Molecular Approach to Cancer Management

• Author : Gajanan V. Sherbet
• Publisher : Academic Press
• Release : 15 June 2017

Molecular Approach to Cancer Management discusses molecular mechanisms of cancer initiation, growth and secondary spread, emphasizing how this information can be used to devise new modes of treatment of cancer, especially in combatting secondary spread. The book addresses the basic concepts relating to cancer biology, the genetic determinants, and the signal transduction cascades associated with tumor growth, EMT, stem cell maintenance and propagation, and invasion and metastasis. The salient features of the signaling systems that are amenable to targeted manipulation

• Author : Vincent T. DeVita,Vincent T. DeVita, Jr. M.D.,Theodore S. Lawrence,Steven A. Rosenberg
• Publisher : Lippincott Williams & Wilkins
• Release : 27 March 2023

Drawn from the content of the new Ninth Edition of Cancer: Principles and Practice of Oncology, this unique publication brings together the basic scientific information on the molecular biology of cancer. The format is designed to be useful both to research scientists interested in the study of cancer and to oncologists who need to understand these new developments that are having a profound impact on the care of patients with cancer. Leading scientists and clinicians in the field of molecular

• Author : Stella Pelengaris,Michael Khan
• Publisher : Wiley-Blackwell
• Release : 12 March 2009

This comprehensive text provides a detailed overview of the molecular mechanisms underpinning the development of cancer and its treatment. Written by an international panel of researchers, specialists and practitioners in the field, the text discusses all aspects of cancer biology from the causes, development and diagnosis through to the treatment of cancer. Written by an international panel of researchers, specialists and practitioners in the field Covers both traditional areas of study and areas of controversy and emerging importance, highlighting future

• Author : Marc E. Lippman,Robert B. Dickson
• Publisher : Springer Science & Business Media
• Release : 31 August 1988

Where do you begin to look for a recent, authoritative article on the diagnosis or management of particular malignancy? The few general oncology text books are generally out of date. Single papers in specialized journals are informative but seldom comprehensive; these are more often preliminary reports on a very limited number of patients. Certain general journals fre quently publish good in-depth reviews of cancer topics, and published sym posium lectures are often the best overviews available. Unfortunately, these reviews and

• Author : Catherine J. Cullinane,Susan A. Burchill,Jeremy A. Squire,John J. O'Leary,Ian J. Lewis
• Publisher : OUP Oxford
• Release : 13 November 2003

There has been an explosion of knowledge and enormous progress in the fundamental understanding of the biology of cancer in recent years. This has included the realisation that cancer occurs when normal cellular functions are disturbed leading to a malignant phenotype. Much research has focussed on understanding the types of disturbances that can occur, the contribution that these abnormalities can make to the development and behaviour of particular cancers and more recently, the recognition that these cellular and genetic abnormalities

• Author : Ashutosh Tewari
• Publisher : Springer Science & Business Media
• Release : 05 April 2013

Prostate cancer is the commonest male cancer with over 5 million survivors in US alone. Worldwide, the problem is staggering and has attracted significant attention by media, scientists and cancer experts. Significant research, discoveries, innovations and advances in treatment of this cancer have produced voluminous literature which is difficult to synthesize and assimilate by the medical community. Prostate Cancer: A Comprehensive Perspective is a comprehensive and definitive source which neatly resolves this problem. It covers relevant literature by leading experts in

• Author : Yusuf Tutar
• Publisher : Bentham Science Publishers
• Release : 08 June 2020

Nanotheranostics is a recent medical field which integrates diagnostic imaging protocols and therapeutic functions to monitor real time drug release in the body and distribution to the target site. The combined processes allow technicians to observe the effectiveness of a specifically designed drug candidate and predict its possible side effects. All these features help clinicians in optimizing treatment options for cancer and other diseases for the individual patient. Current research is tailored to individual therapy because each drug may display

• Author : Lisa Eileen Blumencranz
• Publisher : Unknown
• Release : 27 March 2023

Death from breast cancer began a decline in the 1990's. One widely accepted reason for this reduction was the discovery that breast cancer can be uniquely defined at the molecular level by oncogenes and tumor suppressor genes including, but not limited to, EGFR, AKT, ErbB2, PI3K, TP53, BRCA1/2, and PTEN. These genes and potential mutations within, can drive constitutive activation of aberrant signaling that can induce and sustain tumorigenesis. More importantly, these genes represent new avenues for possible markers

• Author : Louis B. Harrison,Roy B. Sessions,Waun Ki Hong
• Publisher : Lippincott Williams & Wilkins
• Release : 27 March 1999

This is a comprehensive guide to the care of patients with cancers of the head and neck. Coverage begins with reviews of the molecular biology and other basic science aspects of these cancers. The second section presents general principles of patient management, including physical examination, diagnostic imaging, head and neck pathology, dental oncology and maxillofacial prosthetics, nutritional management of the patient with head and neck cancer, head and neck oncologic nursing, reconstructive surgery, quality of life and psychiatric issues, and

• Author : Aysha Divan,Janice A. Royds
• Publisher : Oxford University Press, USA
• Release : 27 March 2020

This primer provides an overview of the complex processes underpinning cancer development and progression along with a summary of cancer treatment strategies, emphasising the development of targeted molecular therapies and the opportunities they provide. It takes a contemporary and integrated approach, encompassing debates on genetics, epigenetics, and cancer addictions, and highlighting the remaining challenges and future research directions to advance the field.

• Author : Nabil F. Saba,Bassel F. El-Rayes
• Publisher : Springer
• Release : 12 August 2015

​This book reviews the recent progress made in the prevention, diagnosis, and treatment of esophageal cancer. Epidemiology, molecular biology, pathology, staging, and prognosis are first discussed. The radiologic assessment of esophageal cancer and the role of endoscopy in diagnosis, staging, and management are then described. The principles of surgical resection, radiation therapy, and systemic chemotherapy for esophageal cancer are explained, and particular attention is paid to the multidisciplinary management of early-stage cervical, thoracic, distal, and junctional tumors. Up-to-date information is

• Author : Fiona Macdonald,Christopher Ford,Alan Casson
• Publisher : Garland Science
• Release : 15 January 2004

Molecular Biology of Cancer has been extensively revised and covers heredity cancer, microarray technology and increased study of childhood cancers. It continues to provide a detailed overview of the process which lead to the development and proliferation of cancer cells, including the techniques available for their study. It also describes the means by which tumor suppressor genes and oncogenes may be used in the diagnosis and in determining the prognosis of a wide variety of cancers, including breast, genitourinary, lung

• Author : Charles Brenner,David Duggan
• Publisher : John Wiley & Sons
• Release : 19 November 2004

This book aims to assemble the only available rigorous, yet broadly accessible introduction to this new and exciting field. Oncogenomics: Molecular Approaches to Cancer is approachable by basic scientists, practitioners, and other health professionals required to familiarize themselves with the tremendous impact of genomics and proteomics on cancer research. Clearly written chapters offer reviews of state of the art topics such as molecular classification, early detection, SNPs in cancer, data mining, tissue microarrays, protein and antibody arrays, and drug targets.

• Author : Miguel H. Bronchud
• Publisher : Springer Science & Business Media
• Release : 03 December 2003

At the midpoint of the 20th century, our knowledge of cancer was based on epide- ology and pathology, and treatment consisted of surgery and radiation therapy. At mid-century, Medawar and colleagues initiated the understanding of transplantation immunology, Farber described the first use of an antifolic drug to treat leukemia, and Jacobson and coworkers described the irradiation-protection effect of spleen cells. These observations opened the door to the development of chemotherapy and tra- plantation in the treatment of cancer. Despite the

• Author : Lauren Pecorino
• Publisher : Oxford University Press, USA
• Release : 27 March 2023

"The most engaging and accessible account of cancer biology that makes the link between our understanding of cancer and the development of new therapeutics crystal clear. -- Molecular Biology of Cancer: Mechanisms, Targets, and Therapeutics offers an engaging and manageable route into the complex subject of cancer biology. Using the hallmarks of cancer as a foundation, the book describes the cellular and molecular mechanisms underpinning the transformation of healthy cells into cancer cells. -- after discussing a specific biological hallmark