Oral Delivery of Insulin

Produk Detail:
  • Author : T.A. Sonia
  • Publisher : Elsevier
  • Pages : 290 pages
  • ISBN : 1908818689
  • Rating : /5 from reviews
CLICK HERE TO GET THIS BOOK >>>Oral Delivery of Insulin

Download or Read online Oral Delivery of Insulin full in PDF, ePub and kindle. this book written by T.A. Sonia and published by Elsevier which was released on 11 December 2014 with total page 290 pages. We cannot guarantee that Oral Delivery of Insulin book is available in the library, click Get Book button and read full online book in your kindle, tablet, IPAD, PC or mobile whenever and wherever You Like. Diabetes Mellitus, a syndrome of disordered metabolism, characterised by abnormal elevation in blood glucose level, has become a life-threatening condition for many people. Current means of therapy for Diabetes Mellitus do not mimic the normal physiological pattern of insulin release. Oral delivery is the preferred route of administration due to its non-invasive nature. Oral delivery of insulin presents an overview of Diabetes Mellitus, and discusses the strategies and techniques adopted for oral delivery of insulin. This title begins with an introductory chapter on symptoms, complications and therapy for Diabetes Mellitus. Subsequent chapters cover the various routes for administering insulin; the challenges and strategies of oral delivery; experimental techniques in the development of an oral insulin carrier; lipids; inorganic nanoparticles and polymers in oral insulin delivery; and a summary and presentation of future perspectives on oral delivery of insulin. Presents an overview of Diabetes Mellitus Includes a discussion of various strategies and techniques adopted for oral delivery of insulin Presents an update of research in the field

Oral Delivery of Insulin

Oral Delivery of Insulin
  • Author : T.A. Sonia,Chandra P. Sharma
  • Publisher : Elsevier
  • Release : 11 December 2014
GET THIS BOOK Oral Delivery of Insulin

Diabetes Mellitus, a syndrome of disordered metabolism, characterised by abnormal elevation in blood glucose level, has become a life-threatening condition for many people. Current means of therapy for Diabetes Mellitus do not mimic the normal physiological pattern of insulin release. Oral delivery is the preferred route of administration due to its non-invasive nature. Oral delivery of insulin presents an overview of Diabetes Mellitus, and discusses the strategies and techniques adopted for oral delivery of insulin. This title begins with an

Development of Nanoparticles for Oral Delivery of Insulin

Development of Nanoparticles for Oral Delivery of Insulin
  • Author : Sunandini Chopra
  • Publisher : Unknown
  • Release : 23 October 2021
GET THIS BOOK Development of Nanoparticles for Oral Delivery of Insulin

Parenteral administration remains the mainstay of drug administration for protein therapeutics. However, for diseases that require frequent drug dose over long periods of time, injections can result in patient incompliance and poor treatment outcomes. For such diseases, oral drug delivery is the most non-invasive and patient-compliant method of drug administration. Although oral delivery of many small molecule drugs is routine, oral delivery of protein drugs - e.g. insulin presents several challenges including oral bioavailability of the protein therapeutic because

Recent Advances in Novel Drug Carrier Systems

Recent Advances in Novel Drug Carrier Systems
  • Author : Ali Demir Sezer
  • Publisher : IntechOpen
  • Release : 31 October 2012
GET THIS BOOK Recent Advances in Novel Drug Carrier Systems

This contribution book collects reviews and original articles from eminent experts working in the interdisciplinary arena of novel drug delivery systems and their uses. From their direct and recent experience, the readers can achieve a wide vision on the new and ongoing potentialities of different drug delivery systems. Since the advent of analytical techniques and capabilities to measure particle sizes in nanometer ranges, there has been tremendous interest in the use of nanoparticles for more efficient methods of drug delivery.

The Modification of Insulin to Enhance Oral Delivery Systems

The Modification of Insulin to Enhance Oral Delivery Systems
  • Author : Melissa Ann Kanzelberger
  • Publisher : Unknown
  • Release : 23 October 2021
GET THIS BOOK The Modification of Insulin to Enhance Oral Delivery Systems

While a number of PEGylated proteins have been studied for injectable applications and reviewers have used this data to speculate possible oral delivery improvements, a detailed investigation of PEGylated insulin for oral delivery and the development of an optimized pH-sensitive carrier for PEGylated insulin conjugates had yet to be accomplished. In order to proceed with oral delivery study, improvements in yield, with respect to previous PEGylation methods were necessary to enable the completion of high throughput drug delivery studies. Subsequently,

Drug Delivery

Drug Delivery
  • Author : Yitzhak Rosen,Pablo Gurman,Noel Elman
  • Publisher : CRC Press
  • Release : 19 September 2017
GET THIS BOOK Drug Delivery

Integrating the clinical and engineering aspects of drug delivery, this book offers a much needed comprehensive overview and patient-oriented approach for enhanced drug delivery optimization and advancement. Starting with an introduction to the subject and pharmacokinetics, it explores advances for such topics as oral, gastroretentive, intravitreal, and intrathecal drug delivery, as well as insulin delivery, gene delivery, and biomaterials-based delivery systems. It also describes drug delivery in cancer, cardiac, infectious diseases, airway diseases, and obstetrics and gynecology applications. Examining special

Low Cost Production of Proinsulin in Tobacco and Lettuce Chloroplasts for Injectable Or Oral Delivery of Functional Insulin and C peptide

Low Cost Production of Proinsulin in Tobacco and Lettuce Chloroplasts for Injectable Or Oral Delivery of Functional Insulin and C peptide
  • Author : Diane Dara Burberry
  • Publisher : Unknown
  • Release : 23 October 2021
GET THIS BOOK Low Cost Production of Proinsulin in Tobacco and Lettuce Chloroplasts for Injectable Or Oral Delivery of Functional Insulin and C peptide

Current treatment for type I diabetes includes delivery of insulin via injection or pump, which is highly invasive and expensive. The production of chloroplast-derived proinsulin should reduce cost and facilitate oral delivery. Therefore, tobacco and lettuce chloroplasts were transformed with the cholera toxin B subunit fused with human proinsulin (A, B, and C peptides) containing three furin cleavage sites (CTB-PFx3). Transplastomic lines were confirmed for site-specific integration of transgene and homoplasmy. Old tobacco leaves accumulated proinsulin up to 47% of total