In Silico Drug Design

In Silico Drug Design Book PDF
✏Book Title : In Silico Drug Design
✏Author : Kunal Roy
✏Publisher : Academic Press
✏Release Date : 2019-02-12
✏Pages : 886
✏ISBN : 9780128163771
✏Available Language : English, Spanish, And French

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✏In Silico Drug Design Book Summary : In Silico Drug Design: Repurposing Techniques and Methodologies explores the application of computational tools that can be utilized for this approach. The book covers theoretical background and methodologies of chem-bioinformatic techniques and network modeling and discusses the various applied strategies to systematically retrieve, integrate and analyze datasets from diverse sources. Other topics include in silico drug design methods, computational workflows for drug repurposing, and network-based in silico screening for drug efficacy. With contributions from experts in the field and the inclusion of practical case studies, this book gives scientists, researchers and R&D professionals in the pharmaceutical industry valuable insights into drug design. Discusses the theoretical background and methodologies of useful techniques of cheminformatics and bioinformatics that can be applied for drug repurposing Offers case studies relating to the in silico modeling of FDA-approved drugs for the discovery of antifungal, anticancer, antiplatelet agents, and for drug therapies against diseases Covers tools and databases that can be utilized to facilitate in silico methods for drug repurposing

In Silico Methods For Drug Design And Discovery Book PDF
✏Book Title : In Silico Methods for Drug Design and Discovery
✏Author : Simone Brogi
✏Publisher : Frontiers Media SA
✏Release Date : 2020-10-09
✏Pages :
✏ISBN : 9782889660575
✏Available Language : English, Spanish, And French

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✏In Silico Methods for Drug Design and Discovery Book Summary :

📒In Silico Drug Discovery And Design ✍ Claudio N. Cavasotto

In Silico Drug Discovery And Design Book PDF
✏Book Title : In Silico Drug Discovery and Design
✏Author : Claudio N. Cavasotto
✏Publisher : CRC Press
✏Release Date : 2015-08-06
✏Pages : 558
✏ISBN : 9781482217858
✏Available Language : English, Spanish, And French

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✏In Silico Drug Discovery and Design Book Summary : In Silico Drug Discovery and Design: Theory, Methods, Challenges, and Applications provides a comprehensive, unified, and in-depth overview of the current methodological strategies in computer-aided drug discovery and design. Its main aims are to introduce the theoretical framework and algorithms, discuss the range of validity, strengths and limita

In Silico Medicinal Chemistry Book PDF
✏Book Title : In Silico Medicinal Chemistry
✏Author : Nathan Brown
✏Publisher : Royal Society of Chemistry
✏Release Date :
✏Pages :
✏ISBN : 9781782621638
✏Available Language : English, Spanish, And French

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✏In Silico Medicinal Chemistry Book Summary :

In Silico Drug Design For Staphylococcus Aureus And Development Of Host Pathogen Interaction Network Book PDF
✏Book Title : In Silico Drug Design for Staphylococcus Aureus and Development of Host pathogen Interaction Network
✏Author :
✏Publisher :
✏Release Date :
✏Pages :
✏ISBN : OCLC:1051399116
✏Available Language : English, Spanish, And French

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✏In Silico Drug Design for Staphylococcus Aureus and Development of Host pathogen Interaction Network Book Summary : Abstract: Staphylococcus aureus, a member of Staphylococcacea has been considered as an opportunistic pathogen in humans and livestock. Thus, the suggestion has been made to discover a potential drug to address Staphylococcus aureus infections. In the present study, drug designing of natural antistaphylococcal compounds, comprised of docking study of acetylated abietane quinone against ClfA (clumping factor A) using the AutoDock tool, was performed and the formed hydrogen bonds in the docked complex were analyzed using Pymol software. A drug library of 86 natural antistaphylococcal compounds was generated and screened with Lipinski and ADMET (Absorption, Distribution, Metabolism, Excretion, and Toxicity) filters using Molinspiration and PreADMET tools. A host-pathogen interaction network of Staphylococcus aureus and humans was developed using Cytoscape tool. After applying filters and performing an analysis, acetylated abietane quinone, which is a natural antistaphylococcal compound and a component of mint, was obtained. The binding energy of the docked complex of ligand acetylated abietane quinone against receptor ClfA was estimated to be −7.52kcal/mol, which showed good binding affinity. Thus, acetylated abietane quinone could serve as a drug for treating staphylococcal infections in humans. A total of 40 interactions between S.aureus and humans were identified and represented using the developed host-pathogen interaction network, which should provide a significant target-based drug discovery for treating S.aureus infections in humans.

Molecular Modelling And Drug Design Book PDF
✏Book Title : Molecular Modelling and Drug Design
✏Author : K Anand Solomon
✏Publisher : MJP Publisher
✏Release Date : 2019-06-05
✏Pages : 242
✏ISBN :
✏Available Language : English, Spanish, And French

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✏Molecular Modelling and Drug Design Book Summary : Molecular modelling is the scientific art of simulating chemicalor biological systems, so that computational methods can beapplied to understand the process concerned. Models usingcomputers are generated using mathematical equations and areevolved based on experimental information that is taken intoconsideration during model building. This book is anintroduction to the field of molecular modelling and drug designin which biological molecules effective in treating diseases arediscovered using in silico methods.

Chemoinformatics Approaches To Structure And Ligand Based Drug Design Book PDF
✏Book Title : Chemoinformatics Approaches to Structure and Ligand Based Drug Design
✏Author : Adriano D. Andricopulo
✏Publisher : Frontiers Media SA
✏Release Date : 2019-02-05
✏Pages :
✏ISBN : 9782889457441
✏Available Language : English, Spanish, And French

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✏Chemoinformatics Approaches to Structure and Ligand Based Drug Design Book Summary : Chemoinformatics is paramount to current drug discovery. Structure- and ligand-based drug design strategies have been used to uncover hidden patterns in large amounts of data, and to disclose the molecular aspects underlying ligand-receptor interactions. This Research Topic aims to share with a broad audience the most recent trends in the use of chemoinformatics in drug design. To that end, experts in all areas of drug discovery have made their knowledge available through a series of articles that report state-of-the-art approaches. Readers are provided with outstanding contributions focusing on a wide variety of topics which will be of great value to those interested in the many different and exciting facets of drug design.

📒Computer Aided Drug Design ✍ Dev Bukhsh Singh

Computer Aided Drug Design Book PDF
✏Book Title : Computer Aided Drug Design
✏Author : Dev Bukhsh Singh
✏Publisher : Springer Nature
✏Release Date : 2020-10-09
✏Pages : 306
✏ISBN : 9789811568152
✏Available Language : English, Spanish, And French

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✏Computer Aided Drug Design Book Summary : This book provides up-to-date information on bioinformatics tools for the discovery and development of new drug molecules. It discusses a range of computational applications, including three-dimensional modeling of protein structures, protein-ligand docking, and molecular dynamics simulation of protein-ligand complexes for identifying desirable drug candidates. It also explores computational approaches for identifying potential drug targets and for pharmacophore modeling. Moreover, it presents structure- and ligand-based drug design tools to optimize known drugs and guide the design of new molecules. The book also describes methods for identifying small-molecule binding pockets in proteins, and summarizes the databases used to explore the essential properties of drugs, drug-like small molecules and their targets. In addition, the book highlights various tools to predict the absorption, distribution, metabolism, excretion (ADME) and toxicity (T) of potential drug candidates. Lastly, it reviews in silico tools that can facilitate vaccine design and discusses their limitations.

Frontiers In Drug Design And Discovery Book PDF
✏Book Title : Frontiers in Drug Design and Discovery
✏Author : Atta-ur- Rahman
✏Publisher : Bentham Science Publishers
✏Release Date : 2009
✏Pages : 457
✏ISBN : 9781608052028
✏Available Language : English, Spanish, And French

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✏Frontiers in Drug Design and Discovery Book Summary : "Frontiers in Drug Design and Discovery" is an Ebook series devoted to publishing the latest and the most important advances in drug design and discovery. Eminent scientists write contributions on all areas of rational drug design and drug discovery inclu

Frontiers In Drug Design Discovery Book PDF
✏Book Title : Frontiers in Drug Design Discovery
✏Author : Atta-ur- Rahman
✏Publisher : Bentham Science Publishers
✏Release Date : 2018-08-01
✏Pages : 318
✏ISBN : 9781681085821
✏Available Language : English, Spanish, And French

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✏Frontiers in Drug Design Discovery Book Summary : Frontiers in Drug Design and Discovery Volume 9 is a book series devoted to publishing the latest and the most important advances in drug design and discovery. Eminent scientists have contributed chapters focused on all areas of rational drug design and drug discovery including medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, and structure-activity relationships. This book series should prove to be of interest to all pharmaceutical scientists who are involved in research in drug design and discovery and who wish to keep abreast of rapid and important developments in the field. The ninth volume of this series brings together reviews covering topics related to the treatment of neoplasms, systems biology, respiratory diseases among others. Topics included in this volume are: -Prognostic biomarkers in prostate cancer -Chemoresistance in cancer cells -GPCRS in systems and synthetic biology -Mechanisms of action of ribavirin in different diseases -Carbon nanotubes and drug targets -The role of phosphatase I inhibitors in Minkowski spaces -Phosphodiesterase targeting for treating respiratory diseases

📒Chemical Drug Design ✍ Girish Kumar Gupta

Chemical Drug Design Book PDF
✏Book Title : Chemical Drug Design
✏Author : Girish Kumar Gupta
✏Publisher : Walter de Gruyter GmbH & Co KG
✏Release Date : 2016-10-10
✏Pages : 297
✏ISBN : 9783110368826
✏Available Language : English, Spanish, And French

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✏Chemical Drug Design Book Summary : Chemical Drug Design provides a compact overview on recent advances in this rapidly developing field. With contributions on in silico drug design, natural product based compounds, as well as on ligand- and structure-based approaches, the authors present innovative methods and techniques for identifying and synthetically designing novel drugs.

Computer Aided Design Of Antimicrobial Lipopeptides As Prospective Drug Candidates Book PDF
✏Book Title : Computer Aided Design of Antimicrobial Lipopeptides as Prospective Drug Candidates
✏Author : Jujjvarapu Satya Eswari
✏Publisher : CRC Press
✏Release Date : 2019-09-16
✏Pages : 130
✏ISBN : 9781351018289
✏Available Language : English, Spanish, And French

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✏Computer Aided Design of Antimicrobial Lipopeptides as Prospective Drug Candidates Book Summary : Increase in antibiotic resistance has forced researchers to develop new drugs against microorganisms. Lipopeptides are produced as secondary metabolites by some microorganisms. Computer-aided Design of Antimicrobial Lipopeptides as Prospective Drug Candidates provides the identification of novel ligands for different antimicrobial lipopeptides. Along with identification, it also provides some of the in silico drug design processes, namely homology modelling, molecular docking, QSAR studies, drug ADMET studies and pharmacophore studies to check the ligand-lipopeptide interaction. Some lipopeptides have shown anti-cancerous properties too, and this book discusses the required templates to design new drugs using computational techniques. Key Features: Focuses on the use lipopeptides as new antimicrobial compounds Presents the basics of in silico modelling for design and development of new drug molecules, and is therefore of interest to beginners in the field Provides a step-by-step process for identification of drug molecules and testing its efficacy in silico Couples with courses on patents and intellectual property rights

Frontiers In Anti Cancer Drug Discovery Volume 1  Book PDF
✏Book Title : Frontiers in Anti Cancer Drug Discovery Volume 1
✏Author : Atta-ur- Rahman
✏Publisher : Bentham Science Publishers
✏Release Date : 2011-02-14
✏Pages : 779
✏ISBN : 9781608051618
✏Available Language : English, Spanish, And French

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✏Frontiers in Anti Cancer Drug Discovery Volume 1 Book Summary : "Frontiers in Anti-Cancer Drug Discovery" is an Ebook series devoted to publishing the latest and the most important advances in Anti-Cancer drug design and discovery. Eminent scientists write contributions on all areas of rational drug design and drug di

Conference On Drug Design And Discovery Technologies Book PDF
✏Book Title : Conference on Drug Design and Discovery Technologies
✏Author : Manikanta Murahari
✏Publisher : Royal Society of Chemistry
✏Release Date : 2019-11-20
✏Pages : 350
✏ISBN : 9781788018623
✏Available Language : English, Spanish, And French

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✏Conference on Drug Design and Discovery Technologies Book Summary : This publication is based on peer-reviewed manuscripts from the 2019 Conference on Drug Design & Discovery Technologies (CDDT) held at Ramaiah University of Applied Sciences, India. Providing a wide range of up to date topics on the latest advancements in drug design and discovery technologies, this book ensures the reader receives a good understanding of the scope of the field. Aimed at scientists, students, regulators, academics and consultants throughout the world, this book is an ideal resource for anyone interested in the state of the art in drug design and discovery.

Frontiers In Cns Drug Discovery Book PDF
✏Book Title : Frontiers in CNS Drug Discovery
✏Author : Atta-ur-Rahman
✏Publisher : Bentham Science Publishers
✏Release Date : 2013-09-10
✏Pages : 415
✏ISBN : 9781608057672
✏Available Language : English, Spanish, And French

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✏Frontiers in CNS Drug Discovery Book Summary : “Frontiers in CNS Drug Discovery” is an eBook series devoted to publishing the latest and the most important advances in Central Nervous System (CNS) drug design and discovery. Eminent scientists write contributions on all areas of rational drug design and drug discovery including medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships. The eBook series should prove to be of interest to all pharmaceutical scientists involved in research in CNS drug design and discovery. Each volume is devoted to the major advances in CNS drug design and discovery. The eBook series is essential reading to all scientists involved in drug design and discovery who wish to keep abreast of rapid and important developments in the field.

Frontiers In Cardiovascular Drug Discovery Book PDF
✏Book Title : Frontiers in Cardiovascular Drug Discovery
✏Author : Atta ur-Rahman
✏Publisher : Bentham Science Publishers
✏Release Date : 2015-01-02
✏Pages : 260
✏ISBN : 9781608059683
✏Available Language : English, Spanish, And French

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✏Frontiers in Cardiovascular Drug Discovery Book Summary : Frontiers in Cardiovascular Drug Discovery is an eBook series devoted to publishing the latest and the most important advances in Cardiovascular drug design and discovery. Eminent scientists write contributions on all areas of rational drug design and drug discovery including medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships. The eBook series should prove to be of interest to all pharmaceutical scientists involved in research in cardiovascular drug design and discovery. Each volume is devoted to the major advances in cardiovascular drug design and discovery. The eBook series is essential reading to all scientists involved in drug design and discovery who wish to keep abreast of rapid and important developments in the field.

Frontiers In Anti Cancer Drug Discovery Book PDF
✏Book Title : Frontiers in Anti Cancer Drug Discovery
✏Author : Atta-ur-Rahman
✏Publisher : Bentham Science Publishers
✏Release Date : 2013-11-29
✏Pages : 400
✏ISBN : 9781608058082
✏Available Language : English, Spanish, And French

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✏Frontiers in Anti Cancer Drug Discovery Book Summary : Frontiers in Anti-Cancer Drug Discovery is an Ebook series devoted to publishing the latest and the most important advances in Anti-Cancer drug design and discovery. Eminent scientists write contributions on all areas of rational drug design and drug discovery including medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships. The Ebook series should prove to be of interest to all pharmaceutical scientists involved in research in Anti-Cancer drug design and discovery. Each volume is devoted to the major advances in Anti-Cancer drug design and discovery. The Ebook series is essential reading to all scientists involved in drug design and discovery who wish to keep abreast of rapid and important developments in the field.

In Silico Technologies In Drug Target Identification And Validation Book PDF
✏Book Title : In Silico Technologies in Drug Target Identification and Validation
✏Author : Darryl Leon
✏Publisher : CRC Press
✏Release Date : 2006-06-13
✏Pages : 504
✏ISBN : 9781420015737
✏Available Language : English, Spanish, And French

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✏In Silico Technologies in Drug Target Identification and Validation Book Summary : The pharmaceutical industry relies on numerous well-designed experiments involving high-throughput techniques and in silico approaches to analyze potential drug targets. These in silico methods are often predictive, yielding faster and less expensive analyses than traditional in vivo or in vitro procedures. In Silico Technologies in Drug Target Identification and Validation addresses the challenge of testing a growing number of new potential targets and reviews currently available in silico approaches for identifying and validating these targets. The book emphasizes computational tools, public and commercial databases, mathematical methods, and software for interpreting complex experimental data. The book describes how these tools are used to visualize a target structure, identify binding sites, and predict behavior. World-renowned researchers cover many topics not typically found in most informatics books, including functional annotation, siRNA design, pathways, text mining, ontologies, systems biology, database management, data pipelining, and pharmacogenomics. Covering issues that range from prescreening target selection to genetic modeling and valuable data integration, In Silico Technologies in Drug Target Identification and Validation is a self-contained and practical guide to the various computational tools that can accelerate the identification and validation stages of drug target discovery and determine the biological functionality of potential targets more effectively. Daniel E. Levy, editor of the Drug Discovery Series, is the founder of DEL BioPharma, a consulting service for drug discovery programs. He also maintains a blog that explores organic chemistry.

📒Drug Design ✍ Kenneth M. Merz, Jr

Drug Design Book PDF
✏Book Title : Drug Design
✏Author : Kenneth M. Merz, Jr
✏Publisher : Cambridge University Press
✏Release Date : 2010-05-31
✏Pages : 274
✏ISBN : 9780521887236
✏Available Language : English, Spanish, And French

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✏Drug Design Book Summary : This book provides a complete snapshot of various experimental approaches to structure-based and ligand-based drug design and is illustrated with more than 200 images.

Pharmacophore Perception Development And Use In Drug Design Book PDF
✏Book Title : Pharmacophore Perception Development and Use in Drug Design
✏Author : Osman F. Güner
✏Publisher : Internat'l University Line
✏Release Date : 2000
✏Pages : 537
✏ISBN : 0963681761
✏Available Language : English, Spanish, And French

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✏Pharmacophore Perception Development and Use in Drug Design Book Summary : In the early 1900s, Paul Ehrlich first defined pharmacophores as molecule frameworks that carry the essential features responsible for a drug's biological activity, and the modern definition is little changed. The 27 studies here begin by tracing the evolution of the concept in pharmaceutical research, then cover analog-based and receptor-based varieties, new algorithms, and the future of research. Among the specific topics: pharmacophores based on multiple common-feature alignments; modeling programs including HypoGen, DISCO, Catalyst, HipHop, GASP, Chem-X, Apex-3D, CoMFA; pharmacophore-based molecular docking, a technique for developing a pharmacophore model that accommodates inherent protein flexibility; and the effect of variable weights and tolerances on predictive model generation. Books in Print lists only one other book on the topic of pharmacophores. Annotation copyrighted by Book News, Inc., Portland, OR

Thermodynamics And Kinetics Of Drug Binding Book PDF
✏Book Title : Thermodynamics and Kinetics of Drug Binding
✏Author : György Keserü
✏Publisher : John Wiley & Sons
✏Release Date : 2015-08-17
✏Pages : 360
✏ISBN : 9783527335824
✏Available Language : English, Spanish, And French

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✏Thermodynamics and Kinetics of Drug Binding Book Summary : This practical reference for medicinal and pharmaceutical chemists combines the theoretical background with modern methods as well as applications from recent lead finding and optimization projects. Divided into two parts on the thermodynamics and kinetics of drug-receptor interaction, the text provides the conceptual and methodological basis for characterizing binding mechanisms for drugs and other bioactive molecules. It covers all currently used methods, from experimental approaches, such as ITC or SPR, right up to the latest computational methods. Case studies of real-life lead or drug development projects are also included so readers can apply the methods learned to their own projects. Finally, the benefits of a thorough binding mode analysis for any drug development project are summarized in an outlook chapter written by the editors.

Structural Bioinformatics Applications In Preclinical Drug Discovery Process Book PDF
✏Book Title : Structural Bioinformatics Applications in Preclinical Drug Discovery Process
✏Author : C. Gopi Mohan
✏Publisher : Springer
✏Release Date : 2019-01-10
✏Pages : 406
✏ISBN : 9783030052829
✏Available Language : English, Spanish, And French

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✏Structural Bioinformatics Applications in Preclinical Drug Discovery Process Book Summary : This book reviews the advances and challenges of structure-based drug design in the preclinical drug discovery process, addressing various diseases, including malaria, tuberculosis and cancer. Written by internationally recognized researchers, this edited book discusses how the application of the various in-silico techniques, such as molecular docking, virtual screening, pharmacophore modeling, molecular dynamics simulations, and residue interaction networks offers insights into pharmacologically active novel molecular entities. It presents a clear concept of the molecular mechanism of different drug targets and explores methods to help understand drug resistance. In addition, it includes chapters dedicated to natural-product- derived medicines, combinatorial drug discovery, the CryoEM technique for structure-based drug design and big data in drug discovery. The book offers an invaluable resource for graduate and postgraduate students, as well as for researchers in academic and industrial laboratories working in the areas of chemoinformatics, medicinal and pharmaceutical chemistry and pharmacoinformatics.

📒Multi Scale Approaches In Drug Discovery ✍ Alejandro Speck-Planche

Multi Scale Approaches In Drug Discovery Book PDF
✏Book Title : Multi Scale Approaches in Drug Discovery
✏Author : Alejandro Speck-Planche
✏Publisher : Elsevier
✏Release Date : 2017-02-14
✏Pages : 238
✏ISBN : 9780081012420
✏Available Language : English, Spanish, And French

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✏Multi Scale Approaches in Drug Discovery Book Summary : Drug discovery is an expensive, time-consuming process and the modern drug discovery community is constantly challenged not only with discovering novel bioactive agents to combat resistance from known diseases and fight against new ones, but to do so in a way that is economically effective. Advances in both experimental and theoretical/computational methods envisage that the greatest challenges in drug discovery can be most successfully addressed by using a multi-scale approach, drawing on the specialties of a whole host of different disciplines. Multi-Scale Approaches to Drug Discovery furnishes chemists with the detail they need to identify drug leads with the highest potential before isolating and synthesizing them to produce effective drugs with greater swiftness than classical methods may allow. This significantly speeds up the search for more efficient therapeutic agents. After an introduction to multi-scale approaches outlining the need for and benefits of their use, the book goes on to explore a range of useful techniques and research areas, and their potential applications to this process. Profiling drug binding by thermodynamics, machine learning for predicting enzyme sub-classes, and multitasking models for computer-aided design and virtual compound screening are discussed, before the book goes on to review Alkaloid Menispermaceae leads, natural chemotherapeutic agents and methods for speeding up the design and virtual screening of therapeutic peptides. Flavonoids as multi-target compounds are then explored, before the book concludes with a review of Quasi-SMILES as a novel tool. Collecting together reviews and original research contributions written by leading experts in the field, Multi-Scale Approaches to Drug Discovery highlights cutting-edge approaches and practical examples of their implementation for those involved in the drug discovery process at many different levels. Using the combined knowledge of medicinal, computational, pharmaceutical and bio- chemists, it aims to support growth in the multi-scale approach to promote greater success in the development of new drugs. Offers practical guidance on ways to implement multiscale approaches for increased efficiency in drug discovery Draws on the experience of a highly skilled team of authors under the editorial guidance of one of the field's leading experts Includes cutting-edge techniques at the forefront of medicinal chemistry and drug discovery optimization

📒Virtual Drug Design ✍ Daniela Schuster

Virtual Drug Design Book PDF
✏Book Title : Virtual Drug Design
✏Author : Daniela Schuster
✏Publisher : Frontiers Media SA
✏Release Date : 2020-01-13
✏Pages :
✏ISBN : 9782889633593
✏Available Language : English, Spanish, And French

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✏Virtual Drug Design Book Summary : In the current drug research environment in academia and industry, cheminformatics and virtual screening methods are well established and integrated tools. Computational tools are used to predict a compound’s 3D structure, the 3D structure and function of a pharmacological target, ligand-target interactions, binding energies, and other factors essential for a successful drug. This includes molecular properties such as solubility, logP value, susceptibility to metabolism, cell permeation, blood brain barrier permeation, interaction with drug transporters and potential off-target effects. Given that approximately 40 million unique compounds are readily available for purchase, such computational modeling and filtering tools are essential to support the drug discovery and development process. The aim of all these calculations is to focus experimental efforts on the most promising candidates and exclude problematic compounds early in the project. In this Research Topic on virtual activity predictions, we cover several aspects of this research area such as historical perspectives, data sources, ligand treatment, virtual screening methods, hit list handling and filtering.

📒In Silico Lead Discovery ✍ Maria A. Miteva

In Silico Lead Discovery Book PDF
✏Book Title : In Silico Lead Discovery
✏Author : Maria A. Miteva
✏Publisher : Bentham Science Publishers
✏Release Date : 2011
✏Pages : 193
✏ISBN : 9781608051427
✏Available Language : English, Spanish, And French

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✏In Silico Lead Discovery Book Summary : Computer-aided drug design and in silico screening have contributed to the discovery of several compounds that have either reached the market or entered clinical trials. In silico Lead Discovery is a compilation of the efforts of several experts on bioinf

Frontiers In Anti Infective Drug Discovery Book PDF
✏Book Title : Frontiers in Anti Infective Drug Discovery
✏Author : Atta-ur-Rahman
✏Publisher : Bentham Science Publishers
✏Release Date : 2015-06-30
✏Pages : 230
✏ISBN : 9781681080826
✏Available Language : English, Spanish, And French

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✏Frontiers in Anti Infective Drug Discovery Book Summary : This eBook series brings updated reviews to readers interested in advances in the development of anti-infective drug design and discovery. The scope of the eBook series covers a range of topics including rational drug design and drug discovery, medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships. Frontiers in Anti-Infective Drug Discovery is a valuable resource for pharmaceutical scientists and post-graduate students seeking updated and critically important information for developing clinical trials and devising research plans in this field. The fourth volume of this series features 5 chapters that cover the following topics: - An overview of the incidence of neuraminadase resistance in influenza viruses in the Americas from 2004 to 2014 - Phenothiazines and derivative compounds for treating Trypanosoma cruzi infections - New antibacterial drug targets such as polysaccharide deacetylases - Improvements in aminoglycoside synthesis and biological activity (including RNA targeting) - A review of new chemotherapeutic agents against common infections.

Hpv Bioinformatics In Silico Detection Drug Design And Prevention Agent Development Book PDF
✏Book Title : HPV Bioinformatics In Silico Detection Drug Design and Prevention Agent Development
✏Author : Usman Sumo Friend
✏Publisher :
✏Release Date : 2012
✏Pages :
✏ISBN : OCLC:1154288188
✏Available Language : English, Spanish, And French

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✏HPV Bioinformatics In Silico Detection Drug Design and Prevention Agent Development Book Summary : HPV Bioinformatics: In Silico Detection, Drug Design and Prevention Agent Development.

Quantitative Structure Activity Relationships In Drug Design Predictive Toxicology And Risk Assessment Book PDF
✏Book Title : Quantitative Structure Activity Relationships in Drug Design Predictive Toxicology and Risk Assessment
✏Author : Roy, Kunal
✏Publisher : IGI Global
✏Release Date : 2015-02-28
✏Pages : 727
✏ISBN : 9781466681378
✏Available Language : English, Spanish, And French

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✏Quantitative Structure Activity Relationships in Drug Design Predictive Toxicology and Risk Assessment Book Summary : Quantitative structure-activity relationships (QSARs) represent predictive models derived from the application of statistical tools correlating biological activity or other properties of chemicals with descriptors representative of molecular structure and/or property. Quantitative Structure-Activity Relationships in Drug Design, Predictive Toxicology, and Risk Assessment discusses recent advancements in the field of QSARs with special reference to their application in drug development, predictive toxicology, and chemical risk analysis. Focusing on emerging research in the field, this book is an ideal reference source for industry professionals, students, and academicians in the fields of medicinal chemistry and toxicology.

Computer Applications In Drug Discovery And Development Book PDF
✏Book Title : Computer Applications in Drug Discovery and Development
✏Author : Puratchikody, A.
✏Publisher : IGI Global
✏Release Date : 2018-11-23
✏Pages : 332
✏ISBN : 9781522573272
✏Available Language : English, Spanish, And French

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✏Computer Applications in Drug Discovery and Development Book Summary : With more restrictions upon animal experimentations, pharmaceutical industries are currently focusing on a new generation of experiments and technologies that are considerably more efficient and less controversial. The integration of computational and experimental strategies has led to the identification and development of promising compounds. Computer Applications in Drug Discovery and Development is a pivotal reference source that provides innovative research on the application of computers for discovering and designing new drugs in modern molecular biology and medicinal chemistry. While highlighting topics such as chemical structure databases and dataset utilization, this publication delves into the current panorama of drug discovery, where high drug failure rates are a major concern and properly designed virtual screening strategies can be a time-saving, cost-effective, and productive alternative. This book is ideally designed for chemical engineers, pharmacists, molecular biologists, students, researchers, and academicians seeking current research on the unexplored avenues and future perspectives of drug design.

Frontiers In Cardiovascular Drug Discovery Volume 4 Book PDF
✏Book Title : Frontiers in Cardiovascular Drug Discovery Volume 4
✏Author : Atta-ur-Rahman
✏Publisher : Bentham Science Publishers
✏Release Date : 2019-04-05
✏Pages : 206
✏ISBN : 9781681084008
✏Available Language : English, Spanish, And French

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✏Frontiers in Cardiovascular Drug Discovery Volume 4 Book Summary : Frontiers in Cardiovascular Drug Discovery is an eBook series devoted to publishing the latest advances in cardiovascular drug design and discovery. Each volume brings reviews on the biochemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships of molecules used in cardiovascular therapy. The eBook series should prove to be of great interest to all medicinal chemists and pharmaceutical scientists involved in preclinical and clinical research in cardiology. The fourth volume of the series covers the following topics: -Aspirin administration -Adenosine receptor targeting for cardiovascular therapy -Drug treatment of patients with coronary stenting -Immunosuppressive drugs in heart transplantation -PCSK9 inhibition for lowering LDL-C levels.