Protein Bioinformatics

• Author : Ingvar Eidhammer,William R.. Taylor,Inge Jonassen,William R. Taylor
• Publisher : Wiley-Blackwell
• Release : 13 February 2004

Pairwise global alignment of sequences. Pairwise local alignment and database search. Statical analysis. Multiple global alignment and phylogenetic trees. Scoring matrices. Profiles. Sequence patterns. Structures and structure descriptions. Superposition and Dynamic programming. Geometric techniques. Clustering: Combining local similarities. Significance and assessment of structure comparisons. Multiple structure comparison. Protein structure classification. Structure prediction: Threading. Basics in mathematics, probability and algorithms. Introduction to molecular biology.

• Author : M. Michael Gromiha
• Publisher : Academic Press
• Release : 21 April 2011

One of the most pressing tasks in biotechnology today is to unlock the function of each of the thousands of new genes identified every day. Scientists do this by analyzing and interpreting proteins, which are considered the task force of a gene. This single source reference covers all aspects of proteins, explaining fundamentals, synthesizing the latest literature, and demonstrating the most important bioinformatics tools available today for protein analysis, interpretation and prediction. Students and researchers of biotechnology, bioinformatics, proteomics, protein

• Author : Florencio Pazos,Mónica Chagoyen
• Publisher : Springer
• Release : 28 November 2014

This book describes more than 60 web-accessible computational tools for protein analysis and is totally practical, with detailed explanations on how to use these tools and interpret their results and minimal mentions to their theoretical basis (only when that is required for making a better use of them). It covers a wide range of tools for dealing with different aspects of proteins, from their sequences, to their three-dimensional structures, and the biological networks they are immersed in. The selection of tools

• Author : Daniel John Rigden
• Publisher : Springer Science & Business Media
• Release : 11 December 2008

Proteins lie at the heart of almost all biological processes and have an incredibly wide range of activities. Central to the function of all proteins is their ability to adopt, stably or sometimes transiently, structures that allow for interaction with other molecules. An understanding of the structure of a protein can therefore lead us to a much improved picture of its molecular function. This realisation has been a prime motivation of recent Structural Genomics projects, involving large-scale experimental determination of

• Author : Daniel J. Rigden
• Publisher : Springer
• Release : 06 April 2017

This book is about protein structural bioinformatics and how it can help understand and predict protein function. It covers structure-based methods that can assign and explain protein function based on overall folds, characteristics of protein surfaces, occurrence of small 3D motifs, protein-protein interactions and on dynamic properties. Such methods help extract maximum value from new experimental structures, but can often be applied to protein models. The book also, therefore, provides comprehensive coverage of methods for predicting or inferring protein structure,

• Author : Janusz M. Bujnicki
• Publisher : Springer
• Release : 12 September 2007

This book presents applications of bioinformatics tools that experimental research scientists use in "daily practice." Its interdisciplinary approach combines computational and experimental methods to solve scientific problems. The book begins with reviews of computational methods for protein sequence-structure-function analysis, followed by methods that use experimental data obtained in the laboratory to improve functional predictions.

• Author : Sanguthevar Rajasekaran
• Publisher : Springer
• Release : 22 April 2009

This book constitutes the refereed proceedings of the First International on Bioinformatics and Computational Biology, BICoB 2007, held in New Orleans, LA, USA, in April 2007. The 30 revised full papers presented together with 10 invited lectures were carefully reviewed and selected from 72 initial submissions. The papers address current research in the area of bioinformatics and computational biology fostering the advancement of computing techniques and their application to life sciences in topics such as genome analysis sequence analysis, phylogenetics, structural bioinformatics, analysis of high-throughput

• Author : Jean-Michel Claverie,Cedric Notredame
• Publisher : John Wiley & Sons
• Release : 10 February 2011

Were you always curious about biology but were afraid to sit through long hours of dense reading? Did you like the subject when you were in high school but had other plans after you graduated? Now you can explore the human genome and analyze DNA without ever leaving your desktop! Bioinformatics For Dummies is packed with valuable information that introduces you to this exciting new discipline. This easy-to-follow guide leads you step by step through every bioinformatics task that can

• Author : Gil Alterovitz,Marco Ramoni
• Publisher : John Wiley & Sons
• Release : 20 April 2011

There is an increasing need throughout the biomedical sciences for a greater understanding of knowledge-based systems and their application to genomic and proteomic research. This book discusses knowledge-based and statistical approaches, along with applications in bioinformatics and systems biology. The text emphasizes the integration of different methods for analysing and interpreting biomedical data. This, in turn, can lead to breakthrough biomolecular discoveries, with applications in personalized medicine. Key Features: Explores the fundamentals and applications of knowledge-based and statistical approaches in

• Author : Andreas D. Baxevanis,B. F. Francis Ouellette
• Publisher : John Wiley & Sons
• Release : 24 March 2004

"In this book, Andy Baxevanis and Francis Ouellette . . . haveundertaken the difficult task of organizing the knowledge in thisfield in a logical progression and presenting it in a digestibleform. And they have done an excellent job. This fine text will makea major impact on biological research and, in turn, on progress inbiomedicine. We are all in their debt." —Eric Lander from the Foreword Reviews from the First Edition "...provides a broad overview of the basic tools for sequenceanalysis ... For biologists approaching

• Author : Thomas Hamelryck,Kanti Mardia,Jesper Ferkinghoff-Borg
• Publisher : Springer
• Release : 23 March 2012

This book is an edited volume, the goal of which is to provide an overview of the current state-of-the-art in statistical methods applied to problems in structural bioinformatics (and in particular protein structure prediction, simulation, experimental structure determination and analysis). It focuses on statistical methods that have a clear interpretation in the framework of statistical physics, rather than ad hoc, black box methods based on neural networks or support vector machines. In addition, the emphasis is on methods that deal

• Author : Ingvar Eidhammer,William R.. Taylor,Inge Jonassen,William R. Taylor
• Publisher : Wiley-Blackwell
• Release : 13 February 2004

Pairwise global alignment of sequences. Pairwise local alignment and database search. Statical analysis. Multiple global alignment and phylogenetic trees. Scoring matrices. Profiles. Sequence patterns. Structures and structure descriptions. Superposition and Dynamic programming. Geometric techniques. Clustering: Combining local similarities. Significance and assessment of structure comparisons. Multiple structure comparison. Protein structure classification. Structure prediction: Threading. Basics in mathematics, probability and algorithms. Introduction to molecular biology.

• Author : Caroline St. Clair,Jonathan Visick
• Publisher : Jones & Bartlett Learning
• Release : 10 August 2022

Exploring Bioinformatics: A Project-Based Approach Is Intended For An Introductory Course In Bioinformatics At The Undergraduate Level. Through Hands-On Projects, Students Are Introduced To Current Biological Problems And Then Explore And Develop Bioinformatic Solutions To These Issues. Each Chapter Presents A Key Problem, Provides Basic Biological Concepts, Introduces Computational Techniques To Address The Problem, And Guides Students Through The Use Of Existing Web-Based Tools And Existing Software Solutions. This Progression Prepares Students To Tackle The On-Your-Own Project, Where They Develop

• Author : Jianer Chen,Jianxin Wang,Alexander Zelikovsky
• Publisher : Springer
• Release : 29 April 2011

This volume constitutes the refereed proceedings of the 7th International Symposium on Bioinformatics Research and Applications, ISBRA 2011, held in Changsha, China, in May 2011. The 36 revised full papers presented together with 4 invited talks were carefully reviewed and selected from 92 submissions. Topics presented span all areas of bioinformatics and computational biology, including the development of experimental or commercial systems.

• Author : Anna Tramontano
• Publisher : CRC Press
• Release : 06 December 2006

Guiding readers from the elucidation and analysis of a genomic sequence to the prediction of a protein structure and the identification of the molecular function, Introduction to Bioinformatics describes the rationale and limitations of the bioinformatics methods and tools that can help solve biological problems. Requiring only a limited mathematical and statistical background, the book shows how to efficiently apply these approaches to biological data and evaluate the resulting information. The author, an expert bioinformatics researcher, first addresses the ways