Inhaled Medicines

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  • Author : Stavros Kassinos
  • Publisher : Academic Press
  • Pages : 438 pages
  • ISBN : 0128149744
  • Rating : /5 from reviews
CLICK HERE TO GET THIS BOOK >>>Inhaled Medicines

Download or Read online Inhaled Medicines full in PDF, ePub and kindle. this book written by Stavros Kassinos and published by Academic Press which was released on 05 February 2021 with total page 438 pages. We cannot guarantee that Inhaled Medicines book is available in the library, click Get Book button and read full online book in your kindle, tablet, IPAD, PC or mobile whenever and wherever You Like. Inhaled medicines are widely used to treat pulmonary and systemic diseases. The efficacy and safety of these medicines can be influenced by the deposited fraction, the regional deposition pattern within the lungs and by post-depositional events such as drug dissolution, absorption and clearance from the lungs. Optimizing performance of treatments thus requires that we understand and are able to quantify these product and drug attributes. Inhaled Medicines: Optimizing Development through Integration of In Silico, In Vitro and In Vivo Approaches explores the current state of the art with respect to inhalation drug delivery, technologies available to assess product performance, and novel in silico methods now available to link in vitro product performance to clinical performance. Recent developments in the latter field, especially the prospect of integration of three-dimensional Computational Fluid Particle Methods (3D-CFPD) with physiologically based pharmacokinetic (PBPK models), unlocks the potential for in silico population studies that can help inform and optimize treatment and product development strategies. In this highly multidisciplinary field, where progress occurs at the intersection of several disciplines of engineering and science, this work aims to integrate current knowledge and understanding and to articulate a clear vision for future developments. ? Considers the healthcare needs driving the field, and where inhaled drugs could have the maximum impact ? Gives a concise account of the state of the art in key areas and technologies such as device and formulation technologies, clinically relevant in vitro performance assessment, medical imaging, as well as in silico modelling and simulation ? Articulates how the combination of in vitro product performance data, medical imaging and simulations technologies in the framework of large scale in silico pre-clinical trials could revolutionize the field ? Provides systematic and thorough referencing to sources offering a more-in-depth analysis of technical issues

Inhaled Medicines

Inhaled Medicines
  • Author : Stavros Kassinos,Per Bäckman,Joy Conway,Anthony J. J. Hickey
  • Publisher : Academic Press
  • Release : 05 February 2021
GET THIS BOOK Inhaled Medicines

Inhaled medicines are widely used to treat pulmonary and systemic diseases. The efficacy and safety of these medicines can be influenced by the deposited fraction, the regional deposition pattern within the lungs and by post-depositional events such as drug dissolution, absorption and clearance from the lungs. Optimizing performance of treatments thus requires that we understand and are able to quantify these product and drug attributes. Inhaled Medicines: Optimizing Development through Integration of In Silico, In Vitro and In Vivo Approaches

Inhaled Medicines

Inhaled Medicines
  • Author : Stavros Kassinos,Per Bäckman,Joy Conway,Anthony J. J. Hickey
  • Publisher : Academic Press
  • Release : 20 January 2021
GET THIS BOOK Inhaled Medicines

Inhaled medicines are widely used to treat pulmonary and systemic diseases. The efficacy and safety of these medicines can be influenced by the deposited fraction, the regional deposition pattern within the lungs and by post-depositional events such as drug dissolution, absorption and clearance from the lungs. Optimizing performance of treatments thus requires that we understand and are able to quantify these product and drug attributes. Inhaled Medicines: Optimizing Development through Integration of In Silico, In Vitro and In Vivo Approaches

The Mechanics of Inhaled Pharmaceutical Aerosols

The Mechanics of Inhaled Pharmaceutical Aerosols
  • Author : Warren H. Finlay
  • Publisher : Academic Press
  • Release : 15 June 2019
GET THIS BOOK The Mechanics of Inhaled Pharmaceutical Aerosols

The Mechanics of Inhaled Pharmaceutical Aerosols, Second Edition provides a concise but thorough exposition of the fundamental concepts in the field of pharmaceutical aerosols. The field of inhaled pharmaceutical aerosols has grown rapidly since the original edition was published in 2001. The revised edition will allow researchers in the field to gain an up-to-date, thorough understanding of the field from first principles, allowing them to understand, design, develop and improve inhaled pharmaceutical aerosol devices and therapies. The first four chapters provide

Pharmacology and Therapeutics of Asthma and COPD

Pharmacology and Therapeutics of Asthma and COPD
  • Author : Clive P. Page,Peter J. Barnes
  • Publisher : Springer
  • Release : 06 February 2017
GET THIS BOOK Pharmacology and Therapeutics of Asthma and COPD

The present volume is supposed to be a major reference resource for chest physicians and those involved in the development of novel pharmaceutical entities for these diseases. Internationally recognized authorities review the most important new information on the advances in our understanding of the pathogenesis and treatment of these diseases, including the substantial advances in the topical delivery of inhaled medicines. Each chapter is extensively referenced, generously illustrated with clear diagrams and photographs, and represents a state-of-the-art review of this

Nanoparticles in medicine and environment

Nanoparticles in medicine and environment
  • Author : J.C. Marijnissen,Leon Gradon
  • Publisher : Springer Science & Business Media
  • Release : 01 December 2009
GET THIS BOOK Nanoparticles in medicine and environment

A huge effort is put into the science of nanoparticles and their production. In many cases it is unavoidable that nanoparticles are released into the environment, either during the production processes or during the use of a product made from these particles. It is also realized that combustion processes like traffic and power plants release nanoparticles into the atmosphere. However it is not known how nanoparticles interact with the human body, especially upon inhalation. At the same time research activities

Pulmonary Drug Delivery

Pulmonary Drug Delivery
  • Author : Ali Nokhodchi,Gary P. Martin
  • Publisher : John Wiley & Sons
  • Release : 18 May 2015
GET THIS BOOK Pulmonary Drug Delivery

Drug therapy via inhalation route is at the cutting edge of modern drug delivery research. There has been significant progress on the understanding of drug therapy via inhalation products. However, there are still problems associated with their formulation design, including the interaction between the active pharmaceutical ingredient(s) (APIs), excipients and devices. This book seeks to cover some of the most pertinent issues and challenges of such formulation design associated with industrial production and desirable clinical outcome. The chapter topics

Aerosols in Medicine

Aerosols in Medicine
  • Author : Folke Morén
  • Publisher : Elsevier Science Limited
  • Release : 16 September 1993
GET THIS BOOK Aerosols in Medicine

This edition includes chapters on the diagnostic and therapeutic use of aerosols, systemic therapy, and particle size analysis of therapeutic aerosols. It reviews the current state-of-the-art, details important applications and assesses environmental and occupational aerosols.

Lung Disposition Model based Analyses of Clinical Pharmacokinetic Profiles for Inhaled Drugs

Lung Disposition Model based Analyses of Clinical Pharmacokinetic Profiles for Inhaled Drugs
  • Author : Anuja Raut
  • Publisher : Unknown
  • Release : 16 September 2021
GET THIS BOOK Lung Disposition Model based Analyses of Clinical Pharmacokinetic Profiles for Inhaled Drugs

There has been a desire to accurately interpret the inhaled pharmacokinetic (PK) profiles of drugs in humans to aid successful inhaled drug and product developments. However, challenges are layered, as 1) the drug dose delivered to the lung (DTL) from inhalers is a portion of the formulated dose but rarely determined; 2) lung delivery and regional deposition differ, depending on drug, formulation and inhaler; 3) drugs are not only absorbed from the lung but may also be from the gastrointestinal (GI) tract; and 4)

Cases illustrative of the efficacy of various medicines administered by inhalation in preliminary consumption in certain morbid states of the trachea and bronchial tubes attended with distressing cough and in asthma

Cases illustrative of the efficacy of various medicines administered by inhalation  in preliminary consumption  in certain morbid states of the trachea and bronchial tubes  attended with distressing cough  and in asthma
  • Author : Sir Charles SCUDAMORE
  • Publisher : Unknown
  • Release : 16 September 2021
GET THIS BOOK Cases illustrative of the efficacy of various medicines administered by inhalation in preliminary consumption in certain morbid states of the trachea and bronchial tubes attended with distressing cough and in asthma

Pharmaceutical Inhalation Aerosol Technology Third Edition

Pharmaceutical Inhalation Aerosol Technology  Third Edition
  • Author : Anthony J. Hickey,Sandro R. da Rocha
  • Publisher : CRC Press
  • Release : 26 March 2019
GET THIS BOOK Pharmaceutical Inhalation Aerosol Technology Third Edition

This fully revised and updated third edition of Pharmaceutical Inhalation Aerosol Technology encompasses the scientific and technical foundation for the rationale, design, componentry, assembly and quality performance metrics of therapeutic inhalers in their delivery of pharmaceutical aerosols to treat symptoms or the underlying causes of disease. It focuses on the importance of pharmaceutical engineering as a foundational element of all inhaler products and their application to pulmonary drug delivery. The expanded scope considers previously unaddressed aspects of pharmaceutical inhalation aerosol

Everything You Wanted to Know about Asthma

Everything You Wanted to Know about Asthma
  • Author : Ashok Birbal Jain
  • Publisher : Pustak Mahal
  • Release : 07 June 2004
GET THIS BOOK Everything You Wanted to Know about Asthma

An estimated 15 million Indians suffer from asthma. the ailment remains mostly a life-long problem that cannot be cured completely. However, the attacks can be prevented or controlled. For this, one must understand the causes, treatment options, lifestyle changes etc. Doctors are reluctant to use steroids, fearing their side- effects. Inhalation therapy is also not used optimally. With over 20 years experience in treating asthma, the doctor couple cover all these aspects in their book. Some patients are reluctant to use allopathy.