In Vitro Toxicology Second Edition

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  • Author : Shayne C. Gad
  • Publisher : CRC Press
  • Pages : 419 pages
  • ISBN : 1560327693
  • Rating : /5 from reviews
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Download or Read online In Vitro Toxicology Second Edition full in PDF, ePub and kindle. this book written by Shayne C. Gad and published by CRC Press which was released on 02 November 2000 with total page 419 pages. We cannot guarantee that In Vitro Toxicology Second Edition book is available in the library, click Get Book button and read full online book in your kindle, tablet, IPAD, PC or mobile whenever and wherever You Like. Toxicology has made tremendous strides in the sophistication of the models used to identify and understand the mechanisms of agents that can harm or kill humand and other higher organisms. Non-animals or in vitro models started to gain significant use in the 1960s. As a result of the increased concern over animal welfare, economic factors, and the need for greater sensitivity and understanding of mechanisms, interest in in vitro^n models has risen. This volume demonstrates that there now exists a broad range of in vitro models for use in either identifying or understanding most forms of toxicity. The availability of in vitro models spans both the full range of endpoints (irritation, sensitization, lethality, mutagenicity, and devlopmental toxicity) and the full spectrum of target organ systems (skin, eye, heart, liver, kidney, nervous system, etc.). Chapters are devoted to each of these speciality areas from a perspective of presenting the principal models and their uses and limitations. Chapters that overview the principles involved in the general selection and use of models, and that address the issues of safety concerns and regulatory acceptance of these methods are also included.

In Vitro Toxicology Second Edition

In Vitro Toxicology  Second Edition
  • Author : Shayne C. Gad
  • Publisher : CRC Press
  • Release : 02 November 2000
GET THIS BOOK In Vitro Toxicology Second Edition

Toxicology has made tremendous strides in the sophistication of the models used to identify and understand the mechanisms of agents that can harm or kill humand and other higher organisms. Non-animals or in vitro models started to gain significant use in the 1960s. As a result of the increased concern over animal welfare, economic factors, and the need for greater sensitivity and understanding of mechanisms, interest in in vitro^n models has risen. This volume demonstrates that there now exists

Cell Culture Methods for In Vitro Toxicology

Cell Culture Methods for In Vitro Toxicology
  • Author : G. Stacey,Alan Doyle,Margherita Ferro
  • Publisher : Springer Science & Business Media
  • Release : 29 June 2013
GET THIS BOOK Cell Culture Methods for In Vitro Toxicology

Cell Culture Methods for in vitro Toxicology introduces the reader to a range of techniques involved in the use of in vitro cell culture in toxicological studies. It deals with major cell types studied in the field of toxicology and will be useful for anyone wishing to start work with animal cell cultures or to refresh their knowledge relating to in vitro cell models. Fundamental chapters deal with the general biology of cytotoxicity and cell immortalisation these are key issues

Principles of Toxicology Testing Second Edition

Principles of Toxicology Testing  Second Edition
  • Author : Frank A Barile
  • Publisher : CRC Press
  • Release : 02 April 2013
GET THIS BOOK Principles of Toxicology Testing Second Edition

Nationally, toxicology programs have evolved from a traditional exploration of the chemistry and applied toxicity of chemicals and drugs to a more comprehensive study of toxicology and toxicology testing as independent entities. Consequently, the second edition of Principles of Toxicology Testing starts with basic toxicological principles, including absorption, distribution, metabolism, and elimination of toxins, including chemicals and drugs. The book then continues with animal (in vivo) and in vitro toxicology testing methods associated with toxicological analysis and preclinical drug development.

In Vitro Toxicology Systems

In Vitro Toxicology Systems
  • Author : Anna Bal-Price,Paul Jennings
  • Publisher : Humana Press
  • Release : 03 September 2016
GET THIS BOOK In Vitro Toxicology Systems

In Vitro Toxicology Systems brings together important issues and considerations needed in order to develop a workable, reliable, integrated testing strategy for the replacement of animals in toxicity testing regimes. This thorough volume includes sections on in vitro models for systemic organ toxicity, neurotoxicity, sensory organs, immunotoxicity and reproductive toxicity and addresses how stem cells may be used going forward. The book also tackles difficult areas of toxicology such as carcinogenicity and nanotoxicology, with additional chapters dedicated to kinetics, metabolism,

In Vitro Toxicity Testing Protocols

In Vitro Toxicity Testing Protocols
  • Author : Sheila O’Hare,Christopher K. Atterwill
  • Publisher : Humana Press
  • Release : 23 August 2013
GET THIS BOOK In Vitro Toxicity Testing Protocols

In vitro toxicology is one of the most rapidly expanding areas of biological research today. It is generally conceded that this is a result of pressure from the public for safer products and environmental conditions and, in these recessionary times, pressure from company accountants, who often perceive in vitro experimentation as a cheaper option than lawsuits, fines, and expensive remediation. Toxicologists themselves form one group whose vigor and influence on the evolution of in vitro toxicology is often underestimated. Many

Standard Operating Procedures In Vitro Toxicology

Standard Operating Procedures In Vitro Toxicology
  • Author : I.P. Sword,S.D. Thomson
  • Publisher : Springer
  • Release : 09 October 2011
GET THIS BOOK Standard Operating Procedures In Vitro Toxicology

When Volume 1 (Toxicolpgy) in this series of Standard Operating Procedures was pub lished in early 1979, the FDA's Good Laboratory Practice Regulations did not have the force of United States Law, but nevertheless had a substantial impact on the conduct of toxicology in laboratories throughout the world. These Regulations are now in force, and Volume 2 (Pathology) was published later the same year. Our critics have implied that we have attempted to reduce toxicology to the level of the cookery book, or

In Vitro Toxicity Testing Protocols

In Vitro Toxicity Testing Protocols
  • Author : Sheila O’Hare,C. K. Atterwill
  • Publisher : Humana Press
  • Release : 04 May 1995
GET THIS BOOK In Vitro Toxicity Testing Protocols

In Vitro Toxicity Testing Protocols is a collection of proven, state-of-the-art methods that toxicologists can use in carrying out laboratory studies. The book's expert contributors offer a variety of efficient in vitro toxicology techniques that can be applied regularly in your lab, or can serve as the fundamental basis for the establishment of novel techniques in working laboratories. All the procedures are highly reliable. Also included are ex vivo techniques, whose development embraces the twin aims of reduction and refinement

Acute Toxicology Testing

Acute Toxicology Testing
  • Author : Shayne C. Gad,Christopher P. Chengelis
  • Publisher : Academic Press
  • Release : 27 October 1997
GET THIS BOOK Acute Toxicology Testing

Acute toxicology testing provides the first line of defense against potentially dangerous chemicals. This book is a complete and practical guide to conducting and interpreting all regulatory required and commonly used acute toxicity tests. It presents detailed protocols for all of the common test designs and reviews their development and objectives. Acute Toxicology Testing, Second Edition will interest not only workers in the pharmaceutical industry, but also researchers and students in toxicology and public health. Key Features * Over 100 tables summarizing

Cellular and Molecular Toxicology and In Vitro Toxicology

Cellular and Molecular Toxicology and In Vitro Toxicology
  • Author : Daniel Acosta
  • Publisher : CRC Press
  • Release : 28 July 2017
GET THIS BOOK Cellular and Molecular Toxicology and In Vitro Toxicology

This work concentrates on cellular and molecular toxicity of selected well-known drugs or chemicals on the cardiovascular system. The primary objective is to provide a better understanding of the mechanisms by which xenobiotics are toxic to mammalian tissues and cells. The use of in vitro cellular and tissue systems provides attractive experimental models to assess toxic manifestations of xenobiotics. This work addresses the most recent findings on the cellular and molecular mechanisms of toxicity of several important cardiotoxic agents: doxorubicin,

In Vitro Toxicity Testing

In Vitro Toxicity Testing
  • Author : John M. Frazier
  • Publisher : CRC Press
  • Release : 31 January 1992
GET THIS BOOK In Vitro Toxicity Testing

This volume focuses on the potential application of in vitro procedures to identify and quantify the toxicological risk to target organs associated with the use of commerical products and therapeutic drugs.;Revealing how the results of in vitro toxicity testing can be used in safety assessment, In Vitro Toxicity Testing: explores whether existing test methods can accomplish the necessary goals and, if not, what research is needed to make these techniques a practical reality; presents the current status of toxicity

In Vitro Toxicity Testing of Environmental Agents

In Vitro Toxicity Testing of Environmental Agents
  • Author : NATO Advanced Research Institute on in Vitro Toxicity Testing of Envi,North Atlantic Treaty Organization. Scientific Affairs Division,North Atlantic Treaty Organization
  • Publisher : Springer
  • Release : 01 February 1983
GET THIS BOOK In Vitro Toxicity Testing of Environmental Agents

These two volumes contain the papers presented at a North Atlantic Treaty Organization (NATO) Advanced Study Institute held on September 22-28, 1979 in Monte Carlo, Monaco. The conference was entitled "In Vitro Toxicity Testing of Environmental Agents: Current and Future Possibilities." This international conference presented an opportunity for the participants to exchange informa tion and ideas on the current approaches (both scientific and po litical) for toxic assessment of environmental agents. The poten tial health effects of these compounds as well