Nmr Spectroscopy In Pharmaceutical Analysis

Nmr Spectroscopy In Pharmaceutical Analysis Book PDF
✏Book Title : NMR Spectroscopy in Pharmaceutical Analysis
✏Author : Iwona Wawer
✏Publisher : Elsevier
✏Release Date : 2017-07-07
✏Pages : 528
✏ISBN : 9780080951522
✏Available Language : English, Spanish, And French

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✏NMR Spectroscopy in Pharmaceutical Analysis Book Summary : For almost a decade, quantitative NMR spectroscopy (qNMR) has been established as valuable tool in drug analysis. In all disciplines, i. e. drug identification, impurity profiling and assay, qNMR can be utilized. Separation techniques such as high performance liquid chromatography, gas chromatography, super fluid chromatography and capillary electrophoresis techniques, govern the purity evaluation of drugs. However, these techniques are not always able to solve the analytical problems often resulting in insufficient methods. Nevertheless such methods find their way into international pharmacopoeias. Thus, the aim of the book is to describe the possibilities of qNMR in pharmaceutical analysis. Beside the introduction to the physical fundamentals and techniques the principles of the application in drug analysis are described: quality evaluation of drugs, polymer characterization, natural products and corresponding reference compounds, metabolism, and solid phase NMR spectroscopy for the characterization drug substances, e.g. the water content, polymorphism, and drug formulations, e.g. tablets, powders. This part is accompanied by more special chapters dealing with representative examples. They give more detailed information by means of concrete examples. Combines theory, techniques, and concrete applications—all of which closely resemble the laboratory experience Considers international pharmacopoeias, addressing the concern for licensing Features the work of academics and researchers, appealing to a broad readership

Nmr Spectroscopy In Drug Development And Analysis Book PDF
✏Book Title : NMR Spectroscopy in Drug Development and Analysis
✏Author : Ulrike Holzgrabe
✏Publisher : John Wiley & Sons
✏Release Date : 2008-07-11
✏Pages : 312
✏ISBN : 9783527613656
✏Available Language : English, Spanish, And French

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✏NMR Spectroscopy in Drug Development and Analysis Book Summary : Since the development of the NMR spectrometer in the 1950s, NMR spectra have been widely used for the elucidation of the 2D structure of newly synthesized and natural compounds. In the 1980s, the high-resolution NMR spectrometer (> 300 Mhz) and 2D experiments were introduced, which opens up the possibility to determine the 3D structure of large molecules, especially biomolecules. However, NMR spectroscopy has been rarely applied to drug analysis. This book illustrates the power and versatility of NMR spectroscopy in the determination of impurities in and the content of drugs, the composition of polymer excipients, the characterization of isomeric drug mixtures, the complexity of drugs with small-size components or ions, and the behavior of drugs in acid and basic solution. In addition, NMR spectroscopy and especially the hyphenated technique with HPLC is shown to be a powerful tool to measure a drug and its metabolites in various body fluids. The solid state NMR technique can give information on the structure, especially the conformation of drugs and excipients in drug formulations. Recently, SAR by NMR, introduced by Fesik, impressively demonstrated the potential of NMR spectroscopy in drug development and in the characterization of the interaction between large molecules and ligands. The complexation between proteins, lipids and cyclodextrins with drugs is described. Finally, NMR imaging (MRI and MRS) can be used to characterize the liberation of drugs from a drug formulation. Furthermore, the distribution of substances in plants, in animals, in tissues and in humans can be visualized by imaging. In short, this book covers all aspects of drug analysis.

Annual Reports On Nmr Spectroscopy Book PDF
✏Book Title : Annual Reports on NMR Spectroscopy
✏Author : Graham A. Webb
✏Publisher : Academic Press
✏Release Date : 2013-09-27
✏Pages : 448
✏ISBN : 9780124079045
✏Available Language : English, Spanish, And French

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✏Annual Reports on NMR Spectroscopy Book Summary : Nuclear magnetic resonance (NMR) is an analytical tool used by chemists and physicists to study the structure and dynamics of molecules. In recent years, no other technique has gained such significance as NMR spectroscopy. It is used in all branches of science in which precise structural determination is required and in which the nature of interactions and reactions in solution is being studied. Annual Reports on NMR Spectroscopy has established itself as a premier means for the specialist and non-specialist alike to become familiar with new techniques and applications of NMR spectroscopy. This volume of Annual Reports on NMR Spectroscopy focuses on the analytical tool used by chemists and physicists and inlcudes topics such as Profiling of Food Samples, Recent Advances in Solution NMR Studies and Magic Angle Spinning NMR Studies of Protein Assemblies

📒Pharmaceutical Analysis ✍ David C Lee

Pharmaceutical Analysis Book PDF
✏Book Title : Pharmaceutical Analysis
✏Author : David C Lee
✏Publisher : John Wiley & Sons
✏Release Date : 2009-02-12
✏Pages : 384
✏ISBN : 9781405172998
✏Available Language : English, Spanish, And French

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✏Pharmaceutical Analysis Book Summary : The use of analytical sciences in the discovery, development andmanufacture of pharmaceuticals is wide-ranging. From the analysisof minute amounts of complex biological materials to the qualitycontrol of the final dosage form, the use of analytical technologycovers an immense range of techniques and disciplines. This book concentrates on the analytical aspects of drugdevelopment and manufacture, focusing on the analysis of the activeingredient or drug substance. It provides those joining theindustry or other areas of pharmaceutical research with a source ofreference to a broad range of techniques and their applications,allowing them to choose the most appropriate analytical techniquefor a particular purpose. The volume is directed at analytical chemists, industrialpharmacists, organic chemists, pharmaceutical chemists andbiochemists.

Pharmaceutical Analysis A Textbook For Pharmacy Students And Pharmaceutical Chemists 3 Book PDF
✏Book Title : Pharmaceutical Analysis A Textbook for Pharmacy Students and Pharmaceutical Chemists 3
✏Author : David G. Watson
✏Publisher : Elsevier Health Sciences
✏Release Date : 2012
✏Pages : 427
✏ISBN : 9780702046216
✏Available Language : English, Spanish, And French

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✏Pharmaceutical Analysis A Textbook for Pharmacy Students and Pharmaceutical Chemists 3 Book Summary : An introductory text, written with the needs of the student in mind, which explains all the most important techniques used in the analysis of pharmaceuticals - a key procedure in ensuring the quality of drugs. The text is enhanced throughout with keypoints and self-assessment boxes, to aid student learning.

Pharmaceutical Drug Analysis Book PDF
✏Book Title : Pharmaceutical Drug Analysis
✏Author : Ashutosh Kar
✏Publisher : New Age International
✏Release Date : 2005-12
✏Pages : 554
✏ISBN : 8122415822
✏Available Language : English, Spanish, And French

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✏Pharmaceutical Drug Analysis Book Summary : About the Book: During the past two decades, there have been magnificent and significant advances in both analytical instrumentation and computerized data handling devices across the globe. In this specific context the remarkable proliferation of windows

📒Nmr In Pharmaceutical Science ✍ Robin K. Harris

Nmr In Pharmaceutical Science Book PDF
✏Book Title : NMR in Pharmaceutical Science
✏Author : Robin K. Harris
✏Publisher : John Wiley & Sons
✏Release Date : 2015-09-28
✏Pages : 504
✏ISBN : 9781118660256
✏Available Language : English, Spanish, And French

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✏NMR in Pharmaceutical Science Book Summary : NMR in Pharmaceutical Sciences is intended to be a comprehensive source of information for the many individuals that utilize MR in studies of relevance to the pharmaceutical sector. The book is intended to educate and inform those who develop and apply MR approaches within the wider pharmaceutical environment, emphasizing the toolbox that is available to spectroscopists and radiologists. This book is structured on the key processes in drug discovery, development and manufacture, but underpinned by an understanding of fundamental NMR principles and the unique contribution that NMR (including MRI) can provide. After an introductory chapter, which constitutes an overview, the content is organised into five sections. The first section is on the basics of NMR theory and relevant experimental methods. The rest follow a sequence based on the chronology of drug discovery and development, firstly 'Idea to Lead' then 'Lead to Drug Candidate', followed by 'Clinical Development', and finally 'Drug Manufacture'. The thirty one chapters cover a vast range of topics from analytical chemistry, including aspects involved in regulatory matters and in the prevention of fraud, to clinical imaging studies. Whilst this comprehensive volume will be essential reading for many scientists based in pharmaceutical and related industries, it should also be of considerable value to a much wider range of academic scientists whose research is related to the various aspects of pharmaceutical R&D; for them it will supply vital understanding of pharmaceutical industrial concerns and the basis of key decision making processes. About eMagRes Handbooks eMagRes (formerly the Encyclopedia of Magnetic Resonance) publishes a wide range of online articles on all aspects of magnetic resonance in physics, chemistry, biology and medicine. The existence of this large number of articles, written by experts in various fields, is enabling the publication of a series of eMagRes Handbooks on specific areas of NMR and MRI. The chapters of each of these handbooks will comprise a carefully chosen selection of eMagRes articles. In consultation with the eMagRes Editorial Board, the eMagRes handbooks are coherently planned in advance by specially-selected Editors, and new articles are written to give appropriate complete coverage. The handbooks are intended to be of value and interest to research students, postdoctoral fellows and other researchers learning about the scientific area in question and undertaking relevant experiments, whether in academia or industry. Have the content of this handbook and the complete content of eMagRes at your fingertips! Visit: www.wileyonlinelibrary.com/ref/eMagRes

Peptide And Protein Drug Analysis Book PDF
✏Book Title : Peptide and Protein Drug Analysis
✏Author : Ronald Reid
✏Publisher : CRC Press
✏Release Date : 1999-11-12
✏Pages : 904
✏ISBN : 1420001337
✏Available Language : English, Spanish, And French

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✏Peptide and Protein Drug Analysis Book Summary : Furthering efforts to simulate the potency and specificity exhibited by peptides and proteins in healthy cells, this remarkable reference supplies pharmaceutical scientists with a wealth of techniques for tapping the enormous therapeutic potential of these molecules-providing a solid basis of knowledge for new drug design. Provides a broad, comprehensive overview of peptides and proteins as mediators of cell movement, proliferation, differentiation, and communication. Written by more than 50 leading international authorities, Peptides and Protein Drug Analysis discusses strategies for dealing with the complexity of peptides and proteins in conformational flexibility and amino acid sequence variability analyzes drug formulations facilitated by solid-phase peptide synthesis and recombinant DNA technology examines chemical purity analysis by high-pressure chromatographic, capillary electrophoretic, gel electrophoretic, and isoelectric focusing methods highlights drug design elements derived from protein folding, bioinformatics, and computational chemistry demonstrates uses of unnatural mutagenesis and combinatorial chemistry explores mass spectrometry, protein sequence, and carbohydrate analysis illustrates bioassays and other new functional analysis methods surveys spectroscopic techniques such as ultraviolet, fluorescence, Fourier transform infrared, and nuclear magnetic resonance (NMR) addresses ways of distinguishing between levels of therapeutic and endogenous agents in cells reviews structural analysis tools such as ultracentrifugation and light, X-ray, and neutron scattering and more! Featuring over 3400 bibliographic citations and more than 500 tables, equations, and illustrations, Peptide and Protein Drug Analysis is a must-read resource for pharmacists; pharmacologists; analytical, organic, and pharmaceutical chemists; cell and molecular biologists; biochemists; and upper-level undergraduate and graduate students in these disciplines.

📒Pharmaceutical Excipients ✍ David E. Bugay

Pharmaceutical Excipients Book PDF
✏Book Title : Pharmaceutical Excipients
✏Author : David E. Bugay
✏Publisher : CRC Press
✏Release Date : 1999-02-23
✏Pages : 688
✏ISBN : 0824793730
✏Available Language : English, Spanish, And French

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✏Pharmaceutical Excipients Book Summary : Meeting the need for a hands-on guide elucidating the role of molecular spectroscopy in the physical characterization of pharmaceutical solids, two experts from the industry gather theoretical discussions of infrared, Raman, and nuclear magnetic resonance spectroscopy. They provide recommendations on spectral data acquisition techniques and include 600 spectra for 300 of the most commonly used excipients. Complete with references, equations, tables, and a CAS registry number index, the book covers the drug development process, including chemical identification of substances, investigative studies, competitor analysis, problem solving activities, reproduction of spectral data, and more.

📒Polymorphism ✍ Rolf Hilfiker

Polymorphism Book PDF
✏Book Title : Polymorphism
✏Author : Rolf Hilfiker
✏Publisher : John Wiley & Sons
✏Release Date : 2006-08-21
✏Pages : 433
✏ISBN : 9783527607723
✏Available Language : English, Spanish, And French

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✏Polymorphism Book Summary : Edited by one of the leading experts in the field, this handbook emphasizes why solid-state issues are important, which approaches should be taken to avoid problems and exploit the opportunities offered by solid state properties in the pharmaceutical and agricultural industries. With its practical approach, this is at once a guideline for development chemists just entering the field as well as a high-quality source of reference material for specialists in the pharmaceutical and chemical industry, structural chemists, physicochemists, crystallographers, inorganic chemists, and patent departments.

Methods For Structural Analysis Of Protein Pharmaceuticals Book PDF
✏Book Title : Methods for Structural Analysis of Protein Pharmaceuticals
✏Author : Wim Jiskoot
✏Publisher : Springer Science & Business Media
✏Release Date : 2005-12-05
✏Pages : 678
✏ISBN : 0971176728
✏Available Language : English, Spanish, And French

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✏Methods for Structural Analysis of Protein Pharmaceuticals Book Summary : Protein pharmaceuticals form a fast-growing category in the arsenal of drugs. This book explores the nature of different analytical techniques and the way in which they are related to pharmaceutical proteins. In addition to serving the analytical chemist, this book is needed by the formulation scientist who is responsible for design and formulation of a pharmaceutical protein that can be monitored during production and over time.

📒Spectroscopic Analyses ✍ Eram Sharmin

Spectroscopic Analyses Book PDF
✏Book Title : Spectroscopic Analyses
✏Author : Eram Sharmin
✏Publisher : BoD – Books on Demand
✏Release Date : 2017-12-06
✏Pages : 240
✏ISBN : 9789535136279
✏Available Language : English, Spanish, And French

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✏Spectroscopic Analyses Book Summary : The book presents developments and applications of these methods, such as NMR, mass, and others, including their applications in pharmaceutical and biomedical analyses. The book is divided into two sections. The first section covers spectroscopic methods, their applications, and their significance as characterization tools; the second section is dedicated to the applications of spectrophotometric methods in pharmaceutical and biomedical analyses. This book would be useful for students, scholars, and scientists engaged in synthesis, analyses, and applications of materials/polymers.

Structure Activity Relationship Studies In Drug Development By Nmr Spectroscopy Book PDF
✏Book Title : Structure activity Relationship Studies in Drug Development by NMR Spectroscopy
✏Author : Atta-ur- Rahman
✏Publisher : Bentham Science Publishers
✏Release Date : 2011
✏Pages : 214
✏ISBN : 9781608051649
✏Available Language : English, Spanish, And French

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✏Structure activity Relationship Studies in Drug Development by NMR Spectroscopy Book Summary : "NMR (Nuclear Magnetic Resonance) Spectroscopy has found significant applications in drug discovery based on its capacity to map molecular interactions at the atomic level. Chemical shifts, cross relaxation, and exchange of protons are among the NMR parame"

📒Handbook Of Spectroscopy ✍ G¿nter Gauglitz

Handbook Of Spectroscopy Book PDF
✏Book Title : Handbook of Spectroscopy
✏Author : G¿nter Gauglitz
✏Publisher : John Wiley & Sons
✏Release Date : 2014-05-05
✏Pages : 1993
✏ISBN : 9783527654727
✏Available Language : English, Spanish, And French

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✏Handbook of Spectroscopy Book Summary : This second, thoroughly revised, updated and enlarged edition provides a straightforward introduction to spectroscopy, showing what it can do and how it does it, together with a clear, integrated and objective account of the wealth of information that may be derived from spectra. It also features new chapters on spectroscopy in nano-dimensions, nano-optics, and polymer analysis. Clearly structured into sixteen sections, it covers everything from spectroscopy in nanodimensions to medicinal applications, spanning a wide range of the electromagnetic spectrum and the physical processes involved, from nuclear phenomena to molecular rotation processes. In addition, data tables provide a comparison of different methods in a standardized form, allowing readers to save valuable time in the decision process by avoiding wrong turns, and also help in selecting the instrumentation and performing the experiments. These four volumes are a must-have companion for daily use in every lab.

Structure Elucidation In Organic Chemistry Book PDF
✏Book Title : Structure Elucidation in Organic Chemistry
✏Author : Maria-Magdalena Cid
✏Publisher : John Wiley & Sons
✏Release Date : 2015-01-05
✏Pages : 552
✏ISBN : 9783527664634
✏Available Language : English, Spanish, And French

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✏Structure Elucidation in Organic Chemistry Book Summary : Intended for advanced readers, this is a review of all relevant techniques for structure analysis in one handy volume. As such, it provides the latest knowledge on spectroscopic and related techniques for chemical structure analysis, such as NMR, optical spectroscopy, mass spectrometry and X-ray crystallography, including the scope and limitation of each method. As a result, readers not only become acquainted with the techniques, but also the advantages of the synergy between them. This enables them to choose the correct analytical method for each problem, saving both time and resources. Special emphasis is placed on NMR and its application to absolute configuration determination and the analysis of molecular interactions. Adopting a practical point of view, the author team from academia and industry guarantees both solid methodology and applications essential for structure determination, equipping experts as well as newcomers with the tools to solve any structural problem.

📒Process Analytical Technology ✍ Katherine A. Bakeev

Process Analytical Technology Book PDF
✏Book Title : Process Analytical Technology
✏Author : Katherine A. Bakeev
✏Publisher : John Wiley & Sons
✏Release Date : 2010-04-01
✏Pages : 576
✏ISBN : 9780470689608
✏Available Language : English, Spanish, And French

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✏Process Analytical Technology Book Summary : Process Analytical Technology explores the concepts of PAT and its application in the chemical and pharmaceutical industry from the point of view of the analytical chemist. In this new edition all of the original chapters have been updated and revised, and new chapters covering the important topics of sampling, NMR, fluorescence, and acoustic chemometrics have been added. Coverage includes: Implementation of Process Analytical Technologies UV-Visible Spectroscopy for On-line Analysis Infrared Spectroscopy for Process Analytical Applications Process Raman Spectroscopy Process NMR Spectrscopy: Technology and On-line Applications Fluorescent Sensing and Process Analytical Applications Chemometrics in Process Analytical Technology (PAT) On-Line PAT Applications of Spectroscopy in the Pharmaceutical Industry Future Trends for PAT for Increased Process Understanding and Growing Applications in Biomanufacturing NIR Chemical Imaging This volume is an important starting point for anyone wanting to implement PAT and is intended not only to assist a newcomer to the field but also to provide up-to-date information for those who practice process analytical chemistry and PAT. It is relevant for chemists, chemical and process engineers, and analytical chemists working on process development, scale-up and production in the pharmaceutical, fine and specialty chemicals industries, as well as for academic chemistry, chemical engineering, chemometrics and pharmaceutical science research groups focussing on PAT. Review from the First Edition “The book provides an excellent first port of call for anyone seeking material and discussions to understand the area better. It deserves to be found in every library that serves those who are active in the field of Process Analytical Technology.”—Current Engineering Practice

Instrumental Methods Of Drug Analysis Book PDF
✏Book Title : Instrumental Methods of Drug Analysis
✏Author : G. Vidya Sagar
✏Publisher : Pharmamed Press
✏Release Date : 2009
✏Pages : 551
✏ISBN : 1441668608
✏Available Language : English, Spanish, And French

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✏Instrumental Methods of Drug Analysis Book Summary : 1 . Chromatography 2. Column Chromatography 3. Thin Layer Chromatography 4. Paper Chromatography 5. Ion Exchange Chromatography 6. Gas Chromatography 7. High Performance Liquid Chromatography 8. High Performance Thin Layer Chromatography 9. Introduction to Spectroscopy 10. UV & Visible Spectroscopy 11. Flourimetry 12. Nephelometry and Turbidimetry 13. Atomic Absorption Spectroscopy 14. Flame Photometry 15. Mass Spectroscopy 16. Infrared Spectroscopy 17 . Nuclear Magnetic Resonance Spectroscopy 18. Water Analysis 19. Validation 20. X-ray Spectroscopy Question Bank

Pharmaceutical Analysis E Book Book PDF
✏Book Title : Pharmaceutical Analysis E Book
✏Author : David G. Watson
✏Publisher : Elsevier Health Sciences
✏Release Date : 2020-06-10
✏Pages : 480
✏ISBN : 9780702078095
✏Available Language : English, Spanish, And French

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✏Pharmaceutical Analysis E Book Book Summary : Pharmaceutical analysis determines the purity, concentration, active compounds, shelf life, rate of absorption in the body, identity, stability, rate of release etc. of a drug. Testing a pharmaceutical product involves a variety of analyses, and the analytical processes described in this book are used in industries as diverse as food, beverages, cosmetics, detergents, metals, paints, water, agrochemicals, biotechnological products and pharmaceuticals. The mathematics involved is notoriously difficult, but this much-praised and well established textbook, now revised and updated for its fifth edition, guides a student through the complexities with clear writing and the author's expertise from many years' teaching pharmacy students. Worked calculation examples and self-assessment test questions aid continuous learning reinforcement throughout Frequent use of figures and diagrams clarify points made in the text Practical examples are used to show the application of techniques Key points boxes summarise the need to know information for each topic Focuses on the most relevant and frequently used techniques within the field

Polymorphism In Pharmaceutical Solids Second Edition Book PDF
✏Book Title : Polymorphism in Pharmaceutical Solids Second Edition
✏Author : Harry G. Brittain
✏Publisher : CRC Press
✏Release Date : 2016-04-19
✏Pages : 656
✏ISBN : 9781420073225
✏Available Language : English, Spanish, And French

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✏Polymorphism in Pharmaceutical Solids Second Edition Book Summary : Using clear and practical examples, Polymorphism of Pharmaceutical Solids, Second Edition presents a comprehensive examination of polymorphic behavior in pharmaceutical development that is ideal for pharmaceutical development scientists and graduate students in pharmaceutical science. This edition focuses on pharmaceutical aspects of polymorphism and solvatomorphism, while systematically explaining their thermodynamic and structural origins. Topics include: Computational methodologies High-throughput screening methods Pharmaceutical cocrystals Thermally-induced and solution-mediated phase transformations Amorphous solids Crystallography preparation and characterization The amorphous state

Biwic 2007 14th International Workshop On Industrial Crystallization Book PDF
✏Book Title : BIWIC 2007 14th International Workshop on Industrial Crystallization
✏Author : A.E. Lewis
✏Publisher : IOS Press
✏Release Date : 2007-08-31
✏Pages : 284
✏ISBN : 9781607502784
✏Available Language : English, Spanish, And French

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✏BIWIC 2007 14th International Workshop on Industrial Crystallization Book Summary : The field of crystallization holds many challenges, with the physical and chemical complexity of the crystallization process being core to the dynamic nature of the field. Exciting advances are currently being achieved in the areas of nanoparticle formation, product and particle design and methods of particle characterisation. There is also significant progress and innovation in the design, scale-up and control of crystallizers. These key developments are reflected in the session themes of the 14th BIWIC (Bremen International Workshop on Industrial Crystallization) with the technical programme incorporating a wide range of topics, such as; The formation and stabilisation of nano particles; Polymorphs and co-crystals in pharmaceutical preparation; Product and particle design; Kinetics of crystallization and measurement of crystal properties; Freeze, Antisolvent, Reactive and Melt crystallization; and Design, scale-up and control of crystallization processes at the industrial scale.

New Applications Of Nmr In Drug Discovery And Development Book PDF
✏Book Title : New Applications of NMR in Drug Discovery and Development
✏Author : Leoncio Garrido
✏Publisher : Royal Society of Chemistry
✏Release Date : 2013-07-24
✏Pages : 565
✏ISBN : 9781849734448
✏Available Language : English, Spanish, And French

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✏New Applications of NMR in Drug Discovery and Development Book Summary : This book presents a review of new developments in NMR for applications in medicinal chemistry and drug discovery. The contents will focus on consolidated and emerging techniques and methods that are at present not widely applied, however it is considered that they could contribute to the advancement of drug discovery and drug development.

📒Essentials Of Pharmaceutical Analysis ✍ Muhammad Sajid Hamid Akash

Essentials Of Pharmaceutical Analysis Book PDF
✏Book Title : Essentials of Pharmaceutical Analysis
✏Author : Muhammad Sajid Hamid Akash
✏Publisher : Springer Nature
✏Release Date : 2019-12-17
✏Pages : 222
✏ISBN : 9789811515477
✏Available Language : English, Spanish, And French

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✏Essentials of Pharmaceutical Analysis Book Summary : Recent advances in the pharmaceutical sciences and biotechnology have facilitated the production, design, formulation and use of various types of pharmaceuticals and biopharmaceuticals. This book provides detailed information on the background, basic principles, and components of techniques used for the analysis of pharmaceuticals and biopharmaceuticals. Focusing on those analytical techniques that are most frequently used for pharmaceuticals, it classifies them into three major sections and 19 chapters, each of which discusses a respective technique in detail. Chiefly intended for graduate students in the pharmaceutical sciences, the book will familiarize them with the components, working principles and practical applications of these indispensable analytical techniques.

High Throughput Analysis In The Pharmaceutical Industry Book PDF
✏Book Title : High Throughput Analysis in the Pharmaceutical Industry
✏Author : Perry G. Wang
✏Publisher : CRC Press
✏Release Date : 2008-08-20
✏Pages : 432
✏ISBN : 1420059548
✏Available Language : English, Spanish, And French

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✏High Throughput Analysis in the Pharmaceutical Industry Book Summary : The introduction of combinatorial chemistry technology has increased the amount of compounds generated in a year from 50 to 2000. Conventional analytical approaches simply cannot keep up. These circumstances have caused drug discovery to take on the shape of a bottleneck, like traffic through a toll booth. In order to break the bottleneck, a corresponding revolutionary improvement to the conventional methodology must happen.

New Advances In Analytical Chemistry Book PDF
✏Book Title : New Advances in Analytical Chemistry
✏Author : Atta-ur Rahman
✏Publisher : CRC Press
✏Release Date : 2002-04-11
✏Pages : 360
✏ISBN : 0415272246
✏Available Language : English, Spanish, And French

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✏New Advances in Analytical Chemistry Book Summary : New Advances in Analytical Chemistry, Volume 3 presents recent developments in various spectroscopic techniques such as NMR spectroscopy and mass spectroscopy in the form of comprehensive reviews written by leading authorities in the field. With new and updated information. the book is invaluable to both research students and postdoctoral workers who wish to keep abreast of frontiers in analytical techniques. Each chapter provides a broad overall account of recent developments, so that the readers can stay current not only with the authors own contributions but also with contributions of other eminent scientists working in this area.

Approaches To The Conformational Analysis Of Biopharmaceuticals Book PDF
✏Book Title : Approaches to the Conformational Analysis of Biopharmaceuticals
✏Author : Roger L. Lundblad
✏Publisher : CRC Press
✏Release Date : 2009-12-15
✏Pages : 366
✏ISBN : 1439807817
✏Available Language : English, Spanish, And French

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✏Approaches to the Conformational Analysis of Biopharmaceuticals Book Summary : The activity of many biopharmaceutical polymers is dependent on conformation, and the next several years will see increased interest in the conformational analysis of these polymers resulting from the development of biosimilar or "follow-on" biological products. While a wide variety of approaches to analysis exists, finding the most viable ones would be much easier with a consolidated reference that details the benefits and cost of each approach, with an emphasis on real results and real products. Explores the Growing Role of Conformational Analysis in Comparing Generic Biopharmaceuticals Approaches to the Conformational Analysis of Biopharmaceuticals gathers the most useful techniques and methods into a single volume, putting the greatest emphasis on those approaches that have proven the most fruitful. Rather than cover specific uses of techniques in detail, this book provides commercial biotechnologists and researchers with the information and references they need to make good choices about the technology they choose to use. With a large number of references that direct readers to primary source material, it includes studies drawn from the gamut of current literature, covering physical methods, such as differential scanning calorimetry, light scanning, and analytical ultracentrifugation. It also addresses chemical methods, such as hydrogen–deuterium exchange and trace labeling, along with infrared, ultraviolet, and Raman spectroscopy. Written by Roger Lundblad, a true pioneer in protein science, this volume supplies the necessary information researchers need to access when deciding on the most cost-effective approach, including: Comparability of biopharmaceuticals Characterization of follow-on biologics Quality attributes of protein biopharmaceuticals Confrontational analysis of biopharmaceutical products With a clear focus on relevant commercial biotechnology, this book belongs on the shelves of those serious researchers who are paving the way for the next generation of biopharmaceutical polymers.

📒Modern Magnetic Resonance ✍ Graham A. Webb

Modern Magnetic Resonance Book PDF
✏Book Title : Modern Magnetic Resonance
✏Author : Graham A. Webb
✏Publisher : Springer Science & Business Media
✏Release Date : 2007-05-26
✏Pages : 1926
✏ISBN : 9781402039102
✏Available Language : English, Spanish, And French

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✏Modern Magnetic Resonance Book Summary : A comprehensive collection of the applications of Nuclear Magnetic Resonance (NMR), Magnetic Resonance Imaging (MRI) and Electron-Spin Resonance (ESR). Covers the wide ranging disciplines in which these techniques are used: * Chemistry; * Biological Sciences; * Pharmaceutical Sciences; * Medical uses; * Marine Science; * Materials Science; * Food Science. Illustrates many techniques through the applications described, e.g.: * High resolution solid and liquid state NMR; * Low resolution NMR, especially important in food science; * Solution State NMR, especially important in pharmaceutical sciences; * Magnetic Resonance Imaging, especially important for medical uses; * Electron Spin Resonance, especially important for spin-labelling in food, marine and medical studies.

Modern Methods Of Pharmaceutical Analysis Book PDF
✏Book Title : Modern Methods of Pharmaceutical Analysis
✏Author : Roger E. Schirmer
✏Publisher :
✏Release Date : 1982
✏Pages : 252
✏ISBN : 0849352452
✏Available Language : English, Spanish, And French

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✏Modern Methods of Pharmaceutical Analysis Book Summary :

📒Nuclear Magnetic Resonance ✍ Royal Society of Chemistry (Great Britain)

Nuclear Magnetic Resonance Book PDF
✏Book Title : Nuclear Magnetic Resonance
✏Author : Royal Society of Chemistry (Great Britain)
✏Publisher : Royal Society of Chemistry
✏Release Date : 2003
✏Pages : 586
✏ISBN : 085404342X
✏Available Language : English, Spanish, And French

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✏Nuclear Magnetic Resonance Book Summary : For those wanting to become rapidly acquainted with specific areas of NMR, this title provides unrivalled scope of coverage.

A Textbook Of Pharmaceutical Analysis Book PDF
✏Book Title : A Textbook of Pharmaceutical Analysis
✏Author : Kenneth A. Connors
✏Publisher : Wiley-Interscience
✏Release Date : 1975
✏Pages : 611
✏ISBN : UOM:39015000844418
✏Available Language : English, Spanish, And French

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✏A Textbook of Pharmaceutical Analysis Book Summary :

📒Lc Nmr ✍ Nina C. Gonnella

Lc Nmr Book PDF
✏Book Title : LC NMR
✏Author : Nina C. Gonnella
✏Publisher : CRC Press
✏Release Date : 2013-03-15
✏Pages : 301
✏ISBN : 9781439875070
✏Available Language : English, Spanish, And French

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✏LC NMR Book Summary : The isolation and structural characterization of substances present at very low concentrations, as is necessary to satisfy regulatory requirements for pharmaceutical drug degradants and impurities, can present scientific challenges. The coupling of HPLC with NMR spectroscopy has been at the forefront of cutting-edge technologies to address these issues. LC-NMR: Expanding the Limits of Structure Elucidation presents a comprehensive overview of key concepts in HPLC and NMR that are required to achieve definitive structure elucidation with very low levels of analytes. Because skill sets from both of these highly established disciplines are involved in LC-NMR, the author provides introductory background to facilitate readers’ proficiency in both areas, including an entire chapter on NMR theory. This book provides guidance in setting up LC-NMR systems, discussion of LC methods that are compatible with NMR, and an update on recent hardware and software advances for system performance, such as improvements in magnet design, probe technology, and solvent suppression techniques that enable unprecedented mass sensitivity in NMR. It also describes numerous NMR collection strategies, including continuous flow, stop flow, solid phase extraction (SPE), loop collection, and capillary electrophoresis. In addition, the author presents an overview of NMR experiments and techniques used in structure elucidation. The text focuses on current developments in chromatographic-NMR integration, with particular emphasis on utility in the pharmaceutical industry. Applications include trace analysis, analysis of mixtures, and detection of degradation products, impurities, metabolites, peptides, and more. The text discusses novel uses and emerging technologies that challenge detection limits as well future directions for this important technique. This book is a practical primary resource for NMR structure determination—including theory and application—that guides the reader through the steps required for isolation and NMR structure elucidation on the micro scale.