Peptide and Protein Delivery

• Author : Chris Van Der Walle
• Publisher : Academic Press
• Release : 12 May 2011

The growing area of peptide and protein therapeutics research is of paramount importance to medical application and advancement. A needed reference for entry level researchers and researchers working in interdisciplinary / collaborative projects, Peptide and Protein Delivery addresses the current and emerging routes for delivery of therapeutics. Covering cerebral delivery, pulmonary delivery, transdermal delivery, intestinal delivery, ocular delivery, parenteral delivery, and nasal delivery, this resource offers an overview of the main routes in therapeutics. Researchers across biochemistry, pharmaceutical, molecular biology, cell

• Author : Ajay K. Banga
• Publisher : CRC Press
• Release : 14 September 2005

Upon publication of the first edition of Therapeutic Peptides and Proteins ten years ago there were only 19 biotechology medicines on the market. Currently there are more than 100, with at least 400 more in various stages of development. That alone would be grounds for a new edition. Add to that the fact that it is still difficult to find up

• Author : Vincent Lee
• Publisher : CRC Press
• Release : 19 November 1990

This reference/text covers fundamentals of peptide and protein drug delivery, including such considerations as synthesis, physical chemistry and biochemistry, analysis, proteolytic and transport constraints, pharmacokinetics, and pharmacodynamics; bioavailability from routes of administration, detai

• Author : Kenneth L. Andus,Thomas L. Raub
• Publisher : Springer
• Release : 24 October 2012

In response to the tremendous increase in the number of protein and peptide drugs, this treatise critically reviews transport and metabolism mechanisms relating to the delivery of endogenous and recombinant proteins to mammalian organs, tissues, and cells. It will promote fruitful collaboration among academic and industrial scientists in the fields of pharmacology, cell biology, biochemistry, physiology, and immunology.

• Author : Randall J. Mrsny,Ann Daugherty
• Publisher : CRC Press
• Release : 19 October 2009

Addressing the increased use of protein and peptide candidates as treatments for previously untreatable diseases, this comprehensive and progressive source provides the reader with a roadmap to an increased understanding of issues critical for successfully developing a protein or peptide therapeutic candidate. Proteins and Peptides is

• Author : S.S. Davis,Lisbeth Illum,E. Tomlinson
• Publisher : Springer Science & Business Media
• Release : 11 November 2013

Recent years have seen enormous advances in the field of protein and peptide engineering and a greater understanding in the way in which biological response modifiers function in the body. It is now possible through the use of recombinant DNA techniques, or by solid phase protein synthesis, to produce significant quantities of a wide variety of regulatory agents that are therapeutically applicable. The list of these response modifiers expands almost daily to include interferons, macrophage activation factors, neuropeptides and agents

• Author : Anonim
• Publisher : Unknown
• Release : 24 September 1998

• Author : Akwete Adjei
• Publisher : CRC Press
• Release : 08 July 1997

This exhaustive reference-the first book of its kind to describe in detail the functionality of the human respiratory tract and its impact on both local and systemic delivery of biotherapeutic and macromolecular drug systems-offers comprehensive analyses of peptide and protein drug delivery through the lung. Summarizes over 130 patents granted worldwide on alternative systems for pulmonary delivery of therapeutic drugs-especially peptides and proteins! Examining macromolecular drug delivery as an efficient, patient-friendly, and cost-effective method of treatment, Inhalation Delivery of Therapeutic Peptides

• Author : Vincent Lee
• Publisher : CRC Press
• Release : 01 February 1995

• Author : Vincent H. L. Lee
• Publisher : Marcel Dekker Incorporated
• Release : 01 November 1979

• Author : Somnath Singh
• Publisher : Unknown
• Release : 24 September 2021

• Author : Ajay K. Banga
• Publisher : CRC Press
• Release : 23 April 2015

There are more than 500 biopharmaceuticals on the market, including more than 200 therapeutic proteins, making biologics the fastest growing sector in the biopharmaceutical market. These products include more than 40 monoclonal antibodies, for indications ranging from treatment or mitigation of various types of cancer to rheumatoid arthritis. The clinical application of these therapeutic peptides and proteins is limited by several problems, such as lack of physical and chemical stability or the lack of desirable attributes for adequate absorption or distribution. Thus, as

• Author : Kenneth L. Andus,Thomas L. Raub
• Publisher : Springer Science & Business Media
• Release : 06 December 2012

In response to the tremendous increase in the number of protein and peptide drugs, this treatise critically reviews transport and metabolism mechanisms relating to the delivery of endogenous and recombinant proteins to mammalian organs, tissues, and cells. It will promote fruitful collaboration among academic and industrial scientists in the fields of pharmacology, cell biology, biochemistry, physiology, and immunology.

• Author : Hani H. Sarraf,King's College London. Chelsea Department of Pharmacy
• Publisher : Unknown
• Release : 24 September 1999

• Author : Eugene J. McNally,Eugene McNally,Jayne E. Hastedt
• Publisher : CRC Press
• Release : 26 October 2007

This title is intended to assist pharmaceutical scientists in the development of stable protein formulations during the early stages of the product development process, providing a comprehensive review of mechanisms and causes of protein instability in formulation development, coverage of accelerated stability testing methods and relevant analytical methods, and an overview of the drug substance manufacturing process. Preformulation and the development of traditional solutions and lyophilized formulations frequently used for intravenous delivery and non-traditional formulations are also addressed. Because many