Nervous System Drug Delivery

Produk Detail:
  • Author : Russell R. Lonser
  • Publisher : Academic Press
  • Pages : 556 pages
  • ISBN : 0128139986
  • Rating : /5 from reviews
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Download or Read online Nervous System Drug Delivery full in PDF, ePub and kindle. this book written by Russell R. Lonser and published by Academic Press which was released on 25 June 2019 with total page 556 pages. We cannot guarantee that Nervous System Drug Delivery book is available in the library, click Get Book button and read full online book in your kindle, tablet, IPAD, PC or mobile whenever and wherever You Like. Nervous System Drug Delivery: Principles and Practice helps users understand the nervous system physiology affecting drug delivery, the principles that underlie various drug delivery methods, and the appropriate application of drug delivery methods for drug- and disease-specific treatments. Researchers developing nervous system putative therapeutic agents will use this book to optimize drug delivery during preclinical assessment and to prepare for regulatory advancement of new agents. Clinicians will gain direct insights into pathophysiologic alterations that impact drug delivery and students and trainees will find this a critical resource for understanding and applying nervous system drug delivery techniques. Offers an up-to-date, comprehensive resource on drug delivery to the nervous system Provides a bridge for understanding across nervous system delivery-related physiology, drug delivery principles. and the methodologies that underlie the various methods of drug distribution (with clinical application) Written for a broad audience of researchers, clinicians and advanced graduate students in neuroscience, neurology, neurosurgery, pharmacology, radiology and psychiatry

Drug Delivery to the Central Nervous System

Drug Delivery to the Central Nervous System
  • Author : Kewal K. Jain
  • Publisher : Humana
  • Release : 23 August 2016
GET THIS BOOK Drug Delivery to the Central Nervous System

Playing an important role in the treatment of neurological disorders, the delivery of drugs to central nervous system (CNS), both administered directly and administered systematically for targeted action, encounters a major challenge in the form of the blood-brain barrier (BBB), which limits the access of drugs to the brain substance. In Drug Delivery to the Central Nervous System, experts in the field present essential methods used to deliver therapeutics across the BBB, both in experimental animals and in humans. In

Nervous System Drug Delivery

Nervous System Drug Delivery
  • Author : Russell R. Lonser,Malisa Sarntinoranont,Kristof Bankiewicz
  • Publisher : Academic Press
  • Release : 25 June 2019
GET THIS BOOK Nervous System Drug Delivery

Nervous System Drug Delivery: Principles and Practice helps users understand the nervous system physiology affecting drug delivery, the principles that underlie various drug delivery methods, and the appropriate application of drug delivery methods for drug- and disease-specific treatments. Researchers developing nervous system putative therapeutic agents will use this book to optimize drug delivery during preclinical assessment and to prepare for regulatory advancement of new agents. Clinicians will gain direct insights into pathophysiologic alterations that impact drug delivery and students and

Nanomedicines for Brain Drug Delivery

Nanomedicines for Brain Drug Delivery
  • Author : Javier O. Morales,Pieter J. Gaillard
  • Publisher : Humana
  • Release : 20 November 2020
GET THIS BOOK Nanomedicines for Brain Drug Delivery

This volume explores the latest research in central nervous system (CNS) targeted nanocarriers, methods for their synthesis, and its characterization process. Chapters in this book cover topics such as polymeric nanoparticles and liposomes; self-assembled peptide-based scaffolds for lesions of the nervous system; use of peptides as CNS drugs and as potential carriers to optimize brain-targeted delivery; ways to model and assess blood brain barrier absorption of drugs; and the role of neurodegeneration progress of nanomaterials and their potential toxicity concerns.

Drug and Gene Delivery to the Central Nervous System for Neuroprotection

Drug and Gene Delivery to the Central Nervous System for Neuroprotection
  • Author : Hari S. Sharma,Dafin F. Muresanu,Aruna Sharma
  • Publisher : Springer
  • Release : 05 June 2017
GET THIS BOOK Drug and Gene Delivery to the Central Nervous System for Neuroprotection

This book summarizes the latest research on drug and gene delivery to the central nervous system (CNS). The chapters address safety concerns regarding the nanotechnology that is needed to develop nanomedicine for clinical practice. Particular focus is given to new technologies that have emerged in recent years to deliver therapeutic materials, such as genes, drugs, and other agents using nanotechnologies of diverse origin. This is an ideal book for students, teachers, researchers, and clinicians interested in a deeper understanding of

Drug Delivery to the Brain

Drug Delivery to the Brain
  • Author : Margareta Hammarlund-Udenaes,Elizabeth C.M. de Lange,Robert G. Thorne
  • Publisher : Springer Science & Business Media
  • Release : 03 December 2013
GET THIS BOOK Drug Delivery to the Brain

The development of new CNS drugs is notoriously difficult. Drugs must reach CNS target sites for action and these sites are protected by a number of barriers, the most important being the blood –brain barrier (BBB). Many factors are therefore critical to consider for CNS drug delivery, e.g. active/passive transport across the BBB, intra-brain distribution, and central/systemic pharmacokinetics, to name a few. Neurological disease and trauma conditions add further complexity because CNS barriers, drug distribution and pharmacokinetics

Liposomal Drug Delivery to the Central Nervous System

Liposomal Drug Delivery to the Central Nervous System
  • Author : Rita Nieto Montesinos
  • Publisher : Unknown
  • Release : 24 June 2021
GET THIS BOOK Liposomal Drug Delivery to the Central Nervous System

Central nervous system diseases represent a huge world of burden of human suffering with negative economic results. Most therapeutic compounds cannot attain the brain because of the blood-brain barrier and its expression of efflux transporters. Among them, the P-glycoprotein plays a significant role leading to failure of various clinical treatments. A non-invasive strategy to circumvent the blood-brain barrier and P-glycoprotein emphasizes on the encapsulation and therefore masking of therapeutic compounds in drug delivery systems. Up to now, liposomes are the

Peptide Transport and Delivery into the Central Nervous System

Peptide Transport and Delivery into the Central Nervous System
  • Author : Laszlo Prokai,Katalin Prokai-Tatrai
  • Publisher : Birkhäuser
  • Release : 06 December 2012
GET THIS BOOK Peptide Transport and Delivery into the Central Nervous System

Hypo- or hypersecretion, alteration in storage, release, catabolism, and post-translational processing of neuropeptides are associated with the etiology of many diseases affecting the central nervous system (CNS). Various peptides native to the brain and the spinal cord, as well as various synthetic peptides, peptide analogues and peptidomimetics developed as their agonists or antagonists could be useful in the treatment of these CNS maladies. However, peptides face a formidable obstacle in reaching the intended site of action due to the existence

Therapeutic Intranasal Delivery for Stroke and Neurological Disorders

Therapeutic Intranasal Delivery for Stroke and Neurological Disorders
  • Author : Jun Chen,Jian Wang,Ling Wei,John H. Zhang
  • Publisher : Springer
  • Release : 29 July 2019
GET THIS BOOK Therapeutic Intranasal Delivery for Stroke and Neurological Disorders

The blood-brain-barrier serves to encapsulate and protect the central nervous system, but it also presents a major barricade to therapeutic drug delivery. Poor penetration is the most common hurdle to translating a promising experimental therapy that uses invasive delivery methods to a clinically useful application. In the last 10 years, intranasal delivery of various therapeutic compounds including small chemicals, large proteins, and even stem cells has proven to be very effective in bypassing the blood-brain-barrier and has led to some important

The Blood Brain Barrier and Drug Delivery to the CNS

The Blood Brain Barrier and Drug Delivery to the CNS
  • Author : Michael Bradbury,David Begley,Jorg Kreuter
  • Publisher : CRC Press
  • Release : 16 May 2000
GET THIS BOOK The Blood Brain Barrier and Drug Delivery to the CNS

This timely and compact monograph addresses how to determine drug permeability across the blood-brain barrier more effectively. Focusing on the physiological mechanisms that influence the passage of agents into the brain, the book covers the latest research on the blood-brain barrier, the current problems of and solutions to drug delivery to the central nervous system (CNS), existing strategies, and prospects for future research. Avoid excessive in vivo experimentation and utilize timesaving in vitro techniques. A concise reference with reviews from

The Blood brain Barrier and Drug Delivery to the Cns

The Blood brain Barrier and Drug Delivery to the Cns
  • Author : Michael Bradbury,Jorg Kreuter,David Begley
  • Publisher : CRC Press
  • Release : 30 August 2019
GET THIS BOOK The Blood brain Barrier and Drug Delivery to the Cns

This timely and compact monograph addresses how to determine drug permeability across the blood-brain barrier more effectively. Focusing on the physiological mechanisms that influence the passage of agents into the brain, the book covers the latest research on the blood-brain barrier, the current problems of and solutions to drug delivery to the central nervous system (CNS), existing strategies, and prospects for future research. Avoid excessive in vivo experimentation and utilize timesaving in vitro techniques. A concise reference with reviews from

Blood Brain Barrier

Blood Brain Barrier
  • Author : David Kobiler,Shlomo Lustig,Shlomo Shapira
  • Publisher : Springer Science & Business Media
  • Release : 06 December 2012
GET THIS BOOK Blood Brain Barrier

The vasculature of the central nervous system (eNS) is characterized by the existence of the blood-brain barrier (BBB), which can be regarded as both an anatomical and physiological phenomenon. The BBB is formed by a complex cellular system of endothelial cells, astroglia, pericytes, perivascular macrophages and a basal membrane, although the anatomic substrate of the BBB is the interendothelial tight junctions that form a continuous sealing. The BBB serves as an exquisitely controlled, functional gate to the eNS. It not

Nanoparticles for Brain Drug Delivery

Nanoparticles for Brain Drug Delivery
  • Author : Carla Vitorino,Andreia Jorge,Alberto A. C. C. Pais
  • Publisher : Jenny Stanford Publishing
  • Release : 28 January 2021
GET THIS BOOK Nanoparticles for Brain Drug Delivery

In an era wherein nanotechnology has sparked a huge research interest, brain drug delivery is not an exception. Aiming at fighting several central nervous system (CNS) conditions, tailored nanoparticles open new avenues to address several challenges in the fields of drug delivery and brain targeting. This book gathers contributions from experts in different, complementary fields, having in common their interest in developing new strategies for brain delivery based on nanotechnologies. The book encompasses general aspects pertaining to fundamental development, including