07 June 2023

Proper neuronal development and function requires precise sorting and delivery of various elements from the soma to the synapse. Important mediators of intracellular transport events are the actin-based class V myosin motors, which are involved in organelle transport in various cell types. Two myosin V family members, myosin Va and Vb, are present in the brain, however, the identity of cargoes transported by these motors is unknown. The objective of this thesis was to conduct molecular and cell biological studies

• Author : Beatriz Alvarez,Miguel Diaz-Hernandez,Douglas Campbell,Irena Vlatkovic
• Publisher : Frontiers Media SA
• Release : 02 August 2022

• Author : Stephen John Moss,Jeremy Henley
• Publisher : Unknown
• Release : 07 June 2023

• Author : Anonim
• Publisher : CSHL Press
• Release : 07 June 1995

Investigators provide an account of how cells control and repair the folding of newly synthesized proteins and transport them correctly to membranes, mitochondria and other cellular addresses. It also provides information on synaptic function, cell movement and other cellular functions.

• Author : Peter H. St.George-Hyslop,William C. Mobley
• Publisher : Springer Science & Business Media
• Release : 03 February 2009

Many adult onset neurodegenerative diseases arise from the accumulation of misfolded peptides. This book examines the role sub-cellular trafficking pathways play in the pathological accumulation of these misfolded proteins and in attempts to clear them.

• Author : Ayesha Murshid
• Publisher : Unknown
• Release : 07 June 2023

"In mammalian cells, two main membrane trafficking pathways, the secretory and endocytic pathways are important for many biological functions. Secretory proteins are synthesized on ribosomes inside the cells, translocated into the ER for proper folding, later mature in the Golgi and continue their journey to the plasma membrane. Endocytosis is defined as a process of vesicle formation from the plasma membrane, where external solutes like nutrients, growth factors and transmembrane proteins are internalized by the cell to endosomal compartments. Internalized

• Author : Stephen John Moss,Jeremy Henley
• Publisher : Unknown
• Release : 07 June 2023

A volume in the Molecular and Cellular Neurobiology series.This book reviews the recent advances in our understanding of the molecular and cellular mechanisms that control the assembly, transport, targeting and anchoring of the protein complexes making up the most important ion channels and receptor families, fundamental to synaptic function. Improvedunderstanding of these processes is expected to reveal novel therapeutic targets relevant to a range of disease states.The first section of the book contains three chapters dealing with cation

• Author : Celia J. Parkyn,King's College London. Guy's, King's and St. Thomas's School of Medicine
• Publisher : Unknown
• Release : 07 June 2023

• Author : Katsuhiko Mikoshiba,Abel Lajtha
• Publisher : Springer Science & Business Media
• Release : 18 May 2009

This volume of the Handbook of Neurochemistry and Molecular Biology focuses on molecular events involved in synapse formation, synaptic plasticity and ongoing neural activity. The volume explores axonal growth cones, synapse development, and mechanisms of LTP and LTD, and calcium dynamics. Particular attention is given to function and trafficking of membrane proteins including various ion channels, aquaporines, gap junctions.

• Author : Nava Segev
• Publisher : Springer Science & Business Media
• Release : 30 May 2010

This book covers the past, present and future of the intra-cellular trafficking field, which has made a quantum leap in the last few decades. It details how the field has developed and evolved as well as examines future directions.

• Author : Rachel Susan Kraut,Guillaume Thibault,Sarita Hebbar,Elisabeth Knust
• Publisher : Frontiers Media SA
• Release : 28 January 2020

• Author : Denis J. Dupré,Terence E. Hébert,Ralf Jockers
• Publisher : Springer Science & Business Media
• Release : 19 November 2012

Main Question: G protein coupled receptors are involved in highly efficient and specific activation of signalling pathways. How do GPCR signalling complexes get assembled to generate such specificity? In order to answer this question, we need to understand how receptors and their signalling partners are synthesized, folded and quality-controlled in order to generate functional proteins. Then, we need to understand how each partner of the signalling complex is selected to join a complex, and what makes this assembly possible. GPCRs

• Author : Anonim
• Publisher : Academic Press
• Release : 05 January 2019

G-Protein-Coupled Receptors, Part B, 2nd Edition, Volume 149, the latest release in the Methods in Cell Biology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers Optical Approaches for Visualization of Arrestin Binding to Muscarinic Receptors, Luciferase Reporter Assay for Unlocking Ligand-mediated Signaling of GPCRs, Assays to Measure GPCR Dependent Cellular Migration, Characterization of the Frizzled GPCRs, Binding Assays for Bradykinin and Angiotensin Receptors, Detection of Misfolded Rhodopsin Aggregates in