In Vitro Toxicology

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  • Author : Alok Dhawan
  • Publisher : Academic Press
  • Pages : 248 pages
  • ISBN : 0128047712
  • Rating : /5 from reviews
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Download or Read online In Vitro Toxicology full in PDF, ePub and kindle. this book written by Alok Dhawan and published by Academic Press which was released on 13 November 2017 with total page 248 pages. We cannot guarantee that In Vitro Toxicology book is available in the library, click Get Book button and read full online book in your kindle, tablet, IPAD, PC or mobile whenever and wherever You Like. In Vitro Toxicology details the protocols and methods of in vitro testing, highlighting the usefulness of models, methods and the cost-effectiveness and reproducibility of such methodologies. The current approaches and strategies required to develop an easy, reliable, validated and high throughput system for use in alternative animal models to circumvent in vivo testing are discussed in detail. The book also includes chapters on the principles involved in the general selection and use of models that address safety concerns, regulatory acceptance and the current understandings and strategies for the identification of biomarkers in toxicity testing. Furthermore, principles involved in the general selection and use of models that address the issues of safety concerns and regulatory acceptance of these models are discussed, making the book beneficial to students, scientists, and regulators working in toxicology, as well as those in the field of chemicals and the safety assessment of novel materials. Discusses new techniques and protocols in a clear and concise manner includes examinations of nanotoxicity, genotoxicity and carcinogenicity Explains practical laboratory methods and the theories behind in vitro testing

In Vitro Toxicology

In Vitro Toxicology
  • Author : Alok Dhawan,Seok (Soga) Kwon
  • Publisher : Academic Press
  • Release : 13 November 2017
GET THIS BOOK In Vitro Toxicology

In Vitro Toxicology details the protocols and methods of in vitro testing, highlighting the usefulness of models, methods and the cost-effectiveness and reproducibility of such methodologies. The current approaches and strategies required to develop an easy, reliable, validated and high throughput system for use in alternative animal models to circumvent in vivo testing are discussed in detail. The book also includes chapters on the principles involved in the general selection and use of models that address safety concerns, regulatory acceptance

In Vitro Toxicity Testing Protocols

In Vitro Toxicity Testing Protocols
  • Author : Sheila O’Hare,Christopher K. Atterwill
  • Publisher : Humana Press
  • Release : 23 August 2013
GET THIS BOOK In Vitro Toxicity Testing Protocols

In vitro toxicology is one of the most rapidly expanding areas of biological research today. It is generally conceded that this is a result of pressure from the public for safer products and environmental conditions and, in these recessionary times, pressure from company accountants, who often perceive in vitro experimentation as a cheaper option than lawsuits, fines, and expensive remediation. Toxicologists themselves form one group whose vigor and influence on the evolution of in vitro toxicology is often underestimated. Many

In Vitro Toxicology Second Edition

In Vitro Toxicology  Second Edition
  • Author : Shayne C. Gad
  • Publisher : CRC Press
  • Release : 02 November 2000
GET THIS BOOK In Vitro Toxicology Second Edition

Toxicology has made tremendous strides in the sophistication of the models used to identify and understand the mechanisms of agents that can harm or kill humand and other higher organisms. Non-animals or in vitro models started to gain significant use in the 1960s. As a result of the increased concern over animal welfare, economic factors, and the need for greater sensitivity and understanding of mechanisms, interest in in vitro^n models has risen. This volume demonstrates that there now exists

Standard Operating Procedures In Vitro Toxicology

Standard Operating Procedures In Vitro Toxicology
  • Author : I.P. Sword,S.D. Thomson
  • Publisher : Springer
  • Release : 09 October 2011
GET THIS BOOK Standard Operating Procedures In Vitro Toxicology

When Volume 1 (Toxicolpgy) in this series of Standard Operating Procedures was pub lished in early 1979, the FDA's Good Laboratory Practice Regulations did not have the force of United States Law, but nevertheless had a substantial impact on the conduct of toxicology in laboratories throughout the world. These Regulations are now in force, and Volume 2 (Pathology) was published later the same year. Our critics have implied that we have attempted to reduce toxicology to the level of the cookery book, or

In Vitro Toxicology Systems

In Vitro Toxicology Systems
  • Author : Anna Bal-Price,Paul Jennings
  • Publisher : Humana Press
  • Release : 03 September 2016
GET THIS BOOK In Vitro Toxicology Systems

In Vitro Toxicology Systems brings together important issues and considerations needed in order to develop a workable, reliable, integrated testing strategy for the replacement of animals in toxicity testing regimes. This thorough volume includes sections on in vitro models for systemic organ toxicity, neurotoxicity, sensory organs, immunotoxicity and reproductive toxicity and addresses how stem cells may be used going forward. The book also tackles difficult areas of toxicology such as carcinogenicity and nanotoxicology, with additional chapters dedicated to kinetics, metabolism,

Cell Culture Methods for In Vitro Toxicology

Cell Culture Methods for In Vitro Toxicology
  • Author : G. Stacey,Alan Doyle,Margherita Ferro
  • Publisher : Springer Science & Business Media
  • Release : 29 June 2013
GET THIS BOOK Cell Culture Methods for In Vitro Toxicology

Cell Culture Methods for in vitro Toxicology introduces the reader to a range of techniques involved in the use of in vitro cell culture in toxicological studies. It deals with major cell types studied in the field of toxicology and will be useful for anyone wishing to start work with animal cell cultures or to refresh their knowledge relating to in vitro cell models. Fundamental chapters deal with the general biology of cytotoxicity and cell immortalisation these are key issues

Cellular and Molecular Toxicology and In Vitro Toxicology

Cellular and Molecular Toxicology and In Vitro Toxicology
  • Author : Daniel Acosta
  • Publisher : CRC Press
  • Release : 28 July 2017
GET THIS BOOK Cellular and Molecular Toxicology and In Vitro Toxicology

This work concentrates on cellular and molecular toxicity of selected well-known drugs or chemicals on the cardiovascular system. The primary objective is to provide a better understanding of the mechanisms by which xenobiotics are toxic to mammalian tissues and cells. The use of in vitro cellular and tissue systems provides attractive experimental models to assess toxic manifestations of xenobiotics. This work addresses the most recent findings on the cellular and molecular mechanisms of toxicity of several important cardiotoxic agents: doxorubicin,

Principles of Toxicology Testing Second Edition

Principles of Toxicology Testing  Second Edition
  • Author : Frank A Barile
  • Publisher : CRC Press
  • Release : 02 April 2013
GET THIS BOOK Principles of Toxicology Testing Second Edition

Nationally, toxicology programs have evolved from a traditional exploration of the chemistry and applied toxicity of chemicals and drugs to a more comprehensive study of toxicology and toxicology testing as independent entities. Consequently, the second edition of Principles of Toxicology Testing starts with basic toxicological principles, including absorption, distribution, metabolism, and elimination of toxins, including chemicals and drugs. The book then continues with animal (in vivo) and in vitro toxicology testing methods associated with toxicological analysis and preclinical drug development.

Rapport Sur L tat Et Les Tendances de la Toxicologie in Vitro Et Modifications Des M thodologies Pour R duire L exp rimentation Animale

Rapport Sur L   tat Et Les Tendances de la Toxicologie in Vitro Et Modifications Des M  thodologies Pour R  duire L exp  rimentation Animale
  • Author : J. P. W. Gilman
  • Publisher : Division de la toxicologie des médicaments, Bureau de recherche sur les médicaments, Santé et bien-être social Canada
  • Release : 24 July 1991
GET THIS BOOK Rapport Sur L tat Et Les Tendances de la Toxicologie in Vitro Et Modifications Des M thodologies Pour R duire L exp rimentation Animale

The primary purposes of toxicological testing are the protection of human health and the safeguarding of the environment from excessive manmade contamination. Responsibility for setting safety standards and monitoring their implementation lies mainly with the federal departments of health, agriculture, and the environment. This report discusses in some detail the state-of-the-art of in vitro toxicology and other trends in alternative toxicological testing that may lead to a reduction in the use of animals for these purposes. It covers both the

In Vitro Toxicity Testing

In Vitro Toxicity Testing
  • Author : John M. Frazier
  • Publisher : CRC Press
  • Release : 31 January 1992
GET THIS BOOK In Vitro Toxicity Testing

This volume focuses on the potential application of in vitro procedures to identify and quantify the toxicological risk to target organs associated with the use of commerical products and therapeutic drugs.;Revealing how the results of in vitro toxicity testing can be used in safety assessment, In Vitro Toxicity Testing: explores whether existing test methods can accomplish the necessary goals and, if not, what research is needed to make these techniques a practical reality; presents the current status of toxicity