Imaging of the Human Brain in Health and Disease

• Author : Philip Seeman,Bertha Madras
• Publisher : Elsevier
• Release : 15 November 2013

Brain imaging technology remains at the forefront of advances in both our understanding of the brain and our ability to diagnose and treat brain disease and disorders. Imaging of the Human Brain in Health and Disease examines the localization of neurotransmitter receptors in the nervous system of normal, healthy humans and compares that with humans who are suffering from various neurologic diseases. Opening chapters introduce the basic science of imaging neurotransmitters, including sigma, acetylcholine, opioid, and dopamine receptors. Imaging the

• Author : Philip Seeman,Bertha Madras
• Publisher : Academic Press
• Release : 04 February 2023

"Modern imaging techniques have allowed researchers to non-invasively peer into the human brain and investigate, among many other things, the acute effects and long-term consequences of drug abuse. Here, we review the most commonly used and some emerging imaging techniques in addiction research, explain how the various techniques generate their characteristic images and describe the rational that researchers use to interpret them. In addition, examples of seminal imaging findings are highlighted that illustrate the contribution of each imaging modality to

• Author : Cameron S. Carter,Jeffrey W. Dalley
• Publisher : Springer Science & Business Media
• Release : 04 November 2011

This volume highlights the remarkable new developments in brain imaging, including those that apply magnetic resonance imaging (MRI) and Positron Emission Tomography (PET), that allow us to non invasively study the living human brain in health and in disease. These technological advances have allowed us to obtain new and powerful insights into the structure and function of the healthy brain as it develops across the life cycle, as well as the molecular make up of brain systems and circuits as

• Author : Carole Escartin, Keith Murai
• Publisher : Frontiers Media SA
• Release : 25 November 2014

Astrocytes are key cellular partners to neurons in the brain. They play an important role in multiple processes such as neurotransmitter recycling, trophic support, antioxidant defense, ionic homeostasis, inflammatory modulation, neurovascular and neurometabolic coupling, neurogenesis, synapse formation and synaptic plasticity. In addition to their crucial involvement in normal brain physiology, it is well known that astrocytes adopt a reactive phenotype under most acute and chronic pathological conditions such as ischemia, trauma, brain cancer, epilepsy, demyelinating and neurodegenerative diseases. However, the

• Author : Dorina Papageorgiou,George Christopoulos,Stelios Smirnakis
• Publisher : BoD – Books on Demand
• Release : 31 May 2014

The brain is the most complex computational device we know, consisting of highly interacting and redundant networks of areas, supporting specific brain functions. The rules by which these areas organize themselves to perform specific computations have only now started to be uncovered. Advances in non-invasive neuroimaging technologies have revolutionized our understanding of the functional anatomy of cortical circuits in health and disease states, which is the focus of this book. The first section of this book focuses on methodological issues,

• Author : Angelo Mosso
• Publisher : Oxford University Press, USA
• Release : 04 February 2023

Modern brain imaging is revolutionizing the study of brain function in health and disease. Few realize that its origins began with a pioneering study in the nineteenth century by an Italian scientist, Angelo Mosso, of several subjects brought to him with head injuries that exposed their brains to direct observation. He took advantage of this opportunity to observe for the first time changes in cerebral blood flow in relation to different behaviors, the same changes that are the basis for

• Author : Francesco Fraioli
• Publisher : Springer
• Release : 05 March 2019

This well-illustrated pocket book offers up-to-date guidance on the clinical and research applications of PET/CT in the most common neurological and neuro-oncological disorders. The opening chapters cover the pros and cons of widely used radiological imaging techniques, scanners, and radiopharmaceuticals, with emphasis on the state of the art hybrid modalities, primarily PET/CT but also PET/MRI. Helpful information is provided on the clinical and research tracers used in neurodegenerative diseases, movement disorders, epilepsy and brain tumours. These four

• Author : Seiji Shioda,Ikuo Homma,Nobumasa Kato
• Publisher : Springer Science & Business Media
• Release : 25 July 2009

Prominent international researchers contributed to this volume of reports advancing the study of brain function and morphology. Comprising investigations in several areas of neuroscience, the book includes research in neurodegenerative diseases and in neuroregeneration in adults. Described here are the effects of neuropeptides and biogenic amines on feeding, respiration, and other autonomic functions as well as on behavior. One chapter focuses on regulation of the blood brain barrier function by various neuropeptides, proteins, receptors, and transporters. Another is concerned with

• Author : Lucio G Costa,Michael Aschner
• Publisher : Royal Society of Chemistry
• Release : 27 November 2014

Manganese in the diet is nutritionally essential for normal physiologic functioning. However, excessive exposure to manganese has been associated with developmental, neurodegenerative and other disorders. The book comprehensively covers the toxicology of manganese. Leading investigators provide perspectives from toxicology, neuroscience, nutrition, molecular biology and risk assessment disciplines and chapters cover the toxicokinetics, toxicodynamic interactions and health effects of manganese, as well as its potential role in neurodegenerative diseases. A large section devoted to health effects presents the latest research that

• Author : Alex Fornito,Andrew Zalesky,Edward Bullmore
• Publisher : Academic Press
• Release : 04 March 2016

Fundamentals of Brain Network Analysis is a comprehensive and accessible introduction to methods for unraveling the extraordinary complexity of neuronal connectivity. From the perspective of graph theory and network science, this book introduces, motivates and explains techniques for modeling brain networks as graphs of nodes connected by edges, and covers a diverse array of measures for quantifying their topological and spatial organization. It builds intuition for key concepts and methods by illustrating how they can be practically applied in diverse

• Author : Jack M. Gorman
• Publisher : Oxford University Press
• Release : 15 August 2018

Neuroscience, the study of the structure and function of the brain, has captured our imaginations. Breakthrough technologies permit neuroscientists to probe how the human brain works in ever-more fascinating detail, revealing what happens when we think, move, love, hate, and fear. We know more than ever before about what goes wrong in the brain when we develop psychiatric and neurological illnesses like depression, dementia, epilepsy, panic attacks, and schizophrenia. We also now have clues about how treatments for those disorders

• Author : United States. Congress. House. Committee on Science, Space, and Technology (2011)
• Publisher : Unknown
• Release : 04 February 2023

• Author : Anonim
• Publisher : Academic Press
• Release : 27 July 2013

This special volume of Progress in Molecular Biology and Translational Science focuses on chronobiology. Contributions from leading authorities Informs and updates on all the latest developments in the field

• Author : Chun Yuan,Thomas S. Hatsukami,Mahmud Mossa-Basha
• Publisher : Springer Nature
• Release : 10 October 2019

This book provides comprehensive information on new and existing vessel imaging techniques, with the intention of improving diagnosis, treatment, and prevention of vascular and related diseases. In recent years, vessel wall imaging has expanded greatly into other beds (such as the intracranial and peripheral arteries) and many of the techniques available for evaluation and diagnosis have only previously been published in research papers. This book bridges that gap for clinicians, applying cutting edge research to their everyday practice. The first

• Author : Henry Kennedy,David C. Van Essen,Yves Christen
• Publisher : Springer
• Release : 10 March 2016

This book has brought together leading investigators who work in the new arena of brain connectomics. This includes ‘macro-connectome’ efforts to comprehensively chart long-distance pathways and functional networks; ‘micro-connectome’ efforts to identify every neuron, axon, dendrite, synapse, and glial process within restricted brain regions; and ‘meso-connectome’ efforts to systematically map both local and long-distance connections using anatomical tracers. This book highlights cutting-edge methods that can accelerate progress in elucidating static ‘hard-wired’ circuits of the brain as well as dynamic interactions