Neuronal Chloride Transporters in Health and Disease

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  • Author : Xin Tang
  • Publisher : Academic Press
  • Pages : 766 pages
  • ISBN : 0128153199
  • Rating : /5 from reviews
CLICK HERE TO GET THIS BOOK >>>Neuronal Chloride Transporters in Health and Disease

Download or Read online Neuronal Chloride Transporters in Health and Disease full in PDF, ePub and kindle. this book written by Xin Tang and published by Academic Press which was released on 19 June 2020 with total page 766 pages. We cannot guarantee that Neuronal Chloride Transporters in Health and Disease book is available in the library, click Get Book button and read full online book in your kindle, tablet, IPAD, PC or mobile whenever and wherever You Like. In the past several years, there has been an exciting body of new research that links impairments in the expression or function of neuronal chloride transporters to a growing number of diseases spanning from autism to brain aging. This book introduces the core concepts and highlights the recent advances in understanding the physiology and pathophysiology of the KCC and NKCC families of neuronal chloride transporters. Neuronal chloride transporter biology is reviewed, including roles in setting the transmembrane chloride gradient and the chloride transport-independent functions, such as regulating excitatory neurotransmission. Chapters are also dedicated to addressing the structure, post-translational modification, membrane trafficking, and protein interaction partners of neuronal chloride transporters, as well as the genetic and environmental factors that regulate their expression in neurons and the novel therapeutic approaches that target neuronal chloride transporters to treat neurological diseases. This new volume will provide readers with an up-to-date summary of the recent advances in neuronal chloride transporter research, with particular emphasis on some of the key emerging topics in the field. Summarizes roles of KCCs and NKCCs in regulating inhibitory and excitatory neurotransmission Reviews the molecular and cellular biology of neuronal chloride transporters Links neuronal chloride transporter deficiencies to autism, epilepsy, depression, and more Identifies role of transporter deficiencies in pain as well as brain and spinal cord injury Discusses drug research targeting neuronal chloride transporters for nervous system diseases

Neuronal Chloride Transporters in Health and Disease

Neuronal Chloride Transporters in Health and Disease
  • Author : Xin Tang
  • Publisher : Academic Press
  • Release : 19 June 2020
GET THIS BOOK Neuronal Chloride Transporters in Health and Disease

In the past several years, there has been an exciting body of new research that links impairments in the expression or function of neuronal chloride transporters to a growing number of diseases spanning from autism to brain aging. This book introduces the core concepts and highlights the recent advances in understanding the physiology and pathophysiology of the KCC and NKCC families of neuronal chloride transporters. Neuronal chloride transporter biology is reviewed, including roles in setting the transmembrane chloride gradient and

Epithelial Anion Transport in Health and Disease

Epithelial Anion Transport in Health and Disease
  • Author : Derek J. Chadwick,Jamie A. Goode
  • Publisher : John Wiley & Sons
  • Release : 11 July 2006
GET THIS BOOK Epithelial Anion Transport in Health and Disease

Cl- absorption and HCO3- secretion are intimately associated processes vital to epithelial function, itself a key physiological activity. Until recently the transporters responsible remained obscure, but a breakthrough occurred with the discovery of the SLC26 transporters family. It is now clear that the SLC26 transporters have broad physiological functions since mutations in several members are linked to a variety of diseases. This book describes the properties of this family in detail, with contributions from the leading global researchers in

Physiology and Pathology of Chloride Transporters and Channels in the Nervous System

Physiology and Pathology of Chloride Transporters and Channels in the Nervous System
  • Author : F. Javier Alvarez-Leefmans,Eric Delpire
  • Publisher : Academic Press
  • Release : 22 August 2009
GET THIS BOOK Physiology and Pathology of Chloride Transporters and Channels in the Nervous System

The importance of chloride ions in cell physiology has not been fully recognized until recently, in spite of the fact that chloride (Cl-), together with bicarbonate, is the most abundant free anion in animal cells, and performs or determines fundamental biological functions in all tissues. For many years it was thought that Cl- was distributed in thermodynamic equilibrium across the plasma membrane of most cells. Research carried out during the last couple of decades has led to a dramatic change

The Blood Brain Barrier in Health and Disease Volume One

The Blood Brain Barrier in Health and Disease  Volume One
  • Author : Katerina Dorovini-Zis
  • Publisher : CRC Press
  • Release : 23 June 2015
GET THIS BOOK The Blood Brain Barrier in Health and Disease Volume One

Located at the interface between blood and the brain, the blood-brain barrier is a dynamic permeability barrier formed by a continuous layer of specialized endothelial cells endowed with important permeability, transport, and regulatory functions that both protect the internal milieu of the brain and allow essential nutrients to be transported into the brain. Over the last 25 years, we have witnessed remarkable expansion of our knowledge of the structure, biology, and function of the cerebral endothelium. In The Blood-Brain Barrier in

Issues in Clinical Epileptology A View from the Bench

Issues in Clinical Epileptology  A View from the Bench
  • Author : Helen E. Scharfman,Paul S. Buckmaster
  • Publisher : Springer
  • Release : 10 July 2014
GET THIS BOOK Issues in Clinical Epileptology A View from the Bench

This book is dedicated to Dr. Philip A. Schwartzkroin. The book has a novel format because it is not intended to be a set of reviews. Instead, it is an effort to explore important topics in the epilepsy research field. Because articles are written by leaders in the field who have years of experience and individuals with diverse expertise, articles are likely to have a long-lasting impact and be relevant for both epileptologists and neuroscientists. Authors address topics that are

Gasotransmitters novel regulators of ion channels and transporters

Gasotransmitters  novel regulators of ion channels and transporters
  • Author : Wolfgang G. Clauss
  • Publisher : Frontiers E-books
  • Release : 23 April 2013
GET THIS BOOK Gasotransmitters novel regulators of ion channels and transporters

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Nonclassical Ion Channels in the Nervous System

Nonclassical Ion Channels in the Nervous System
  • Author : Xu Tian-le,Long-Jun Wu
  • Publisher : CRC Press
  • Release : 05 August 2021
GET THIS BOOK Nonclassical Ion Channels in the Nervous System

Ion channels generate bioelectricity. Recent findings have documented the biophysical properties, the structure, assembly and regulation, and function and dysfunction of nonclassical nervous system ion channels. This book reviews nonclassical ion channel research, ranging from the basic biology, structure, regulations to their functions not only in normal physiology but also neurological disorders, using a variety of cutting-edge techniques and novel animal models.

The Control of Food and Fluid Intake in Health and Disease

The Control of Food and Fluid Intake in Health and Disease
  • Author : Michael J. G. Farthing,Dilip Mahalanabis
  • Publisher : Lippincott Raven
  • Release : 30 September 2022
GET THIS BOOK The Control of Food and Fluid Intake in Health and Disease

Written by an international group of noted scientists and clinicians, this volume examines the latest findings on the control of nutritional and fluid balance in health and in various disease states. The contributors provide new insights into the role of the brain and gut in regulating nutrient intake, the mechanisms by which fluid homeostasis is disturbed in disease, and the pathogenesis and treatment of acute and chronic diarrhea, dehydration, anorexia, and obesity. Coverage includes discussions of recent developments in oral