Late Stage Fluorination of Bioactive Molecules and Biologically Relevant Substrates

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  • Author : Al Postigo
  • Publisher : Elsevier
  • Pages : 390 pages
  • ISBN : 0128130393
  • Rating : /5 from reviews
CLICK HERE TO GET THIS BOOK >>>Late Stage Fluorination of Bioactive Molecules and Biologically Relevant Substrates

Download or Read online Late Stage Fluorination of Bioactive Molecules and Biologically Relevant Substrates full in PDF, ePub and kindle. this book written by Al Postigo and published by Elsevier which was released on 05 September 2018 with total page 390 pages. We cannot guarantee that Late Stage Fluorination of Bioactive Molecules and Biologically Relevant Substrates book is available in the library, click Get Book button and read full online book in your kindle, tablet, IPAD, PC or mobile whenever and wherever You Like. Late-Stage Fluorination of Bioactive Molecules and Biologically-Relevant Substrates reviews how the use of these techniques on compounds with already known and relevant biological activity can provide new pharmaceutical leads with improved medicinal properties. The fluorination strategies discussed take into account both conventional and novel reagents, including nucleophilic, electrophilic, those of a radical nature, and diverse families of organic compounds, such as (hetero) aromatic rings and aliphatic substrates. Drawing on the authors' expert knowledge, this book provides researchers with a broad set of applicable methods to use in their work. Highlights the latest developments in the field in a concise volume Provides details of key fluorinating reagents across diverse families of organic compounds Explores the current applications and future potential of fluorine in drug development

Late Stage Fluorination of Bioactive Molecules and Biologically Relevant Substrates

Late Stage Fluorination of Bioactive Molecules and Biologically Relevant Substrates
  • Author : Al Postigo
  • Publisher : Elsevier
  • Release : 05 September 2018
GET THIS BOOK Late Stage Fluorination of Bioactive Molecules and Biologically Relevant Substrates

Late-Stage Fluorination of Bioactive Molecules and Biologically-Relevant Substrates reviews how the use of these techniques on compounds with already known and relevant biological activity can provide new pharmaceutical leads with improved medicinal properties. The fluorination strategies discussed take into account both conventional and novel reagents, including nucleophilic, electrophilic, those of a radical nature, and diverse families of organic compounds, such as (hetero) aromatic rings and aliphatic substrates. Drawing on the authors' expert knowledge, this book provides researchers with a broad

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Nontraditional Activation Methods in Green and Sustainable Applications
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  • Publisher : Elsevier
  • Release : 28 February 2021
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Nontraditional Activation Methods in Green and Sustainable Applications: Microwaves; Ultrasounds; Photo-, Electro- and Mechan-ochemistry and High Hydrostatic Pressure provides a broad overview of non-traditional activation methods to help readers identify and use appropriate approaches in reducing the environmental impact of their work. Sections discuss the fundamental principles of each method and provide examples of their practical use, illustrating their usefulness. Given the importance of expanding laboratory based technologies to the industrial level, chapters that cover both existing and potential industrial

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  • Publisher : John Wiley & Sons
  • Release : 05 January 2021
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By presenting novel methods for the efficient preparation of fluorinated compounds and their application in pharmaceutical and agrochemical chemistry as well as medicine, this is a valuable source of information for all researchers in academia and industry!

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  • Publisher : Royal Society of Chemistry
  • Release : 09 December 2021
GET THIS BOOK C H and C X Bond Functionalization

Cross-coupling reactions involving C-H and C-X bond functionalisation are commonplace in natural product synthesis and natural products, therapeutic agents, biological probes, and advanced materials. Much attention has been given to understanding the mechanistic strategies used to achieve this, making this a hot topic in recent years. In this edited book, contributions from across the globe examine these strategies, with a particular focus on palladium and copper, as well as iron u an emerging element in this field. Reviewing the recent

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  • Author : Dominique Cahard,Jun-An Ma
  • Publisher : John Wiley & Sons
  • Release : 10 April 2020
GET THIS BOOK Emerging Fluorinated Motifs

A must-have resource for all the researchers working in the organofluorine and related fields This timely two-volume set uniquely focuses on emerging fluorinated motifs beyond R-CF3 and R-F, like R-CF2H, R-OCF3, R-SCF3 and R-SF5. It also offers descriptions of the properties, synthesis, and applications of these emerging fluorinated motifs in order to help readers design new chemical entities, while providing new interest for researchers in organofluorine chemistry and new tools for those in other areas. Emerging Fluorinated Motifs: Synthesis,

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  • Author : Sabine Berteina-Raboin
  • Publisher : MDPI
  • Release : 13 February 2020
GET THIS BOOK Catalyzed Mizoroki Heck Reaction or C H activation

In the last few decades, research on the elaboration by palladium-catalytic processes of C-C bonds or the activation of C–H bonds has increased considerably. Yet there is still room for much improvement in terms of selectivity, or enantioselectivity, via the development of new ligands or the study of the catalytic effect of other metals to carry out the same chemical transformations. In addition, the attention paid to environmentally friendly methods in terms of the quantities of catalysts, ligands, and

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  • Author : Anonim
  • Publisher : Academic Press
  • Release : 27 August 2016
GET THIS BOOK Peptide Protein and Enzyme Design

De Novo Enzyme Design, the newest volume in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume includes the design of metal binding maquettes, insertion of non-natural cofactors, Cu metallopeptides, non-covalent interactions in peptide assemblies, peptide binding and bundling, heteronuclear metalloenzymes, florinated peptides, De Novo imaging agents, and protein-protein interaction. Continues the legacy of this premier serial with quality chapters on de novo enzyme design Represents