Models of Seizures and Epilepsy

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  • Author : Asla Pitkänen
  • Publisher : Academic Press
  • Pages : 1178 pages
  • ISBN : 012804067X
  • Rating : /5 from reviews
CLICK HERE TO GET THIS BOOK >>>Models of Seizures and Epilepsy

Download or Read online Models of Seizures and Epilepsy full in PDF, ePub and kindle. this book written by Asla Pitkänen and published by Academic Press which was released on 14 June 2017 with total page 1178 pages. We cannot guarantee that Models of Seizures and Epilepsy book is available in the library, click Get Book button and read full online book in your kindle, tablet, IPAD, PC or mobile whenever and wherever You Like. Models of Seizures and Epilepsy, Second Edition, is a valuable, practical reference for investigators who are searching for the most appropriate laboratory models to address key questions in the field. The book also provides an important background for physicians, fellows, and students, offering insight into the potential for advances in epilepsy research as well as R&D drug development. Contents include the current spectrum of models available to model different epilepsy syndromes, epilepsy in transgenic animals, comorbidities in models of epilepsy, and novel technologies to study seizures and epilepsies in animals. Provides a comprehensive reference detailing animal models of epilepsy and seizure Offers insights on the use of novel technologies that can be applied in experimental epilepsy research Edited by leading experts in the field that provide not only technical reviews of these models but also conceptual critiques Comments on the strengths and limitations of various models, including their relationship to clinical phenomenology and their value in developing better understanding and treatments

Models of Seizures and Epilepsy

Models of Seizures and Epilepsy
  • Author : Asla Pitkänen,Paul Buckmaster, DVM, PhD,Aristea S Galanopoulou,Solomon L. Moshé
  • Publisher : Academic Press
  • Release : 14 June 2017
GET THIS BOOK Models of Seizures and Epilepsy

Models of Seizures and Epilepsy, Second Edition, is a valuable, practical reference for investigators who are searching for the most appropriate laboratory models to address key questions in the field. The book also provides an important background for physicians, fellows, and students, offering insight into the potential for advances in epilepsy research as well as R&D drug development. Contents include the current spectrum of models available to model different epilepsy syndromes, epilepsy in transgenic animals, comorbidities in models of

Animal Models of Epilepsy

Animal Models of Epilepsy
  • Author : Scott C. Baraban
  • Publisher : Unknown
  • Release : 01 January 2009
GET THIS BOOK Animal Models of Epilepsy

Animal models provide a means to investigate fundamental mechanisms of abnormal electrical discharge i.e., seizures. Taking advantage of transgenic and homologous recombination techniques, laboratories have recently moved beyond the standard convulsant or stimulation models in rat to develop novel mouse models of epilepsy. This book provides a review of the current and emerging animal models used to study epilepsy. Prior textbooks devoted to models of seizure and epilepsy almost exclusively categorized rat models with little attention paid to these

Recent Advances in Predicting and Preventing Epileptic Seizures

Recent Advances in Predicting and Preventing Epileptic Seizures
  • Author : Ronald Tetzlaff,Christian E Elger,Klaus Lehnertz
  • Publisher : World Scientific
  • Release : 28 August 2013
GET THIS BOOK Recent Advances in Predicting and Preventing Epileptic Seizures

This book is to improve our understanding of mechanisms leading to seizures in humans and in developing new therapeutic options. The book covers topics such as recent approaches to seizure control, recent developments in signal processing of interest for seizure prediction, ictogenesis in complex epileptic brain networks, active probing of the pre-seizure state, non-EEG based approaches to the transition to seizures, microseizures and their role in the generation of clinical seizures, the impact of sleep and long-biological cycles on seizure

Experimental Models of Epilepsy and Related Comorbidities

Experimental Models of Epilepsy and Related Comorbidities
  • Author : Mohd. Farooq Shaikh,Ayanabha Chakraborti,Annamaria Vezzani,Jafri Malin Abdullah
  • Publisher : Frontiers Media SA
  • Release : 19 June 2019
GET THIS BOOK Experimental Models of Epilepsy and Related Comorbidities

Epileptic patients live with epilepsy-associated complications such as cognitive dysfunction, psychological discomfort, and sexual function decline, and are more likely to experience emotional and mental health issues problems, including depression and anxiety. Many antiepileptic drugs are found to have a role in aggravating psychiatric symptoms. Animal models, which inform translational questions about epilepsy comorbidities, are used to study the relationship between epilepsy and related comorbidities. The aim of this Research Topic was to highlight basic, clinical and interdisciplinary research involved

Behavioral Aspects of Epilepsy

Behavioral Aspects of Epilepsy
  • Author : Gregory L. Holmes, MD,Steven C. Schachter,Dr. Dorothee GA Kasteleijn-Nolst Trenite, "MD,MPH"
  • Publisher : Demos Medical Publishing
  • Release : 15 October 2007
GET THIS BOOK Behavioral Aspects of Epilepsy

The field of epilepsy and behavior has grown considerably in the past number of years, reflecting advances in the laboratory and clinic. Behavioral Aspects of Epilepsy: Principles and Practice is the definitive text on epilepsy behavioral issues, from basic science to clinical applications, for all neurologists, psychosocial specialists, and researchers in the fields of epilepsy, neuroscience, and psychology/psychiatry. Behavioral aspects of epilepsy include a patient's experiences during seizures, his or her reaction during and between seizures, the frequency of

Experimental and Translational Methods to Screen Drugs Effective Against Seizures and Epilepsy

Experimental and Translational Methods to Screen Drugs Effective Against Seizures and Epilepsy
  • Author : Divya Vohora
  • Publisher : Humana
  • Release : 23 June 2021
GET THIS BOOK Experimental and Translational Methods to Screen Drugs Effective Against Seizures and Epilepsy

This volume discusses the latest experimental and clinical approaches to study seizures and epilepsy. Chapters in this book cover detailed protocols for ex vivo and in vitro experimental models and widely-used in vivo (acute and chronic seizure) models in epilepsy research. Chapters also cover techniques to screen the effective leads for the treatment of refractory seizures of pharmacoresistant epilepsy and invertebrate, non-mammalian models. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists

Epileptic Seizures and the EEG

Epileptic Seizures and the EEG
  • Author : Andrea Varsavsky,Iven Mareels,Mark Cook
  • Publisher : CRC Press
  • Release : 19 April 2016
GET THIS BOOK Epileptic Seizures and the EEG

A study of epilepsy from an engineering perspective, this volume begins by summarizing the physiology and the fundamental ideas behind the measurement, analysis and modeling of the epileptic brain. It introduces the EEG and provides an explanation of the type of brain activity likely to register in EEG measurements, offering an overview of how these EEG records are and have been analyzed in the past. The book focuses on the problem of seizure detection and surveys the physiologically based dynamic

Astrocytes and Epilepsy

Astrocytes and Epilepsy
  • Author : Jacqueline A. Hubbard,Devin K. Binder
  • Publisher : Academic Press
  • Release : 05 July 2016
GET THIS BOOK Astrocytes and Epilepsy

Epilepsy is a devastating group of neurological disorders characterized by periodic and unpredictable seizure activity in the brain. There is a critical need for new drugs and approaches given than at least one-third of all epilepsy patients are not made free of seizures by existing medications and become "medically refractory". Much of epilepsy research has focused on neuronal therapeutic targets, but current antiepileptic drugs often cause severe cognitive, developmental, and behavioral side effects. Recent findings indicate a critical contribution of

Neuropharmacology Methods in Epilepsy Research

Neuropharmacology Methods in Epilepsy Research
  • Author : Steven L. Peterson,Timothy E. Albertson
  • Publisher : CRC Press
  • Release : 07 May 2019
GET THIS BOOK Neuropharmacology Methods in Epilepsy Research

There is an estimated 2.5 million epileptics in the US and perhaps some 40 million worldwide. As research has become increasingly molecular in scope, fewer scientists are trained in the US on basic, integrated epilepsy techniques. One frustration in neuroscience today is the application of state-of-the-art molecular biology techniques to inappropriate animal models of epilepsy - frequently resulting in inconclusive results. Epilepsy research will be increasingly undertaken by scientists well-trained in reductionist methodology, but who may be unfamiliar with integrated, whole-animal techniques.

Seizures and the Developing Brain

Seizures and the Developing Brain
  • Author : Aristea S. Galanopoulou
  • Publisher : Biota Publishing
  • Release : 01 October 2011
GET THIS BOOK Seizures and the Developing Brain

Seizures are more common early in life than in adulthood. Bidirectional interactions between seizures and normal developmental processes define their expression and outcomes. Several developmentally regulated factors control neuronal excitability. GABAA receptors hold a central role as they control neuronal activity in an age-specific manner. Early in development, GABAA receptors have depolarizing effects, which contribute to the increased susceptibility of immature neurons to seizures but they are also essential for normal brain development. During development, there is a gradual shift

Recent Advances in Predicting and Preventing Epileptic Seizures

Recent Advances in Predicting and Preventing Epileptic Seizures
  • Author : Ronald Tetzlaff,Christian Erich Elger,Klaus Lehnertz
  • Publisher : World Scientific Publishing Company Incorporated
  • Release : 08 December 2021
GET THIS BOOK Recent Advances in Predicting and Preventing Epileptic Seizures

This book is to improve our understanding of mechanisms leading to seizures in humans and in developing new therapeutic options. The book covers topics such as recent approaches to seizure control, recent developments in signal processing of interest for seizure prediction, ictogenesis in complex epileptic brain networks, active probing of the pre-seizure state, non-EEG based approaches to the transition to seizures, microseizures and their role in the generation of clinical seizures, the impact of sleep and long-biological cycles on seizure

Epileptic Seizures and the EEG

Epileptic Seizures and the EEG
  • Author : Andrea Varsavsky,Iven Mareels,Mark Cook
  • Publisher : CRC Press
  • Release : 19 April 2016
GET THIS BOOK Epileptic Seizures and the EEG

A study of epilepsy from an engineering perspective, this volume begins by summarizing the physiology and the fundamental ideas behind the measurement, analysis and modeling of the epileptic brain. It introduces the EEG and provides an explanation of the type of brain activity likely to register in EEG measurements, offering an overview of how these EEG records are and have been analyzed in the past. The book focuses on the problem of seizure detection and surveys the physiologically based dynamic

Antiepileptic Drugs

Antiepileptic Drugs
  • Author : M.J. Eadie,F. Vajda
  • Publisher : Springer Science & Business Media
  • Release : 06 December 2012
GET THIS BOOK Antiepileptic Drugs

In 1985, volume 74 of the Springer-Verlag Handbook of Experimental Phar macology, under the editorship of H. -H. Frey and D. Janz, appeared. In this volume the then available data on the topic of antiepileptic drugs were col lated and analysed. Over the intervening years knowledge in this area has grown progressively. More new antiepileptic drugs than the total number of agents that were in common use 15 years ago have in the interval either come on to the market or are about

Bundle for Epilepsy Researchers

Bundle for Epilepsy Researchers
  • Author : Ruben Kuzniecky,Asla Pitknen,Ivan Soltesz
  • Publisher : Academic Press
  • Release : 03 October 2008
GET THIS BOOK Bundle for Epilepsy Researchers

Combining three essential Academic Press books, this bundle provides reference information for epilepsy researchers at a great price. Magnetic Resonance in Epilepsy is an in-depth look at the advances in imaging techology as applied to epilepsy research. Models of Seizures and Epilepsy speaks to the needs of both basic neuroscientists and clinical neurologists, in understanding the pathophysiology of seizures and the epilepsies and predicting the clinical effectiveness of antiepileptic treatments. Computational Neuroscience in Epilepsy is the first-ever book solely dedicated