Polycomb Group Proteins

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  • Author : Vincenzo Pirrotta
  • Publisher : Academic Press
  • Pages : 372 pages
  • ISBN : 0128098228
  • Rating : /5 from reviews
CLICK HERE TO GET THIS BOOK >>>Polycomb Group Proteins

Download or Read online Polycomb Group Proteins full in PDF, ePub and kindle. this book written by Vincenzo Pirrotta and published by Academic Press which was released on 01 January 2017 with total page 372 pages. We cannot guarantee that Polycomb Group Proteins book is available in the library, click Get Book button and read full online book in your kindle, tablet, IPAD, PC or mobile whenever and wherever You Like. Polycomb Group Proteins is a comprehensive volume detailing the mechanisms that are key to the management of genome function in many different contexts, from embryonic stem cells to terminal differentiation. The book discusses the regulation of cell lineages, cell proliferation, apoptosis, X chromosome inactivation, and most major genome programming choices. In the last few years, the biochemical understanding of PRC1-type complexes has greatly expanded in terms of the number of components involved and the intricacies of their interactions. The functionalities of these various complexes and their components are not all well understood, but recent work has shown an important division of labor and roles in the recruitment of stable binding in the ability to lay the groundwork of histone modifications and in the epigenetic maintenance of repressed states. In an effort to provide clarity in this topical research area, the book provides a cluster of chapters that deal with variant PRC1 complexes, their taxonomy, their components, their interactions, and what is known of their functions. Provides topical coverage on accessory components that are known to be involved in PcG recruitment in Drosophila and their less understood role in mammals Includes dedicated sections on PRC1 complexes and PRC2 complexes for quick reference Features the role of RNA molecules in different aspects of Polycomb proteins involvement in epigenetic regulation, beginning with the key role of the Xist RNA in recruiting and spreading PcG complexes on the inactive X chromosome

Polycomb Group Proteins

Polycomb Group Proteins
  • Author : Chiara Lanzuolo,Beatrice Bodega
  • Publisher : Humana Press
  • Release : 14 September 2016
GET THIS BOOK Polycomb Group Proteins

This volume presents the most recent technologies used in the Polycomb Group Proteins (PcG) field. Chapters detail state-of-the-art methods, creating a unique and comprehensive reference source for investigating Polycomb function in the nucleus. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Polycomb Group Proteins: Method and Protocols

Polycomb Group Proteins

Polycomb Group Proteins
  • Author : Beatrice Bodega,Chiara Lanzuolo
  • Publisher : Unknown
  • Release : 13 June 2021
GET THIS BOOK Polycomb Group Proteins

This volume presents the most recent technologies used in the Polycomb Group Proteins (PcG) field. Chapters detail state-of-the-art methods, creating a unique and comprehensive reference source for investigating Polycomb function in the nucleus. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Polycomb Group Proteins: Method and Protocols

Polycomb Group Proteins

Polycomb Group Proteins
  • Author : Vincenzo Pirrotta
  • Publisher : Academic Press
  • Release : 01 January 2017
GET THIS BOOK Polycomb Group Proteins

Polycomb Group Proteins is a comprehensive volume detailing the mechanisms that are key to the management of genome function in many different contexts, from embryonic stem cells to terminal differentiation. The book discusses the regulation of cell lineages, cell proliferation, apoptosis, X chromosome inactivation, and most major genome programming choices. In the last few years, the biochemical understanding of PRC1-type complexes has greatly expanded in terms of the number of components involved and the intricacies of their interactions. The

Genome wide Intergenic Repression by Polycomb Group Proteins

Genome wide Intergenic Repression by Polycomb Group Proteins
  • Author : Hungoo Lee
  • Publisher : Unknown
  • Release : 13 June 2021
GET THIS BOOK Genome wide Intergenic Repression by Polycomb Group Proteins

Polycomb group (PcG) proteins have been studied as epigenetic regulators of diverse developmental regulatory genes in various organisms. PcG proteins form two major complexes: the Polycomb repressive complex 2 (PRC2) which includes Enhancer of zeste (E(Z)) that methylates the lysine 27 residue of histone H3 (H3K27) and the Polycomb repressive complex 1 (PRC1) which preferentially binds to tri-methylated H3K27 (H3K27me3). Recent genome-wide analysis revealed that the PcG proteins stably bind to hundreds of genomic loci with strong H3

Long Non coding RNAs Interact with PRC1 to Impact Polycomb Group Protein Recruitment and Expression of Polycomb Regulated Genes

Long Non coding RNAs Interact with PRC1 to Impact Polycomb Group Protein Recruitment and Expression of Polycomb Regulated Genes
  • Author : Mridula Kumari Ray
  • Publisher : Unknown
  • Release : 13 June 2021
GET THIS BOOK Long Non coding RNAs Interact with PRC1 to Impact Polycomb Group Protein Recruitment and Expression of Polycomb Regulated Genes

Overall, this protocol is the first of its kind to efficiently identify de novo interactions between the PcG proteins and lncRNAs which impact PcG binding or PcG target gene expression.