Neuronal and Synaptic Dysfunction in Autism Spectrum Disorder and Intellectual Disability

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  • Author : Carlo Sala
  • Publisher : Academic Press
  • Pages : 394 pages
  • ISBN : 0128005335
  • Rating : /5 from reviews
CLICK HERE TO GET THIS BOOK >>>Neuronal and Synaptic Dysfunction in Autism Spectrum Disorder and Intellectual Disability

Download or Read online Neuronal and Synaptic Dysfunction in Autism Spectrum Disorder and Intellectual Disability full in PDF, ePub and kindle. this book written by Carlo Sala and published by Academic Press which was released on 30 April 2016 with total page 394 pages. We cannot guarantee that Neuronal and Synaptic Dysfunction in Autism Spectrum Disorder and Intellectual Disability book is available in the library, click Get Book button and read full online book in your kindle, tablet, IPAD, PC or mobile whenever and wherever You Like. Neuronal and Synaptic Dysfunction in Autism Spectrum Disorder and Intellectual Disability provides the latest information on Autism spectrum disorders (ASDs), the lifelong neurodevelopmental disorders that present in early childhood and affect how individuals communicate and relate to others and their surroundings. In addition, three quarters of ASD patients also manifest severe intellectual disability. Though certain genes have been implicated, ASDs remain largely a mystery, and research looking into causes and cellular deficits are crucial for better understanding of neurodevelopmental disorders. Despite the prevalence and insidious nature of this disorder, this book remains to be an extensive resource of information and background on the state of current research in the field. The book serves as a reference for this purpose, and discusses the crucial role synaptic activity plays in proper brain function. In addition, the volume discusses the neurodevelopmental synaptopathies and serves as a resource for scientists and clinicians in all biomedical science specialties. This research has been crucial for recent studies that have provided a rationale for the development of pharmacological agents able to counteract functional synaptic anomalies and potentially ameliorate some ASD symptoms. Introduces the genetic and non-genetic causes of autism and associated intellectual disabilities Describes the genes implicated in autistic spectrum disorders and their function Considers major individual genetic causes of autism, Rett syndrome, Fragile X syndrome, and other autism spectrum disorders, as well as their classification as synaptopathies Presents a thorough discussion of the clinical aspects of multiple neurodevelopmental disorders and the experimental models that exist to study their pathophysiology in vitro and in vivo, including animal models and patient-derived stem cell culture

Neuronal and Synaptic Dysfunction in Autism Spectrum Disorder and Intellectual Disability

Neuronal and Synaptic Dysfunction in Autism Spectrum Disorder and Intellectual Disability
  • Author : Carlo Sala,Chiara Verpelli
  • Publisher : Academic Press
  • Release : 30 April 2016
GET THIS BOOK Neuronal and Synaptic Dysfunction in Autism Spectrum Disorder and Intellectual Disability

Neuronal and Synaptic Dysfunction in Autism Spectrum Disorder and Intellectual Disability provides the latest information on Autism spectrum disorders (ASDs), the lifelong neurodevelopmental disorders that present in early childhood and affect how individuals communicate and relate to others and their surroundings. In addition, three quarters of ASD patients also manifest severe intellectual disability. Though certain genes have been implicated, ASDs remain largely a mystery, and research looking into causes and cellular deficits are crucial for better understanding of neurodevelopmental disorders.

Neural and Synaptic Defects in Autism Spectrum Disorders

Neural and Synaptic Defects in Autism Spectrum Disorders
  • Author : Hansen Wang,Laurie C. Doering
  • Publisher : Frontiers Media SA
  • Release : 07 July 2015
GET THIS BOOK Neural and Synaptic Defects in Autism Spectrum Disorders

Autism spectrum disorders (ASDs) are a group of genetically and clinically heterogeneous neurodevelopmental disorders characterized by impaired reciprocal social interactions and communication, and restricted and repetitive patterns of behaviors and interests. Studies in genetics, neurobiology and systems biology are providing insights into the pathogenesis of ASDs. Investigation of neural and synaptic defects in ASDs not only sheds light on the molecular and cellular mechanisms that govern the function of the central nervous system, but may lead to the discovery of

Autism

Autism
  • Author : Michael Fitzgerald,Jane Yip
  • Publisher : BoD – Books on Demand
  • Release : 12 April 2017
GET THIS BOOK Autism

This book opens with a discussion of neurodiversity and an elaboration of the diagnosis of autism. It then examines factors correlating with autism, including sex bias, month of birth, migration and impact of infant feeding. The next section is on the impact of autism. The neurobiology and genetic section deals with epigenetics and intracellular pathways associated with etiology. The development and behaviour section deals with proprioceptive profiles and joint attention in autism. The final section focuses on interventions including mindfulness,

Neuronal Stress Pathways Influence Synaptic Development and Nervous System Function in Drosophila Melanogaster

Neuronal Stress Pathways Influence Synaptic Development and Nervous System Function in Drosophila Melanogaster
  • Author : Alexandra Russo
  • Publisher : Unknown
  • Release : 14 August 2022
GET THIS BOOK Neuronal Stress Pathways Influence Synaptic Development and Nervous System Function in Drosophila Melanogaster

Synaptic development is a complex and highly orchestrated process in which the nervous system must build appropriately sized and sufficiently strong connections between neurons and their targets. Many neurodevelopmental disorders are caused by dysregulation of the mechanisms that promote the formation of normal synaptic connections. Here, I show that dysregulation of neuronal stress pathways during development negatively impacts synaptic growth and functionality. First, I explore the Drosophila model of Fragile X Syndrome, a common and debilitating disorder that causes intellectual

Autism Spectrum Disorders From Genotypes to Phenotypes

Autism Spectrum Disorders  From Genotypes to Phenotypes
  • Author : Valsamma Eapen,Andrew J. Whitehouse,Charles Claudianos,Rudi Crncec
  • Publisher : Frontiers Media SA
  • Release : 10 December 2015
GET THIS BOOK Autism Spectrum Disorders From Genotypes to Phenotypes

This Research Topic covers the pathogenetic processes in Autism Spectrum Disorder (ASD) that underpin the translation of genetic vulnerability to clinically significant symptoms. Available research data in ASD suggests that it is a neural connectivity disorder and that the social communication and related neurobehavioural symptoms result from reduced synchronization between key "social brain" regions. These interconnected neural systems can be understood through the relationship between functionally relevant anatomic areas and neurochemical pathways, the programming of which are genetically modulated during

The Neuroscience of Autism Spectrum Disorders

The Neuroscience of Autism Spectrum Disorders
  • Author : Joseph D. Buxbaum,Patrick R. Hof
  • Publisher : Academic Press
  • Release : 31 December 2012
GET THIS BOOK The Neuroscience of Autism Spectrum Disorders

Autism is no longer considered a rare disease, and the Center for Disease Control now estimates that upwards of 730,000 children in the US struggle with this isolating brain disorder. New research is leading to greater understanding of and ability to treat the disorder at an earlier age. It is hoped that further genetic and imaging studies will lead to biologically based diagnostic techniques that could help speed detection and allow early, more effective intervention. Edited by two leaders in the

Translational Anatomy and Cell Biology of Autism Spectrum Disorder

Translational Anatomy and Cell Biology of Autism Spectrum Disorder
  • Author : Michael J. Schmeisser,Tobias M. Boeckers
  • Publisher : Springer
  • Release : 25 May 2017
GET THIS BOOK Translational Anatomy and Cell Biology of Autism Spectrum Disorder

Autism spectrum disorder (ASD) affects approximately 1 % of the human population and is characterized by a core symptomatology including deficits in social interaction and repetitive patterns of behaviour plus various co-morbidities. Although a lot of progress has been made to uncover underlying causes and mechanisms throughout the last decade, we are still at the very beginning to understand this enormously complex neurodevelopmental condition. This special volume is focused on translational anatomy and cell biology of ASD. International experts from the field

Homeostatic and Retrograde Signaling Mechanisms Modulating Presynaptic Function and Plasticity

Homeostatic and Retrograde Signaling Mechanisms Modulating Presynaptic Function and Plasticity
  • Author : Michael A. Sutton,Dion Dickman
  • Publisher : Frontiers Media SA
  • Release : 06 January 2016
GET THIS BOOK Homeostatic and Retrograde Signaling Mechanisms Modulating Presynaptic Function and Plasticity

Activity within neural circuits shapes the synaptic properties of component neurons in a manner that maintains stable excitatory drive, a process referred to as homeostatic plasticity. These potent and adaptive mechanisms have been demonstrated to modulate activity at the level of an individual neuron, synapse, circuit, or entire network, and dysregulation at some or all of these levels may contribute to neuropsychiatric disorders, intellectual disability, and epilepsy. Greater mechanistic understanding of homeostatic plasticity will provide key insights into the etiology

Biometals in Autism Spectrum Disorders

Biometals in Autism Spectrum Disorders
  • Author : Andreas Grabrucker
  • Publisher : Academic Press
  • Release : 08 July 2020
GET THIS BOOK Biometals in Autism Spectrum Disorders

Biometals in Autism Spectrum Disorders focuses on trace metals and autism. Compared to other references examining ASDs or metallomics, this book presents findings of abnormal metal homeostasis in ASD, providing an overview of current findings on trace metal biology, its role in ASD etiology, and how abnormal trace metal biology may be a common factor of several genetic and non-genetic causes of ASDs that were once considered unrelated. This comprehensive resource opens new vistas for the development of new therapies

Cassidy and Allanson s Management of Genetic Syndromes

Cassidy and Allanson s Management of Genetic Syndromes
  • Author : John C. Carey,Suzanne B. Cassidy,Agatino Battaglia,David Viskochil
  • Publisher : John Wiley & Sons
  • Release : 27 January 2021
GET THIS BOOK Cassidy and Allanson s Management of Genetic Syndromes

The most recent update to one of the most essential references on medical genetics Cassidy and Allanson's Management of Genetic Syndromes, 4th Edition is the latest version of a classic text in medical genetics. With newly covered disorders and cutting-edge, up-to-date information, this resource remains the most crucial reference on the management of genetic syndromes for students, clinicians, and researchers in the field of medical genetics. The 4th edition includes current information on the identification of genetic syndromes (including newly