Pharmacoepigenetics

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  • Author : Anonim
  • Publisher : Academic Press
  • Pages : 983 pages
  • ISBN : 0128139404
  • Rating : /5 from reviews
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Download or Read online Pharmacoepigenetics full in PDF, ePub and kindle. this book written by Anonim and published by Academic Press which was released on 04 June 2019 with total page 983 pages. We cannot guarantee that Pharmacoepigenetics book is available in the library, click Get Book button and read full online book in your kindle, tablet, IPAD, PC or mobile whenever and wherever You Like. Pharmacoepigenetics, Volume Eleven provides a comprehensive volume on the role of epigenetics and epigenomics in drug discovery and development, providing a detailed, but accessible, view of the field, from basic principles, to applications in disease therapeutics. Leading international researchers from across academia, clinical settings and the pharmaceutical industry discuss the influence of epigenetics and epigenomics in human pathology, epigenetic biomarkers for disease prediction, diagnosis, and treatment, current epigenetic drugs, and the application of epigenetic procedures in drug development. Throughout the book, chapter authors offer a balanced and objective discussion of the future of pharmacoepigenetics and its crucial contribution to the growth of precision and personalized medicine. Fully examines the influence of epigenetics and epigenomics in human pathology, epigenetic biomarkers for disease prediction, diagnosis, treatment, current epigenetic drugs and the application of epigenetic procedures in drug development Features chapter contributions from leading international researchers in academia, clinical settings and the pharmaceutical industry Instructs researchers, students and clinicians on how to better interpret and employ pharmacoepigenetics in drug development, efficiency and safety Provides a balanced and objective discussion of the future of pharmacoepigenetics and its crucial role in precision medicine

Pharmacoepigenetics

Pharmacoepigenetics
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 04 June 2019
GET THIS BOOK Pharmacoepigenetics

Pharmacoepigenetics, Volume Eleven provides a comprehensive volume on the role of epigenetics and epigenomics in drug discovery and development, providing a detailed, but accessible, view of the field, from basic principles, to applications in disease therapeutics. Leading international researchers from across academia, clinical settings and the pharmaceutical industry discuss the influence of epigenetics and epigenomics in human pathology, epigenetic biomarkers for disease prediction, diagnosis, and treatment, current epigenetic drugs, and the application of epigenetic procedures in drug development. Throughout the

Medical Epigenetics

Medical Epigenetics
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 27 August 2021
GET THIS BOOK Medical Epigenetics

Medical Epigenetics, Second Edition provides a comprehensive analysis of epigenetics in health management, across a broad spectrum of disease categories and specialties, and with a focus on human systems, epigenetic diseases that affect these systems, and evolving modes of epigenetic-based treatment. Here, more than 40 leading researchers examine how each human system is affected by epigenetic maladies, offering an all-in-one resource on medical epigenetics not only for those directly involved with health care, but investigators in life sciences, biotech companies, graduate

Pharmacogenomics

Pharmacogenomics
  • Author : Yui-Wing Francis Lam,Larisa H. Cavallari
  • Publisher : Academic Press
  • Release : 12 February 2013
GET THIS BOOK Pharmacogenomics

Pharmacogenomics: Challenges and Opportunities in Therapeutic Implementation includes discussions and viewpoints from the academic, regulatory, pharmaceutical, clinical, socio-ethical and economic perspectives. Each chapter presents an overview of the potential or opportunity within the areas discussed and also outlines foreseeable challenges and limitations in moving pharmacogenomics into drug development and direct therapeutic applications. This edited book contains review questions for a more in-depth analysis of the implications of pharmacogenomics and discussion points to generate ideas on best to move the field

Personalized Epigenetics

Personalized Epigenetics
  • Author : Trygve Tollefsbol
  • Publisher : Academic Press
  • Release : 28 April 2015
GET THIS BOOK Personalized Epigenetics

Personalized Epigenetics discusses the core translatability of epigenetics to health management of individuals who have unique variations in their epigenetic signatures that can guide both disorder and disease prevention and therapy. The book details inter-individual variability in the major epigenetic process in humans consisting of DNA methylation, histone modifications, and noncoding RNA, and the diagnostic, prognostic, and therapeutic potential of the field, it also reviews the impact of the environment on epigenetic variations among individuals and the role of pharmacology

Topics on Drug Metabolism

Topics on Drug Metabolism
  • Author : James Paxton
  • Publisher : BoD – Books on Demand
  • Release : 22 February 2012
GET THIS BOOK Topics on Drug Metabolism

In order to avoid late-stage drug failure due to factors such as undesirable metabolic instability, toxic metabolites, drug-drug interactions, and polymorphic metabolism, an enormous amount of effort has been expended by both the pharmaceutical industry and academia towards developing more powerful techniques and screening assays to identify the metabolic profiles and enzymes involved in drug metabolism. This book presents some in-depth reviews of selected topics in drug metabolism. Among the key topics covered are: the interplay between drug transport and

Clinical DNA Variant Interpretation

Clinical DNA Variant Interpretation
  • Author : Conxi Lázaro,Jordan Lerner-Ellis,Amanda Spurdle
  • Publisher : Academic Press
  • Release : 27 February 2021
GET THIS BOOK Clinical DNA Variant Interpretation

Clinical DNA Variant Interpretation: Theory and Practice, a new volume in the Translational and Applied Genomics series, covers foundational aspects, modes of analysis, technology, disease and disorder specific case studies, and clinical integration. This book provides a deep theoretical background, as well as applied case studies and methodology, enabling researchers, clinicians and healthcare providers to effectively classify DNA variants associated with disease and patient phenotypes. Practical chapters discuss genomic variant interpretation, terminology and nomenclature, international consensus guidelines, population allele frequency,

Prognostic Epigenetics

Prognostic Epigenetics
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 01 November 2019
GET THIS BOOK Prognostic Epigenetics

This volume provides comprehensive information on how mapping an individual’s epigenome can be medically relevant and holds the potential to improve preventive medicine and precision therapeutics at an early-stage (prior to disease onset). In order to advance clinical adoption of the recently developed epigenetic approaches, it is necessary for translational scientists, clinicians, and students to gain a better understanding about epigenetic mechanisms that are associated with a particular disorder; and to be able to effectively identify biomarkers that can

Translating Epigenetics to the Clinic

Translating Epigenetics to the Clinic
  • Author : Jeffrey Laurence
  • Publisher : Academic Press
  • Release : 30 December 2016
GET THIS BOOK Translating Epigenetics to the Clinic

Translating Epigenetics to the Clinic reviews current methodological tools and experimental approaches used by leading translational researchers seeking to use epigenetics as a clinical model. It organizes epigenetics into disease treatment areas with a major focus on oncology, and with much coverage of pervasive treatment categories such as diabetes, as well as the ‘diseases of modernity’—including pharmacological addiction, dementia, and ageing. Pedagogically, the work concentrates on the latest knowledge, laboratory techniques, and experimental approaches used by translational research leaders

Handbook of Epigenetics

Handbook of Epigenetics
  • Author : Trygve Tollefsbol
  • Publisher : Academic Press
  • Release : 21 November 2010
GET THIS BOOK Handbook of Epigenetics

Epigenetics is considered by many to be the "new genetics" because of the overwhelming evidence of the contribution of non-genetic factors such as nutrition, environment, and chemical exposure on gene expression. The effects of epigenetics are vast, including tissue/organ regeneration, X-chromosome inactivation, and stem cell differentiation and genomic imprinting and aging. Aberrations of epigenetics influence many diseases for which clinical intervention is already in place, and many novel epigenetic therapies for cancer, immune disorders, neurological and metabolic disorders, and

Epigenetics and Reproductive Health

Epigenetics and Reproductive Health
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 12 September 2020
GET THIS BOOK Epigenetics and Reproductive Health

Epigenetics and Reproductive Health, a new volume in the Translational Epigenetics series, provides a thorough overview and discussion of epigenetics in reproduction and implications for reproductive medicine. Twenty international researchers discuss epigenetic mechanisms operating during the formation of male and female gametes, fertilization and subsequent embryo and placental development, particularly in mammals and transgenerational epigenetic inheritance. This volume also addresses aberrant epigenetic changes influencing male and female infertility, pregnancy related disorders, and those potentially linked to therapeutic manipulations and assisted

Alzheimer s Disease Drug Development

Alzheimer s Disease Drug Development
  • Author : Jeffrey Cummings,Jefferson Kinney,Howard Fillit
  • Publisher : Cambridge University Press
  • Release : 31 March 2022
GET THIS BOOK Alzheimer s Disease Drug Development

Alzheimer's Disease (AD) is a growing global public health challenge. The development of new therapies is urgently needed, and a complex ecosystem of organizations has grown to facilitate AD drug discovery and development. Masterfully collating information on the drug development ecosystem, this book emphasizes the contributions of each aspect in the pipeline with a uniform approach to chapters, enabling readers to access relevant information quickly. Topics covered include the use of non-clinical laboratory studies, biomarker development, artificial intelligence, design and

Epigenetics of Stress and Stress Disorders

Epigenetics of Stress and Stress Disorders
  • Author : Nagy Youssef
  • Publisher : Academic Press
  • Release : 25 February 2022
GET THIS BOOK Epigenetics of Stress and Stress Disorders

Epigenetics of Stress and Stress Disorders, Volume 31 in the Translational Epigenetics series, examines the epigenetic mechanisms involved in modifying DNA or gene expression following prolonged stress and/or trauma. Sections introduce both genetic and psychiatric foundations, including modes of epigenetic modification and gene expression that result from stress, as well as the medical knowledge required to understand stress related disorders and resilience. From here, chapters discuss epigenetic research techniques applied in recent studies, including epigenome-wide association studies (EWAS) of PTSD

Epigenetics of Aging and Longevity

Epigenetics of Aging and Longevity
  • Author : Alexey Moskalev,Alexander M. Vaiserman
  • Publisher : Academic Press
  • Release : 17 November 2017
GET THIS BOOK Epigenetics of Aging and Longevity

Epigenetics of Aging and Longevity provides an in-depth analysis of the epigenetic nature of aging and the role of epigenetic factors in mediating the link between early-life experiences and life-course health and aging. Chapters from leading international contributors explore the effect of adverse conditions in early-life that may result in disrupted epigenetic pathways, as well as the potential to correct these disrupted pathways via targeted therapeutic interventions. Intergenerational epigenetic inheritance, epigenetic drug discovery, and the role of epigenetic mechanisms in

10 Years of Pharmacogenetics and Pharmacogenomics

10 Years of Pharmacogenetics and Pharmacogenomics
  • Author : Jose Agundez
  • Publisher : Frontiers Media SA
  • Release : 08 July 2020
GET THIS BOOK 10 Years of Pharmacogenetics and Pharmacogenomics

The Specialty Section “Pharmacogenetics and Pharmacogenomics” makes part of two different Journals: Frontiers in Pharmacology and Frontiers in Genetics. This Specialty Section focuses on the mechanisms by which genetic variations influence drug effects and adverse drug events, and cover basic research, clinical translation, applications in drug development and regulatory issues related to this field. Also, studies addressing the role of other factors such as epigenetics, phenotypic factors or drug-drug interactions on drug pharmacokinetics or pharmacodynamics are welcome. The editorial board

User Driven Healthcare Concepts Methodologies Tools and Applications

User Driven Healthcare  Concepts  Methodologies  Tools  and Applications
  • Author : Management Association, Information Resources
  • Publisher : IGI Global
  • Release : 31 January 2013
GET THIS BOOK User Driven Healthcare Concepts Methodologies Tools and Applications

User-Driven Healthcare: Concepts, Methodologies, Tools, and Applications provides a global discussion on the practice of user-driven learning in healthcare and connected disciplines and its influence on learning through clinical problem solving. This book brings together different perspectives for researchers and practitioners to develop a comprehensive framework of user-driven healthcare.