Overcoming Ovarian Cancer Chemoresistance

Overcoming Ovarian Cancer Chemoresistance Book PDF
✏Book Title : Overcoming Ovarian Cancer Chemoresistance
✏Author : Goli Samimi
✏Publisher : Academic Press
✏Release Date : 2020-11-19
✏Pages : 188
✏ISBN : 9780128198414
✏Available Language : English, Spanish, And French

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✏Overcoming Ovarian Cancer Chemoresistance Book Summary : Overcoming Ovarian Cancer Chemoresistance presents non-overlapping review chapters that discuss the state of the field in overcoming chemoresistance of ovarian cancer and treatment options before and following recurrence, considering the genetic makeup of the ovarian cancer patient and her tumor. With the uptake of both germline and somatic gene testing, clinicians can obtain a more comprehensive understanding of ovarian tumors and this book provides information to link the genetic makeup of a tumor (or patient) with the best available treatment. The book discusses topics such as strategies to fight chemo-resistance in ovarian cancer, circulating DNA as a monitor of response, BRCA mutations, ovarian cancer stem cells, immunotherapy and vaccines. Additionally, it brings a list of promising agents at clinical and pre-clinical stage that will impact the treatment in the near future. This book is a valuable source for cancer researchers, oncologists and several members of biomedical field who need to understand how to battle chemoresistance in ovarian cancer. Provides a comprehensive view of both biological and genetic determinants of resistance, as well as technical approaches to monitor response Discusses genetic reversions as a unique alteration and a new field of study Includes a chapter on upcoming and promising agents that are in the pre-clinical and early clinical space, to set the stage for future directions in the field

Cancer Cell Chemoresistance And Chemosensitization Book PDF
✏Book Title : Cancer Cell Chemoresistance and Chemosensitization
✏Author : Ajaikumar B. Kunnumakkara
✏Publisher : World Scientific
✏Release Date : 2018
✏Pages :
✏ISBN : 9789813208575
✏Available Language : English, Spanish, And French

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✏Cancer Cell Chemoresistance and Chemosensitization Book Summary :

Progress In Cancer Drug Resistance Research Book PDF
✏Book Title : Progress in Cancer Drug Resistance Research
✏Author : Robert A. Parsons
✏Publisher : Nova Publishers
✏Release Date : 2007
✏Pages : 223
✏ISBN : 1600218229
✏Available Language : English, Spanish, And French

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✏Progress in Cancer Drug Resistance Research Book Summary : One of the main causes of failure in the treatment of cancer is the development of drug resistance by the cancer cells. The design of cancer chemotherapy has become increasingly sophisticated, yet there is no cancer treatment that is 100 percent effective against disseminated cancer. Resistance to treatment with anticancer drugs results from a variety of factors including individual variations in patients and somatic cell genetic differences in tumours, even those from the same tissue of origin. Frequently resistance is intrinsic to the cancer, but as therapy becomes more and more effective, acquired resistance has also become common.The most common reason for acquisition of resistance to a broad range of anticancer drugs is expression of one or more energy-dependent transporters that detect and eject anti-cancer drugs from cells, but other mechanisms of resistance including insensitivity to drug-induced apoptosis and induction of drug-detoxifying mechanisms probably play an important role in acquired anticancer drug resistance. Studies on mechanisms of cancer drug resistance have yielded important information on how to circumvent this resistance to improve cancer chemotherapy and have implications for pharmacokinetics of many commonly used drugs.

Biological Mechanisms And The Advancing Approaches To Overcoming Cancer Drug Resistance Book PDF
✏Book Title : Biological Mechanisms and the Advancing Approaches to Overcoming Cancer Drug Resistance
✏Author : Andrew Freywald
✏Publisher : Academic Press
✏Release Date : 2020-12-04
✏Pages : 308
✏ISBN : 9780128213117
✏Available Language : English, Spanish, And French

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✏Biological Mechanisms and the Advancing Approaches to Overcoming Cancer Drug Resistance Book Summary : Biological Mechanisms and the Advancing Approaches to Overcoming Cancer Drug Resistance, Volume 12, discusses new approaches that are being undertaken to counteract tumor plasticity, understand and tackle the interactions with the microenvironment, and disrupt the rewiring of malignant cells or bypass biological mechanism of resistance by using targeted radionuclide therapies. This book provides a unique opportunity to the reader to understand the fundamental causes of drug resistance and how different approaches are applied. It is a one-stop-shop to understand why it is so difficult to treat cancer, and why only a very few patients respond to therapy and a significant portion develop resistance. Despite a rapid development of more effective anti-cancer drugs and combination therapies, cancer remains the leading cause of lethality in the developed world. The main reason for this is the ability of heterogeneous subpopulations of tumor cells interacting with constantly evolving tumor microenvironment to resist elimination and eventually, trigger cancer relapse. In this book, experts review current concepts explaining molecular and biological mechanisms of cancer drug resistance and discussing advancing approaches for overcoming these therapeutic challenges. Provides the most updated knowledge on the mechanisms of cancer drug resistance and the emerging therapeutic approaches reviewed by experts in the field Brings detailed analyses of most important recently reported developments related to drug resistance and their relevance to overcoming it in cancer patients Discusses in-depth molecular mechanisms and novel concepts of cancer resistance to conventional and advanced therapies

Cancer Drug Resistance Research Perspectives Book PDF
✏Book Title : Cancer Drug Resistance Research Perspectives
✏Author : Liman S. Torres
✏Publisher : Nova Publishers
✏Release Date : 2007
✏Pages : 223
✏ISBN : 1600215726
✏Available Language : English, Spanish, And French

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✏Cancer Drug Resistance Research Perspectives Book Summary : One of the main causes of failure in the treatment of cancer is the development of drug resistance by the cancer cells. The design of cancer chemotherapy has become increasingly sophisticated, yet there is no cancer treatment that is 100% effective against disseminated cancer. Resistance to treatment with anticancer drugs results from a variety of factors including individual variations in patients and somatic cell genetic differences in tumours, even those from the same tissue of origin. Frequently resistance is intrinsic to the cancer, but as therapy becomes more and more effective, acquired resistance has also become common. The most common reason for acquisition of resistance to a broad range of anticancer drugs is expression of one or more energy-dependent transporters that detect and eject anticancer drugs from cells, but other mechanisms of resistance including insensitivity to drug-induced apoptosis and induction of drug-detoxifying mechanisms probably play an important role in acquired anticancer drug resistance. Studies on mechanisms of cancer drug resistance have yielded important information about how to circumvent this resistance to improve cancer chemotherapy and have implications for pharmacokinetics of many commonly used drugs. This book presents new and important research in this field.

Drug Resistance In Colorectal Cancer Molecular Mechanisms And Therapeutic Strategies Book PDF
✏Book Title : Drug Resistance in Colorectal Cancer Molecular Mechanisms and Therapeutic Strategies
✏Author : Chi Hin Cho
✏Publisher : Academic Press
✏Release Date : 2020-05-24
✏Pages : 240
✏ISBN : 9780128199381
✏Available Language : English, Spanish, And French

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✏Drug Resistance in Colorectal Cancer Molecular Mechanisms and Therapeutic Strategies Book Summary : Drug Resistance in Colorectal Cancer: Molecular Mechanisms and Therapeutic Strategies, Volume Eight, summarizes the molecular mechanisms of drug resistance in colorectal cancer, along with the most up-to-date therapeutic strategies available. The book discusses reasons why colorectal tumors become refractory during the progression of the disease, but also explains how drug resistance occurs during chemotherapy. In addition, users will find the current therapeutic strategies used by clinicians in their practice in treating colorectal cancer. The combination of conventional anticancer drugs with chemotherapy-sensitizing agents plays a pivotal role in improving the outcome of colorectal cancer patients, in particular those with drug-resistant cancer cells. From a clinical point-of-view, the content of this book provides clinicians with updated therapeutic strategies for a better choice of drugs for drug-resistant colorectal cancer patients. It will be a valuable source for cancer researchers, oncologists and several members of biomedical field who are dedicated to better treat patients with colorectal cancer. Presents a systemic summary of molecular mechanisms for a quick and in-depth understanding Updates current trends in the field with pioneering information on drug resistance Encompasses both basic and clinical approaches for a better understanding of unsolved problems from a holistic point-of-view

Overcoming Drug Resistance In Gynecologic Cancers Book PDF
✏Book Title : Overcoming Drug Resistance in Gynecologic Cancers
✏Author :
✏Publisher : Academic Press
✏Release Date : 2021-05-15
✏Pages : 300
✏ISBN : 012824299X
✏Available Language : English, Spanish, And French

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✏Overcoming Drug Resistance in Gynecologic Cancers Book Summary : Overcoming Drug Resistance in Gynecologic Cancers provides up-to-date information related to important gynecologic cancers and focuses on mechanisms of drug resistance, genetics, signaling, immunology, health disparities, nanotechnology, economic considerations and financial impacts. The book covers not only drug resistance but also important means to reverse resistance both in the laboratory and clinic. The book discusses topics such as lifestyle, nutrition and risk of gynecologic cancers, the financial impact of drug resistance, chemosensitizing agents and targeted therapies in cervical, endometrial and ovarian cancer, immunotherapy to overcome drug resistance, and genetic polymorphisms in gynecologic cancers. Additionally, it discusses ethnic and racial health disparity perspectives and future developments in chemosensitizing activities to reverse drug resistance in gynecologic cancers. It is a valuable resource for cancer researchers, oncologists, clinicians and other biomedical field members who are interested in new approaches to improve chemotherapy outcome in patients with gynecologic cancers. Provides a comprehensive resource with all the details needed for readers to understand and follow information Encompasses schematics, diagrams and flow charts in all chapters to help readers easily follow critical information Presents tables and figures especially developed to summarize the information with appropriate statistical rigor and to show details of clinical specimens such as pathological, radiological characteristics, and/or laboratory biomarkers

📒Ovarian Cancer ✍ George Coukos

Ovarian Cancer Book PDF
✏Book Title : Ovarian Cancer
✏Author : George Coukos
✏Publisher : Springer Science & Business Media
✏Release Date : 2008-06-06
✏Pages : 308
✏ISBN : 9780387689692
✏Available Language : English, Spanish, And French

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✏Ovarian Cancer Book Summary : Aegean Conferences is an independent, nonprofit, educational organization directed and managed by the scientific community. The board is made up of nine researchers/scientists in various disciplines from Harvard, Brown, University of Pennsylvania, UCSD, Princeton, Biovista and the Foundation for Biomedical Research Academy of Athens. The board both invites and approves unsolicited proposals for Conferences in all fields of Science, Engineering, Arts, and Humanities. The purpose of the Conferences is to bring together individuals with common interests to examine the emerging and most advanced aspects of their particular field. The Symposium on Ovarian Cancer: State of the Art and Future Directions intends to bring together international experts interested in the development of novel diagnostic, prognostic and therapeutic tools for ovarian cancer. The meeting will function as a think tank where clinicians, translational and basic scientists, and parties from the biotechnology and pharmaceutical industry will get together to review recent advances in clinical research and translational science in ovarian cancer and define areas of future research opportunities and priorities.

Drug Resistance In Oncology Book PDF
✏Book Title : Drug Resistance in Oncology
✏Author : S. Bernal
✏Publisher : CRC Press
✏Release Date : 1997-08-21
✏Pages : 416
✏ISBN : 1420002090
✏Available Language : English, Spanish, And French

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✏Drug Resistance in Oncology Book Summary : This timely new reference integrates the latest clinical results and laboratory studies on the resistance of specific cancers to chemotherapeutic drugs-covering drug resistance in lung, breast, ovary, and colon cancer as well as hematological malignancies.

📒Ovarian Cancer 3 ✍ Frank Sharp

Ovarian Cancer 3 Book PDF
✏Book Title : Ovarian Cancer 3
✏Author : Frank Sharp
✏Publisher : Springer
✏Release Date : 2012-12-06
✏Pages : 390
✏ISBN : 9781475701364
✏Available Language : English, Spanish, And French

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✏Ovarian Cancer 3 Book Summary : The Helene Harris Memorial Trust has become recognized as providing one of the most important international fora for the presentation of research in ovarian cancer. Four biennial meetings have taken place, the most recent of which was held between May 11-14, 1993, in Toronto, Canada. This forum has grown in stature from its inception in 1987 and has brought together interdisciplinary clinical and scientific researchers from around the world who are endeavouring to perform 'cutting edge' studies in the field. The assembled group of presti gious investigators met on this occasion to present their data, to exchange ideas, and to arrange collaborations with the goal of developing new means of detection, treatment and cure of ovarian cancer. The incentive for the establishment of the Trust and its international forum was the prema ture loss through ovarian cancer of Helene Harris, the wife of Mr John Harris. Mr Harris and the Trustees looked for a meaningful way to honour the memory of Helene and to advance the noble cause of gaining an increase in the scientific knowledge of the subject. For those of us who spend most of our waking hours assisting patients and their families who are devastated by this disease, the Trust's generosity provides inspiration, hope and the opportunity for their practical application in a unique professional forum.

Drug Resistance In Cancer Therapy Book PDF
✏Book Title : Drug Resistance in Cancer Therapy
✏Author : Robert F. Ozols
✏Publisher : Springer Science & Business Media
✏Release Date : 2012-12-06
✏Pages : 210
✏ISBN : 9781461316015
✏Available Language : English, Spanish, And French

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✏Drug Resistance in Cancer Therapy Book Summary : Where do you begin to look for a recent, authoritative article on the diagnosis or management of a particular malignancy? The few general oncology textbooks are generally out of date. Single papers in specialized journals are informative but seldom comprehensive; these are more often preliminary reports on a very limited number of patients. Certain general journals frequently publish good in-depth reviews of cancer topics, and published symposium lectures are often the best overviews available. Unfor tunately, these reviews and supplements appear sporadically, and the reader can never be sure when a topic of special interest will be covered. Cancer Treatment and Research is a series of authoritative volumes that aim to meet this need. It is an attempt to establish a critical mass of oncology literature covering virtually all oncology topics, revised frequently to keep the coverage up to date, easily available on a single library shelf or by a single personal subscription. We have approached the problem in the following fashion: first, by dividing the oncology literature into specific subdivisions such as lung can cer, genitourinary cancer, and pediatric oncology; second, by asking emi nent authorities in each of these areas to edit a volume on the specific topic on an annual or biannual basis. Each topic and tumor type is covered in a volume appearing frequently and predictably, discussing current diagnosis, staging, markers, all forms of treatment modalities, basic biology, and more.

📒Gynecologic Oncology ✍ Robert F. Ozols

Gynecologic Oncology Book PDF
✏Book Title : Gynecologic Oncology
✏Author : Robert F. Ozols
✏Publisher : Taylor & Francis
✏Release Date : 1998
✏Pages : 387
✏ISBN : 0792380703
✏Available Language : English, Spanish, And French

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✏Gynecologic Oncology Book Summary : Text focusing primarily on ovarian cancer. Explores advances in cytoreductive surgery, problems in screening, new drugs, chemotherapy, hereditary basis for gynecologic malignancies, molecular genetics, molecular biology, and new biologic therapies. For researchers and pathologists, surgeons, chemotherapists, and practitioners.

Drug Resistance In Cancer Cells Book PDF
✏Book Title : Drug Resistance in Cancer Cells
✏Author : Kapil Mehta
✏Publisher : Springer Science & Business Media
✏Release Date : 2009-06-12
✏Pages : 363
✏ISBN : 0387894454
✏Available Language : English, Spanish, And French

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✏Drug Resistance in Cancer Cells Book Summary : It was estimated that in 2008, 1,437,180 patients would receive a new cancer diagnosisand 565,650individualswould die of cancer (Jemal et al. 2008).Since the vast majority of patients dying of cancer will have had anticancer therapy, both c- ventional chemotherapy and novel targeted therapy, it can be concluded that these patients are dying with drug resistant cancer. The term multidrug resistance is also apt – in that these patients die after having undergone multiple rounds of different and structurally unrelated cancer therapies. However, for some, the concept of m- tidrug resistance is a worn out idea, stemming from disappointment with the drug resistancereversalstrategiesthatwerecarriedoutinthe1990susingpumpinhibitors to block drug resistance mediated by P-glycoprotein, product of the MDR-1 gene. However, if one takes the larger de?nition – multidrug resistance as simultaneous resistance to multiple structurally unrelated anticancer therapies – its existence c- not be denied. The purpose of this book is to explore new concepts related to drug resistance in cancer, including resistance to the new molecularly targeted agents. Perhaps new terminology is needed for resistance that occurs following therapy with the targeted agents: Novel Targeted Agent Resistance (NTR). Alternatively, we can return to the original de?nition of multidrug resistance as simply the res- tance to multipleagents that occurs in the course of normalcancer progression.This resistance is likely to be mediated by many factors.

Advances In Epithelial Ovarian Cancer Model Systems Microenvironmental Influences Therapy And Origins Book PDF
✏Book Title : Advances in Epithelial Ovarian Cancer Model Systems Microenvironmental Influences Therapy and Origins
✏Author : Viive Maarika Howell
✏Publisher : Frontiers Media SA
✏Release Date : 2016-02-03
✏Pages :
✏ISBN : 9782889197699
✏Available Language : English, Spanish, And French

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✏Advances in Epithelial Ovarian Cancer Model Systems Microenvironmental Influences Therapy and Origins Book Summary : This eBook provides a compendium of the current state-of-the-art in research tools for, and understanding of, the critical research areas in epithelial ovarian cancer (EOC) with a strong emphasis on (HG-SOC). Research areas covered include therapy response and development, microenvironmental influences and the etiology and progression of EOC. Ten articles detail established and novel in vivo and in vitro model systems. These include primary and immortalized cell culture in 2D and 3D as well as genetically engineered, transgenic, spontaneous, syngeneic, classical xenograft and patient derived xenograft mouse models. The generation of genetically engineered mouse models of HG-SOC has been a major dilemma as models with the oncogenic aberrations common in the human malignancy do not accurately recapitulate HG-SOC. Conversely, commonly used HG-SOC cell lines have been found to not harbor the expected genetic changes. These issues as well as the rapid acceptance of patient derived xenograft models are reviewed. Five articles discuss different aspects of the tumor microenvironment including its role in therapy resistance, disease progression and metastasis. Mutation of BRCA1/2 continues to be the best defined risk factor for HG-SOC. Three articles discuss BRCA-loss in the context of disease development, targeted therapies and changes in preventative measures proposed for mutation carriers in light of the recent advances in knowledge regarding the origins of this malignancy. An image of HG-SOC with reduced BRCA1 expression is featured on the cover (image by VM Howell). A major clinical issue for patients with HG-SOC is the development of therapy resistance. Five articles focus on therapy resistance and different ways to overcome resistance. Overall, this eBook is an outstanding resource to aid researchers design their programs of research and determine the most appropriate and up-to-date EOC model systems to address their research questions.

📒Ovarian Cancer ✍ Robert F. Ozols

Ovarian Cancer Book PDF
✏Book Title : Ovarian Cancer
✏Author : Robert F. Ozols
✏Publisher : PMPH-USA
✏Release Date : 2003
✏Pages : 246
✏ISBN : 1550090968
✏Available Language : English, Spanish, And French

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✏Ovarian Cancer Book Summary : "Featuring more than 300 illustrations, the text covers pathology, biology, epidemiology, genetics, and screening through surgical management, the latest in chemotherapeutic regimens, and finally, palliative care"--P. [4] of cover.

📒Cancer Drug Resistance ✍ Thomas C. Hall

Cancer Drug Resistance Book PDF
✏Book Title : Cancer Drug Resistance
✏Author : Thomas C. Hall
✏Publisher :
✏Release Date : 1986
✏Pages : 235
✏ISBN : UOM:39015011479253
✏Available Language : English, Spanish, And French

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✏Cancer Drug Resistance Book Summary :

Ovarian Cancer New Insights For The Healthcare Professional 2011 Edition Book PDF
✏Book Title : Ovarian Cancer New Insights for the Healthcare Professional 2011 Edition
✏Author :
✏Publisher : ScholarlyEditions
✏Release Date : 2012-01-09
✏Pages : 274
✏ISBN : 9781464900600
✏Available Language : English, Spanish, And French

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✏Ovarian Cancer New Insights for the Healthcare Professional 2011 Edition Book Summary : Ovarian Cancer: New Insights for the Healthcare Professional: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Ovarian Cancer. The editors have built Ovarian Cancer: New Insights for the Healthcare Professional: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Ovarian Cancer in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Ovarian Cancer: New Insights for the Healthcare Professional: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Intraperitoneal Therapy For Ovarian Cancer Book PDF
✏Book Title : Intraperitoneal Therapy for Ovarian Cancer
✏Author : David Alberts
✏Publisher : Springer Science & Business Media
✏Release Date : 2010-08-24
✏Pages : 153
✏ISBN : 3642121306
✏Available Language : English, Spanish, And French

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✏Intraperitoneal Therapy for Ovarian Cancer Book Summary : Intraperitoneal chemotherapy is increasingly being used as first-line treatment for ovarian cancer. Nevertheless, it is difficult for the oncologist to find a definitive text that documents both the fundamental methods required to optimize therapy and the up-to-date results of phase I, II, and III clinical trials. With this in mind, the editors of Intraperitoneal Chemotherapy have assembled a team of highly experienced clinicians and researchers to cover every aspect of the subject. The topics addressed include treatment principles, patient, drug, and catheter selection, administration guidelines, the role of hyperthermia, supportive care requirements, novel drugs, and the most recent results of clinical trials. This book will be an invaluable source of information for both practicing clinical oncologists and oncologists in training.

Selected Topics In Obstetrics And Gynaecology 4 For Postgraudate And Practitioners Book PDF
✏Book Title : Selected Topics in Obstetrics and Gynaecology 4 For Postgraudate and Practitioners
✏Author : Daftary & Desai
✏Publisher : BI Publications Pvt Ltd
✏Release Date : 2008
✏Pages : 322
✏ISBN : 8172253060
✏Available Language : English, Spanish, And French

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✏Selected Topics in Obstetrics and Gynaecology 4 For Postgraudate and Practitioners Book Summary :

📒Pipac ✍ Marc A. Reymond

Pipac Book PDF
✏Book Title : PIPAC
✏Author : Marc A. Reymond
✏Publisher : Walter de Gruyter GmbH & Co KG
✏Release Date : 2014-10-14
✏Pages : 252
✏ISBN : 9783110366617
✏Available Language : English, Spanish, And French

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✏PIPAC Book Summary : Peritoneal dissemination is a common route of cancer metastasis. The benefit of administering chemotherapy directly into the peritoneal cavity is supported by preclinical and pharmacokinetic data. In comparison to intravenous (IV) treatment, intraperitoneal (IP) administration results in a several-fold increase in drug concentration within the abdominal cavity. There is now growing evidence from clinical studies showing a survival advantage for IP chemotherapy in various tumor typies, including ovarian, gastric and colorectal cancer. However, while the use of IP chemotherapy is slowly gaining acceptance, it is not universal, largely due to the greater toxicity associated with this approach. Moreover, efficacy of IP chemotherapy is limited by poor distribution within the abdominal cavity and by poor tissue penetration. A new way of IP chemotherapy is the application of cytotoxics in form of a pressurized aerosol into the abdominal of thoracic cavity. Pressurized intraperitoneal aerosol chemotherapy (PIPAC) is applied through laparoscopic access using two balloon trocars in an operating room equipped with laminar air-flow. In a first step,a normothermic capnoperitoneum is established with a pressure of 12 mmHg. A cytotoxic solution (about 10% of a normal systemic dose) is nebulized with a micropump into the abdominal cavity, and maintained for 30 min. The aerosol is then removed through a closed suction system. Applying an aerosol in the peritoneal cavity allows a homogeneous distribution of the chemotherapeutic agent within the abdomen. Furthermore, an artificial pressure gradient is generated that overcomes tumoral interstitial fluid pressure, an obstacle in cancer therapy. This results in a higher local drug concentration compared to conventional IP or IV chemotherapy. At the same time the plasma concentration of the chemotherapeutic agent remains low. In first clinical studies with limited number of patients in ovarian, gastric and colorectal cancer, as well as peritoneal mesothelioma, PIPAC has obtained encouraging tumor response rates and survival, with a low-side effects profile. Larger clinical trials are currently ongoing to examine if these data can be reproduced and extrapolated to other situations.

Current Applications For Overcoming Resistance To Targeted Therapies Book PDF
✏Book Title : Current Applications for Overcoming Resistance to Targeted Therapies
✏Author : Myron R. Szewczuk
✏Publisher : Springer
✏Release Date : 2019-07-15
✏Pages : 320
✏ISBN : 9783030214777
✏Available Language : English, Spanish, And French

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✏Current Applications for Overcoming Resistance to Targeted Therapies Book Summary : Targeted therapies were initially developed to exploit the upregulation and dependence on key oncogenic pathways critical to cancer progression. Additionally, they also presented as a method to overcome chemoresistance by supplementing conventional therapeutic regimens with targeted therapies. However, the development of resistance to these combinatorial approaches has led to the reassessment of currently available therapeutic options to overcome resistance to targeted therapy. This book aims to provide an update on the advancements in the therapeutic arms race between cancer, clinicians and scientists alike to overcome resistance to targeted therapies. Subject experts provide a comprehensive overview of the challenges and solutions to resistance to several conventional targeted therapies in addition to providing a discussion on broad topics including targeting components of the tumor microenvironment, emerging therapeutic options, and novel areas to be explored concerning nanotechnology and the epigenome.

Selected Topics In Obstetrics And Gynaecology 3 For Postgraudate And Practitioners Book PDF
✏Book Title : Selected Topics in Obstetrics and Gynaecology 3 For Postgraudate and Practitioners
✏Author : Shirish N Daftary
✏Publisher : BI Publications Pvt Ltd
✏Release Date : 2007
✏Pages : 304
✏ISBN : 8172252498
✏Available Language : English, Spanish, And French

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✏Selected Topics in Obstetrics and Gynaecology 3 For Postgraudate and Practitioners Book Summary : This is the third issue of the popular series Selected Topics in Obstetrics and Gynaecology. The objective of the series is to present updates and reviews of the current trends in selected and emerging areas of obstetrics and gynaecology, including Indian experience in the subject under review.Selection of topics provides a focus on a range of interesting subjects in a stimulating and concise manner. These review articles are aimed at providing quick updates on the subjects to equip the postgraduate students with contemporary knowledge, and to help practitioners to adopt the recent trends in patient care.

📒Chemosensitivity ✍ Rosalyn D. Blumenthal

Chemosensitivity Book PDF
✏Book Title : Chemosensitivity
✏Author : Rosalyn D. Blumenthal
✏Publisher : Springer Science & Business Media
✏Release Date : 2005
✏Pages : 328
✏ISBN : 9781592598694
✏Available Language : English, Spanish, And French

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✏Chemosensitivity Book Summary : Volume 1 provides a panel of 16 in vitro measures of chemosensitivity in adherent and non-adherent cells for single agents and combinations of agents. In addition to immunohistochemical and imaging approaches, these assays include clonogenic, colorimetric, fluorometric, and physiological assays.

Principles Of Cancer Biotherapy Book PDF
✏Book Title : Principles of Cancer Biotherapy
✏Author : Robert K. Oldham
✏Publisher : Springer Science & Business Media
✏Release Date : 2009-08-29
✏Pages : 742
✏ISBN : 9048122899
✏Available Language : English, Spanish, And French

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✏Principles of Cancer Biotherapy Book Summary : At the time of the first edition of Principles of Cancer Biotherapy in 1987, this book represented the first comprehensive textbook on biological therapy. In 1991, when the second edition was published, there was still some doubt on the part of many oncologists and cancer researchers as to the therapeutic value of these new approaches. By 2003 and the fourth edition, it was generally agreed that biopharmaceuticals were producing major opportunities for new cancer therapies. Cancer biotherapy has now truly matured into the fourth modality of cancer treatment. This fifth revised edition describes the tremendous progress that has been made in recent years using biologicals in cancer treatment. This book summarizes an evolving science and a rapidly changing medical practice in biotherapy. In this new millennium, it is now possible to envision a much more diversified system of cancer research and treatment that will afford greater opportunities for a patient’s personalized cancer treatment. This was first envisioned in the 1987 initial edition of this textbook and is now a “new” and popular approach to cancer treatment. Some forms of cancer biotherapy use the strategy of tumor stabilization and control through continued biological therapy, akin to the use of insulin in the treatment of diabetes. This textbook illustrates new methods of thinking and new strategies for control of cancer. It is always difficult to move from past dogma to future opportunity, but this fifth edition of Principles of Cancer Biotherapy illustrates why it is so important to the patients for researchers and clinicians to explore and quickly apply these new opportunities in cancer biotherapy.

📒Fast Facts Ovarian Cancer ✍ Christina Fotopoulou

Fast Facts Ovarian Cancer Book PDF
✏Book Title : Fast Facts Ovarian Cancer
✏Author : Christina Fotopoulou
✏Publisher : Karger Medical and Scientific Publishers
✏Release Date : 2017-05-09
✏Pages : 102
✏ISBN : 9781910797433
✏Available Language : English, Spanish, And French

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✏Fast Facts Ovarian Cancer Book Summary : When it comes to detecting, diagnosing and treating women who have, or are suspected of having, ovarian cancer, there are significant opportunities for well-informed healthcare professionals to intervene in a meaningful way. 'Fast Facts: Ovarian Cancer' examines the areas that will have the biggest effect in clinical practice, including: • the evidence for and against screening • the valuable role of genetic testing in identifying at-risk women • if and when to operate • strategies to overcome platinum resistance • the impact of targeted therapies. From the tools that will help establish a swift diagnosis to the risks and benefits of palliative salvage surgery, this refreshingly readable resource captures the key knowledge that every busy healthcare professional needs in order to make better health decisions for patients with ovarian cancer. Contents: • Epidemiology and prevention • Pathophysiology and classification • Genetic testing • Diagnosis, staging and grading • Surgery • Chemotherapy • Recurrent ovarian cancer • Targeted therapies • Non-epithelial ovarian cancers • Follow-up and palliative surgery • Useful resources

Cancer Chemotherapy Book PDF
✏Book Title : Cancer Chemotherapy
✏Author :
✏Publisher :
✏Release Date : 1991
✏Pages :
✏ISBN : UOM:39015020587450
✏Available Language : English, Spanish, And French

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✏Cancer Chemotherapy Book Summary :

📒Cancer Chemotherapy 1 ✍ Franco M. Muggia

Cancer Chemotherapy 1 Book PDF
✏Book Title : Cancer Chemotherapy 1
✏Author : Franco M. Muggia
✏Publisher : Springer Science & Business Media
✏Release Date : 2012-12-06
✏Pages : 346
✏ISBN : 9781461339038
✏Available Language : English, Spanish, And French

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✏Cancer Chemotherapy 1 Book Summary : Where do you begin to look for a recent, authoritative article on the diagnosis or management ofa particular malignancy? The few general onco logy textbooks are generally out of date. Single papers in specialized journals are informative but seldom comprehensive; these are more often prelimi nary reports on a very limited number of patients. Certain general journals frequently publish good indepth reviews of cancer topics, and published symposium lectures are often the best overviews available. Unfortunately, these reviews and supplements appear sporadically, and the reader can nev er be sure when a topic of special interest will be covered. Cancer Treatment and Research is a series of authoritative volumes which aim to meet this need. It is an attempt to establish a critical mass of oncology literature covering virtually all oncology topics, revised frequently to keep the coverage up to date, easily available on a single library shelf or by a single personal subscription. We have approached the problem in the following fashion. First, by div iding the oncology literature into specific subdivisions such as lung cancer, genitourinary cancer, pediatric oncology, etc. Second, by asking eminent authorities in each of these areas to edit a volume on the specific topic on an annual or biannual basis. Each topic and tumor type is covered in a volume appearing frequently and predictably, discussing current diagnosis, staging, markers, all forms of treatment modalities, basic biology, and more.

📒Combination Cancer Therapy ✍ Gary K. Schwartz

Combination Cancer Therapy Book PDF
✏Book Title : Combination Cancer Therapy
✏Author : Gary K. Schwartz
✏Publisher : Springer Science & Business Media
✏Release Date : 2007-10-27
✏Pages : 284
✏ISBN : 9781592598649
✏Available Language : English, Spanish, And French

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✏Combination Cancer Therapy Book Summary : Expert physician-scientists and clinicians review those combinations of novel target agents classic chemotherapies that hold the most promise for the future of medical oncology, and detail their optimal sequence, pharmacokinetic interactions, and interaction with downstream cellular signals. The combinations run the gamut of targeted therapies against cell surface receptors (EGF-R and HER2), the cell cycle (the CDKs), signal transduction events (PKC and NF-kB), apoptosis (bcl-2), as well as focused therapies in ovarian cancer, hematologic diseases, and breast cancer. The authors emphasize novel translational approaches that are rapidly moving from the laboratory bench top to the patient's bedside for the future treatments in cancer therapy.

Anticancer Research Book PDF
✏Book Title : Anticancer Research
✏Author :
✏Publisher :
✏Release Date : 2010
✏Pages :
✏ISBN : UCSD:31822036999886
✏Available Language : English, Spanish, And French

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✏Anticancer Research Book Summary :

Pharmacology And Medicines Management For Nurses E Book Book PDF
✏Book Title : Pharmacology and Medicines Management for Nurses E Book
✏Author : George Downie
✏Publisher : Elsevier Health Sciences
✏Release Date : 2007-12-28
✏Pages : 576
✏ISBN : 9780702033339
✏Available Language : English, Spanish, And French

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✏Pharmacology and Medicines Management for Nurses E Book Book Summary : This title is directed primarily towards health care professionals outside of the United States. An understanding of medicines and their effects on patients remains a crucial area of nursing knowledge. This book provides a thorough foundation upon which nurses can build their clinical experience to achieve competence. It not only provides information on the actions of drugs on the body but also gives clear guidance on the practical aspects of medicines management in both hospital and community. Organisation of the text broadly follows the British National Formulary for ease of use. Management of medicines linked to their therapeutic use Medicine administration linked with relevant care of patients where possible Basic principles of clinical pharmacology underpin the therapeutic chapters A chapter on the role of patients and carers is included All content revised in the light of changes in drug therapy, clinical practice and medicines management including nurse prescribing Key objectives for each chapter Self-assessment exercises with answers More detail relating to palliative care; nurse prescribing A new section on Intensive Therapy Totally redesigned in two colours with improved design and page layout, and better illustrations