Natural Killer Cells

• Author : Michael T. Lotze,Angus W. Thomson
• Publisher : Academic Press
• Release : 12 November 2009

Natural Killer Cells explains the importance of killer cells and how they are produced. It mentions that the most likely explanation for killer cell production is that they serve as a complementary system for T cells as a primary defense against viruses. However, these cells defend against certain viruses only, such as herpes viruses and influenza viruses. The book also explains the primary functions of killer cells, and it discusses how these cells help recognize damaged tissues, limit further damage

• Author : Jacques Zimmer
• Publisher : Springer Science & Business Media
• Release : 12 January 2010

Natural killer (NK) cells have been at the forefront of immunology for two decades. During that time, a great amount of information about these cells has been obtained. They are important in antiinfectious and antitumoral defense and shape the adaptive immune response. In addition, they can act as immunoregulatory cells. In recent years, the therapeutic potential of NK cells in cancer immunotherapy has become increasingly evident. This book describes in detail current knowledge about NK cells and covers a broad

• Author : Mourad Aribi
• Publisher : BoD – Books on Demand
• Release : 13 December 2017

The book Natural Killer Cells is the result of a collective work that addresses in a clear and comprehensive way for readers and through as many sensuous details as possible, the most and various fundamental aspects of natural killer cells, as well as their clinical applications in cancer immunotherapy. This book will serve as an invaluable resource and pedagogical support for clinicians, researchers, basic scientists, immunology and immunopathology lecturers, as well as for students in biology and medicine, especially the

• Author : Chiara Romagnani,Joseph C. Sun,Marco Colonna
• Publisher : Frontiers Media SA
• Release : 16 July 2018

Natural Killer (NK) cells are innate lymphocytes, now recognized as members of a larger family of “Innate lymphoid cells” (ILCs). Both murine and human NK cells are well characterized effector cells with cytotoxic as well as cytokine production ability which mainly react in response to microbial and cell stress stimuli, thus playing a central role in the defense against pathogen infection, in tumor surveillance and in regulating immune homeostasis. Despite these established concepts, our understanding of the complexity of NK

• Author : Eva Lotzova,Ronald B. Herberman
• Publisher : CRC Press
• Release : 23 July 2019

First published in 1986: This book contributes to the advancing knowledge of reads in the field of NK cells, and will be helpful as a teaching device.

• Author : Srinivas S. Somanchi
• Publisher : Methods in Molecular Biology
• Release : 27 May 2018

• Author : Stephanie Jost,R. Keith Reeves,Stephen Noel Waggoner
• Publisher : Frontiers Media SA
• Release : 15 December 2020

• Author : Andreas Diefenbach
• Publisher : Elsevier Inc. Chapters
• Release : 06 August 2013

Natural killer (NK) cells are granular lymphocytes that play important roles in immunity against viruses and in the immune surveillance of tumors. In addition to being a potent innate source of IFN-γ, NK cells hold cytoplasmic granula that contain perforin and granzymes involved in cell-mediated cytotoxicity. NK cells express various types of immunoreceptors that are all designed to sense pathological changes of self cells. NK cells differ from lymphocytes of the adaptive immune system, such as T and B cells,

• Author : Massimo Vitale,Simona Sivori,Michael A. Caligiuri
• Publisher : Frontiers Media SA
• Release : 24 March 2020

• Author : Sigurd J. Normann
• Publisher : Springer Science & Business Media
• Release : 06 December 2012

This book is the outcome of a meeting held in Davos, Switzerland, February 7-12, 1982 focused primarily on mononuclear phagocytes and on natural killer (NK) cells. This IX International RES Congress was attended by 489 scientists from 31 countries and there were 340 scientific presentations in oral or poster session. The essential purpose of the Congress was to bring together scientists representing various aspects of mononuclear phagocyte biology to review and examine cri~ically the effects and mechanisms of macrophage growth control as well

• Author : Yui Harada
• Publisher : Unknown
• Release : 15 August 2022

Natural killer (NK) cells are an essential component of the innate immune system, and they play a crucial role in immunity against malignancies. Recent advances in our understanding of NK cell biology have paved the way for new therapeutic strategies based on NK cells for the treatment of various cancers. In this section, we will focus on NK cell immunotherapy, including the enhancement of antibody-dependent cellular cytotoxicity, the manipulation of receptor-mediated activation, inclusion criteria based on killer cell immunoglobulin-like receptor (

• Author : Reinhold E. Schmidt
• Publisher : S Karger Ag
• Release : 15 August 1990

• Author : Magnus Gidlund
• Publisher : Unknown
• Release : 15 August 1980

• Author : Noriko Shimasaki
• Publisher : Humana
• Release : 15 April 2022

This detailed book provides a broad collection of methodologies for natural killer (NK) cell research. Beginning with an assortment of methods for the isolation of NK cells and NK cell differentiation, the volume continues with methodologies for functional tests, such as cytotoxicity, viral infection, and metabolism assays, as well as clinical applications of NK cells. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step,

• Author : Claire E. Lewis,James O'Donnell McGee
• Publisher : Oxford University Press
• Release : 15 August 1992

The ability of an organism to combat infection by foreign particles and microbial pathogens is essential for its survival and evolutionary success. Such efforts at immunity can take two forms. A considerable number of works have been published which focus on the central role of antigen recognition and antibody structure and function in the host response to infection. This volume, however, discusses the recent shift in focus towards the "natural" or "innate" immune system which consists of various cell types