Phytochemicals as Lead Compounds for New Drug Discovery

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  • Author : Chukwuebuka Egbuna
  • Publisher : Elsevier
  • Pages : 378 pages
  • ISBN : 0128178914
  • Rating : /5 from reviews
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Download or Read online Phytochemicals as Lead Compounds for New Drug Discovery full in PDF, ePub and kindle. this book written by Chukwuebuka Egbuna and published by Elsevier which was released on 07 September 2019 with total page 378 pages. We cannot guarantee that Phytochemicals as Lead Compounds for New Drug Discovery book is available in the library, click Get Book button and read full online book in your kindle, tablet, IPAD, PC or mobile whenever and wherever You Like. Phytochemicals as Lead Compounds for New Drug Discovery presents complete coverage of the recent advances in the discovery of phytochemicals from medicinal plants as models to the development of new drugs and chemical entities. Functional bioactive compounds of plant origin have been an invaluable source for many human therapeutic drugs and have played a major role in the treatment of diseases around the world. These compounds possess enormous structural and chemical diversity and have led to many important discoveries. This book presents fundament concepts and factors affecting the choice for plant-based products, as well as recent advances in computer-aided drug discovery and FDA drug candidacy acceptance criteria. It also details the various bioactive lead compounds and molecular targets for a range of life-threatening diseases including cancer, diabetes, and neurodegenerative diseases. Written by a global team of experts, Phytochemicals as Lead Compounds for New Drug Discovery is an ideal resource for drug developers, phytochemists, plant biochemists, food and medicinal chemists, nutritionists and toxicologists, chemical ecologists, taxonomists, analytical chemists, and other researchers in those fields. It will also be very valuable to professors, students, and researchers in this domain. Presents fundamental concepts and factors affecting choice for plant-based products Details the FDA drug candidacy acceptance criteria, including bottlenecks and way forward Highlights recent advances in computational-based drug discovery Focuses on the discovery of new drugs and potential druggable targets for the treatment of chronic diseases of world importance

Phytochemicals as Lead Compounds for New Drug Discovery

Phytochemicals as Lead Compounds for New Drug Discovery
  • Author : Chukwuebuka Egbuna,Shashank Kumar,Jonathan C. Ifemeje,Shahira M. Ezzat,Saravanan Kaliyaperumal
  • Publisher : Elsevier
  • Release : 07 September 2019
GET THIS BOOK Phytochemicals as Lead Compounds for New Drug Discovery

Phytochemicals as Lead Compounds for New Drug Discovery presents complete coverage of the recent advances in the discovery of phytochemicals from medicinal plants as models to the development of new drugs and chemical entities. Functional bioactive compounds of plant origin have been an invaluable source for many human therapeutic drugs and have played a major role in the treatment of diseases around the world. These compounds possess enormous structural and chemical diversity and have led to many important discoveries. This

Neglected Tropical Diseases and Phytochemicals in Drug Discovery

Neglected Tropical Diseases and Phytochemicals in Drug Discovery
  • Author : Chukwuebuka Egbuna,Muhammad Akram,Jonathan Chinenye Ifemeje
  • Publisher : John Wiley & Sons
  • Release : 12 October 2021
GET THIS BOOK Neglected Tropical Diseases and Phytochemicals in Drug Discovery

Explore novel drug discovery updates from medicinal plants to help fight the devastating effects of neglected tropical diseases Neglected Tropical Diseases and Phytochemicals in Drug Discovery delivers a comprehensive exploration of the drug discovery process as it pertains to neglected tropical diseases. The book covers recent advancements in drug discovery, as well as druggable targets and new challenges facing the industry. It offers readers expansive discussions of specific diseases, including protozoan, helminth, bacterial, viral, fungal, and ectoparasitic infections. This book

Plant Bioactives as Natural Panacea against Age induced Diseases Nutraceuticals and Functional Lead Compounds for Drug Development

Plant Bioactives as Natural Panacea against Age induced Diseases  Nutraceuticals and Functional Lead Compounds for Drug Development
  • Author : Kanti Bhooshan Pandey,Maitree Suttajit
  • Publisher : Elsevier
  • Release : 15 June 2022
GET THIS BOOK Plant Bioactives as Natural Panacea against Age induced Diseases Nutraceuticals and Functional Lead Compounds for Drug Development

Plant Bioactives as Natural Panacea Against Age-induced Diseases: Nutraceuticals and Functional Lead Compounds for Drug Development presents in detail the complications of aging and the bioactive phytochemicals that in specific herbal formulations including beverages can mitigate them. The book extensively describes the current information not only on the role of plant bioactive components in delaying or preventing the aging process and associated complications, but also the different strategies and scientific evidence of the possible synergistic effects of these studies, enabling

Dietary Phytochemicals

Dietary Phytochemicals
  • Author : Chukwuebuka Egbuna,Sadia Hassan
  • Publisher : Springer Nature
  • Release : 05 December 2021
GET THIS BOOK Dietary Phytochemicals

This book presents comprehensive coverage on the importance of good nutrition in the treatment and management of obesity, cancer and diabetes. Naturally occurring bioactive compounds are ubiquitous in most dietary plants available to humans and provide opportunities for the management of diseases. The text provides information about the major causes of these diseases and their association with nutrition. The text also covers the role of dietary phytochemicals in drug development and their pathways. Later chapters emphasize novel bioactive compounds as

Machine Learning and Analytics in Healthcare Systems

Machine Learning and Analytics in Healthcare Systems
  • Author : Himani Bansal,Balamurugan Balusamy,T. Poongodi,Firoz Khan KP
  • Publisher : CRC Press
  • Release : 01 July 2021
GET THIS BOOK Machine Learning and Analytics in Healthcare Systems

This book provides applications of machine learning in healthcare systems and seeks to close the gap between engineering and medicine. It will combine the design and problem-solving skills of engineering with health sciences, in order to advance healthcare treatment. The book will include areas such as diagnosis, monitoring, and therapy. The book will provide real-world case studies, gives a detailed exploration of applications in healthcare systems, offers multiple perspectives on a variety of disciplines, while also letting the reader know

Functional Foods and Nutraceuticals

Functional Foods and Nutraceuticals
  • Author : Chukwuebuka Egbuna,Genevieve Dable Tupas
  • Publisher : Springer Nature
  • Release : 24 August 2020
GET THIS BOOK Functional Foods and Nutraceuticals

Functional foods and nutraceuticals are food products that naturally offer or have been modified to offer additional health benefits beyond basic nutrition. As such products have surged in popularity in recent years, it is crucial that researchers and manufacturers understand the concepts underpinning functional foods and the opportunity they represent to improve human health, reduce healthcare costs, and support economic development worldwide. Functional Foods and Nutraceuticals: Bioactive Components, Formulations and Innovations presents a guide to functional foods from experienced professionals

Influence of Nutrients Bioactive Compounds and Plant Extracts in Liver Diseases

Influence of Nutrients  Bioactive Compounds  and Plant Extracts in Liver Diseases
  • Author : Seyed Moayed Alavian,Seyed Mohammad Nabavi,Seyed Fazel Nabavi,Ana Sanches Silva
  • Publisher : Academic Press
  • Release : 20 November 2020
GET THIS BOOK Influence of Nutrients Bioactive Compounds and Plant Extracts in Liver Diseases

Influence of Nutrients, Bioactive Compounds, and Plant Extracts in Liver Diseases provides evidence-based knowledge of the mechanism of action of natural compounds, as well as the relation of structure and function of phytochemicals in hepatitis B and C, fatty liver disease, nonalcoholic fatty liver disease, liver cancer, biliary cirrhosis, and primary sclerosing cholangitis. The effect of phytochemicals in the hepatotoxicity of drugs is also addressed. Written for health professionals seeking reliable and up-to-date information on the beneficial or toxic effects

Role of Oxidative Stress in Pathophysiology of Diseases

Role of Oxidative Stress in Pathophysiology of Diseases
  • Author : Pawan K. Maurya,Kamal Dua
  • Publisher : Springer Nature
  • Release : 15 June 2020
GET THIS BOOK Role of Oxidative Stress in Pathophysiology of Diseases

This book illustrates the importance and significance of oxidative stress in the pathophysiology of various human diseases. The book initially introduces the phenomenon of oxidative stress, basic chemical characteristics of the species involved and summarizes the cellular oxidant and anti-oxidant system and the cellular effects and metabolism of the oxidative stress. In addition, it reviews the current understanding of the potential impact of oxidative stress on telomere shortening, aging, and age-related diseases. It also examines the role of oxidative stress

Medicinal Plants in the Asia Pacific for Zoonotic Pandemics Volume 1

Medicinal Plants in the Asia Pacific for Zoonotic Pandemics  Volume 1
  • Author : Christophe Wiart
  • Publisher : CRC Press
  • Release : 30 June 2021
GET THIS BOOK Medicinal Plants in the Asia Pacific for Zoonotic Pandemics Volume 1

Medicinal Plants in the Asia Pacific for Zoonotic Pandemics provides an unprecedented, comprehensive overview of the phylogeny, botany, ethnopharmacology, and pharmacology of more than 100 plants used in the traditional medical systems of Asia and Pacific. It discusses their actions and potentials against viruses, bacteria, and fungi that represent a threat of epidemic and pandemic diseases, with an emphasis on the molecular basis and cellular pathways. This book presents scientific names, the botanical classification, traditional medicinal uses, active chemical constituents, and

Phytochemistry the Military and Health

Phytochemistry  the Military and Health
  • Author : Andrew G. Mtewa,Chukwuebuka Egbuna
  • Publisher : Elsevier
  • Release : 02 March 2021
GET THIS BOOK Phytochemistry the Military and Health

Phytochemistry, the Military and Health: Phytotoxins and Natural Defenses comes as a response to the gap that there has for so long existed between phytochemistry and survival of both service personnel and civilian communities during and after conflicts. Armed conflicts cause a lot of devastation to communities and should be avoided as much as it can be possible. The devastation is usually evident in service provisions such as Health, Education, Water, and Food among many others. Both service personnel and

Nutrition Food and Diet in Ageing and Longevity

Nutrition  Food and Diet in Ageing and Longevity
  • Author : Suresh I. S. Rattan,Gurcharan Kaur
  • Publisher : Springer Nature
  • Release : 04 November 2021
GET THIS BOOK Nutrition Food and Diet in Ageing and Longevity

This edited volume is a compilation of 30 articles discussing what constitutes food for health and longevity. The aim is to provide up-to-date information, insights, and future tendencies in the ongoing scientific research about nutritional components, food habits and dietary patterns in different cultures. The health-sustaining and health-promoting effects of food are certainly founded in its overall composition of macronutrients and micronutrients. However, the consumption of these nutrients is normally in the form of raw or prepared food from the animal

Phytochemical Diversity

Phytochemical Diversity
  • Author : E. Chrystal
  • Publisher : Unknown
  • Release : 05 December 1997
GET THIS BOOK Phytochemical Diversity

While the study of the chemicals produced by plants is arguably one of the oldest of the natural product sciences, current global concerns regarding the disappearance of biodiversity, along with the availability of methodology for systematic genetic manipulation and plant tissue culture, have rekindled industrial interest in phytochemical screening. Phytochemical Diversity gives a comprehensive overview of recent discoveries and developments of new products from plants that have potential utility in the pharmaceutical, agrochemical and cosmetic industries. It covers such areas

Computational Intelligence in Healthcare

Computational Intelligence in Healthcare
  • Author : Amit Kumar Manocha,Shruti Jain,Mandeep Singh (MD),Sudip Paul
  • Publisher : Springer Nature
  • Release : 05 December 2021
GET THIS BOOK Computational Intelligence in Healthcare

Artificial intelligent systems, which offer great improvement in healthcare sector assisted by machine learning, wireless communications, data analytics, cognitive computing, and mobile computing provide more intelligent and convenient solutions and services. With the help of the advanced techniques, now a days it is possible to understand human body and to handle & process the health data anytime and anywhere. It is a smart healthcare system which includes patient, hospital management, doctors, monitoring, diagnosis, decision making modules, disease prevention to meet the

Natural Bio active Compounds

Natural Bio active Compounds
  • Author : Mallappa Kumara Swamy,Mohd Sayeed Akhtar
  • Publisher : Springer Nature
  • Release : 19 September 2019
GET THIS BOOK Natural Bio active Compounds

Nature has consistently provided human beings with bioactive compounds that can be used directly as drugs or indirectly as drug leads. Some of the major classes of natural bioactive compounds include phenolics, alkaloids, tannins, saponins, lignin, glycosides, terpenoids, and many more. They possess a broad range of biological activities and are primarily useful in the treatment of various health issues. At the same time, the search for new and novel drugs is never-ending and, despite major advances in synthetic chemistry,

Plant Natural Products for Human Health

Plant Natural Products for Human Health
  • Author : Chun-Tao Che,Hongjie Zhang
  • Publisher : MDPI
  • Release : 21 March 2019
GET THIS BOOK Plant Natural Products for Human Health

Plants have served mankind as an important source of foods and medicines. While we all consume plants and their products for nutritional support, a majority of the world population also rely on botanical remedies to meet their health needs, either as their own “traditional medicine” or as “complementary and alternative medicine”. From a pharmaceutical point of view, many compounds obtained from plant sources have long been known to possess bio/pharmacological activities, and historically, plants have yielded many important drugs