Molecular Evolutionary Models in Drug Discovery

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  • Author : Juan Bueno
  • Publisher : Academic Press
  • Pages : 192 pages
  • ISBN : 0128189290
  • Rating : /5 from reviews
CLICK HERE TO GET THIS BOOK >>>Molecular Evolutionary Models in Drug Discovery

Download or Read online Molecular Evolutionary Models in Drug Discovery full in PDF, ePub and kindle. this book written by Juan Bueno and published by Academic Press which was released on 22 January 2020 with total page 192 pages. We cannot guarantee that Molecular Evolutionary Models in Drug Discovery book is available in the library, click Get Book button and read full online book in your kindle, tablet, IPAD, PC or mobile whenever and wherever You Like. Molecular Evolutionary Models in Drug Discovery explores the application of evolutionary molecular models in drug discovery in which secondary metabolites play a fundamental role. Secondary metabolites are not produced in isolation, they are the result of the interaction of genes, metabolism and the environment. The book examines the role of secondary metabolites as leads in drug discovery and on the development of a rational bioprospecting model for new medicines based on the evolution of secondary metabolism. These evolutionary models are part of biological systems and are the most reliable expression of the functioning of living beings. Examines the integration and application of evolutionary models in the pharmaceutical industry to create new drug development platforms Investigates the biotechnological prospecting of secondary metabolites and their potential use in the discovery of new drugs Evaluates the ecosystem of living beings and how its molecular adaptation might improve the success of therapies

Molecular Evolutionary Models in Drug Discovery

Molecular Evolutionary Models in Drug Discovery
  • Author : Juan Bueno
  • Publisher : Academic Press
  • Release : 22 January 2020
GET THIS BOOK Molecular Evolutionary Models in Drug Discovery

Molecular Evolutionary Models in Drug Discovery explores the application of evolutionary molecular models in drug discovery in which secondary metabolites play a fundamental role. Secondary metabolites are not produced in isolation, they are the result of the interaction of genes, metabolism and the environment. The book examines the role of secondary metabolites as leads in drug discovery and on the development of a rational bioprospecting model for new medicines based on the evolution of secondary metabolism. These evolutionary models are

Preclinical Evaluation of Antimicrobial Nanodrugs

Preclinical Evaluation of Antimicrobial Nanodrugs
  • Author : Juan Bueno
  • Publisher : Springer Nature
  • Release : 08 May 2020
GET THIS BOOK Preclinical Evaluation of Antimicrobial Nanodrugs

Translational medicine addresses the gap between research and the clinical application of new discoveries. To efficiently deliver new drugs to care centers, a preclinical evaluation, both in vitro and in vivo, is required to ensure that the most active and least toxic compounds are selected as well as to predict clinical outcome. Antimicrobial nanomedicines have been shown to have higher specificity in their therapeutic targets and the ability to serve as adjuvants, increasing the effectiveness of pre-existing immune compounds. The

Adaptive Systems in Drug Design

Adaptive Systems in Drug Design
  • Author : Gisbert Schneider
  • Publisher : CRC Press
  • Release : 01 October 2002
GET THIS BOOK Adaptive Systems in Drug Design

A brief history of drug design presented to make clear that there are fashions in this important field and that they change rather rapidly. This is due in part to the fact that the way that a new paradigm is accepted in a drug company often does not depend on its scientific merit alone.

Protein Protein and Domain Domain Interactions

Protein Protein and Domain Domain Interactions
  • Author : Pandjassarame Kangueane,Christina Nilofer
  • Publisher : Springer
  • Release : 16 February 2018
GET THIS BOOK Protein Protein and Domain Domain Interactions

This book illustrates the importance and significance of the molecular (physical and chemical) and evolutionary (gene fusion) principles of protein-protein and domain-domain interactions towards the understanding of cell division, disease mechanism and target definition in drug discovery. It describes the complex issues associated with this phenomenon using cutting edge advancement in Bioinformatics and Bioinformation Discovery. The chapters provide current information pertaining to the types of protein-protein complexes (homodimers, heterodimers, multimer complexes) in context with various specific and sensitive biological functions.

Comprehensive medicinal chemistry II

Comprehensive medicinal chemistry II
  • Author : John B. Taylor,D. J. Triggle
  • Publisher : Elsevier Science Ltd
  • Release : 21 June 2021
GET THIS BOOK Comprehensive medicinal chemistry II

The first edition of Comprehensive Medicinal Chemistry was published in 1990 and very well received. Comprehensive Medicinal Chemistry II is much more than a simple updating of the contents of the first edition. Completely revised and expanded, this new edition has been refocused to reflect the significant developments and changes over the past decade in genomics, proteomics, bioinformatics, combinatorial chemistry, high-throughput screening and pharmacology, and more. The content comprises the most up-to-date, authoritative and comprehensive reference text on contemporary medicinal chemistry

Model Organisms in Drug Discovery

Model Organisms in Drug Discovery
  • Author : Pamela M. Carroll,Kevin Fitzgerald
  • Publisher : John Wiley & Sons
  • Release : 21 November 2003
GET THIS BOOK Model Organisms in Drug Discovery

Fruit flies are "little people with wings" goes the saying in the scientific community, ever since the completion of the Human Genome Project and its revelations about the similarity amongst the genomes of different organisms. It is humbling that most signalling pathways which "define" humans are conserved in Drosophila, the common fruit fly. Feed a fruit fly caffeine and it has trouble falling asleep; feed it antihistamines and it cannot stay awake. A C. elegans worm placed on the antidepressant

Computational Structure based Methods to Anticipate HIV Drug Resistance Evolution and Accelerate Inhibitor Discovery

Computational Structure based Methods to Anticipate HIV Drug Resistance Evolution and Accelerate Inhibitor Discovery
  • Author : Anonim
  • Publisher : Unknown
  • Release : 21 June 2021
GET THIS BOOK Computational Structure based Methods to Anticipate HIV Drug Resistance Evolution and Accelerate Inhibitor Discovery

The evolution of drug resistance in HIV has been a major obstacle in combating the AIDS epidemic, and development of the next generation of antiviral drugs will depend on improvements in the methodology addressing resistance. This work examines HIV evolution from a structural perspective, focusing on the development of methods to anticipate drug resistance and improve drug discovery efforts. To understand the evolution of HIV in the presence of inhibitors requires knowledge of viral replication capacity as well as drug

Successful Drug Discovery

Successful Drug Discovery
  • Author : János Fischer,Christian Klein,Wayne E. Childers
  • Publisher : John Wiley & Sons
  • Release : 07 October 2019
GET THIS BOOK Successful Drug Discovery

Provides unique insider insight into the current drug development process, and what it takes to achieve success In this fourth volume in the series, inventors and primary developers of drugs that made it to the market continue telling the story of the drugs? discovery and development, and discuss the sometimes twisted route from the first drug candidate molecule to the final marketed one. Beginning with a general section addressing overarching topics for drug discovery, the book offers seven chapters that

Molecular Genetic Medicine

Molecular Genetic Medicine
  • Author : Theodore Friedmann
  • Publisher : Elsevier
  • Release : 22 October 2013
GET THIS BOOK Molecular Genetic Medicine

Molecular Genetic Medicine, Volume I, provides an overview of the progress in several of the most important areas of modern molecular genetics and medicine. The aim is to present a technical and historical picture of the concept that it is through a thorough understanding of genetics of all kinds of human diseases, even infectious diseases, that effective treatments will finally come. The book opens with a discussion of the origins and development of the Human Genome Project. This is followed

Materials Science and Engineering

Materials Science and Engineering
  • Author : Ke Wu,Bharath Natarajan,Lisa Morkowchuk,Mike Krein,Curt M. Breneman
  • Publisher : Elsevier Inc. Chapters
  • Release : 10 July 2013
GET THIS BOOK Materials Science and Engineering

The Materials Genome Initiative (MGI) was conceived as a unified effort to capture, curate, and exploit materials structure/property information on a grand scale to enable rapid, cost-effective development of novel materials with predictable properties. While the use of “genomic” methods to facilitate property prediction, virtual design, and discovery of materials is relatively new, the concepts driving the development of materials informatics are based, solidly, on the lessons learned during the development history of cheminformatics and bioinformatics. This chapter describes