Organ on a chip

• Author : Julia Hoeng,David Bovard,Manuel Peitsch
• Publisher : Academic Press
• Release : 09 November 2019

Organ-on-a-Chip: Engineered Microenvironments for Safety and Efficacy Testing contains chapters from world-leading researchers in the field of organ on a chip development and applications, with perspectives from life sciences, medicine, physiology and engineering. The book contains an overview of the field, with sections covering the major organ systems and currently available technologies, platforms and methods. As readers may also be interested in creating biochips, materials and engineering best practice, these topics are also described. Users will learn about the limitations

• Author : Dr.Hakim Saboowala
• Publisher : Dr.Hakim Saboowala
• Release : 07 January 2020

The capability of traditional platforms, such as well plate, does not match researchers’ demands for precise and creative experiments any more. Direct detection and analysis of biomolecules and cells in physiological microenvironment is urgently needed for fast evaluation of biology and pharmacy. The past several years have witnessed remarkable development opportunities in vitro organs and tissues models with multiple functions based on microfluidic devices, termed as “organ-on-a-chip”. It is a promising technology in rebuilding physiological functions of tissues and organs,

• Author : Shi-Cong Tao,Shang-Chun Guo,Wei Seong Toh,Nuno M. Neves,Owen Gareth Davies
• Publisher : Frontiers Media SA
• Release : 11 January 2022

Existing culture systems have a limited ability to reproduce the complicated and dynamic microenvironment of a functioning organ. To solve the issues of conventional culture techniques, multidisciplinary researchers, involving medical doctors, stem cell and developmental biology experts, engineers and physical scientists, have emerged to innovate methods and devices. A microfluidic organ-on-a-chip (μOOC) is a cell culture device, based on microfluidic technology, which contains continuously perfused chambers with cells to simulate organ-level physiology/pathology. The μOOC is not to build a

• Author : Julia Hoeng,David Bovard,Manuel Peitsch
• Publisher : Academic Press
• Release : 01 November 2019

Organ on a Chip: Convergence of Advanced Materials, Cells, and Microscale Technologies contains chapters from world-leading researchers in the field of organ on a chip development and applications, with perspectives from life sciences, medicine, physiology and engineering. The book contains an overview of the field, with sections covering the major organ systems and currently available technologies, platforms and methods. As readers may also be interested in creating biochips, materials and engineering best practice, these topics are also described. Users will

• Author : Anonim
• Publisher : Unknown
• Release : 18 May 2022

Organ-on-a-chip is a microchip covered with live human cells that simulate the structures and functions of full-size organs and organ systems.

• Author : Qasem Ramadan,Massimo Alberti,Martin Dufva,Yi-Chung Tung
• Publisher : Frontiers Media SA
• Release : 16 October 2019

Recent developments in microfluidics have demonstrated enormous potential of microscale cell culture for biology studies and recognized as instrumental in performing rapid and efficient experiments on small-sample volumes. Microfluidic-based cell culture is an area of research that keeps growing and gaining importance as a prominent technology, able to link scientific disciplines with industrial and clinical applications. In particular, organotypic cell culture and its integration in microfluidic devices would enable the realization of “in vivo-like” cell microenvironment within systems that are

• Author : Jonas Christoffersson
• Publisher : Linköping University Electronic Press
• Release : 22 January 2019

Organs-on-chips are dynamic cell culture devices created with the intention to mimic organ function in vitro. Their purpose is to assess the toxicity and efficacy of drugs and, as early as possible in the pharmaceutical development process, predict the outcome of clinical trials. The aim of this thesis is to explain and discuss these cell culture devices from a design perspective and to experimentally exemplify some of the specific functions that characterize organs-on-chips. The cells in our body reside in

• Author : Yu-suke Torisawa,Yi-Chung Tung
• Publisher : MDPI
• Release : 27 May 2020

Recent advances in microsystems technology and cell culture techniques have led to the development of organ-on-chip microdevices that produce tissue-level functionality, not possible with conventional culture models, by recapitulating natural tissue architecture and microenvironmental cues within microfluidic devices. Since the physiological microenvironments in living systems are mostly microfluidic in nature, the use of microfluidic devices facilitates engineering cellular microenvironments; the microfluidic devices allow for control of local chemical gradients and dynamic mechanical forces, which play important roles in cellular viability

• Author : Jeong-Yeol Yoon
• Publisher : Springer Nature
• Release : 18 May 2022

• Author : James F. Leary
• Publisher : Cambridge University Press
• Release : 31 March 2022

A complete introduction to nanomedicine, grounded in real-world examples, and including over 200 thought-provoking self-study questions.

• Author : Xiujun James Li,Chaoyong Yang,Paul C. H. Li
• Publisher : Newnes
• Release : 19 September 2021

Multidisciplinary Microfluidic and Nanofluidic Lab-on-a-Chip: Principles and Applications provides chemists, biophysicists, engineers, life scientists, biotechnologists, and pharmaceutical scientists with the principles behind the design, manufacture, and testing of life sciences microfluidic systems. This book serves as a reference for technologies and applications in multidisciplinary areas, with an emphasis on quickly developing or new emerging areas, including digital microfluidics, nanofluidics, papers-based microfluidics, and cell biology. The book offers practical guidance on how to design, analyze, fabricate, and test microfluidic devices and

• Author : Hanjoong Jo,Ho-Wook Jun,Jennifer Shin,SangHoon Lee
• Publisher : Springer
• Release : 23 July 2015

This book provides readers with an integrative overview of the latest research and developments in the broad field of biomedical engineering. Each of the chapters offers a timely review written by leading biomedical engineers and aims at showing how the convergence of scientific and engineering fields with medicine has created a new basis for practically solving problems concerning human health, wellbeing and disease. While some of the latest frontiers of biomedicine, such as neuroscience and regenerative medicine, are becoming increasingly

• Author : Florentina Matei,Daniela Zirra
• Publisher : Springer
• Release : 16 August 2019

Primarily intended for biotechnology graduates, this handbook provides an overview of the requirements, opportunities and drawbacks of Biotech Entrepreneurship, while also presenting valuable training materials tailored to the industrial and market reality in the European Biotech Business. Potential investors and business consultants will find essential information on the benefits and potential risks involved in supporting biotech businesses. Further, the book addresses a broad range of Biotechnology fields, e.g. food biotech, industrial biotech, bioinformatics, animal and human health. Readers will

• Author : Josue Sznitman,Claus-Michael Lehr,Leslie Yeo
• Publisher : Frontiers Media SA
• Release : 28 December 2021

• Author : Anonim
• Publisher : Academic Press
• Release : 01 February 2022

Micro/Nanofluidics and Lab-on-Chip Based Emerging Technologies for Biomedical and Translational Research Applications - Part B, Volume 187 represents the collation of chapters written by eminent scientists worldwide. Chapters in this new release include Design and fabrication of microfluidics devices for molecular biology applications, Micro/Nanofluidics devices for drug delivery, From organ-on-chip to body-on-chip: the next generation of microfluidics platforms for in vitro drug toxicity testing, Micro/Nanofluidics for high throughput drug screening, Design, fabrication and assembly of lab-on-a-chip and its