Mitochondria and Brain Disorders

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  • Author : Stavros Baloyannis
  • Publisher : BoD – Books on Demand
  • Pages : 124 pages
  • ISBN : 1789855314
  • Rating : /5 from reviews
CLICK HERE TO GET THIS BOOK >>>Mitochondria and Brain Disorders

Download or Read online Mitochondria and Brain Disorders full in PDF, ePub and kindle. this book written by Stavros Baloyannis and published by BoD – Books on Demand which was released on 11 March 2020 with total page 124 pages. We cannot guarantee that Mitochondria and Brain Disorders book is available in the library, click Get Book button and read full online book in your kindle, tablet, IPAD, PC or mobile whenever and wherever You Like. The mitochondrion is a unique and ubiquitous organelle that contains its own genome, encoding essential proteins that are major components of the respiratory chain and energy production system. Mitochondria play a dominant role in the life and function of eukaryotic cells including neurons and glia, as their survival and activity depend upon mitochondrial energy production and supply. Besides energy production, mitochondria also play a vital role in calcium homeostasis and may induce apoptosis by excitotoxicity. Mitochondrial dysfunction is related to common neurological diseases, such as Parkinson's disease, Alzheimer's disease, Friedreich's ataxia, Huntington's disease, and Multiple Sclerosis. An efficient treatment of mitochondrial dysfunction would open new horizons in the therapeutic perspectives of a substantial number of inflammatory and degenerative neurological disorders.

Mitochondria and Brain Disorders

Mitochondria and Brain Disorders
  • Author : Stavros Baloyannis
  • Publisher : BoD – Books on Demand
  • Release : 11 March 2020
GET THIS BOOK Mitochondria and Brain Disorders

The mitochondrion is a unique and ubiquitous organelle that contains its own genome, encoding essential proteins that are major components of the respiratory chain and energy production system. Mitochondria play a dominant role in the life and function of eukaryotic cells including neurons and glia, as their survival and activity depend upon mitochondrial energy production and supply. Besides energy production, mitochondria also play a vital role in calcium homeostasis and may induce apoptosis by excitotoxicity. Mitochondrial dysfunction is related to

Mitochondria in Neurological Disorders

Mitochondria in Neurological Disorders
  • Author : Rajat Sandhir
  • Publisher : Academic Press
  • Release : 15 June 2022
GET THIS BOOK Mitochondria in Neurological Disorders

Mitochondria in Neurological Diseases highlights various therapeutic approaches targeting mitochondria in neurological conditions. Focused on diverse neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, Huntington's disease, depression, and Amyotrophic lateral sclerosis, topics span basic mitochondrial physiology to mitochondrial dynamics and to the altered states of the nervous system. This book is appropriate for anyone interested in learning more about the physiological and pathophysiological functions of mitochondria in the nervous system. Provides up-to-date information on role of mitochondria in nervous system

The Functions Disease Related Dysfunctions and Therapeutic Targeting of Neuronal Mitochondria

The Functions  Disease Related Dysfunctions  and Therapeutic Targeting of Neuronal Mitochondria
  • Author : J. Marie Hardwick
  • Publisher : John Wiley & Sons
  • Release : 19 October 2015
GET THIS BOOK The Functions Disease Related Dysfunctions and Therapeutic Targeting of Neuronal Mitochondria

This book presents advances in the field of neuronal mitochondria – functions, relation to therapeutics, and pharmacology. For scientists and researchers in both industry and academia, this book provides detailed discussion, examples, and approaches, to illustrate the potential of mitochondria as therapeutic targets for neuronal diseases. • Helps readers understand the regulation of mitochondrial cellular processes, such as substrate metabolism, energy production, and programmed versus sporadic cell death • Offers insights on the development of strategies for targeted therapeutic approaches and potential personalized

Mitochondrial Dysfunction in Neurodegenerative Disorders

Mitochondrial Dysfunction in Neurodegenerative Disorders
  • Author : Amy Katherine Reeve,Kim Jennifer Krishnan,Michael R. Duchen,Doug M Turnbull
  • Publisher : Springer Science & Business Media
  • Release : 15 November 2011
GET THIS BOOK Mitochondrial Dysfunction in Neurodegenerative Disorders

As age related diseases increase in prevalence and impact more significantly on medical resources it is imperative to understand these diseases and the mechanisms behind their progression. New research has stimulated a growing interest in mitochondrial involvement in neurodegenerative disorders such as Parkinson’s disease, Alzheimer’s disease and multiple sclerosis and the mechanisms which lead from mitochondrial dysfunction to neurodegeneration. Mitochondrial Dysfunction in Neurodegenerative Disorders brings together contributions from leaders in the field internationally on the various ways in

Diagnosis and Management of Mitochondrial Disorders

Diagnosis and Management of Mitochondrial Disorders
  • Author : Michelangelo Mancuso,Thomas Klopstock
  • Publisher : Springer
  • Release : 30 March 2019
GET THIS BOOK Diagnosis and Management of Mitochondrial Disorders

This book will help readers navigate the complexity of mitochondrial disorders, by addressing the role of mitochondrial dysfunction and the complex pathophysiological mechanisms associated with a growing number of illnesses, not only of neurological interest. Further, it provides updated concepts on genotype-phenotype correlations, clinical syndromes, diagnostic algorithms and therapies. Written by the world’s foremost mitochondrial researchers, the book comprehensively presents the state-of-the-art in mitochondrial medicine, making it of interest to a wide variety of specialists, including neurologists, geneticists, internists

Mitochondrial Dynamics and Neurodegeneration

Mitochondrial Dynamics and Neurodegeneration
  • Author : Bingwei Lu
  • Publisher : Springer Science & Business Media
  • Release : 16 May 2011
GET THIS BOOK Mitochondrial Dynamics and Neurodegeneration

Mitochondria are essential organelles in eukaryotic cells that control such diverse processes as energy metabolism, calcium buffering, and cell death. Recent studies have revealed that changes in mitochondrial morphology by fission and fusion, a process known as mitochondrial dynamics, is particularly important for neuronal function and survival. Defects in this process are commonly found in neurodegenerative diseases, offering a new paradigm for investigating mechanisms of neurodegeneration. To provide researchers working on neurodegenerative diseases and mitochondria with updated information on this

Pharmacology of Mitochondria

Pharmacology of Mitochondria
  • Author : Harpreet Singh,Shey-Shing Sheu
  • Publisher : Springer
  • Release : 11 August 2017
GET THIS BOOK Pharmacology of Mitochondria

This special book is conceived to highlight mitochondrial structural and functional integrity and how they are associated with several human diseases such as cardiovascular, cancer, renal, neurological disorder, and genetic disorders. The chapters contributed by leading mitochondrial researchers in the handbook will take us through the novel pharmacological strategies via mitochondria to understand their physiological and pathological role as well as present them as therapeutic targets.

Mitochondria dependent Local Caspase Activation and Mitofusin 2 mediated Mitophagy in Neurodegeneration

Mitochondria dependent Local Caspase Activation and Mitofusin 2 mediated Mitophagy in Neurodegeneration
  • Author : Hao Chen
  • Publisher : Unknown
  • Release : 03 October 2022
GET THIS BOOK Mitochondria dependent Local Caspase Activation and Mitofusin 2 mediated Mitophagy in Neurodegeneration

Mitochondria are critical regulators of neuronal physiology. They play a pivotal role in energy supply and Ca2+ buffering. Thus, mitochondria can sustain the synapse and neuronal function. In this regard, the mitochondria with an impaired capacity of bioenergetics or Ca2+ buffering will lead to synapse failure and neurodegeneration. Moreover, emerging evidence has shown that damaged mitochondria are also involved in local caspase activation, which coincides with spine pruning and neurodegeneration. However, the impacts of local caspase signaling on spine dynamics

Mitochondrial Dynamics and Neurodegeneration

Mitochondrial Dynamics and Neurodegeneration
  • Author : Bingwei Lu
  • Publisher : Springer
  • Release : 02 January 2013
GET THIS BOOK Mitochondrial Dynamics and Neurodegeneration

Mitochondria are essential organelles in eukaryotic cells that control such diverse processes as energy metabolism, calcium buffering, and cell death. Recent studies have revealed that changes in mitochondrial morphology by fission and fusion, a process known as mitochondrial dynamics, is particularly important for neuronal function and survival. Defects in this process are commonly found in neurodegenerative diseases, offering a new paradigm for investigating mechanisms of neurodegeneration. To provide researchers working on neurodegenerative diseases and mitochondria with updated information on this

Mitochondria and the Future of Medicine

Mitochondria and the Future of Medicine
  • Author : Lee Know
  • Publisher : Chelsea Green Publishing
  • Release : 19 February 2018
GET THIS BOOK Mitochondria and the Future of Medicine

With information for patients and practitioners on optimizing mitochondrial function for greater health and longevity Why do we age? Why does cancer develop? What's the connection between heart failure and Alzheimer's disease, or infertility and hearing loss? Can we extend lifespan, and if so, how? What is the Exercise Paradox? Why do antioxidant supplements sometimes do more harm than good? Many will be amazed to learn that all these questions, and many more, can be answered by a single point

Molecular Basis of Neurological Disorders and Their Treatment

Molecular Basis of Neurological Disorders and Their Treatment
  • Author : J.W. Gorrod,A. Albano,E. Ferrari,S. Papa
  • Publisher : Springer Science & Business Media
  • Release : 06 December 2012
GET THIS BOOK Molecular Basis of Neurological Disorders and Their Treatment

cytochemical techniques (ICC) which provide a useful adjunct to investigations by immunoblotting. A particular advantage of a cytochemical approach to the investiga tion of mitochondrial disorders is that it allows the mosaic distribution of certain of these defects to be detected, whereas the tissue homogeniza tion involved in conventional enzyme assays or immunoblotting precludes this. A further advantage of MEA or ICC is that only small amounts of tissue are needed, which is important since many of the affected patients

Mitochondrial Disorders in Neurology

Mitochondrial Disorders in Neurology
  • Author : Anthony H.V. Schapira,S. Dimauro
  • Publisher : Butterworth-Heinemann
  • Release : 22 October 2013
GET THIS BOOK Mitochondrial Disorders in Neurology

Mitochondrial Disorders in Neurology provides an overview of mitochondrial diseases. This book discusses the effects of mitochondrial dysfunction based on the relevant biochemistry and molecular genetics. The abnormal muscle and mitochondrial morphology in a variety of clinical presentations from isolated ophthalmoplegia to severe encephalopathy are also elaborated. This text likewise deliberates Leber's hereditary optic neuropathy, neurodegenerative disorders, and respiratory chain defects. Other topics covered include mitochondrial DNA and the genetics of mitochondrial disease; cytochrome oxidase deficiency; use of tissue culture