Mitochondria in Obesity and Type 2 Diabetes

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  • Author : Beatrice Morio
  • Publisher : Academic Press
  • Pages : 459 pages
  • ISBN : 0128118598
  • Rating : /5 from reviews
CLICK HERE TO GET THIS BOOK >>>Mitochondria in Obesity and Type 2 Diabetes

Download or Read online Mitochondria in Obesity and Type 2 Diabetes full in PDF, ePub and kindle. this book written by Beatrice Morio and published by Academic Press which was released on 13 April 2019 with total page 459 pages. We cannot guarantee that Mitochondria in Obesity and Type 2 Diabetes book is available in the library, click Get Book button and read full online book in your kindle, tablet, IPAD, PC or mobile whenever and wherever You Like. Mitochondria in Obesity and Type 2 Diabetes: Comprehensive Review on Mitochondrial Functioning and Involvement in Metabolic Diseases synthesizes discoveries from laboratories around the world, enhancing our understanding of the involvement of mitochondria in the etiology of diseases, such as obesity and type 2 diabetes. Chapters illustrate and provide an overview of key concepts on topics such as the role of mitochondria in adipose tissue, cancer, cardiovascular comorbidities, skeletal muscle, the liver, kidney, and more. This book is a must-have reference for students and educational teams in biology, physiology and medicine, and researchers. Synthesizes actual knowledge on mitochondrial function Provides an integrated vision of each tissue in the etiology of obesity and type 2 diabetes Identifies the interactive networks that involve alteration in mitochondrial mass and function in disease progression Highlights the role played by mitochondria in the prevention and treatment of obesity and type 2 diabetes

Mitochondria in Obesity and Type 2 Diabetes

Mitochondria in Obesity and Type 2 Diabetes
  • Author : Beatrice Morio,Luc Penicaud,Michel Rigoulet
  • Publisher : Academic Press
  • Release : 13 April 2019
GET THIS BOOK Mitochondria in Obesity and Type 2 Diabetes

Mitochondria in Obesity and Type 2 Diabetes: Comprehensive Review on Mitochondrial Functioning and Involvement in Metabolic Diseases synthesizes discoveries from laboratories around the world, enhancing our understanding of the involvement of mitochondria in the etiology of diseases, such as obesity and type 2 diabetes. Chapters illustrate and provide an overview of key concepts on topics such as the role of mitochondria in adipose tissue, cancer, cardiovascular comorbidities, skeletal muscle, the liver, kidney, and more. This book is a must-have reference for students

Targeting Mitochondrial Pathways in Obesity and Type 2 Diabetes

Targeting Mitochondrial Pathways in Obesity and Type 2 Diabetes
  • Author : Jessica Erin Sacks
  • Publisher : Unknown
  • Release : 21 June 2021
GET THIS BOOK Targeting Mitochondrial Pathways in Obesity and Type 2 Diabetes

Obesity is one of the largest medical epidemics our society faces today. There are over forty obesity-associated diseases that affect nearly every organ system in the body, including Type 2 Diabetes (T2D) and Non-Alcoholic Fatty Liver Disease (NAFLD). Insulin resistance is one of the hallmark characteristics underlying metabolic diseases, and mitochondrial dysfunction is believed to be a central player in this phenomenon, yet our understanding of the specific molecular mechanisms that serve as cause and consequence of defective mitochondria remain

Nutrition and Skeletal Muscle

Nutrition and Skeletal Muscle
  • Author : Stéphane Walrand
  • Publisher : Academic Press
  • Release : 24 October 2018
GET THIS BOOK Nutrition and Skeletal Muscle

Nutrition and Skeletal Muscle provides coverage of the evidence of dietary components that have proven beneficial for bettering adverse changes in skeletal muscle from disuse and aging. Skeletal muscle is the largest tissue in the body, providing elements of contraction and locomotion and acting as an important contributor to whole body protein and amino metabolism, glucose disposal and lipid metabolism. However, muscle loss, atrophy or weakness can occur when there are metabolic imbalances, disuse or aging. This book addresses the

Treatment of Type 2 Diabetes

Treatment of Type 2 Diabetes
  • Author : Colleen Croniger
  • Publisher : BoD – Books on Demand
  • Release : 01 April 2015
GET THIS BOOK Treatment of Type 2 Diabetes

Obesity and type 2 diabetes are increasing worldwide problems. In this book we reviewed factors that contribute to glucose homeostasis and the pathogenesis of Type 2 diabetes. In addition the book addresses current strategies for treatment of Type 2 Diabetes.

Bifurcation of in Vivo Hepatic Energy Metabolism and Glucose Production in Insulin Resistance and Diabetes

Bifurcation of in Vivo Hepatic Energy Metabolism and Glucose Production in Insulin Resistance and Diabetes
  • Author : Santhosh Satapati,University of Texas at Dallas. Graduate Program in Molecular and Cell Biology
  • Publisher : Unknown
  • Release : 21 June 2021
GET THIS BOOK Bifurcation of in Vivo Hepatic Energy Metabolism and Glucose Production in Insulin Resistance and Diabetes

Obesity and type 2 diabetes are modern epidemics, closely associated with the development of insulin resistance. While lipid induced mitochondrial dysfunction plays an important role in skeletal muscle insulin resistance, it is unclear whether a similar etiology is responsible for hepatic insulin resistance. The purpose of this thesis is to investigate whether impaired mitochondrial function plays a role in hepatic insulin resistance, and if so, whether it is a cause or consequence of insulin resistance. I further put forth the hypothesis

Mitochondrial Oxidative Capacity In Human Skeletal Muscle Association with Plasma Lactate Concentration

Mitochondrial Oxidative Capacity In Human Skeletal Muscle  Association with Plasma Lactate Concentration
  • Author : Jessica Lynn Cook
  • Publisher : Unknown
  • Release : 21 June 2021
GET THIS BOOK Mitochondrial Oxidative Capacity In Human Skeletal Muscle Association with Plasma Lactate Concentration

ABSTRACT Background: Metabolic disease is a growing concern for public health. Obesity and Type II Diabetes are an epidemic and a phenotype for insulin resistance in human skeletal muscle. A reduced mitochondrial function and oxidative capacity may be associated with impairments in fatty acid oxidation, which can lead to insulin resistance and metabolic dysfunction. While reductions in mitochondrial content may be a predictive variable, reductions in mitochondrial proteins and an increase in peroxisomal proteins may be contributing factors to increases

Assessing the Mediating Effect of Obesity Linked SNPs in Nuclear Mitochondrial Genes on Exercise Enhanced Insulin Sensitivity

Assessing the Mediating Effect of Obesity Linked SNPs in Nuclear Mitochondrial Genes on Exercise Enhanced Insulin Sensitivity
  • Author : Kaitlin Erin Bessinger
  • Publisher : Unknown
  • Release : 21 June 2021
GET THIS BOOK Assessing the Mediating Effect of Obesity Linked SNPs in Nuclear Mitochondrial Genes on Exercise Enhanced Insulin Sensitivity

Research shows that mitochondrial function and insulin resistance go hand in hand. As mitochondrial oxidative capacity is decreased, individuals are more likely to become insulin resistant and to develop type 2 diabetes. Exercise is known to increase mitochondrial oxidative capacity, helping these individuals enhance their insulin sensitivity. There are many genetic risk factors that are known to predispose individuals to type 2 diabetes and other metabolic disorders, some of which may limit the beneficial effects of exercise. I hypothesized that Single Nucleotide

Fatty Acid and Lipotoxicity in Obesity and Diabetes

Fatty Acid and Lipotoxicity in Obesity and Diabetes
  • Author : Gregory R. Bock,Jamie A. Goode
  • Publisher : John Wiley & Sons
  • Release : 11 March 2008
GET THIS BOOK Fatty Acid and Lipotoxicity in Obesity and Diabetes

The potential lipotoxic effect of accumulation of fatty acids in non-adipose tissues is thought to be a major component in the development of insulin resistance. Chronic exposure to high concentrations of free fatty acids in the blood affects pancreatic β cell function, insulin secretion and lipid synthesis in the liver, and storage in adipose tissue. Maintaining the normal levels of fatty acids requires coordinated regulation between the liver, adipose tissue and skeletal muscle. This book deals with the molecular aspects of

Glucotoxicity mediated U03b2 Cell Dysfunction Related to ER mitochondria Ca2 Exchange and Mitochondria Fission in U03b2 Cells

Glucotoxicity mediated U03b2 Cell Dysfunction Related to ER mitochondria Ca2  Exchange and Mitochondria Fission in U03b2 Cells
  • Author : Anne-Marie Madec
  • Publisher : Unknown
  • Release : 21 June 2021
GET THIS BOOK Glucotoxicity mediated U03b2 Cell Dysfunction Related to ER mitochondria Ca2 Exchange and Mitochondria Fission in U03b2 Cells

Beta cell dysfunction in type 2 diabetes (T2D) is associated with glucotoxicity-mediated alterations of both mitochondria and endoplasmic reticulum (ER). Both organelles interact at contact sites, defined as mitochondria-associated membranes (MAMs), and disruption of ER-mitochondria interactions was recently involved in hepatic (1) and muscle (2) insulin resistance and alterations of glucose homeostasis (3) and that organelle miscommunication was associated with insulin resistance in various mice models of obesity and T2D (1-4) . However, the role of MAMs in u00df cells is still