NMR Spectroscopy in Pharmaceutical Analysis

Produk Detail:
  • Author : Iwona Wawer
  • Publisher : Elsevier
  • Pages : 528 pages
  • ISBN : 008095152X
  • Rating : 5/5 from 1 reviews
CLICK HERE TO GET THIS BOOK >>>NMR Spectroscopy in Pharmaceutical Analysis

Download or Read online NMR Spectroscopy in Pharmaceutical Analysis full in PDF, ePub and kindle. this book written by Iwona Wawer and published by Elsevier which was released on 07 July 2017 with total page 528 pages. We cannot guarantee that NMR Spectroscopy in Pharmaceutical Analysis book is available in the library, click Get Book button and read full online book in your kindle, tablet, IPAD, PC or mobile whenever and wherever You Like. For almost a decade, quantitative NMR spectroscopy (qNMR) has been established as valuable tool in drug analysis. In all disciplines, i. e. drug identification, impurity profiling and assay, qNMR can be utilized. Separation techniques such as high performance liquid chromatography, gas chromatography, super fluid chromatography and capillary electrophoresis techniques, govern the purity evaluation of drugs. However, these techniques are not always able to solve the analytical problems often resulting in insufficient methods. Nevertheless such methods find their way into international pharmacopoeias. Thus, the aim of the book is to describe the possibilities of qNMR in pharmaceutical analysis. Beside the introduction to the physical fundamentals and techniques the principles of the application in drug analysis are described: quality evaluation of drugs, polymer characterization, natural products and corresponding reference compounds, metabolism, and solid phase NMR spectroscopy for the characterization drug substances, e.g. the water content, polymorphism, and drug formulations, e.g. tablets, powders. This part is accompanied by more special chapters dealing with representative examples. They give more detailed information by means of concrete examples. Combines theory, techniques, and concrete applications—all of which closely resemble the laboratory experience Considers international pharmacopoeias, addressing the concern for licensing Features the work of academics and researchers, appealing to a broad readership

NMR Spectroscopy in Pharmaceutical Analysis

NMR Spectroscopy in Pharmaceutical Analysis
  • Author : Iwona Wawer,Bernd Diehl
  • Publisher : Elsevier
  • Release : 07 July 2017
GET THIS BOOK NMR Spectroscopy in Pharmaceutical Analysis

For almost a decade, quantitative NMR spectroscopy (qNMR) has been established as valuable tool in drug analysis. In all disciplines, i. e. drug identification, impurity profiling and assay, qNMR can be utilized. Separation techniques such as high performance liquid chromatography, gas chromatography, super fluid chromatography and capillary electrophoresis techniques, govern the purity evaluation of drugs. However, these techniques are not always able to solve the analytical problems often resulting in insufficient methods. Nevertheless such methods find their way into international

NMR Spectroscopy in Drug Development and Analysis

NMR Spectroscopy in Drug Development and Analysis
  • Author : Ulrike Holzgrabe,Iwona Wawer,Bernd Diehl
  • Publisher : John Wiley & Sons
  • Release : 11 July 2008
GET THIS BOOK NMR Spectroscopy in Drug Development and Analysis

Since the development of the NMR spectrometer in the 1950s, NMR spectra have been widely used for the elucidation of the 2D structure of newly synthesized and natural compounds. In the 1980s, the high-resolution NMR spectrometer (> 300 Mhz) and 2D experiments were introduced, which opens up the possibility to determine the 3D structure of large molecules, especially biomolecules. However, NMR spectroscopy has been rarely applied to drug analysis. This book illustrates the power and versatility of NMR spectroscopy in the determination

Pharmaceutical Analysis

Pharmaceutical Analysis
  • Author : David C Lee,Michael L. Webb
  • Publisher : John Wiley & Sons
  • Release : 12 February 2009
GET THIS BOOK Pharmaceutical Analysis

The use of analytical sciences in the discovery, development andmanufacture of pharmaceuticals is wide-ranging. From the analysisof minute amounts of complex biological materials to the qualitycontrol of the final dosage form, the use of analytical technologycovers an immense range of techniques and disciplines. This book concentrates on the analytical aspects of drugdevelopment and manufacture, focusing on the analysis of the activeingredient or drug substance. It provides those joining theindustry or other areas of pharmaceutical research with a source ofreference to

Coupling of Capillary Electrophoresis with Nuclear Magnetic Resonance Spectroscopy for the Analysis of Pharmaceutical and Environmental Relevant Compo

Coupling of Capillary Electrophoresis with Nuclear Magnetic Resonance Spectroscopy for the Analysis of Pharmaceutical and Environmental Relevant Compo
  • Author : Joana Diekmann
  • Publisher : GRIN Verlag
  • Release : 01 April 2011
GET THIS BOOK Coupling of Capillary Electrophoresis with Nuclear Magnetic Resonance Spectroscopy for the Analysis of Pharmaceutical and Environmental Relevant Compo

Master's Thesis from the year 2009 in the subject Chemistry - Analytical Chemistry, grade: 1,0, University of Hannover (Anorganische Chemie), language: English, comment: This Master Thesis was awarded with the "E.ON Future Award 2010" and it was carried out at the Leibniz University Hannover, Faculty of Natural Sciences, Institute for Inorganic Chemistry, Department of Analytical Chemistry, in cooperation with the Lawrence Livermore National Laboratory, Physical and Life Sciences Directorate, Livermore, CA, USA., abstract: Separation and identification of mass-limited chemical samples is the

Spectroscopic Analyses

Spectroscopic Analyses
  • Author : Eram Sharmin,Fahmina Zafar
  • Publisher : BoD – Books on Demand
  • Release : 06 December 2017
GET THIS BOOK Spectroscopic Analyses

The book presents developments and applications of these methods, such as NMR, mass, and others, including their applications in pharmaceutical and biomedical analyses. The book is divided into two sections. The first section covers spectroscopic methods, their applications, and their significance as characterization tools; the second section is dedicated to the applications of spectrophotometric methods in pharmaceutical and biomedical analyses. This book would be useful for students, scholars, and scientists engaged in synthesis, analyses, and applications of materials/polymers.

Process Analytical Technology

Process Analytical Technology
  • Author : Katherine A. Bakeev
  • Publisher : John Wiley & Sons
  • Release : 01 April 2010
GET THIS BOOK Process Analytical Technology

Process Analytical Technology explores the concepts of PAT and its application in the chemical and pharmaceutical industry from the point of view of the analytical chemist. In this new edition all of the original chapters have been updated and revised, and new chapters covering the important topics of sampling, NMR, fluorescence, and acoustic chemometrics have been added. Coverage includes: Implementation of Process Analytical Technologies UV-Visible Spectroscopy for On-line Analysis Infrared Spectroscopy for Process Analytical Applications Process Raman Spectroscopy Process NMR

NMR in Pharmaceutical Science

NMR in Pharmaceutical Science
  • Author : Jeremy R. Everett,Robin K. Harris,John C. Lindon,Ian D. Wilson
  • Publisher : John Wiley & Sons
  • Release : 24 August 2015
GET THIS BOOK NMR in Pharmaceutical Science

NMR in Pharmaceutical Sciences is intended to be a comprehensive source of information for the many individuals that utilize MR in studies of relevance to the pharmaceutical sector. The book is intended to educate and inform those who develop and apply MR approaches within the wider pharmaceutical environment, emphasizing the toolbox that is available to spectroscopists and radiologists. This book is structured on the key processes in drug discovery, development and manufacture, but underpinned by an understanding of fundamental NMR

Quantitative NMR Spectroscopy in Pharmaceuticals

Quantitative NMR Spectroscopy in Pharmaceuticals
  • Author : Kalpesh S. Parikh,Hemant H. Gadape
  • Publisher : LAP Lambert Academic Publishing
  • Release : 01 March 2012
GET THIS BOOK Quantitative NMR Spectroscopy in Pharmaceuticals

Over the past fifty years nuclear magnetic resonance spectroscopy, commonly referred to as NMR, has become the preeminent technique for structure determination of organic compounds. With developments in both methodology and instrumentation in the past two decades, NMR has become one of the most powerful and versatile spectroscopic techniques for characterization and quantification. An increasing concern with the well being of individuals and life in general has led to initiatives for improvements in medicine and the world environment, and in

Natural Products Analysis

Natural Products Analysis
  • Author : Vladimir Havlicek,Jaroslav Spizek
  • Publisher : John Wiley & Sons
  • Release : 17 September 2014
GET THIS BOOK Natural Products Analysis

This book highlights analytical chemistry instrumentation andpractices applied to the analysis of natural products and theircomplex mixtures, describing techniques for isolating andcharacterizing natural products. • Applies analytical techniques to natural productsresearch – an area of critical importance to drugdiscovery • Offers a one-stop shop for most analytical methods:x-ray diffraction, NMR analysis, mass spectrometry, and chemicalgenetics • Includes coverage of natural products basics andhighlights antibacterial research, particularly important asefforts to combat drug resistance gain prominence • Covers instrumental techniques with enough detail forboth current practitioners

Analysis of Drug Impurities

Analysis of Drug Impurities
  • Author : Richard J. Smith,Michael L. Webb
  • Publisher : John Wiley & Sons
  • Release : 15 April 2008
GET THIS BOOK Analysis of Drug Impurities

A key component of the overall quality of a pharmaceutical is control of impurities, as their presence, even in small amounts, may affect drug safety and efficacy. The identification and quantification of impurities to acceptable standards presents a significant challenge to the analytical chemist. Analytical science is developing rapidly and provides increasing opportunity to identify the structure, and therefore the origin and safety implications of these impurities, and the challenges of their measurement drives the development of modern quantitative methods.

Implementation of Solution and Solid Sate Nuclear Magnetic Resonance NMR Spectroscopic Techniques for Quantitative and Qualitative Analysis of Molecular Species

Implementation of Solution and Solid Sate Nuclear Magnetic Resonance  NMR  Spectroscopic Techniques for Quantitative and Qualitative Analysis of Molecular Species
  • Author : Abrar S. Alnafisah
  • Publisher : Unknown
  • Release : 15 June 2021
GET THIS BOOK Implementation of Solution and Solid Sate Nuclear Magnetic Resonance NMR Spectroscopic Techniques for Quantitative and Qualitative Analysis of Molecular Species

In this dissertation, spectroscopy has been used to solve a variety of problems in different domains of science. Therefore, each chapter consists of different examples that have been addressed using different concepts of spectroscopy. The objective of part I (application of solution state NMR spectroscopy in pharmaceutical sciences) is to apply NMR techniques in different pharmaceutical projects. In chapter 3, a real-time quantification of in vitro Bortezomib (BTZ) release from alginate microparticles using a solution state quantitative boron nuclear magnetic resonance (11

LC NMR and Other Hyphenated NMR Techniques

LC NMR and Other Hyphenated NMR Techniques
  • Author : Maria V. Silva Elipe
  • Publisher : John Wiley & Sons
  • Release : 20 December 2011
GET THIS BOOK LC NMR and Other Hyphenated NMR Techniques

This practical guide provides a basic overview of the pros and cons of NMR spectroscopy as both a hyphenated and non-hyphenated technique. The book begins with a description of basic NMR concepts for the structural elucidation of organic compounds and then details the historical development of NMR and hyphenated NMR in the structural elucidation world, followed by applications of hyphenated NMR as LC-NMR and LC-MS-NMR in industry and academia. It also contains updated information on the latest advancements and applications