Neurobiology of Alcohol Dependence

• Author : Antonio Noronha,Changhai Cui,Robert Adron Harris,John C. Crabbe
• Publisher : Elsevier
• Release : 02 May 2014

Recent scientific advances have provided substantial information on the brain circuits and pathways relevant to various aspects of dependence. Neurobiology of Alcohol Dependence highlights the most recent data at the molecular, cellular, neurocircuitry, and behavioral levels, fostering an understanding how neuroplasticity and neuroadaptation occur, and how different neural pathways and neurocircuits contribute to dependence. Highlights recent advances in understanding alcohol addiction from molecular, cellular, neurocircuitry, and behavioral levels Integrates several emerging areas of research and discusses the application of novel

• Author : Edith V. Sullivan,Adolf Pfefferbaum
• Publisher : Elsevier
• Release : 08 October 2014

Alcohol is the most widely used drug in the world, yet alcoholism remains a serious addiction affecting nearly 20 million Americans. Our current understanding of alcohol's effect on brain structure and related functional damage is being revolutionized by genetic research, basic neuroscience, brain imaging science, and systematic study of cognitive, sensory, and motor abilities. Volume 125 of the Handbook of Clinical Neurology is a comprehensive, in-depth treatise of studies on alcohol and the brain covering the basic understanding of alcohol's effect on

• Author : Victor R. Preedy
• Publisher : Academic Press
• Release : 19 March 2019

Neuroscience of Alcohol: Mechanisms and Treatment presents the fundamental information necessary for a thorough understanding of the neurobiological underpinnings of alcohol addiction and its effects on the brain. Offering thorough coverage of all aspects of alcohol research, treatment and prevention, and containing contributions from internationally recognized experts, the book provides students, early-career researchers, and investigators at all levels with a fundamental introduction to all aspects of alcohol misuse. Alcohol is one of the world’s most common addictive substances, with

• Author : Edith V. Sullivan
• Publisher : Unknown
• Release : 01 May 2009

Contents: Neurobiology of Alcohol Dependence: Focus on Motivational Mechanisms; Communication Networks in the Brain: Neurons, Receptors, Neurotransmitters, and Alcohol; Translational Studies of Alcoholism: Bridging the Gap; Strategies to Study the Neuroscience of Alcoholism; Positron Emission Tomography as a Tool for Studying Alcohol Abuse; From Event-Related Potential to Oscillations: Genetic Diathesis in Brain (Dys)Function and Alcohol Dependence; The Use of Magnetic Resonance Spectroscopy and Magnetic Resonance Imaging in Alcohol Research; Magnetic Resonance Imaging Approaches for Studying Alcoholism Using Mouse Models;

• Author : National Institute on Alcohol Abuse and Alcoholism (U.S.)
• Publisher : Unknown
• Release : 23 May 2022

"Neuroscience is showing that the pathways of addiction are based in the brain. Using advanced techniques such as imaging methods and studies with animal models, researchers are learning more about how alcohol interacts with the brain's communication system in different people. Innovative technology also is helping identify the changes that occur in the brain's structure and function as a result of drinking, and how alcohol disrupts the brain's delicate chemical balance. This information may help scientists understand why and how

• Author : George F. Koob,Michel Le Moal
• Publisher : Elsevier
• Release : 11 November 2005

Neurobiology of Addiction is conceived as a current survey and synthesis of the most important findings in our understanding of the neurobiological mechanisms of addiction over the past 50 years. The book includes a scholarly introduction, thorough descriptions of animal models of addiction, and separate chapters on the neurobiological mechanisms of addiction for psychostimulants, opioids, alcohol, nicotine and cannabinoids. Key information is provided about the history, sources, and pharmacokinetics and psychopathology of addiction of each drug class, as well as the

• Author : George F. Koob,Michael A. Arends,Mandy McCracken,Michel Le Moal
• Publisher : Academic Press
• Release : 07 July 2021

A current survey and synthesis of the most important findings in our understanding of the neurobiological mechanisms of addiction is detailed in our Neurobiology of Addiction series, each volume addressing a specific area of addiction. ALCOHOL, Volume 3 in the series, explores the molecular, cellular, and neurocircuitry systems in the brain responsible for alcohol addiction using the heuristic three-stage cycle framework of binge/intoxication, withdrawal/negative affect, and preoccupation/anticipation. Outlines the history and behavioral mechanism of action of alcohol relevant

• Author : Antonio Noronha,Michael Eckardt,Kenneth Rabinowitz Warren
• Publisher : Unknown
• Release : 23 May 2022

• Author : Yuan Liu,David M. Lovinger
• Publisher : CRC Press
• Release : 14 February 2002

Neuroscience research in alcohol-related disorders has made remarkable progress in the last two decades. The advances are due, in great part, to the large array of powerful biomedical, bioengineering, and computational biological techniques that are now employed. To date, there has not been a comprehensive text that covers recently develope

• Author : George F. Koob,Michael A. Arends,Mandy L. McCracken,Michel Le Moal
• Publisher : Academic Press
• Release : 11 June 2019

Introduction to Addiction, Volume One in the series, introduces the reader to the study of neurobiology of addiction by clearly defining addiction and its neuroadaptational views. This volume includes thorough descriptions of the various animal models applicable to the study of addiction, including Animal Models of the Binge-Intoxication Stage of the Addiction Cycle and Animal Models of Vulnerability to Addiction. The book's authors also include a section on numerous neurobiological theories that aid in the understanding of addiction, including dopamine,

• Author : Changhai Cui,Lindsey Grandison,Antonio Noronha
• Publisher : Springer Science & Business Media
• Release : 14 November 2012

Recent studies have provided clear evidence on the role of neural-immune interactions in normal brain function and neuropathological conditions. Neuroimmune factors, which play an essential role in neuroinflammatory response, have been implicated in the regulation of neuronal function and plasticity. Thus, neural-immune interactions provide a new frame work for understanding the role of the neuroimmune system in normal brain function, neurodevelopment, and a variety of neurological disorders. These advances have a far reaching impact on many areas of neuroscience, including

• Author : Anonim
• Publisher : Academic Press
• Release : 31 October 2017

The Role of Neuropeptides in Addiction and Disorders of Excessive Consumption, Volume 136 in the International Review of Neurobiology series, provides an overview of the top candidate neuropeptides in the modulation of alcohol and drug abuse, also covering eating disorders and obesity. Topics covered in this latest release include Corticotropin Releasing Factor (CRF) and Addictive Behaviors, Dynorphin/Kappa Opioid Receptor Signaling in Pre-clinical Models of Alcohol, Drug, and Food Addiction, The Role of Ghrelin Signaling in Additive Behaviors, The Role of

• Author : George F. Koob,Michael A. Arends,Michel Le Moal
• Publisher : Academic Press
• Release : 12 July 2014

Drugs, Addiction, and the Brain explores the molecular, cellular, and neurocircuitry systems in the brain that are responsible for drug addiction. Common neurobiological elements are emphasized that provide novel insights into how the brain mediates the acute rewarding effects of drugs of abuse and how it changes during the transition from initial drug use to compulsive drug use and addiction. The book provides a detailed overview of the pathophysiology of the disease. The information provided will be useful for neuroscientists

• Author : Anonim
• Publisher : Unknown
• Release : 23 May 2022

• Author : Victor R. Preedy
• Publisher : Academic Press
• Release : 15 March 2019

Alcohol is one of the world's most common addictive substances, with about 2 billion individuals worldwide consuming it in one form or another and 3 million annual deaths that are associated with alcohol misuse. Alcohol alters a variety of neurological processes, from molecular biology to cognition. Moreover, addiction to alcohol can lead to numerous other health concerns and damage virtually every organ system in the body, making diagnosis and treatment of individuals addicted to alcohol of critical importance. Effective treatments are contingent