Neuropsychiatric Disorders and Epigenetics

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  • Author : Dag Yasui
  • Publisher : Academic Press
  • Pages : 444 pages
  • ISBN : 0128005270
  • Rating : /5 from reviews
CLICK HERE TO GET THIS BOOK >>>Neuropsychiatric Disorders and Epigenetics

Download or Read online Neuropsychiatric Disorders and Epigenetics full in PDF, ePub and kindle. this book written by Dag Yasui and published by Academic Press which was released on 15 November 2016 with total page 444 pages. We cannot guarantee that Neuropsychiatric Disorders and Epigenetics book is available in the library, click Get Book button and read full online book in your kindle, tablet, IPAD, PC or mobile whenever and wherever You Like. Neuropsychiatric Disorders and Epigenetics is a comprehensive reference for the epigenetic basis of most common neuropsychiatric disorders. The volume is organized into chapters representing individual neuropsychiatric disorders, from addition to obesity contributed by leading experts in their respective fields. The epigenetic aspects of each disorder are discussed, in the context of the full range of epigenetic mechanisms including DNA modification, histone post-translational modification, chromatin organization and non-coding RNA. A particular emphasis is placed on potential epigenetic interventions, when the effects of environmental stimuli on epigenetic states is particularly relevant o disease. Recent discoveries in epigenetic research enabled by epic advances in genomic technologies have positioned the field for broad translation to therapeutic interventions for previously unmanageable disorders Neuropsychiatric disorders represent a prime target of epigenetic interventions as they are highly debilitating, often chronic diseases with enormous costs to society. Thus, this volume will help define epigenetics as a key player in neuropsychiatric disorders, highlighting the full spectrum of epigenetic mechanisms underlying such disorders and introducing the vast range of epigenetic therapies under development. Analyzes the effects of environmental stimuli on epigenetic states that correlate with neuropsychiatric disease induction Reviews the epigenetic basis for common neuropsychiatric disorders, thereby guiding translational therapies for clinicians and mechanistic studies for scientists Extensive use of diagrams, illustrations, tables, and graphical abstracts for each section providing rapid assessment

Neuropsychiatric Disorders and Epigenetics

Neuropsychiatric Disorders and Epigenetics
  • Author : Dag Yasui,Jacob Peedicayil,Dennis R. Grayson
  • Publisher : Academic Press
  • Release : 15 November 2016
GET THIS BOOK Neuropsychiatric Disorders and Epigenetics

Neuropsychiatric Disorders and Epigenetics is a comprehensive reference for the epigenetic basis of most common neuropsychiatric disorders. The volume is organized into chapters representing individual neuropsychiatric disorders, from addition to obesity contributed by leading experts in their respective fields. The epigenetic aspects of each disorder are discussed, in the context of the full range of epigenetic mechanisms including DNA modification, histone post-translational modification, chromatin organization and non-coding RNA. A particular emphasis is placed on potential epigenetic interventions, when the effects

Epigenetic Editing to Validate Findings from Methylome wide Association Studies of Neuropsychiatric Disorders

Epigenetic Editing to Validate Findings from Methylome wide Association Studies of Neuropsychiatric Disorders
  • Author : Robin F. Chan
  • Publisher : Unknown
  • Release : 23 October 2021
GET THIS BOOK Epigenetic Editing to Validate Findings from Methylome wide Association Studies of Neuropsychiatric Disorders

DNA methylation is necessary for learning, memory consolidation and has been implicated in a number of neuropsychiatric disorders. Obtaining high quality and comprehensive data for the three common forms of methylation in brain is challenging for methylome-wide association studies (MWAS). To address this we optimized a panel of enrichment methods for screening the brain methylome. Results show that these enrichment techniques approach the coverage and fidelity of the current gold standard bisulfite based techniques. Our MBD-based method can also be

Novel Approaches to Studying Basal Ganglia and Related Neuropsychiatric Disorders

Novel Approaches to Studying Basal Ganglia and Related Neuropsychiatric Disorders
  • Author : XIAO-HONG LU
  • Publisher : Academic Press
  • Release : 06 November 2009
GET THIS BOOK Novel Approaches to Studying Basal Ganglia and Related Neuropsychiatric Disorders

Published since 1959, International Review of Neurobiology is a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews and thematic volumes that focus on recent progress in a specific area of neurobiology research. This volume is a collection of articles covering Novel Approaches to Studying Basal Ganglia and Related Neuropsychiatric Disorders. Topics covered include molecular profiling of direct and indirect striatal

Epigenetic Approaches in Drug Discovery Development and Treatment

Epigenetic Approaches in Drug Discovery  Development and Treatment
  • Author : Shibashish Giri,Chandravanu Dash
  • Publisher : Frontiers Media SA
  • Release : 07 August 2020
GET THIS BOOK Epigenetic Approaches in Drug Discovery Development and Treatment

Establishment of a normal phenotype involves dynamic epigenetic regulation of gene expression that when affected contributes to human diseases. On a molecular level, epigenetic regulation is marked by specific covalent modifications (acetylation, methylation, phosphorylation, sumoylation, PARylation and ubiquitylation) of DNA and its associated histones. Studies also suggest the influence of such epigenetic modifications on non-coding RNA expression implicated in normal and diseased phenotypes. Epigenetic control of genetic expression is a reversible process essential for normal development and function of an

From Early Life Stress to Adult Psychopathology

From Early Life Stress to Adult Psychopathology
  • Author : Helena Palma Gudiel
  • Publisher : Unknown
  • Release : 23 October 2021
GET THIS BOOK From Early Life Stress to Adult Psychopathology

"Psychiatric disorders are highly prevalent and one of the leading causes of disease burden worldwide. Nevertheless, there are no validated biomarkers to be used for either diagnostic or prognostic purposes and their etiology remains largely unknown. Thanks to heritability studies, it has been recognized that both nature (genetics) and nurture (environment) contribute to the onset of mental disorders. Accordingly, exposure to both prenatal stress and childhood maltreatment has been reliably identified as a risk factor for a wide range of

Epigenetic Mechanisms in Development and Disease

Epigenetic Mechanisms in Development and Disease
  • Author : Paul J. Hurd,Adele Murrell,Ian C. Wood
  • Publisher : Unknown
  • Release : 23 October 2021
GET THIS BOOK Epigenetic Mechanisms in Development and Disease

Epigenetic Mechanisms in Development and Disease, the latest volume in the Biochemical Society Symposia series, features ten chapters from the Biochemical Society's Annual Symposium held at the University of Leeds on 11 - 13 December 2012. Epigenetic mechanisms, including the post translational modifications of chromatin (DNA and histones), play pivotal roles in development, cell differentiation and cell identity. Inappropriate regulation of epigenetic mechanisms has been implicated in common human diseases including diabetes, neuropsychiatric disorders and cancers. Environmental influences such as nutrition and stress

Staging Neuropsychiatric Disorders

Staging Neuropsychiatric Disorders
  • Author : Tomás Palomo,Richard Kostrzewa,Richard J. Beninger
  • Publisher : Springer
  • Release : 08 August 2015
GET THIS BOOK Staging Neuropsychiatric Disorders

Book chapters are authored by participants in the International Meeting on Staging Neuropsychiatric Disorders: Implications for Etiopathogenesis and Treatment, held in Mojácar (Almería) Spain from 14-18 October 2009. Chapters are organized into four sections on themes encompassed by Staging Neuropsychiatric Disorders: Clinical Staging in the Pathophysiology of Psychotic and Affective Disorders, Staging Perspectives in Neurodevelopmental Aspects of Neuropsychiatry, Epigenetics and Biomarkers in the Staging of Neuropsychiatric Disorders, and Staging Neurodegenerative Disorders. This volume should serve as a resource for

Epigenetic Regulation in the Nervous System

Epigenetic Regulation in the Nervous System
  • Author : J. David Sweatt,Michael J. Meaney,Eric J. Nestler,Schahram Akbarian
  • Publisher : Academic Press
  • Release : 31 December 2012
GET THIS BOOK Epigenetic Regulation in the Nervous System

Epigenetic Regulation in the Nervous System addresses current understanding of the roles of epigenetic processes at the molecular/cellular level, their impact on neural development and behavior, and the potential roles of these mechanisms in neurological and psychiatric disorders. This award-winning volume spans molecular epigenetics, development, cellular physiology and biochemistry, synaptic and neural plasticity, and behavioral models, and is unique in covering epigenetically based disorders of the central nervous system. Behavioral epigenetics is the study of how environmental factors alter

Chromatin Signaling and Neurological Disorders

Chromatin Signaling and Neurological Disorders
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 24 May 2019
GET THIS BOOK Chromatin Signaling and Neurological Disorders

Chromatin Signaling and Neurological Disorders, Volume Seven, explores our current understanding of how chromatin signaling regulates access to genetic information, and how their aberrant regulation can contribute to neurological disorders. Researchers, students and clinicians will not only gain a strong grounding on the relationship between chromatin signaling and neurological disorders, but they'll also discover approaches to better interpret and employ new diagnostic studies and epigenetic-based therapies. A diverse range of chapters from international experts speaks to the basis of chromatin

Epigenetic Regulation of Astrocytic Dysfunction in Depression and Suicide

Epigenetic Regulation of Astrocytic Dysfunction in Depression and Suicide
  • Author : Corina Nagy
  • Publisher : Unknown
  • Release : 23 October 2021
GET THIS BOOK Epigenetic Regulation of Astrocytic Dysfunction in Depression and Suicide

"Major depressive disorder (MDD) affects close to 1.8 million Canadians (~5% of the population) annually, and is the third most burdensome disease worldwide. Although over 50 years of drug therapy and research has implicated multiple brain regions and systems, our understanding of the pathophysiology of MDD remains incomplete. Research into astrocytic dysfunction in MDD has generated consistent and replicable findings and has been bolstered by our increased understanding of the multiple active roles of astrocytes in normal brain function. Several lines of evidence

Epigenetics and Stress During Early Life

Epigenetics and Stress During Early Life
  • Author : Rose Mary Pinheiro
  • Publisher : Unknown
  • Release : 23 October 2021
GET THIS BOOK Epigenetics and Stress During Early Life

Methods:The PubMed database was searched for the following keywords: u201cearly life stressu201d, u201cearly stress exposureu201d, u201cepigeneticu201d, and u201cpsychiatryu201d. Meta-analyses, reviews, and controlled and randomized clinical trials. Studies that were considered conceptual groundbreakers for this theme were also included, regardless of their publication date. Objectives:Objective e was to review the scientific literature on the association between stress exposure during early life and its consequences on adulthood. Results: Exposure to biopsychosocial stressors

Epigenetics and Neuroplasticity Evidence and Debate

Epigenetics and Neuroplasticity   Evidence and Debate
  • Author : Anonim
  • Publisher : Academic Press
  • Release : 05 November 2014
GET THIS BOOK Epigenetics and Neuroplasticity Evidence and Debate

The ‘epi-(Greek for ‘over’, ‘above’)genome’, with its rich cache of highly regulated, structural modifications—including DNA methylation, histone modifications and histone variants—defines the moldings and three-dimensional structures of the genomic material inside the cell nucleus and serves, literally, as a molecular bridge linking the environment to the genetic materials in our brain cells. Due to technological and scientific advances in the field, the field of neuroepigenetics is currently one of the hottest topics in the basic and